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| 1 | Comprehensive and innovative techniques for livertransplantation in rats: A surgical guide显示文摘AIM: To investigate our learning curves of orthotopic liver transplantation (OLT) in rats and the most important factor for successful surgery. METHODS: We describe the surgical procedures for our rat OLT model, and determined the operator learning curves. The various factors that contributed to successful surgery were determined. The most important surgical factors were evaluated between successful and unsuccessful surgeries.RESULTS: Learning curve data indicated that 50 cases were required for operator training to start a study. Operative time, blood loss, warm ischemic time, anhepatic phase, unstable systemic hemodynamic state, and body temperature after surgery significantly affected surgery success by univariate analysis, while the anhepatic phase was the most critical factor for success by multivariate analysis. CONCLUSION: OLT in rats is the only liver transplantation model that provides clinically relevant and reliable results. Shortened anhepatic phase is key to success in this model. | Tomohide Hori Justin H Nguyen Yasuhiro Ogura Toshiyuki Hata Shintaro Yagi Ann-Marie T Baine Norifumi Ohashi Christopher B Eckman Aimee R Herdt Hiroto Egawa Yasutsugu Takada Fumitaka Oike Seisuke Saka-moto Mureo Kasahara Kohei Ogawa Koichiro Hata Taku Iida Yukihide Yonekawa Lena Sibulesky Kagemasa Kuribayashi Takuma Kato Kanako Saito Mie Torii Naruhiko Sahara Naoko Kamo Tomoko Sahara Motohiko Yasutomi Shinji Uemoto | 2010 | World Journal of Gastroenterology2010，16，25： | 14 |
| 2 | Changes in portal venous pressure in the early phase after living donor liver transplantation: pathogenesis and clinical implications1,2显示文摘 | Takashi Ito Tetsuya Kiuchi Hidekazu Yamamoto Fumitaka Oike Yasuhiro Ogura Yasuhiro Fujimoto Kazuhiro Hirohashi and Koichi Tanaka | 2003 | Transplantation2003，，8： | 3 |
| 3 | Protocol for laparoscopic cholecystectomy: Is it rocket science?显示文摘Laparoscopic cholecystectomy(LC) does not require advanced techniques, and its performance has therefore rapidly spread worldwide. However, the rate of biliary injuries has not decreased. The concept of the critical view of safety(CVS) was first documented two decades ago. Unexpected injuries are principally due to misidentification of human factors. The surgeon's assumption is a major cause of misidentification, and a high level of experience alone is not sufficient for successful LC. We herein describe tips and pitfalls of LC in detail and discuss various technical considerations.Finally, based on a review of important papers and our own experience, we summarize the following mandatory protocol for safe LC:(1) consideration that a high level of experience alone is not enough;(2) recognition of the plateau involving the common hepatic duct and hepatic hilum;(3) blunt dissection until CVS exposure;(4) Calot's triangle clearance in the overhead view;(5) Calot's triangle clearance in the view from underneath;(6) dissection of the posterior right side of Calot's triangle;(7) removal of the gallbladder body; and(8) positive CVS exposure. We believe that adherence to this protocol will ensure successful and beneficial LC worldwide, even in patients with inflammatory changes and rare anatomies. | Tomohide Hori Fumitaka Oike Hiroaki Furuyama Takafumi Machimoto Yoshio Kadokawa Toshiyuki Hata Shigeru Kato Daiki Yasukawa Yuki Aisu Maho Sasaki Yusuke Kimura Yuichiro Takamatsu Masato Naito Masaya Nakauchi Takahiro Tanaka Daigo Gunji Kiyokuni Nakamura Kiyoko Sato Masahiro Mizuno Taku Iida Shintaro Yagi Shinji Uemoto Tsunehiro Yoshimura | 2016 | World Journal of Gastroenterology2016，22，47： | 3 |
| 4 | Laparoscopic-assisted catheter insertion for continuous ambulatory peritoneal dialysis:A case report of simple technique for optimal placement显示文摘A 40-year-old male underwent tube placement surgery for continuous ambulatory peritoneal dialysis(CAPD).A2-cm skin incision was made,and the peritoneum was reflected enough to perform secure fixation.A swannecked,double-felted silicone CAPD catheter was inserted,and the felt cuff was sutured to the peritoneum to avoid postoperative leakage.An adequate gradient for tube fixation to the abdominal wall was confirmed.The CAPD tube was passed through a subcutaneous tunnel.Aeroperitoneum was induced to confirm that there was no air leakage from the sites of CAPD insertion.Two trocars were placed,and we confirmed that the CAPD tube led to the rectovesical pouch.Tip position was reliably observed laparoscopically.Optimal patency of the CAPD tube was confirmed during surgery.Placement of CAPD catheters by laparoscopic-assisted surgery has clear advantages in simplicity,safety,flexibility,and certainty.Laparoscopic technique should be considered the first choice for CAPD tube insertion. | Tomohide Hori Masaya Nakauchi Kazuhiro Nagao Fumitaka Oike Takahiro Tanaka Daigo Gunji Noriyuki Okada | 2013 | World Journal of Gastrointestinal Surgery2013，5，10： | 2 |
