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| 1 | Corrosion behavior of Mg-Y alloy in NaCl aqueous solution | Xin Zhang a,b,c,Kui Zhang a,Xia Deng a,Hongwei Li b,c,Yongjun Li a,Minglong Ma a,Ning Li b,c,Yanlong Wang b,c a State Key Laboratory for Fabrication and Processing of Nonferrous Metals,Beijing General Research Institute for Nonferrous Metals,Beijing 100088,China b Beijing Engineering Research Center for Advanced Manufacturing and Evaluation of Special Vehicle Parts,Beijing 100072,China c Center of Technology,Beijing North Vehicle Group Corporation,Beijing 100072,China | 2012 | Progress in Natural Science:Materials International2012,22,2: | 7 |
| 2 | Redox regulation in tumor cell epithelial-mesenchymal transition:molecular basis and therapeutic strategy显示文摘Epithelial–mesenchymal transition(EMT)is recognized as a driving force of cancer cell metastasis and drug resistance,two leading causes of cancer recurrence and cancer-related death.It is,therefore,logical in cancer therapy to target the EMT switch to prevent such cancer metastasis and recurrence.Previous reports have indicated that growth factors(such as epidermal growth factor and fibroblast growth factor)and cytokines(such as the transforming growth factor beta(TGF-β)family)are major stimulators of EMT.However,the mechanisms underlying EMT initiation and progression remain unclear.Recently,emerging evidence has suggested that reactive oxygen species(ROS),important cellular secondary messengers involved in diverse biological events in cancer cells,play essential roles in the EMT process in cancer cells by regulating extracellular matrix(ECM)remodeling,cytoskeleton remodeling,cell–cell junctions,and cell mobility.Thus,targeting EMT by manipulating the intracellular redox status may hold promise for cancer therapy.Herein,we will address recent advances in redox biology involved in the EMT process in cancer cells,which will contribute to the development of novel therapeutic strategies by targeting redox-regulated EMT for cancer treatment. | Jingwen Jiang Kui Wang Yan Chen Haining Chen Edouard C Nice Canhua Huang | 2017 | Signal Transduction and Targeted Therapy2017,2,1: | 5 |
| 3 | Choracteristic of the prevalence of Juave in apparently healthy Chinese adults显示文摘 | Kui C Congxin H Xi W | 2008 | Arch Med Res2008,39,2: | 1 |
| 4 | Normal serumam in transferase levels and the metabolic syndrome: Korean National Health and Nutrition Ex- amination Survey显示文摘 | HYEON C K KUI S C | 2006 | Yonsei Med J2006,47,4: | 1 |
| 5 | MicroRNA-mediated repression of rolled leafl specifies maize leaf polarity 显示文摘 | Juarez M T Kui J S Thomas J Heller B A Timrnermans M C | 2004 | Nature2004,428,: | 1 |
| 6 | Improving the belief-propagation convergence of irregular LDPC codes using column-weight based scheduling显示文摘 | ASLAM C A GUAN Yongliang and CAI Kui | 2015 | IEEE Communi- cations Letters2015,19,8: | 1 |
| 7 | Synthesis,biological evaluation and molecular docking studies of amidecoupled benzoic nitrogen mustard derivatives as potential antitumor agents显示文摘 | Zheng Q Z Zhang F Kui C | 2010 | Bioorg Med Chem2010,18,: | 1 |
| 8 | Platinum(Ⅱ) Complexes with π-Conjugated, Naphthyl-substituted, Cyclometalated Ligands (RC^N^N) : Structures and Photo- and Electroluminescence 显示文摘 | Kui S C F Sham I H T Cheung C C C | 2007 | Chem Eur J2007,13,: | 1 |
| 9 | Synthesis, Photophysical and Electrophosphoreseent Properties of Fluorene-based Platinum(Ⅱ) Complexes显示文摘 | Yuen M Y Kui S C F Low K H | 2010 | Chem Eur J2010,16,14: | 1 |
| 10 | Self-assembly of a cyclic metalladecapyridine from the reaction of 2,6 bis ( bis ( 2-pyridyl ) methoxymethane ) pyridine with silver(I)显示文摘 | HUANG J S XIE J KUI S C F | 2008 | Inorganic Chemistry2008,47,13: | 1 |
| 11 | Improved the Belief-Propagation Convergence of Irregular LD- PC Codes Using Column-Weight Based Scheduling 显示文摘 | ASIAM C A YONG Liangguan CAI Kui | 2015 | IEEE Communication Letters2015,19,8: | 1 |
