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| 1 | Antibacterial activity of honey against clinical isolates of Escherichia coli,Pseudomonas aeruginosa and Salmonella enterica serovar Typhi显示文摘Objective:To ascertain the potential antibacterial activity of honey against clinical isolates of Escherichia coli(E.coli),Pseudomonas aeruginosa(P.aeruginosa) and Salmonella enterica serovar Typhi(S.enterica serovar Typhi) by in vitro methods.Methods:The partial inhibitory concentration(PIC),minimum inhibitory concentration(MIC) and minimum bactericidal concentration(MBC) values of the autoclaved honey(extracted from Apis indica hive by indigenous method) were determined for S.enterica serovar Typhi(n=8:from blood cultute), E.coli(n=5:from urine culture) and P.aeruginosa(n=5:from pus culture) isolates by in vitro methods.Results:The PICs of the honey tested for the isolates ranged 0.50%-1.25%(v/v) for S. enterica serovar Typhi,0.75%-1.50%(v/v) for E.coli and 1.00%-1.25%(v/v) for P.aeruginosa, while the MICs ranged 1.75%-3.00%(v/v),3.00%-3.50%(v/v) and 3.50%(v/v),respectively.The P.aeruginosa and E.coli isolates had MBC value of 4.00%(v/v):the S.enterica serovar Typhi showed MBCs in between 3.00%and 3.50%(v/v).The bactericidal activity of honey was achieved at concentration 3.00%(v/v) for S.enterica serovar Typhi and E.coli,and at 3.50%(v/v) for P. aeruginosa.Conclusions:The excellent antibacterial activity of honey against clinical bacterial isolates indicates the usefulness of honey in clinical practice against bacterial infection. | Shyamapada Mandal Manisha DebMandal Nishith Kumar Pal Krishnendu Saha | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，12： | 8 |
| 2 | Synergistic anti - Staphylococcus aureus activity of amoxicillin in combination with Emblica officinalis and Nymphae odorata extracts显示文摘Objective:To evaluate the antibacterial activity of Emblica officinalis Gaertn(E.officinalis: Family:Euphorbiaceae) seed and Nymphae odorala Aiton(N.odorala:Family:Nymphaeaceae) stamen extracts,alone and in combination,and in combination with amoxicillin(Ax) against Staphylococcus aureus(S.aureus).Methods:Antibacterial activity of ethanolic extracts of amla,E.officinalis,seed(AMS:500μg) and sapla,N.odorala,stamen(SAP:500 p g) for 12 methicillin-resistant S.aureus(MRSA) isolates was determined following agar diffusion:in order to assess the combined antibacterial activity,AMS(250μg) plus SAP(250μg) were considered.The Ax(10μg) activity alone and in combination with AMS(250μg),and SAP(250μg) was determined by disk diffusion.The zone diameters of inhibition(ZDIs) for the agents were recorded,and growth inhibitory indices(GIIs) were calculated.Results:The MRSA isolates (n=12) had AMS(500μg) and SAP(500μg) ZDIs of 12-19 mm and 21-24 mm,respectively.The ZDIs(range 24-27 mm) increased by 3-4 mm due to combined action of AMS(250μg) and SAP(250μg) indicating synergy between extracts for MRSA(GII 0.634-0.742).The MRSA isolates were resistant to Ax(ZDI:8-11 mm),which in combination with AMS and SAP had synergistic effect,both due to increased ZDI[mean±SD=(3.5±0.577) mm]and GII(0.631-0.894).Conclusions:The data suggest that the plants,E.officinalis and N.odorala alone or in combination,are promising in the development of phytomedicines,which may be used,alone or in combination with the antibiotic. Ax,against MRSA infection. | Shyamapada Mandal Manisha DebMandal Nishith Kumar Pal Krishnendu Saha | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，9： | 6 |
| 3 | Risk Behaviors of Homeless Men in India: A Potential Bridge Population for HIV Infection显示文摘 | Arunansu Talukdar Krishnendu Roy Indrajit Saha Jayashree Mitra Roger Detels | 2008 | AIDS and Behavior2008，，4： | 1 |
| 4 | Apoptogenic effects of Tricholoma giganteum on Ehrlich’s ascites carcinoma cell显示文摘 | Soumya Chatterjee Gunjan Biswas Swarnendu Chandra Goutam Kumar Saha Krishnendu Acharya | 2013 | Bioprocess and Biosystems Engineering2013，，1： | 1 |
| 5 | Antioxidant and nitric oxide synthase activation properties of water soluble polysaccharides from Pleurotus florida显示文摘 | Saha Subarna Khatua Somanjana Paloi Soumitra Acharya Krishnendu | 2013 | International Journal of Green Pharmacy2013，7，3： | 1 |
| 6 | Surfactant - induced fluo- rescent sensor activity enhan- cement of tryptophan at various pH 显示文摘 | Prasun Bandyopadhyay Krishnendu Saha | 2008 | Chemical Physics Letters2008，457，13： | 1 |
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