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| 1 | Tumor infiltrating lymphocytes in triple negative breast cancer receiving neoadjuvant chemotherapy显示文摘AIM To determine influence of neoadjuvant-chemotherapy(NAC) over tumor-infiltrating-lymphocytes(TIL) intriple-negative-breast-cancer(TNBC).METHODS TILs were evaluated in 98 TNBC cases who came to Instituto Nacional de Enfermedades Neoplasicas from 2005 to 2010. Immunohistochemistry staining for CD3, CD4, CD8 and FOXP3 was performed in tissue microarrays(TMA) sections. Evaluation of H/E in full-face and immunohistochemistry in TMA sections was performed in pre and post-NAC samples. STATA software was used and P value < 0.05 was considered statistically significant. RESULTS Higher TIL evaluated in full-face sections from pre-NAC tumors was associated to pathologic-complete-response(pCR)(P = 0.0251) and outcome(P = 0.0334). TIL evaluated in TMA sections showed low level of agreement with full-face sections(ICC = 0.017-0.20) and was not associated to pCR or outcome. TIL in post-NAC samples were not associated to response or outcome. PostNAC lesions with pC R had similar TIL levels than those without pCR(P = 0.6331). NAC produced a TIL decrease in full-face sections(P < 0.0001). Percentage of TIL subpopulations was correlated with their absolute counts. Higher counts of CD3, CD4, CD8 and FOXP3 in pre-NAC samples had longer disease-free-survival(DFS). Higher counts of CD3 in pre-NAC samples had longer overallsurvival. Higher ratio of CD8/CD4 counts in pre-NAC was associated with pCR. Higher ratio of CD4/FOXP3 counts in pre-NAC was associated with longer DFS. Higher counts of CD4 in post-NAC samples were associated with pCR.CONCLUSION TIL in pre-NAC full-face sections in TNBC are correlated to longer survival. TIL in full-face differ from TMA sections, absolute count and percentage analysis of TIL subpopulation closely related. | Carlos A Castaneda Elizabeth Mittendorf Sandro Casavilca Yun Wu Miluska Castillo Patricia Arboleda Teresa Nunez Henry Guerra Carlos Barrionuevo Ketty Dolores-Cerna Carolina Belmar-Lopez Julio Abugattas Gabriela Calderon Miguel De La Cruz Manuel Cotrina Jorge Dunstan Henry L Gomez Tatiana Vidaurre | 2016 | World Journal of Clinical Oncology2016，7，5： | 6 |
| 2 | pyruvic acid peels for the treatment of photoaging 显示文摘 | Ilaarza Ghersetich Benedetta Brazzini Ketty Peris | 2004 | Dermator2004，30，： | 1 |
| 3 | Novel aspects of grape berry ripening and post-harvest withering revealed by untargeted LC-ESI-MS metabolomics analysis显示文摘 | Toffali Ketti Zamboni Anita Anesi Andrea | 2011 | Metabolomics2011，7，3： | 1 |
| 4 | Hypertrophic Cardiomyopathy: Distribution of Disease Genes, Spectrum of Mutations, and Implications for a Molecular Diagnosis Strategy显示文摘 | Pascale Richard Philippe Charron Lucie Carrier Céline Ledeuil Theary Cheav Claire Pichereau Abdelaziz Benaiche Richard Isnard Olivier Dubourg Marc Burban Jean-Pierre Gueffet Alain Millaire Michel Desnos Ketty Schwartz Bernard Hainque Michel Komajda | 2003 | Circulation: Journal of the American Heart Association2003，，17： | 1 |
| 5 | Diagnosis and treatment of melanoma: European consensus-based interdisciplinary guideline显示文摘 | Claus Garbe Ketty Peris Axel Hauschild Philippe Saiag Mark Middleton Alain Spatz Jean-Jacques Grob Josep Malvehy Julia Newton-Bishop Alexander Stratigos Hubert Pehamberger Alexander Eggermont | 2009 | European Journal of Cancer2009，，2： | 1 |
| 6 | Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction显示文摘 | Philippe Menasché Albert A Hagège Jean-Thomas Vilquin Michel Desnos Eric Abergel Bruno Pouzet Alain Bel Sorin Sarateanu Marcio Scorsin Ketty Schwartz Patrick Bruneval Marc Benbunan Jean-Pierre Marolleau Denis Duboc | 2003 | Journal of the American College of Cardiology2003，，7： | 1 |
| 7 | Schwann cell dedifferentiation is independent of mitogenie signaling and uncoupled to proliferation role of cAMP and JNK in the maintenance of the differentiation state显示文摘 | Paula VM Jennifer S Ketty B | 2010 | J Biol Chem2010，285，31： | 1 |
| 8 | Sex hormone-binding globulin expression in the endometria of women with polycystic ovary syndrome 显示文摘 | Manuel M Ketty B Susana Q | 2007 | Fertil Steril2007，87，： | 1 |
| 9 | Gastric cancer with high-level microsatellite instability: target gene mutations, clinicopathologic features, and long-term survival显示文摘 | Mario Falchetti Calogero Saieva Ramona Lupi Giovanna Masala Piera Rizzolo Ines Zanna Ketty Ceccarelli Francesco Sera Renato Mariani-Costantini Gabriella Nesi Domenico Palli Laura Ottini | 2008 | Human Pathology2008，，6： | 1 |
| 10 | RHCE phenotypes in black individuals of Afro-Caribbean origin:identi?cation and transfusion safety显示文摘 | FRANCE NP KETTY LEE PY PENNEC R | 2002 | Blood2002，100，： | 1 |
| 11 | Study of banana and coconut fibers: botanical composition, thermal degradation and textural observations 显示文摘 | Ketty Bilba Marie-Ange Arsene Alex Ouensanga | 2007 | Bioresource Technology2007，98，1： | 1 |
| 12 | 向亚健康SAY NO!显示文摘“自觉不爽,检查无病”,这种介乎疾病与健康之间的状态就是亚健康,也是人体身心整体调整异常的早期反映。现代人往往既需要追求社会角色,同时又肩负家庭的重压,他们在浑然不知的情况下步入了亚健康状态。虽然亚健康的表现从轻度、中度到重度,似乎哪一种症状部不会对身体造成致命的危害,也因此,当发觉自己各种症状都表现为亚健康, | Ketty | 2010 | 现代商业银行2010，，8： | 0 |
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