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| 1 | Genome Characteristics and Evolution of Pseudorabies Virus Strains in Eastern China from 2017 to 2019显示文摘Since late 2011,outbreaks of pseudorabies virus(PRV)have occurred in southern China causing major economic losses to the pig industry.We previously reported that variant PRV forms and recombination in China could be the source of continued epidemics.Here,we analyzed samples from intensive pig farms in eastern China between 2017 and 2019,and sequenced the main glycoproteins(gB,gC,gD,and gE)to study the evolution characteristics of PRV.Based on the gC gene,we found that PRV variants belong to clade 2 and detected a founder effect during by the PRV epidemic.In addition,we detected inter-and intra-clade recombination;in particular,inter-clade recombination in the gB genes of strains FJ-ZXF and FJ-W2,which were recombinant with clade 1 strains.We also found specific amino-acid changes and positively selected sites,possibly associated with functional changes.This analysis of the emergence of PRV in China illustrates the need for continuous monitoring and the development of vaccines against specific variants of PRV. | Xiaofeng Zhai Wen Zhao Kemang Li Cheng Zhang Congcong Wang Shuo Su Jiyong Zhou Jing Lei Gang Xing Haifeng Sun Zhiyu Shi Jinyan Gu | 2019 | Virologica Sinica2019，34，6： | 12 |
| 2 | Comparative Genome Analysis of Scutellaria baicalensis and Scutellaria barbata Reveals the Evolution of Active Flavonoid Biosynthesis显示文摘Scutellaria baicalensis(S.baicalensis)and Scutellaria barbata(S.barbata)are common medicinal plants of the Lamiaceae family.Both produce specific flavonoid compounds,including baicalein,scutellarein,norwogonin,and wogonin,as well as their glycosides,which exhibit antioxidant and antitumor activities.Here,we report chromosome-level genome assemblies of S.baicalensis and S.barbata with quantitative chromosomal variation(2 n=18 and 2 n=26,respectively).The divergence of S.baicalensis and S.barbata occurred far earlier than previously reported,and a whole-genome duplication(WGD)event was identified.The insertion of long terminal repeat elements after speciation might be responsible for the observed chromosomal expansion and rearrangement.Comparative genome analysis of the congeneric species revealed the species-specific evolution of chrysin and apigenin biosynthetic genes,such as the S.baicalensis-specific tandem duplication of genes encoding phenylalanine ammonia lyase and chalcone synthase,and the S.barbata-specific duplication of genes encoding 4-Co A ligase.In addition,the paralogous duplication,colinearity,and expression diversity of CYP82 D subfamily members revealed the functional divergence of genes encoding flavone hydroxylase between S.baicalensis and S.barbata.Analyzing these Scutellaria genomes reveals the common and species-specific evolution of flavone biosynthetic genes.Thus,these findings would facilitate the development of molecular breeding and studies of biosynthesis and regulation of bioactive compounds. | Zhichao Xu Ranran Gao Xiangdong Pu Rong Xu Jiyong Wang Sihao Zheng Yan Zeng Jun Chen Chunnian He Jingyuan Song | 2020 | Genomics, Proteomics & Bioinformatics2020，18，3： | 10 |
