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| 1 | Endoscopic submucosal dissection for the treatment of neoplastic lesions in the gastrointestinal tract显示文摘AIM: To investigate the indications, resection rate, and safety of endoscopic submucosal dissection (ESD) for neoplastic lesions in the gastrointestinal tract at a European referral center. METHODS: We carried out a retrospective analysis of the ESD procedures performed in our center for mucosal neoplastic and submucosal lesions of the gastrointestinal tract. The duration of the procedure, en bloc and complete (R0) resection rates, and complication rates were evaluated. Variables were reported as mean ± SD or simple proportions. Univariate analysis and comparisons of procedure times and resection rates were performed using Mann-Whitney U tests, or χ2 tests for dichotomous variables.RESULTS: Between 2007 and 2011, ESD was performed in a total of 103 patients (46.7% male, mean age 64.0 ± 12.7 years). The indications for the procedure were epithelial tumor (n = 54), submucosal tumor (n = 42), or other (n = 7). The total en bloc resection rate was 90.3% (93/103) and R0 resection rate 80.6% (83/103). The median speed of the procedure was 15.0 min/cm2 . The complete resection rate was lower for submucosal tumors arising from the muscle layer (68%, 15/22, P < 0.05). Resection speed was quicker for submucosal tumors localized in the submucosal layer than for lesions arising from the muscularis propria layer (8.1 min/cm 2 vs 17.9 min/cm 2 , P < 0.05). The R0 resection rate and speed were better in the last 24 mo (90.1%, 49/54 and 15.3 min/cm 2 ) compared to the first 3 years of treatment (73.5%, 36/49, P < 0.05 and 22.0 min/cm2 , P < 0.05). Complications occurred in 14.6% (n = 15) of patients, including perforation in 5.8% (n = 6), pneumoperitoneum in 3.9% (n = 4), delayed bleeding in 1.9% (n = 2), and other in 2.9% (n = 3). Only one patient with delayed perforation required surgical treatment. During the mean follow-up of 26 ± 15.3 mo, among patients with R0 resection, recurrence occurred in one patient (1.2%).CONCLUSION: ESD is an effective and safe method for resection of neoplastic lesions with low recurrence. Speed and the R0 resection rate increased after 50 procedures. | Andrzej Biaek Anna Wiechowska-Kozowska Jan Pertkiewicz Katarzyna Karpińska Wojciech Marlicz Piotr Milkiewicz Teresa Starzyńska | 2013 | World Journal of Gastroenterology2013,19,12: | 21 |
| 2 | Synchronous and metachronous neoplasms in gastric cancer patients:A 23-year study显示文摘AIM:To determine the prevalence and characteristics of additional primary malignancies in gastric cancer(GC)patients.METHODS:GC patients(862 total;570 men,292women;mean age 59.8±12.8 years)diagnosed at the Department of Gastroenterology at Pomeranian Medical University over a period of 23 years were included in this retrospective analysis of a prospectively maintained database.Mean follow-up time was 31.3±38.6 mo(range 1-241 mo).The following clinicopathological features of patients with synchronous tumors were compared to those with metachronous tumors:age,sex,symptom duration,family history of cancer,tumor site,stage(early vs advanced),histology,and blood group.GC patients with and without a second tumor were compared in terms of the same clinicopathological features.RESULTS:Of 862 GC patients,58(6.7%)developed a total of 62 multiple primary tumors,of which 39(63%)were metachronous and 23(37%)synchronous.Four(6.9%)of the 58 multiple GC patients developed two or more neoplasms.The predominant tumor type of the secondary neoplasms was colorectal(n=17),followed by lung(n=9),breast(n=8),and prostate(n=7).Age was the only clinicopathological feature that differed between GC patients with synchronous vs metachronous malignancies;GC patients with synchronous neoplasms were older than those with metachronous neoplasms(68.0±10.3 years vs 59.9±11.1years,respectively,P=0.008).Comparisons between patients with and without a second primary cancer revealed that the only statistically significant differences were in age and blood group.The mean age of the patients with multiple GC was higher than that of those without a second primary tumor(63.4±11.4years vs 59.5±13.0 years,respectively,P=0.026).GC patients with a second primary tumor were more commonly blood group O than those without(56.2%vs 31.6%,respectively,P=0.002).CONCLUSION:GC patients may develop other primary cancers;appropriate preoperative and postoperative diagnostic modalities are thus required,particularly if patients are older and blood group O. | Magorzata Lawniczak Alicja Gawin Halina Jaroszewicz-Heigelmann Wiesawa Rogoza-Mateja Joanna Raszeja-Wyszomirska Andrzej Biaek Katarzyna Karpińska-Kaczmarczyk Teresa Starzyńska | 2014 | World Journal of Gastroenterology2014,20,23: | 8 |
