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6篇 您的检索式:作者名="Junxia Ran"
    题名 作者 年代 出处 被引量
1Direct measurement of electron density in microdischarge at atmospheric pressure by Stark broadening显示文摘Dong Lifang Ran Junxia Mao Zhiguo 2005Applied Physics Letterrs2005,86,16:1
2Direct measurement of electron density in microdischarge at atmospheric pressure by stark broadening显示文摘 Ran Junxia Mao Zhiguo 2005Appl Phys Lett2005,86,16:1
3Direct Meas- urement of Electron Density in Micro- Discharge at Atmospheric Pressure by Stark Broadening显示文摘Dong Lifang Ran Junxia Mao Zhiguo 2005Ap- plied Physics Letters2005,86,16:1
4Direct measurement of electron density in microdischarge at atmospheric pressure by Stark broadening显示文摘DONG Lifang RAN Junxia MAO Zhiguo 2005Appl Phys Lett2005,86,16:1
5Periostin promotes EMT via inhibition of RIN1-mediated endocytosis of EGFR in gliomas显示文摘Purpose:Approximately 1/3 of brain tumors are gliomas.Previous glioma-related studies have reported increased expression of periostin(POSTN)in these cancerous tissues,but the role and mechanism of POSTN in glioma development remain unclear.Methods:Nanoscale liquid chromatography coupled with tandem mass spectrometry(nano LC-MS/MS)and RNA sequencing were used to identify diferential protein and mRNA expression in clinical glioma samples.Quantitative real-time PCR(qRT-PCR)was used to measure the expression of POSTN in tissues and cells.The efects of POSTN on glioma cell migration and invasion were examined using wound healing,Transwell,and three-dimensional spheroid assays in vitro and a nude mouse xenograft model in vivo.The efects of POSTN on the stability,endocytosis,and degradation of EGFR were examined by immunoblotting and immunofuorescence staining.Truncation mutation analysis was performed to investigate direct interactions between POSTN and EGFR.Immunohistochemical staining was carried out to confrm the clinical signifcance of POSTN.Results:Overexpression of POSTN induced epithelial-to-mesenchymal transition(EMT)in glioma cells in vivo and in vitro.Mechanistically,POSTN downregulation inhibited EGFR signaling by promoting EGFR endocytosis and degradation.In addition,POSTN was found to bind to EGFR and RIN1,inhibiting EGFR endocytosis and degradation and thus activating the PI3K-Akt signaling pathway.Conclusion:These fndings indicate the mechanism by which the POSTN/EGFR/RIN1 axis inhibits EGFR endocytosis and degradation,resulting in glioma cell EMT through the PI3K-AKT signaling pathway.Targeting POSTN/EGFR/RIN1 interactions may guarantee benefcial outcomes of glioma treatment.Fengqi Zhou Tianfu Yu Fan Xiao Binbin Wang Wei Tian Ran Xu Xiaochun Zhao Ailiang Zeng Ning Liu Yingyi Wang Yongping You Junxia Zhang 2022Holistic Integrative Oncology2022,1,1:0
6A double‐mode planar argon plume produced by varying the distance from an atmospheric pressure plasma jet显示文摘Atmospheric pressure planar plumes are desirable for the applications of low temperature plasmas,such as rapid modification of large‐scale surfaces.Up to now,only single‐mode planar plumes with either a streamer mode or a filamentary mode have been reported in the literature.Distinctive from the single‐mode planar plumes,a double‐mode argon planar plume has been generated in this article,which operates in the streamer mode with a larger distance away from a plasma jet and transits to the filamentary mode with decreasing the distance.Discharge characteristics and plasma parameters are compared for the two modes.Results indicate that the streamer mode and the filamentary mode correspond to pulsed and humped discharges respectively.Fast photography reveals that the streamer‐mode plume is composed of stochastically branching streamers,while the filamentary‐mode plume results from a series of moving filaments similar to those in barrier discharge.In contrast to the streamer mode,the filamentary mode has lower excited electron temperature and vibrational temperature,whereas higher electron density and gas temperature.In addition,better hydrophilicity of polyethylene terephthalate surface is achieved in the filamentary mode.Kaiyue Wu Jingnan Liu Jiacun Wu Mo Chen Junxia Ran Xuexia Pang Pengying Jia Xuechen Li Chenhua Ren 2023High Voltage2023,8,6:0
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