| 3 | Applicability of five models to simulate water infiltration into soil with added biochar显示文摘As a soil amendment, biochar can reduce soil bulk density, increase soil porosity, and alter soil aggregates and thus affect the infiltration. Researchers have proposed and revised several theoretical models to describe the process of soil infiltration. Although these models have been successfully used to evaluate the soil infiltration in different scenarios in agricultural fields, little effort has been devoted to assess their performances in arid and semi-arid soils after the addition of biochar. A laboratory experiment was performed to study the infiltration characteristics of two typical Loess Plateau soils at three particle sizes(2–1, 1–0.25, and <0.25 mm) and five biochar application amounts(0, 10, 50, 100, and 150 g/kg). The performance of five models(i.e., the Philip model, Kostiakov model, Mezencev model, USDA-NRCS model, and Horton model) in simulating the infiltration process was then evaluated based on the adjusted coefficient of determination and a reduced Chi-Square test. Results indicated that the Horton model best simulated the water-infiltration process in an aeolian sandy soil with added biochar. However, the Mezencev model best simulated the infiltration process in a loamy clay soil(Eum-Orthic Anthrosol). The three-parameter model, i.e., Mezencev and Horton models can better describe the relationship between cumulative infiltration and infiltration time. In conclusion, biochar reduced the soil infiltration capacity of the aeolian sandy soil and increased that of the Eum-Orthic Anthrosol. | WANG Tongtong Catherine E STEWART MA Jiangbo ZHENG Jiyong ZHANG Xingchang | 2017 | Journal of Arid Land2017，9，5： | 9 |
| 4 | The water network in galectin-3 ligand binding site guides inhibitor design显示文摘显示出 -galactosides 的亲密关系的 Galectin-3 (Gal-3 ) 是癌症相关的蛋白质。因此,理解它的 ligand 绑定机制然后设计它的特定的禁止者是重要的。在 Gal-3 ligand 有约束力的地点的水分子的位置能被理想的禁止者的适当的化学的组代替,这被建议。然而,有乳糖的领域(CRD ) complexed 显示出的 Gal-3 糖类识别的报导结构水分子的数字是不同的,水放,这在 ligand 有约束力的地点是不一致的。这研究报导了四高分辨率(1.241.19 ?) 有乳糖的 Gal-3 CRD complexed 的结构,并且精确地由合并这些结构在 Gal-3 CRD ligand 有约束力的地点的水网络定位了 12 个保存的水分子。这些水分子也直接稳定 Gal-3 CRD 和乳糖的绑定,或在正确地方保持以前的水分子。特别地,浇分子 4 (W4 ) 它仅仅有水分子 5 的坐标(W5 ) 和水分子(W6 ) 6 在稳定半乳糖起一个关键作用残余。由所有残余的职务的三维的排列,另外, Gal-3 CRD 的 14 灵活部分被发现动态地在水晶的环境波动。 | Jiyong Su Tao Zhang Peiqi Wang Fengjian Liu Guihua Tai Yifa Zhou | 2015 | Acta Biochimica et Biophysica Sinica2015，47，3： | 4 |
| 5 | Identification of ssDNA aptamers specific to clinical isolates of Streptococcus mutans strains with different cariogenicity显示文摘链球菌 mutans,一个克积极的容许的厌氧的细菌,被认为是为牙齿的龋的一个主要 etiological 因素。在 thisstudy,从龋活跃、没有龋的个人的牙齿的瓷釉表面的匾为 S 被获得并且栽培。mutans 隔离。形态学检查,生物化学的描述,和聚合酶链反应被执行到识别。mutans。S 的 cariogenicity。从临床的标本孤立的 mutans 种类被测试细菌的 acidogenicity, aciduricity,细胞外的 polysaccharideproduction,和粘附能力评估。最后,减少性的 SELEX (由 exponentialenrichment 的 ligands 的系统的进化) 指向整个未经触动的房间的技术与 highcariogenicity 为对种类特定的 ssDNA aptamers 习惯于屏幕。在九轮减少性的 SELEX 以后,足够的水池丰富是由放射性的 isotopeanalysis 出现被完成。充实的水池随机被克隆并且定序,由联机的 MEME 和 RNA 结构软件 analysisof 列在后面序列。从流动 cytometry 的结果显示了那 aptamers H1, H16, H4, L1, L10,和 H19 能 discriminatehighly cariogenic S。mutans 紧张从糟糕, cariogenic 拉紧。在这些之中, Aptamer H19 与 cariogenic S 有最强壮的有约束力的能力。有 69.45 的一个分离常数的 mutans 紧张 ? 畣慬? 敭档湡獩獭漠 ??? 湡 ? 桴 ? 潰整瑮慩? 敮 ? 桴牥灡略楴? 瑳慲整楧獥潦 ? 桴 ? 牴慥浴湥 ? 景琠楨?湩敦瑣潩 | Wei Cui Jiaojiao Liu Donghua Su Danyang Hu Shuai Hou Tongnan Hu Jiyong Yang Yanping Luo Qing Xi Bingfeng Chu Chenglong Wang | 2016 | Acta Biochimica et Biophysica Sinica2016，48，6： | 3 |
| 6 | Study of frequency-shifted and re-scaling stochastic resonance and its application to fault diagnosis显示文摘 | Jiyong Tan Xuefeng Chen Junying Wang Huaxin Chen Hongrui Cao Yanyang Zi Zhengjia He | 2008 | Mechanical Systems and Signal Processing2008，，3： | 3 |
