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| 1 | Participation of epididymal cysteine-rich secretory proteins in sperm-egg fusion and their potential use for male fertility regulation显示文摘老鼠蛋白质 DE 是一个雄激素依赖者充满半胱氨酸的能分泌的蛋白质(松脆) 由近似附睾区域综合了。DE,也作为 CRISP-1 知道,在反应 acrosome 的精子的赤道的片断上是局部性的并且通过绑定参予配偶子熔化到鸡蛋互补地点。有 DE 的老鼠的免疫禁止富饶和精子熔化能力,建议 DE 代表一个好附睾避孕药目标。Recombinant 整理碎片和合成的肽表明 DE 经由 anevolutionarily 保存的主题的一个 12-amino 酸区域绑在卵,签名 2 (S2 ) 。松脆的其它的能力与他们的 S2 氨基酸序列被相关绑在老鼠卵。尽管阴囊的蛋白质 Tpx-1 (CRISP-2 ) 能够到啮齿类动物卵的绑定,人的附睾的 AEG 相关的蛋白质(ARP ) 和 helothermine (从蜥蜴口水) 不。S2 区域在 Tpx-1 介绍了仅仅二替换并且四在 ARPand helothermine,与 DE S2 相比,建议这氨基酸定序为鸡蛋是相关的相互作用。有 Tpx-1 和 anti-Tpx-1 的研究在卵通过绑定在配偶子熔化揭示了这蛋白质的参予到互补地点。在比赛研究, DE dose-dependently 减少了 Tpx-1 的绑定,显示那两个松脆的份额卵互补地点。当认出仅仅相应蛋白质时,那 anti-DE 和 anti-Tpx-1 禁止精子鸡蛋熔化,建议在这些之间的功能的合作相应对松脆保证授精成功。这些结果增加我们配偶子熔化的分子的机制的理解并且贡献调整方法的新、更安全的富饶的发展。 | Debora J. Cohen Vanina G. Da Ros Dolores Busso Diego A. Ellerman Julieta A. Maldera Nadia Goldweic Patricia S. Cuasnicti | 2007 | Asian Journal of Andrology2007，9，4： | 16 |
| 2 | Role of quorum sensing in bacterial infections显示文摘Quorum sensing(QS) is cell communication that is widely used by bacterial pathogens to coordinate the expression of several collective traits, including the production of multiple virulence factors, biofilm formation, and swarming motility once a population threshold is reached. Several lines of evidence indicate that QS enhances virulence of bacterial pathogens in animal models as well as in human infections; however, its relative importance for bacterial pathogenesis is still incomplete. In this review, we discuss the present evidence from in vitro and in vivo experiments in animal models, as well as from clinical studies, that link QS systems with human infections. We focus on two major QS bacterial models, the opportunistic Gram negative bacteria Pseudomonas aeruginosa and the Gram positive Staphylococcus aureus, which are also two of the main agents responsible of nosocomial and wound infections. In addition, QS communication systems in other bacterial, eukaryotic pathogens, and even immune and cancer cells are also reviewed, and finally, the new approaches proposed to combat bacterial infections by the attenuation of their QS communication systems and virulence are also discussed. | Israel Castillo-Juárez Toshinari Maeda Edna Ayerim Mandujano-Tinoco María Tomás Berenice Pérez-Eretza Silvia Julieta García-Contreras Thomas K Wood Rodolfo García-Contreras | 2015 | World Journal of Clinical Cases2015，3，7： | 15 |
| 3 | Changes in leaflet shape and seeds per pod modify crop growth parameters, canopy light environment, and yield components in soybean显示文摘Seed number(SN)is the component most strongly associated with yield in soybean.SN depends on pod number(PN)and seeds per pod(SPP).Whereas SPP is a relatively stable component,PN is strongly influenced by environmental and management factors.However,the environmental cues involved in PN regulation are not completely understood.The influence of increasing SPP on other yield components is controversial.Field trials were conducted in two growing seasons using two pairs of lanceolate(L)and ovate(O)nearisogenic lines,sown at low(LD)and high(HD)plant densities to evaluate the effect of leaflet shape on crop growth parameters,canopy red/far-red(R/FR)ratio,their relationships with pod initiation,PN,and yield;and the effect of increasing SPP on PN,SN,and yield.L canopies showed a higher number of pods initiated(PI)than O canopies owing to the increase of PI on branches.No association between PI and crop growth rate during the pod set period was found.PI was negatively associated with leaf area index(LAI)and light interception.In contrast,a positive association between PI and canopy R/FR ratio was found.This latter association was sustained irrespective of whether the LAI was below or above its critical value,providing experimental evidence that R/FR ratio is positively associated with pod initiation in soybean canopies.An increase in SPP produced a direct and steady increase in SN regardless of PN and plant density.A yield increase was observed for the L-LD treatment,which combined the increased SPP of L lines with the highest PN of L-LD canopies.These results have implications for crop management and breeding strategies aimed at increasing the yield potential of soybean. | Julieta S.Bianchi Alvaro Quijano Carlos O.Gosparini | 2020 | The Crop Journal2020，8，2： | 4 |