| 5 | Hematogenous umbilical metastasis from colon cancer treated by palliative single-incision laparoscopic surgery显示文摘Sister Mary Joseph’s nodule(SMJN)is a rare umbilical nodule that develops secondary to metastatic cancer.Primary malignancies are located in the abdomen or pelvis.Patients with SMJN have a poor prognosis.An 83-year-old woman presented to our hospital with a1-month history of a rapidly enlarging umbilical mass.Endoscopic findings revealed advanced transverse colon cancer.computer tomography and fluorodeoxyglucose-positron emission tomography revealed tumors of the transverse colon,umbilicus,right inguinal lymph nodes,and left lung.The feeding arteries and drainage veins for the SMJN were the inferior epigastric vessels.Imaging findings of the left lung tumor allowed for identification of the primary lung cancer,and a diagnosis of advanced transverse colon cancer with SMJN and primary lung cancer was made.The patient underwent local resection of the SMNJ and subsequent single-site laparoscopic surgery involving right hemicolectomy and paracolic lymph node dissection.Intra-abdominal dissemination to the mesocolon was confirmed during surgery.Histopathologically,the transverse colon cancer was confirmed to be moderately differentiated tubular adenocarcinoma.We suspect that SMJN may occur via a hematogenous pathway.Although chemotherapy for colon cancer and thoracoscopic surgery for the primary lung cancer were scheduled,the patient and her family desired home hospice.Seven months after surgery,she died of rapidly growing lung cancer. | Tomohide Hori Noriyuki Okada Masaya Nakauchi Shuji Hiramoto Ayako Kikuchi-Mizota Masahisa Kyogoku Fumitaka Oike Hidemitsu Sugimoto Junya Tanaka Yoshiki Morikami Kaori Shigemoto Toyotsugu Ota Masanobu Kaneko Masato Nakatsuji Shunji Okae Takahiro Tanaka Daigo Gunji Akira Yoshioka | 2013 | World Journal of Gastrointestinal Surgery2013，5，10： | 2 |
| 6 | B‐cell surface marker analysis for improvement of rituximab prophylaxis in ABO‐incompatible adult living donor liver transplantation显示文摘 | Hiroto Egawa Katsuyuki Ohmori Hironori Haga Hiroaki Tsuji Kimiko Yurugi Aya Miyagawa‐Hayashino Fumitaka Oike Akinari Fukuda Jun Yoshizawa Yasutsugu Takada Koichi Tanaka Taira Maekawa Kazue Ozawa Shinji Uemoto | 2007 | Liver Transpl2007，，4： | 1 |
| 7 | Anatomical variations and surgical strategies in right lobe living donor liver transplantation: lessons from 120 cases1显示文摘 | Taro Nakamura Koichi Tanaka Tetsuya Kiuchi Mureo Kasahara Fumitaka Oike Mikiko Ueda Satoshi Kaihara Hiroto Egawa Ilgin Ozden Nobuaki Kobayashi Shinji Uemoto | 2002 | Transplantation2002，，12： | 1 |
| 8 | Expansion of selection criteria for patients with hepatocellular carcinoma in living donor liver transplantation显示文摘 | Takashi Ito Yasutsugu Takada Mikiko Ueda Hironori Haga Yoji Maetani Fumitaka Oike Kohei Ogawa Seisuke Sakamoto Yasuhiro Ogura Hiroto Egawa Koichi Tanaka Shinji Uemoto | 2007 | Liver Transpl2007，，12： | 1 |
| 9 | Biliary Reconstruction in Right Lobe Living-Donor Liver Transplantation: Comparison of Different Techniques in 321 Recipients显示文摘 | Mureo Kasahara Hiroto Egawa Yasutsugu Takada Fumitaka Oike Seisuke Sakamoto Tetsuya Kiuchi Syujiro Yazumi Toshiya Shibata Koichi Tanaka | 2006 | Annals of Surgery2006，，4： | 1 |