| 7 | Saturable plasmonic metasurfaces for laser mode locking显示文摘Metamaterials are artificial materials made of subwavelength elementary cells that give rise to unexpected wave properties that do not exist naturally.However,these properties are generally achieved due to 3D patterning,which is hardly feasible at short wavelengths in the visible and near-infrared regions targeted by most photonic applications.To overcome this limitation,metasurfaces,which are the 2D counterparts of metamaterials,have emerged as promising platforms that are compatible with planar nanotechnologies and thus mass production,which platforms the properties of a metamaterial into a 2D sheet.In the linear regime,wavefront manipulation for lensing,holography,and polarization control has been achieved recently.Interest in metasurfaces operating in the nonlinear regime has also increased due to the ability of metasurfaces to efficiently convert incident light into harmonic frequencies with unusual polarization properties.However,to date,the nonlinear absorption of metasurfaces has been mostly ignored.Here,we demonstrate that plasmonic metasurfaces behave as saturable absorbers with modulation performances superior to the modulation performance of other 2D materials and exhibit unusual polarimetric nonlinear transfer functions.We quantify the link between saturable absorption,the plasmonic resonances of the unit cell and their distribution in a 2D metasurface,and finally provide a practical implementation by integrating the metasurfaces into a fiber laser cavity operating in pulsed regimes driven by the metasurface properties.As such,this work provides new perspectives on ultrathin nonlinear saturable absorbers for applications where tunable nonlinear transfer functions are needed,such as in ultrafast lasers or neuromorphic circuits. | Jiyong Wang Aurelien Coillet Olivier Demichel Zhiqiang Wang Davi Rego Alexandre Bouhelier Philippe Grelu Benoit Cluzel | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 8 | Study of frequency-shifted and re-scaling stochastic resonance and its application to fault diagnosis显示文摘 | TAN Jiyong CHEN Xuefeng WANG Junying | 2009 | Mechanical Systems and Signal Processing2009，，23： | 1 |
| 9 | 显示文摘 | Wang Peng Wei Jiyong | 2007 | Materials Letters2007，61，： | 1 |
| 10 | Study of frequency-shifted and re-scaling stochastic resonance and its application to fault diagnosis 显示文摘 | TAN Jiyong CHEN Xuefeng WANG Junying | 2009 | Mechanical Systems and Signal Processing2009，23，3： | 1 |
| 11 | Non-destructive characterization of defects using a novel hybrid ultrasonic array sensor 显示文摘 | Wooh Shi-Chang Wang Jiyong | 2002 | NDT&E internarioal2002，35，： | 1 |
| 12 | A new 5G radio evolution towards 5G-Advanced显示文摘The evolution of the fifth-generation(5G)new radio(NR)has progressed swiftly since the third generation partnership project(3GPP)standardized the first NR version(Release 15)in mid-2018.Nowadays,the world’s leading carriers are competing to provide various commercial services over 5G networks.Looking ahead to 2025 and beyond,it is expected that over 6.5 million 5G base stations will be installed to offer services to over 58%of the world’s population via over 100 billion 5G connections.Following the rapid development of 5G,an increasing number of commercialization use cases will drive the 5G network to continuously improve performance and expand capabilities.Hence,it is the right time to consider a welldefined framework and standardization for 5G NR evolution(5G-Advanced)to support commercialization between 2025 and 2030.First,this study addresses the key driving forces,requirements,usage scenarios,and capabilities of 5G-Advanced;then,it highlights the main technological challenges and introduces the top 10 promising technological directions in detail.Finally,other fascinating technological directions in5G-Advanced are shortly mentioned. | Jiyong PANG Shaobo WANG Zhenfei TANG Yanmin QIN Xiaofeng TAO Xiaohu YOU Jinkang ZHU | 2022 | Science China(Information Sciences)2022，65，9： | 1 |
