|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Colonic Mucosal Immune Activity in Irritable Bowel Syndrome: Comparison with Healthy Controls and Patients with Ulcerative Colitis显示文摘 | Ji Yong Ahn Kyung Hun Lee Chang Hwan Choi Ju Wan Kim Hyun Woong Lee Jeong Wook Kim Mi Kyung Kim Gui Young Kwon Seungbong Han Seong-Eun Kim Sung Min Kim Sae Kyung Chang | 2014 | Digestive Diseases and Sciences2014，，5： | 3 |
| 2 | 每日一次与按需使用乌地那非对治疗2型糖尿病患者勃起功能障碍的有效性和安全性比较显示文摘通过一项为期12周的多中心、随机、开放、平行组试验,比较每日一次与按需使用乌地那非对治疗2型糖尿病患者勃起功能障碍的有效性和安全性。按需服用乌地那非200mg能够改善勃起功能障碍的161名患者,被随机分为200mg按需治疗组(n=80)和50mg每日一次组仰=81),两组分别接受相应治疗8周,8周后停药并随访4周,这些患者均通过性活动日志中Q2(插入成功率)和Q3(性交中保持勃起至完成性交的成功率)进行评估。主要的疗效指标是国际勃起功能问卷.勃起功能分级(IIEF.EFD)评分的变化。次要的疗效指标包括性活动日志02、Q3,国际勃起功能问卷的Q3、Q4及其他部分,全球评估问卷,以及正常率(EFD_〉26)的变化。我们也对血管内皮细胞标志物进行了检测。经过8周的治疗,两组的IIEF.EFD评分都得到改善fP〈O.0001),且两组之间没有显著的统计学差异。但这种改善并没有维持到无治疗随访期之后。次要的疗效指标也有类似的结果。在血管内皮标志物方面,两组之间无显著差异。患者对每日一次乌地那非具有更好的耐受性,且两组之间药物不良反应以及不良事件方面无显著性差异。其中脸红和头痛是最常见的不良反应。这两种方案都能改善糖尿病患者的勃起功能障碍,且均有良好的患者耐受性。乌地那非每日给药对糖尿病患者勃起功能障碍的治疗作用值得进一步研究。 | Soon Hyun Park Sung Woo Park Bong Yun Cha Ie Byung Park Kyung Wan Min Yeon Ah Sung Tae Hwa Kim Jae Min Lee Kang Seo Park | 2015 | Asian Journal of Andrology2015，17，1： | 2 |
| 3 | MSC-based VEGF gene therapy in rat myocardial infarction model using facial amphipathic bile acid-conjugated polyethyleneimine显示文摘 | Hyung-Ho Moon Min Kyung Joo Hyejung Mok Minhyung Lee Ki-Chul Hwang Sung Wan Kim Ji Hoon Jeong Donghoon Choi Sun Hwa Kim | 2014 | Biomaterials2014，，5： | 2 |
| 4 | Cardiovascular risk assessment with vascular function,carotid atherosclerosis and the UKPDS risk engine in Korean patients with newly diagnosed type 2diabetes显示文摘 | Choon Sik Kyung Wan Min Seung Yup Lee | 2011 | Diabet Metab J2011，35，： | 1 |
| 5 | The prevalence and risk factors of vertebral fractures in Korea显示文摘 | Chan Soo Shin Min Joo Kim Sang Mi Shim Jin Taek Kim Sung Hoon Yu Bo Kyung Koo Hwa Young Cho Hyung Jin Choi Sun Wook Cho Sang Wan Kim Seong Yeon Kim Seung-O Yang Nam H. Cho | 2012 | Journal of Bone and Mineral Metabolism2012，，： | 1 |
| 6 | Transporter-mediated bile acid uptake causes Ca 2+ -dependent cell death in rat pancreatic acinar cells显示文摘 | Joo Young Kim Kyung Hwan Kim Jin Ah Lee Wan Namkung An–Qiang Sun Meena Ananthanarayanan Frederick J. Suchy Dong Min Shin Shmuel Muallem Min Goo Lee | 2002 | Gastroenterology2002，，7： | 1 |
| 7 | Exploring ideal operative time for best outcomes in gastric cancer surgery:A multi-institutional study based on KLASS-07 database显示文摘Objective:While a rushed operation can omit essential procedures,prolonged operative time results in higher morbidity.Nevertheless,the optimal operative time range remains uncertain.This study aimed to estimate the ideal operative time range and evaluate its applicability in laparoscopic cancer surgery.Methods:A prospectively collected multicenter database of 397 patients who underwent laparoscopic distal gastrectomy were retrospectively reviewed.The ideal operative time range was statistically calculated by separately analyzing the operative time of uneventful surgeries.Finally,intraoperative and postoperative outcomes were compared among the shorter,ideal,and longer operative time groups.Results:The statistically calculated ideal operative time was 135.4-165.4 min.The longer operative time(LOT)group had a lower rate of uneventful,perfect surgery than the ideal or shorter operative time(IOT/SOT)group(2.8%vs.8.8%and 2.2%vs.13.4%,all P<0.05).Longer operative time increased bleeding,postoperative morbidities,and delayed diet and discharge(all P<0.05).Particularly,an uneventful,perfect surgery could not be achieved when the operative time exceeded 240 min.Regardless of ideal time range,SOT group achieved the highest percentage of uneventful surgery(13.4%),which was possible by surgeon's ability to retrieve a higher number of lymph nodes and perform≥150 gastrectomies annually.Conclusions:Operative time longer than the ideal time range(especially≥240 min)should be avoided.If the essential operative procedure were faithfully conducted without compromising oncological safety,an operative time shorter than the ideal range leaded to a better prognosis.Efforts to minimize operative time should be attempted with sufficient surgical experience. | Shin-Hoo Park Ye-Rim Shin Hoon Hur Chang Min Lee Jae Seok Min Seung Wan Ryu Hyun Dong Chae Oh Jeong Chang-In Choi Kyo-Young Song Ho Goon Kim Ye Seob Jee Kwang Hee Kim Jeong Goo Kim Kyung Sook Yang Hua Huang Sungsoo Park | 2023 | Chinese Journal of Cancer Research2023，35，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员