| 4 | 电除颤前进行一定时间的心肺复苏对延迟的心室纤颤作用的研究显示文摘目的 :探讨对由延迟的心室纤颤引起的心脏骤停的治疗方法。方法 :将 32只延迟心室纤颤 (10分钟心室纤颤 )动物模型的大鼠随机分为 4组 (0 -min组 ,2 -min组 ,4-min组及 6 -min组 ) ,分别在心肺复苏前、心肺复苏后 2分钟、4分钟、6分钟行试验电除颤 ,对未能转复者继续心肺复苏及补救电除颤。结果 :0 -min组 ,2 -min组无大鼠能通过试验电除颤成功恢复自主心率 ,而 6 -min组有 7只大鼠 ;与另外两组相比 ,4-min组及 6 -min组具有更长的生存时间。此外 ,6 -min组恢复自主心率所需的试验电除颤次数、补救电除颤次数及总除颤能量均显著地较其他三组为低。结论 :我们认为对延迟的心室纤颤在电除颤前应进行至少 4~ 6分钟的心肺复苏。 | 易忠 Rual J.Gazmuri Julieta D.Kolarova Iyad M.Ayoub | 2002 | 广西医学2002，24，7： | 4 |
| 5 | Induction of apoptosis on human hepatocarcinoma cell lines by an alkyl resorcinol isolated from Lithraea molleoides显示文摘AIM: To study the mechanism of cytotoxicity of a new active 5-alkyl resorcinol [1, 3-dihydroxy-5- (tridec-4’, 7’ -dienyl) benzene] isolated from Lithraea molleoides leaves on liver tumor cells. METHODS: Human hepatocarcinoma cell lines (HepG2 and Hep3B) in culture were treated with inhibitory concentrations, 50% of the compound, for 24 h. The induction of apoptosis was detected in treated cells by analysis of DNA fragmentation, DNA content, and acridine orange and propidium iodide staining. RESULTS: After 24 h of 5-alkyl resorcinol treatment, both cell lines showed: (1) the typical morphological alterations of apoptosis; (2) DNA fragmentation, detected by laddering and appearance of a subG0 population by flow cytometry; and (3) condensed and fragmented nuclei by acridine orange-propidium iodide staining. CONCLUSION: Based on the results, this compound exerts its cytotoxic effect in both hepatocellular cell lines through apoptotic cell death. For Hep3B, cells with mutated p53 and Fas, apoptosis would proceed by p53- or Fas-independent pathways. | Luciana Barbini Paula Lopez Julieta Ruffa Virginia Martino Graciela Ferraro Rodolfo Campos Lucia Cavallaro | 2006 | World Journal of Gastroenterology2006，12，37： | 3 |
| 6 | Phylogenomics,biogeography,and evolution of the blue-or white-fruited dogwoods(Cornus)-Insights into morphological and ecological niche divergence following intercontinental geographic isolation显示文摘The eastern Asian(EA)-eastem North American(ENA)floristic disjunction represents a major pattern of phytogeography of the Northern Hemisphere.Despite 20 years of studies dedicated to identification of taxa that display this disjunct pattern,its origin and evolution remain an open question,especially regarding postisolation evolution.The blue-or white-fruited dogwoods(BW)are the most species-rich among the four major clades of Cornus L.,consisting of-35 species divided into three subgenera(subg.Yinquania,subg.Mesomora,and subg.Kraniopsis).The BW group provides an excellent example of the EA-ENA floristic disjunction for biogeographic study due to its diversity distribution centered in eastern Asia and eastern North America,yet its species relationships and delineation have remained poorly understood.In this study,we combined genome-wide markers from RAD-seq,morphology,fossils,and climate data to understand species relationships,biogeographic history,and ecological niche and morphological evolution.Our phylogenomic analyses with RAxML and MrBayes recovered a strongly supported and well-resolved phylogeny of the BW group with three intercontinental disjunct clades in EA and ENA or Eurasia and North America,of which two are newly identified within subg.Kraniopsis.These analyses also recovered a potential new species but failed to resolve relationships within the C.hemsleyi-C.schindleri complex.In an effort to develop an approach to reduce computation time,analysis of different nodal age settings in treePL suggests setting a node's minimum age constraint to the lower bound