| 13 | Surfactants oil displacement system in high salinity formations:research and application 显示文摘 | Wang Yefei Wang Lushan Li Jiyong | 2001 | SPE 700472001，，： | 1 |
| 14 | Micro-scale opto-thermo-mechanical actuation in the dry adhesive regime显示文摘Realizing optical manipulation of microscopic objects is crucial in the research fields of life science,condensed matter physics,and physical chemistry.In non-liquid environments,this task is commonly regarded as difficult due to strong adhesive surface force(~µN)attached to solid interfaces that makes tiny optical driven force(~pN)insignificant.Here,by recognizing the microscopic interaction mechanism between friction force—the parallel component of surface force on a contact surface—and thermoelastic waves induced by pulsed optical absorption,we establish a general principle enabling the actuation of micro-objects on dry frictional surfaces based on the opto-thermo-mechanical effects.Theoretically,we predict that nanosecond pulsed optical absorption with mW-scale peak power is sufficient to tameµN-scale friction force.Experimentally,we demonstrate the two-dimensional spiral motion of gold plates on micro-fibers driven by nanosecond laser pulses,and reveal the rules of motion control.Our results pave the way for the future development of micro-scale actuators in non-liquid environments. | Weiwei Tang Wei Lyu Jinsheng Lu Fengjiang Liu Jiyong Wang Wei Yan Min Qiu | 2021 | Light(Science & Applications)2021，10，10： | 1 |
| 15 | Study of frequency-shifted and re-scaling stochastic resonance and its application to fault diagnosis 显示文摘 | TAN Jiyong CHEN Xuefeng WANG Junying | 2009 | Mechanical Systems and Signal Processing2009，，23： | 1 |
| 16 | A Solar Radio Spectrometer at 5.2–7.6?GHz显示文摘 | Huirong Ji Qijun Fu Yuying Liu Congling Cheng Zhijun Chen Yihua Yan Leping Zheng Zongjun Ning Chengmin Tan Debang Lao Shuke Li Jiyong Gao Zhiqiang Wang Minhong Yu | 2003 | Solar Physics2003，，2： | 1 |
| 17 | Nondestructive characterization of defects using a novel hybrid ultrasonic array sensor 显示文摘 | Wooh S C Wang Jiyong | 2002 | Nondestructive Evaluation International2002，35，3： | 1 |
| 18 | Study of frequency-shifted and re-scaling stochasticresonance and its application to fault diagnosis显示文摘 | TAN Jiyong CHEN Xuefeng WANG Junying | 2009 | Mechanical Systems and Signal Processing2009，23，3： | 1 |
| 19 | Reservoir Characteristics of Fine-grained Sedimentary Rocks in Saline Lakes in the Cenozoic Upper Ganchaigou Formation,Southwestern Qaidam Basin,NW China显示文摘Cenozoic fine-grained sedimentary rocks in the southwestern Qaidam Basin,as typical salinized lacustrine sediments,are significantly different from those in other freshwater lakes under the impact of the high salinity in the lake.Many fine-grained sedimentary rock samples were selected from the lower member of Neogene(N_(1))in the Gaskule Oilfield,Qaidam Basin,northwest China,with the aim to analyze and test their petrology,pore structure,and organic geochemical characteristics and determine its genesis and geological significance.Based on previous results,a new genesis of mixed sedimentary rocks is proposed.The Cenozoic lacustrine fine-grained sedimentary rocks in SW Qaidam Basin belong to mixed sedimentary rocks,which can be divided into three types,including carbonate and terrigenous clastic-bearing mudstone,carbonate-bearing to terrigenous clastic mixed sedimentary rocks,and carbonate-terrigenous clastic mixed sedimentary rocks.The geneses of mixing are quite different from that of mixed marine rocks.According to the sedimentary characteristics of the salinized