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| 1 | Immediate detection of endoscopic retrograde cholangiopancreatographyrelated periampullary perforation: Fluoroscopy or endoscopy?显示文摘AIM:To investigate the causes and intraoperative detection of endoscopic retrograde cholangiopancreatography(ERCP)-related perforations to support immediate or early diagnosis.METHODS:Consecutive patients who underwent ERCP procedures at our hospital between January2008 and June 2013 were retrospectively enrolled in the study(n=2674).All procedures had been carried out using digital fluoroscopic assistance with the patient under conscious sedation.For patients showing alterations in the gastrointestinal anatomy,a short-type double balloon enteroscope had been applied.Cases of perforation had been identified by the presence of air in or leakage of contrast medium into the retroperitonealspace,or upon endoscopic detection of an abdominal cavity related to the perforated lumen.For patients with ERCP-related perforations,the data on medical history,endoscopic findings,radiologic findings,diagnostic methods,management,and clinical outcomes were used for descriptive analysis.RESULTS:Of the 2674 ERCP procedures performed during the 71-mo study period,only six(0.22%)resulted in perforations(male/female,2/4;median age:84 years;age range:57-97 years).The cases included an endoscope-related duodenal perforation,two periampullary perforations related to endoscopic sphincterotomy,two periampullary perforations related to endoscopic papillary balloon dilation,and a periampullary or bile duct perforation secondary to endoscopic instrument trauma.No cases of guidewire-related perforation occurred.The video endoscope system employed in all procedures was only able to immediately detect the endoscope-related perforation;the other five perforation cases were all detected by subsequent digital fluoroscope applied intraoperatively(at a median post-ERCP intervention time of 15 min).Three out of the six total perforation cases,including the single case of endoscope-related duodenal injury,were surgically treated;the remaining three cases were treated with conservative management,including trans-arterial embolization to control the bleeding in one of the cases.All patients recovered without further incident.CONCLUSION:ERCP-related perforations may be difficult to diagnose by video endoscope and digital fluoroscope detection of retroperitoneal free air or contrast medium leakage can facilitate diagnosis. | Yasuaki Motomura Kazuya Akahoshi Junya Gibo Kenji Kanayama Shinichiro Fukuda Shouhei Hamada Yoshihiro Otsuka Masaru Kubokawa Kiyoshi Kajiyama Kazuhiko Nakamura | 2014 | World Journal of Gastroenterology2014，20，42： | 5 |
| 2 | Essential role of gastric gland mucin in preventing gastric cancer in mice显示文摘 | Karasawa Fumitoshi Shiota Akira Goso Yukinobu Kobayashi Motohiro Sato Yoshiko Masumoto Junya Fujiwara Maiko Yokosawa Shuichi Muraki Takashi Miyagawa Shinichi Ueda Masatsugu Fukuda Michiko N Fukuda Minoru Ishihara Kazuhiko Nakayama Jun | 2012 | EN2012，，3： | 1 |
| 3 | Overexpression of eukaryotic elongation factor eEF2 in gastrointestinalcancers and its involvement in G2/M progression in the cell cycle显示文摘 | Junya Nakamura Sayaka Aoyagi Isamu Nanchi Shin-Ichi Nakatsuka Erika Hirata Shohei Shibata Mari Fukuda Yumiko Yamamoto Ikuyo Fukuda Naoya Tatsumi Tazu Ueda Fumihiro Fujiki Masaya Nomura Sumiyuki Nishida Toshiaki Shirakata Naoki Hosen Akihoro Tsuboi Yoshihi | 2009 | International Journal of Oncology2009，，： | 1 |
| 4 | Wilms’ tumor gene WT1-shRNA as a potent apoptosis-inducing agent forsolid tumors显示文摘 | Naoya Tatsumi Yusuke Oji Naoko Tsuji Asako Tsuda Mari Higashio Sayaka Aoyagi Ikuyo Fukuda Ken Ito Junya Nakamura Satoshi Takashima Yayoi Kitamura Saori Miyai Tanyarat Jomgeow Zheyu Li Toshiaki Shirakata Sumiyuki Nishida Akihiro Tsuboi Yoshihiro Oka Haruo | 2008 | International Journal of Oncology2008，，： | 1 |
| 5 | Phase transitions between tropical,subtropical,and extratropical cyclones:A review from IWTC-10显示文摘This review,which was adapted from a Tenth International Workshop on Tropical Cyclones(IWTC-10)report,discusses research findings and operational practices relevant to cyclone types and phase transitions(extratropical,subtropical,and tropical).The cyclone phase space(CPS)method is widely used in both historical investigations and real-time evaluation of cyclone type and transition;however,CPS parameter values depend on input data resolution,and universal thresholds do not currently exist to delineate when a cyclone transitions from one type to another.Assessments of phase transitions in a changing climate highlight potential latitude shifts in extratropical transition and increased potential for tropical transition,but realistic projections of future trends likely require high-resolution simulations that can capture the cyclone warm core.Operational meteorological centers apply varied approaches to cyclone classification via CPS parameters and other criteria,some of which depend on the tropical basin,yet these approaches cannot fully address challenges in operational classification and subsequently in communicating risks associated with these phase transitions.We recommend a multivariate historical assessment of tropical and subtropical cyclones across all basins in which they occur,including the South Atlantic Ocean and the Mediterranean Sea,to identify the potential for a more universal cyclone classification approach that meets operational needs. | Kimberly Wood Wataru Yanase Jack Beven Suzana J.Camargo Joseph B.Courtney Chris Fogarty Junya Fukuda Naoko Kitabatake Matthew Kucas Ron McTaggart-Cowan Michelle Simoes Reboita Jacopo Riboldi | 2023 | Tropical Cyclone Research and Review2023，12，4： | 0 |
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