of a fossil's age range to obtain similar ages to that of BEAST.Divergence time analyses with BEAST and treePL dated the BW stem back to the very Late Cretaceous and the divergence of the three subgenera in the Paleogene.By integrating fossil ages and morphology,a total evidence-based dating approach was used in conjunction with time-slice probabilities of dispersal under a DEC model to resolve ancestral ranges of each disjunct in the Miocene:Eurasia and ENA(disjunct 1),EA and western North America(disjunct 2),and EA(disjunct 3).The dated biogeographic history supports dispersal via the North Atlantic Land Bridge in the late Paleogene in disjunct 1 and dispersal via the Bering Land Bridge in the Miocene for disjuncts 2 and 3.Character mapping with a stochastic model in phytools and comparison of ecological niche,morphospace,and rate of evolution indicated differential divergence patterns in morphology,ecological niche,and molecules between disjunct sisters.Although morphological stasis was observed in most of the characters,evolutionary changes in growth habit and some features of leaf,flower,and fruit morphology occurred in one or both sister clades.A significant differentiation of ecological habitats in temperature,precipitation,and elevation between disjunct sisters was observed,suggesting a role of niche divergence in morphological evolution post-isolation.The patterns of evolutionary rate between morphology and molecules varied among disjunct clades and were not always congruent between morphology and molecules,suggesting cases of non-neutral morphological evolution driven by ecological selection.Our phylogenetic evidence and comparisons of evolutionary rate among disjunct lineages lend new insights into the formation of the diversity anomaly between EA and ENA,with particular support of an early diversification in EA.These findings,in conjunction with previous studies,again suggest that the EA-ENA disjunct floras are an assembly of lineages descended from the Mesophytic Forests that evolved from the early Paleogene“boreotropical flora”through varied evolutionary pathways across lineages. | Kira Lindelof Julieta ALindo Wenbin Zhou Xiang Ji Qiu-Yun(Jenny)Xiang | 2020 | Journal of Systematics and Evolution2020，58，5： | 3 |
| 7 | Aspects of forest restoration and hydrology:the hydrological function of litter显示文摘Although forests play important roles in the hydrological cycle,there is little information that relates the water retention capacity of litter in areas under passive restoration,especially in Cerrado savannas.This study relates litter levels to water holding capacity and effective water retention among forest fragments under different passive restoration stages:46,11,and 8 years to better understand litter hydrological functions in the Cerrado.Water retention capacity and effective water retention capacity of litters(unstructured materials,branches and leaves)in the field were monitored on a monthly basis.Total litter accumulation at 46 years was significantly higher than that of the other succession stages.Unstructured litter mass was significantly higher than that of leaves and branches.The 46-year stage had the highest water holding capacity in the leaf fraction,followed by unstructured material and branches.Although the water holding capacity was lower in the oldest resto-ration,this site showed the highest efficiency under field conditions.The process was quickly reestablished,as the 11-year restoration showed results closer to that for the 46-year stage in comparison to the area at 8 years.Thus,passive restoration plays a key role in soil water mainte-nance due to the influence of litter in Cerrado savannas.Deforestation and the imminent need of restoring degraded sites,highlight the need for further studies focused on bet-ter understanding of the process of forest restoration and its temporal effect on soil water recovery dynamics. | Luara Castilho Pereira Leonardo Balbinot Marcelle Teodoro Lima Julieta Bramorski Kelly Cristina Tonello | 2022 | Journal of Forestry Research2022，33，2： | 3 |