lakes,three new geneses of mixed deposits are proposed:syn-sedimentary mixing,varve interbedded mixing,and biogenic mixing.The reservoir spaces of the Cenozoic lacustrine fine-grained sedimentary rocks in SW Qaidam Basin include residual intergranular pores,intercrystalline pores,microfractures,and minor dissolved pores.The reservoirs have super-low porosity and ultra-low permeability,with a porosity of 1.82%-21.04%,averaging 7.71%,and permeability of(0.0028-254.86)×10^(−3)μm^(2),averaging 2.82×10^(−3)μm^(2).The test results of total organic carbon(TOC)content show that the highest content of organic carbon reached 1.41%,and those of vitrinite reflectance show that Ro ranges from 0.525%-0.824%,with an average of 0.806%.The organic geochemical characteristics show that the fine-grained mixed sedimentary rocks of SW Qaidam Basin have the potential for self-generation and self-storage.As an unconventional reservoir,it has potential industrial value.This is the first study of fine-grained sedimentary rocks in the Qaidam Basin,which offers certain theoretical and practical values. | SHENG Jun LIU Jincheng LI Yunlong ZOU Haiyan LONG Anlin WANG Lin LI Jiyong QI Qingshan YANG Xiaojing LI Yanan | 2022 | Acta Geologica Sinica(English Edition)2022，96，3： | 1 |
| 20 | Expression for peroxisome proliferator-activated receptor gamma in pituitary adenomas 38 cases for semi-quantitative immunohistochemical analysis显示文摘BACKGROUND: It has been reported that peroxisome proliferator-activated receptor γ(PPARγ) is highly expressed in lung cancer, colon cancer, and gastric cancer, as well as other tumors. OBJECTIVE: To study expression of PPARγin pituitary adenomas and analyze the role of PPARγin hormonal typing of pituitary adenomas. DESIGN, TIME AND SETTING: Semi-quantitative immunohistochemistry of pathological specimens. The experiment was conducted at the Department of Neurosurgery, Wuxi Second Hospital Affiliated to Nanjing Medical University between January 2002 and May 2005. MATERIALS: Surgical resection samples of pituitary adenomas from 38 cases (18 male and 20 female) were analyzed. Eight cases were determined to be invasive pituitary adenomas and 30 cases were non-invasive pituitary adenomas. Hormonal classification of the types of pituitary adenomas revealed somatotrophic adenomas in six cases, corticotrophic adenoma in five cases, prolactinomas in 13 cases, multi-hormone secreting adenomas in six cases, and eight cases of adenoma without altered endocrine function. Five autopsy specimens were collected during the same period from patients of matching age that died from unrelated diseases and were included as normal anterior pituitary controls. METHODS: Cell counts for positive immunohistochemical signals were recorded from histopathological sections. The percentage of positive cells was reported as a semi-quantitative analysis. MAIN OUTCOME MEASURES: The rate of PPARγpositive cells in different types of adenoma was based on hormonal levels and invasiveness of pituitary tumor cells. RESULTS: All tumor biopsies were determined to express PPARγ The rate of PPARγ-positive cells ranged between 8%-65% in the pituitary adenomas. According to hormonal type, PPARγexpression did not vary between the groups. In addition, there was no significant difference in PPARγexpression between the non-invasive and invasive pituitary adenomas. CONCLUSIONS: Human pituitary adenomas express PPARγ, and this expression is unrelated to hormonal type and invasiveness. | Xiaojie Lu Kailai Chen Weiyang Ji Qing Wang Bing Li Jiang'an Li Jiyong Sun | 2008 | Neural Regeneration Research2008，3，7： | 1 |
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