| 12 | Neutron and X-ray diffraction and spectroscopic investigations of intramolecular (C-H center dot center dot center dot F-C) contacts in post- metallocene polyolefin catalysts: modeling weak attractive poly- mer-ligand interactions显示文摘 | Chan M C W Kui S C F Cole J M | 2006 | Chem Eur J2006,12,9: | 1 |
| 13 | Obsercation of intramolecnlar C-H center dot center dot center dot F-C contacts in non- metallocene polyolefin catalysts: model for weak attractive interactions between polymer chain and noninnocent ligand 显示文摘 | Kui S C F Zhu N Chan M C W | 2003 | Angew Chem Int Ed2003,42,14: | 1 |
| 14 | Efficient white organic light-emitting devices based on phosphorescent plati- num (Ⅱ)/fluorescent dual-emitting layers 显示文摘 | Yan B P Cheung C C C Kui S C F | 2007 | Advanced Materials2007,19,21: | 1 |
| 15 | Thermoluminescence properties of double potassium yttrium fluorides singly doped with Ce3 + , Tb3 , Dy3 and Tm3 in response to and -irradiation 显示文摘 | Kui H W Lo D Tsang Y C | 2006 | Journal of Luminescence2006,117,: | 1 |
| 16 | Photovohaic mechanisms in ferroelectric thin films with the effects of the electrodes and interfaces 显示文摘 | Meng Q Kui Y Liang Y C | 2009 | Applied Physics Letters2009,95,2: | 1 |
| 17 | Thermal decom- position of wood and cellulosein in the presence of solvent va- pors显示文摘 | JAKAB E LIU Kui MEUZELAAR H L C | 1996 | Industrial and Engineering Chemistry Research1996,36,6: | 1 |
| 18 | The long-run behaviour of the real exchange rate:evidence from colonial Pennsylvania显示文摘 | TAUFIQ C KUI B L | 2001 | Economics Letters2001,74,: | 1 |
| 19 | Meplazumab in hospitalized adults with severe COVID-19(DEFLECT):a multicenter,seamless phase 2/3,randomized,third-party double-blind clinical trial显示文摘Meplazumab,a humanized CD147 antibody,has shown favourable safety and efficacy in our previous clinical studies.In DEFLECT(NCT04586153),167 patients with severe COVID-19 were enroled and randomized to receive three dosages of meplazumab and a placebo.Meplazumab at 0.12 mg/kg,compared to the placebo group,showed clinical benefits in significantly reducing mortality by 83.6%(2.4%vs.14.6%,p=0.0150),increasing the proportion of patients alive and discharged without supplemental oxygen(82.9%vs.70.7%,p=0.0337)and increasing the proportion of patients who achieved sustained clinical improvement(41.5%vs.31.7%).The response rate in the 0.2 mg/kg group was relatively increased by 16.0%compared with the placebo group(53.7%vs.46.3%).Meplazumab also reduced the viral loads and multiple cytokine levels.Compare with the placebo group,the 0.3 mg/kg significantly increased the virus negative rate by 40.6%(p=0.0363)and reduced IL-8 level(p=0.0460);the 0.2 mg/kg increased the negative conversion rate by 36.9%,and reduced IL-4(p=0.0365)and IL-8 levels(p=0.0484).In this study,the adverse events occurred at a comparable rate across the four groups,with no unexpected safety findings observed.In conclusion,meplazumab promoted COVID-19 convalescence and reduced mortality,viral load,and cytokine levels in severe COVID-19 population with good safety profile. | Huijie Bian Liang Chen Zhao-Hui Zheng Xiu-Xuan Sun Jie-Jie Geng Ruo Chen Ke Wang Xu Yang Shi-Rui Chen Si-Yu Chen Rong-Hua Xie Kui Zhang Jin-Lin Miao Jun-Feng Jia Hao Tang Shuang-Shuang Liu Hong-Wei Shi Yong Yang Xiao-Chun Chen Vinay Malhotra Nosheen Nasir Iffat Khanum Faisal Mahmood Saeed Hamid Claudio Marcel Berdun Stadnik Kengi Itinose Caroline Cândida Carvalho de Oliveira Cesar Dusilek Lucas Rivabem Adilson Joaquim Westheimer Cavalcante Suzara Souto Lopes Wladmir Faustino Saporito Fábio JoséConcilio Fucci Jesus Abraham Simon-Campos Ling Wang Lin-Na Liu Qing-Yi Wang Ding Wei Zheng Zhang Zhi-Nan Chen Ping Zhu | 2023 | Signal Transduction and Targeted Therapy2023,8,2: | 1 |
| 20 | Evaluation of the air bronchogram sign on CT in solitary pulmonary lesions显示文摘 | Kui M Templeton P A White C S | 1996 | Comput Assist Tomogr1996,20,6: | 1 |