| 8 | Effects of heavy metal concentrations (Cd, Zn and Pb) in agricultural soils near different emission sources on quality, accumulation and food safety in soybean [ Glycine max (L.) Merrill]显示文摘 | María Julieta Salazar Judith Hebelen Rodriguez Gastón Leonardo Nieto María Luisa Pignata | 2012 | Journal of Hazardous Materials2012，，： | 2 |
| 9 | Infections and inequalities: anemia in AIDS, the disadvantages of poverty显示文摘Objective:To study anemia in AIDS patients and its relation with socioeconomic, employment status and educational levels.Methods:A total number of 442 patients who visited the Infectious Diseases University Hospital in Buenos Aires, Argentina were included in the study. Patients were dividied into two groups,i.e.one with anemia and the other without anemia. Anemia epidemiology and its relationship with educational level, housing, job situation, monthly income, total daily caloric intake and weekly intake of meat were evaluated.Results:Anemia was found in 228 patients(54%). Comparing patients with or without anemia, a statistically significant difference was found(P<0.0001) in those whose highest educational level reached was primary school, who lived in a precarious home, who had no stable job or were unable to work, whose income was less than 30 dollars per month, whose meat consumption was less than twice a week or received less than 8000 calories per day.Conclusions:The high prevalence of anemia found in poor patients with AIDS suggests that poverty increases the risk to suffer from this hematological complication.The relationship between economic development policies and AIDS is complex. Our results seem to point to the fact that AIDS epidemic may affect economic development and in turn be affected by it. If we consider that AIDS affects the economically active adult population, despite recent medical progress it usually brings about fatal consequences, especially within the poorest sectors of society where the disease reduces the average life expectancy, increases health care demand and tends to exacerbate poverty and iniquity. | Lucia Gonzalez Celeste Seley Julieta Martorano Isabella Garcia-Moreno Alcides Troncoso | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，6： | 2 |
| 10 | The impact of the COVID-19 pandemic on the mental health of young people:A comparison between China and the United Kingdom显示文摘Purpose:As COVID-19 spreads globally and affects people's health,there are concerns that the pandemic and control policies may have psychological effects on young people(age from 17 to 35 years).This psychological impact might vary in different countries,and thus we compared the prevalence of self-reported psychological distress,loneliness and posttraumatic stress symptoms(PTSS)among young people in the United Kingdom(UK)and China at the beginning of the COVID-19 pandemic.Methods:Data of this study came from two sources.One source was the first wave of COVID-19 study in Understanding Society,a special wave of the UK household longitudinal study,which provided the high-quality,national-wide representative panel data.The sample comprised 1054 young people.The other source was an online survey on the mental health of 1003 young people from Shanghai,a highly developed area in China.The questionnaire included questions on the prevalence of common mental disorders(cut-off score≥4),loneliness and potential PTSS(cut-off≥33).Univariable analyses were conducted to test the differences in the self-reported prevalence of psychological distress and loneliness between the two groups.Multivariable logistic regression analyses were run to explore the predictors of psychological distress and loneliness among all the young people from England and Shanghai.Results:Among the samples with self-reported psychological distress,the UK sample accounted for 34.4%(n=1054)and the Chinese sample accounted for 14.1%(n=1003).The difference between the two groups was statistically significant(p<0.001).Additionally,57.1%of