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| 1 | OsVPS9A Functions Cooperatively with OsRAB5A to Regulate Post-Golgi Dense Vesicle-Mediated Storage Protein Trafficking to the Protein Storage Vacuole in Rice Endosperm Cells显示文摘在米饭内乳房间, glutelins 作为 proglutelins 在不平的 endoplasmic 蜂窝胃上被综合并且被排序到称为蛋白质身体 II (PBII ) 的 theprotein 存储液泡(PSV ) ,在他们被变换成成熟形式的地方。稠密的泡(DV ) 调停了在大米种子的 proglutelins 的 trafficking 被建议了,但是这个过程的 post-Golgi 控制是 largelyunknown。DV 是否能与 PSV 直接熔化,是争论的另一件事。在这研究,我们建议规章的 mechanismunderlying 调停 DV, post-Golgi proglutelin trafficking 到 PBII (PSV ) 。gpa2, OsVPS9A 的 loss-of-function 异种,编码 OsRAB5A 的 GEF,积累了 uncleaved proglutelins。Proglutelins 对到沿着在 DV 形式的房间墙的 apoplast 的 paramural bodiesand 指向 mis,它在 PBII 尺寸导致了伴随物减小。Previouslyreported gpa1,在 OsRab5a 变异,有类似的显型,当时两倍异种加重了的 gpa1gpa2 条件。另外, OsVPS9A 在 vitro 并且在 vivo 与 OsRAB5A 交往了。我们断定 OsVPS9A 和 OsRAB5A 可以一起工作并且在调停 DV 的 post-Golgi proglutelintrafficking 起一个规章的作用到 PBII (PSV ) 。DV 可能直接熔化到 PBII (PSV ) 交付货物的证据也是 presented.Key 词: | Feng Liu Yulong Ren Yihua Wang Cheng Peng Kunneng Zhou Jia Lv Xiuping Guo Xin Zhang Jianmin wan Yiqun Bao | 2013 | Molecular Plant2013，6，6： | 16 |
| 2 | Dental remineralization via poly(amido amine) and restorative materials containing calcium phosphate nanoparticles显示文摘Tooth decay is prevalent,and secondary caries causes restoration failures,both of which are related to demineralization.There is an urgent need to develop new therapeutic materials with remineralization functions.This article represents the first review on the cutting edge research of poly(amido amine)(PAMAM) in combination with nanoparticles of amorphous calcium phosphate (NACP).PAMAM was excellent nucleation template,and could absorb calcium (Ca) and phosphate (P) ions via its functional groups to activate remineralization.NACP composite and adhesive showed acid-neutralization and Ca and P ion release capabilities.PAMAM +NACP together showed synergistic effects and produced triple benefits: excellent nucleation templates,superior acidneutralization,and ions release.Therefore,the PAMAM+NACP strategy possessed much greater remineralization capacity than using PAMAM or NACP alone.PAMAM+NACP achieved dentin remineralization even in an acidic solution without any initial Ca and P ions.Besides,the long-term remineralization capability of PAMAM+NACP was established.After prolonged fluid challenge,the immersed PAMAM with the recharged NACP still induced effective dentin mineral regeneration.Furthermore,the hardness of predemineralized dentin was increased back to that of healthy dentin,indicating a complete remineralization.Therefore,the novel PAMAM+NACP approach is promising to provide long-term therapeutic effects including tooth remineralization,hardness increase,and caries-inhibition capabilities. | Kunneng Liang Suping Wang Siying Tao Shimeng Xiao Han Zhou Ping Wang Lei Cheng Xuedong Zhou Michael D.Weir Thomas W.Oates Jiyao Li Hockin H.K.Xu | 2019 | International Journal of Oral Science2019，11，3： | 3 |
| 3 | Overexpression of OsZHD1 , a zinc finger homeodomain class homeobox transcription factor, induces abaxially curled and drooping leaf in rice显示文摘 | Yang Xu Yihua Wang Qizhang Long Jiexue Huang Yunlong Wang Kunneng Zhou Ming Zheng Juan Sun Hong Chen Saihua Chen Ling Jiang Chunming Wang Jianmin Wan | 2014 | Planta2014，，4： | 1 |
| 4 | Regeneration of biomimetic hydroxyapatite on etched human enamel by anionic PAMAM template in vitro显示文摘 | Liang C Kunneng L Jian SL et el | 2013 | Arch Oral Biol2013，58，8： | 1 |
| 5 | Two-in-one strategy:a remineralizing and anti-adhesive coating against demineralized enamel显示文摘Tooth enamel is prone to be attacked by injurious factors,leading to a de/remineralization imbalance.To repair demineralized enamel and prevent pulp inflammation caused by biofilm accumulation,measures are needed to promote remineralization and inhibit bacterial adhesion on the tooth surface.An innovative material,poly(aspartic acid)-polyethylene glycol(PASP-PEG),was designed and synthesized to construct a mineralizing and anti-adhesive surface that could be applied to repair demineralized enamel.A cytotoxicity assay revealed the low cytotoxicity of synthesized PASP-PEG.Adsorption results demonstrated that PASPPEG possesses a high binding affinity to the hydroxyapatite(HA)/tooth surface.In vitro experiments and scanning electron microscopy(SEM)demonstrated a strong capacity of PASP-PEG to induce in situ remineralization and direct the oriented growth of apatite nanocrystals.Energy dispersive X-ray spectroscopy(EDS),X-ray diffraction analysis(XRD)and Vickers hardness tests demonstrated that minerals induced by PASP-PEG were consistent with healthy enamel in Ca/P ratio,crystal form and surface micro-hardness.Contact angle tests and bacterial adhesion experiments demonstrated that PASP-PEG yielded a strong antiadhesive effect.In summary,PASP-PEG could achieve dual effects for enamel repair and anti-adhesion of bacteria,thereby widening its application in enamel repair. | Ailin Hou Jun Luo Min Zhang Jianshu Li Wenlin Chu Kunneng Liang Jiaojiao Yang Jiyao Li | 2020 | International Journal of Oral Science2020，12，3： | 0 |
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