| 3 | Evidence that thalidomide is effective in recurrent bleeding from watermelon stomach associated with liver cirrhosis显示文摘 | Stephan Moser Alexander Tischer Asia Karpi Michael Schleicher Susanne Stavjanik Michael Gschwantler | 2014 | Endoscopy2014,,: | 2 |
| 4 | Adeno-associated viral genetransfer of transforming growth factor-β1 to hu- man mesenchymal stem cells improves cartilage repair 显示文摘 | Pagnotto MR Wang Z Karpie JC | 2007 | Gene Ther2007,14,: | 1 |
| 5 | Effect of selective laser treatment on initiation of fatigue crack in the main part of an undercarriage drag strut显示文摘This paper presents the results of material characterization and a fatigue test conducted for a laser-re-melted drag strut used in an aircraft landing gear. The drag strut was re-melted with a CO_2 laser beam. Eight re-melted paths were made in the form of spiral lines along the axis of the drag strut. Next, the drag strut was subjected to variable loads on a testing machine simulating loads occurring when an aircraft lands. The fatigue test showed that the laser-treated drag strut was able to withstand 1700 simulated cycles of landing. This result was 70% better than that obtained for a drag strut with no laser treatment. In order to find the reason for the increase in the number of cycles of simulated landings, tests were carried out using transmission and scanning electron microscopes, a computer microtomograph, an X-ray diffractometer, and a nanoindenter,respectively. Results of the conducted research indicated that the reasons for the increased fatigue life of the laser-treated undercarriage drag strut were both an ultra-fine cellular martensitic microstructure and compressing residual stresses generated during the laser re-melting of the surface layer of the material. | Anna BIE? Marek SZKODO Jerzy DOBERSKI Bart?omiej KARPI?SKI | 2019 | Chinese Journal of Aeronautics2019,32,3: | 1 |
| 6 | Item-based top-n recommendation algorithms显示文摘 | DESHPANDE M KARPIS G | | 0,,01: | 1 |
| 7 | Effect of glass-crystalline and amorphous binder application to abrasive tools made of microcrystalline alumina grains type SG显示文摘 | Herman D Pliehta J and Karpi ski T | 1997 | Wear1997,209,1: | 1 |
| 8 | Adeno-associated vi- ral gene transfer of transforming growth factor-131 to human mes- enchymal stem ceils improves cartilage repair 显示文摘 | Pagnotto MR Wang Z Karpie JC | 2007 | Gene Ther2007,,14: | 1 |
| 9 | Heterotopic Pancreas in the Stomach (Type II According to Heinrich) - Literature Review and Case Report显示文摘 | Marta Karpińska Miros?aw Nienartowicz Alicja Markowska-Woyciechowska Katarzyna Budrewicz-Czapska | 2011 | Polish Journal of Surgery2011,,3: | 1 |
| 10 | Adeno-associated viral gene transfer of transforming growth factor-betal to human mesenchymal stem cells improves cartilage repair显示文摘 | Pagnotto MR Wang Z Karpie JC | 2007 | Gene ther2007,14,10: | 1 |
| 11 | Treatment of large colorectal neoplasms by endoscopic submucosal dissection: a European single-center study显示文摘 | Andrzej Bia?ek Jan Pertkiewicz Katarzyna Karpińska Wojciech Marlicz Dariusz Bielicki Teresa Starzyńska | 2014 | European Journal of Gastroenterology & Hepatology2014,,6: | 1 |
| 12 | Hydrodechlorination of CCl4 on Pt–Au/Al2O3 Catalysts显示文摘 | Marta Legawiec-Jarzyna Wojciech Juszczyk Magdalena Bonarowska Zbigniew Kaszkur Leszek K?piński Zbigniew Kowalczyk Zbigniew Karpiński | 2009 | Topics in Catalysis2009,,8: | 1 |
| 13 | Adeno-associated viral gene transfer of transforming growth factor-beta1 to human mesenchymal stem cells improves cartilage repair显示文摘 | Pagnotto MR Wang Z Karpie JC | | 0,,10: | 1 |
| 14 | Adeno-associated viralgene transfer of transforming growth factor-betal to humanmesenchymal stem cells improves cartilage repair显示文摘 | Pagnotto M R Wang Z Karpie J C | 2007 | Gene Ther2007,14,10: | 1 |
| 15 | Role of ultrasonography in diagnosis and differentiation of pleomorphic adenomas:work in progress显示文摘 | Biaek EJ Jakubowski W Karpińska G | 2003 | Arch Otolaryngol Head Neck Surg2003,129,9: | 1 |
| 16 | Serum levels of interleukin-6,interleukin-10 and C-reactive protein in relation to left ventricular function in patients with myocardial infarction treated with primary angioplasty显示文摘 | Karpiński L Pnaksej R Kosmala W | 2008 | Kardiol Pol2008,66,12: | 1 |
| 17 | Charateristic of bacterincines and their application显示文摘 | KARPISKI T M SZKARADKIEWICZ A K | 2013 | Polish Journal of Microbidogy2013,62,3: | 1 |
| 18 | Bacteriocins显示文摘 | Karpiński T M Szkaradkiewicz A K | 2015 | Reference Module in Food Science Encyclopedia of Food and Health2015,18,9: | 1 |
| 19 | Carbonylation of aromatic dinitro compounds with carbon monoxide to respective diearbamates in the presence of the PdCl2/Fe/I2/Py catalytic system显示文摘 | Karpi n ska M Skupi ri ska J Barana P | 2009 | J Mol Catal A:Chem2009,303,12: | 1 |
| 20 | Lidocaine exhibits dose- and time-dependent cytotoxic effects on bovine articular chondrocytes in vitro显示文摘 | Karpie JC Chu CR | | 0,,10: | 1 |