people in the UK and 46.7%in China reported that they sometimes or often felt lonely,of which the difference is statistically significant(p<0.001).Regression analysis of the entire samples showed that nationality,gender,psychotherapy and loneliness were significant predictors of 12-item General Health Questionnaire scores,while the variables of age and living alone were not.Significant predictors of self-reported loneliness were the nationality,gender,age,living alone and psychotherapy.In China,123(12.3%)young people,49 men(11.3%)and 74 women(13.0%),met the criteria of PTSS symptoms(cut-off scores≥33).These scores were only collected in China.Conclusion:This evidence suggests that mental health and loneliness reported by young people were lower in China than that in the UK during the studied period.More research is needed to understand these differences.If the differential negative psychological impacts are confirmed,country-specific measures of prevention and intervention should be adopted to improve the mental health of young people under the ongoing impact of the pandemic. | Ming-Bo Liu Geraldine Dufour Zhuo-Er Sun Julieta Galante Chen-Qi Xing Jing-Ye Zhan Li-Li Wu | 2021 | Chinese Journal of Traumatology2021，24，4： | 2 |
| 11 | A three-dimensional acoustics model using the method of fundamental solutions显示文摘 | Julieta Antonio Antonio Tadeu Luis Godinho | 2008 | Engineering Analysis with Boundary Elements2008，32，： | 1 |
| 12 | Nutritional value of edible insect from the state of Oaxaca, Mexico显示文摘 | JULIETA R E JOSE M P M ESTEBAN E P | 1997 | Journal of Food Composition and Analysis1997，10，2： | 1 |
| 13 | Sound insulation provided by single and double panel walls a comparison of analytical solutions versus experimental results 显示文摘 | Antonio Tadeu Julieta Antonio Diogo Mateus | 2004 | Applied Acoustics2004，65，： | 1 |
| 14 | Photosynthetic and gas exchange characteristics of dominant woody plants on a moisture gradient in an African savanna显示文摘 | GUY F M JULIETA N A KHANYISA B M etal | 2004 | Global Change Biology2004，10，3： | 1 |
| 15 | RAPD and ISSR molecular markers in Olea europaea L.: Genetic variability and molecular cultivar identification显示文摘 | Paula Martins-Lopes José Lima-Brito Sónia Gomes Julieta Meirinhos Luís Santos Henrique Guedes-Pinto | 2007 | Genetic Resources and Crop Evolution2007，，1： | 1 |
| 16 | The role of mossy cell death and activation of protein synthesis in the sprouting of dentate mossy fiberss Evidence from calretinin and Neo-timm staining in pilocarpine-epileptic mice显示文摘 | Julieta G Silva S Luiz E | 2000 | Epilepsia2000，41，6： | 1 |
| 17 | Nitrogen cycling in the soil-plant system along a precipitation gradient in the Kalahari sands显示文摘 | Julieta N A Luanne O Stephen A M | 2004 | Global Change Biology2004，10，： | 1 |
| 18 | Differences in Browning Index and CIELAB Coordinates of the Two Grape Drying Processes, Traditional Sun-Drying and Chamber-Drying and during the Ageing of Pedro Ximenez Sweet Wine显示文摘 | Maria P. Serratosa Ana Marquez Azahara Lopez-Toledano Manuel Medina Julieta Merida | 2011 | Journal of Life Sciences2011，5，11： | 1 |
| 19 | 钠氢离子交换抑制剂Cariporide与肾上腺素联合用于延迟心室纤颤的心肺复苏显示文摘目的 探讨联合应用钠氢离子交换抑制剂(NHE I)Cariporide与肾上腺素在心肺复苏中的效果。方法 16只历经 12min室颤的大鼠配对分为 2组 (Cariporide组及对照组 ) ,分别在心肺复苏 (CPR)前注入Cariporide或等容量的生理盐水。CPR第 2min结束前始注入肾上腺素 ,使CPP维持在 2 5mmHg以上。对照组与匹配的Cariporide组有对应的除颤时间。对心肺复苏 8min后未能自动复率大鼠进行电除颤。结果 与对照组相比 ,以同样的高度进行胸前心脏按压 ,cariporide组须较小剂量的肾上腺素便可获得较高、持续时间较长的冠脉灌注压 (P <0 0 5 ) ,较高的复苏率 (P <0 0 5 )、较少的复苏后异位室性心律失常 (P <0 0 0 1)、较好的血流动力学效果及较长的生存时间 (P <0 0 5 )。结论 联合应用Cariporide及肾上腺素可提高心室纤颤的复苏效果。 | 易忠 Rual J.Gazmuri Iyad M.Ayoub Julieta D.Kolarova | 2002 | 岭南心血管病杂志2002，8，3： | 1 |
| 20 | A new experimental model of glaucoma in rats through intracameral injections of hyaluronic acid显示文摘 | María Cecilia Moreno Hernán J. Aldana Marcos J. Oscar Croxatto Pablo H. Sande Julieta Campanelli Carolina O. Jaliffa Jorge Benozzi Ruth E. Rosenstein | 2005 | Experimental Eye Research2005，，1： | 1 |
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