| 10 | Thrombotic microangiopathy-like disorder after living-donor liver transplantation:A single-center experience in Japan显示文摘AIM:To investigate thrombotic microangiopathy (TMA)in liver transplantion,because TMA is an infrequent but life-threatening complication in the transplantation field. METHODS:A total of 206 patients who underwent living-donor liver transplantation (LDLT) were evaluated,and the TMA-like disorder (TMALD) occurred in seven recipients. RESULTS:These TMALD recipients showed poor outcomes in comparison with other 199 recipients. Although two TMALD recipients successfully recovered,the other five recipients finally died despite intensive treatments including repeated plasma exchange (PE) and re-transplantation. Histopathological analysis of liver biopsies after LDLT revealed obvious differences according to the outcomes. Qualitative analysis of antibodies against a disintegrin-like domain and metalloproteinase with thrombospondin type 1 motifs (ADAMTS-13) were negative in all patients. The fragmentation of red cells,the microhemorrhagic macules and the platelet counts were early markers for the suspicion of TMALD after LDLT. Although the absolute values of von Willebrand factor (vWF) and ADAMTS-13 did not necessarily reflect TMALD,the vWF/ADAMTS-13 ratio had a clear diagnostic value in all cases. The establishment of adequate treatments for TMALD,such as PE for ADAMTS-13 replenishment or treatments against inhibitory antibodies,must be decided according to each case. CONCLUSION:The optimal induction of adequate therapies based on early recognition of TMALD by the reliable markers may confer a large advantage for TMALD after LDLT. | Tomohide Hori Toshimi Kaido Fumitaka Oike Yasuhiro Ogura Kohei Ogawa Yukihide Yonekawa Koichiro Hata Yoshiya Kawaguchi Mikiko Ueda Akira Mori Yasutsugu Takada Hiroto Egawa Atsushi Yoshizawa Shinji Uemoto Hajime Segawa Kimiko Yurugi Takuma Kato Kanako Saito Linan Wan Mie Torii Feng Chen Ann-Marie T Baine Lindsay B Gardner | 2011 | World Journal of Gastroenterology2011，17，14： | 1 |
| 11 | Simplified technique of orthotopic liver transplantation in pigs 显示文摘 | Oike Fumitaka Uryuhara | 2001 | Transplantation2001，71，2： | 1 |
| 12 | Does a positive lymphocyte cross-match contraindicate living-donor liver transplantation?显示文摘 | Tomohide Hori Shinji Uemoto Yasutsugu Takada Fumitaka Oike Yasuhiro Ogura Kohei Ogawa Aya Miyagawa-Hayashino Kimiko Yurugi Justin H. Nguyen Yukinobu Hori Feng Chen Hiroto Egawa | 2010 | Surgery2010，，6： | 1 |
| 13 | Surgery-Related Morbidity in Living Donors for Liver Transplantation显示文摘 | Taku Iida Yasuhiro Ogura Fumitaka Oike Etsuro Hatano Toshimi Kaido Hiroto Egawa Yasutsugu Takada Shinji Uemoto | 2010 | Transplantation2010，，10： | 1 |
| 14 | Living-donor liver transplantation with monosegments显示文摘 | Mureo Kasahara Satoshi Kaihara Fumitaka Oike Takashi Ito Yasuhiro Fujimoto Yasuhiro Ogura Kohei Ogawa Mikiko Ueda Mohamed Rela Nigel D Heaton Koichi Tanaka | 2003 | Transplantation2003，，4： | 1 |
| 15 | Monosegmental living-donor liver transplantation for infantile hepatic hemangioendothelioma显示文摘 | Mureo Kasahara Tetsuya Kiuchi Hironori Haga Shinji Uemoto Kenji Uryuhara Yasuhiro Fujimoto Yasuhiro Ogura Fumitaka Oike Akiko Yokoi Satoshi Kaihara Hiroto Egawa Koichi Tanaka | 2003 | Journal of Pediatric Surgery2003，，7： | 1 |
| 16 | Impact of MDR1 and CYP3A5 on the oral clearance of tacrolimus and tacrolimus-related renal dysfunction in adult living-donor liver transplant patients显示文摘 | Masahide Fukudo Ikuko Yano Atsushi Yoshimura Satohiro Masuda Miwa Uesugi Keiko Hosohata Toshiya Katsura Yasuhiro Ogura Fumitaka Oike Yasutsugu Takada Shinji Uemoto Ken-ichi Inui | 2008 | Pharmacogenetics and Genomics2008，，5： | 1 |
| 17 | Effect of intestinal CYP3A5 on postoperative tacrolimus trough levels in living-donor liver transplant recipients显示文摘 | Miwa Uesugi Satohiro Masuda Toshiya Katsura Fumitaka Oike Yasutsugu Takada Ken-ichi Inui | 2006 | Pharmacogenetics and Genomics2006，，2： | 1 |
| 18 | Changes in portal venous pressure in the early phase after living donor liver transplantation: pathogenesis and clinical implications1,2显示文摘 | Takashi Ito Tetsuya Kiuchi Hidekazu Yamamoto Fumitaka Oike Yasuhiro Ogura Yasuhiro Fujimoto Kazuhiro Hirohashi and Koichi Tanaka | 2003 | Transplantation2003，，8： | 1 |
| 19 | Small-for-size graft in living donor liver transplantation: How far should we go?显示文摘 | Tetsuya Kiuchi Koichi Tanaka Takashi Ito Fumitaka Oike Yasuhiro Ogura Yasuhiro Fujimoto Kohei Ogawa | 2003 | Liver Transplantation2003，，9： | 1 |
| 20 | Changes in portal venous pressure in the early phase after living donor liver transplantation: pathogenesis and clinical implications1,2显示文摘 | Takashi Ito Tetsuya Kiuchi Hidekazu Yamamoto Fumitaka Oike Yasuhiro Ogura Yasuhiro Fujimoto Kazuhiro Hirohashi and Koichi Tanaka | 2003 | Transplantation2003，，8： | 1 |
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