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| 1 | New magnifying endoscopic classification for superficial esophageal squamous cell carcinoma显示文摘AIM To assess the accuracy of a new magnifying endoscopy(ME)classification for predicting depth of invasion of superficial esophageal squamous cell carcinoma(SESCC).METHODS This study included a total of 70 lesions in 69 patients with SESCC who underwent ME with narrow-band imaging(ME-NBI)before resection from August 2010 to July 2016.Accuracy of ME-NBI for predicting depth of invasion of SESCC was analyzed by using a new ME classification proposed by the Japan Esophageal Society(JES),and interobserver agreement was assessed.RESULTS Overall accuracy of ME-NBI for estimating depth of invasion of SESCC was 78.6%.Sensitivity and specificity of type B1 for tumors limited to the epithelial layer(m1)or invading into the lamina propria(m2)were 71.4%and 100%,respectively.Sensitivity and specificity of type B2 for tumors invading into the muscularis mucosa(m3)or superficial submucosa(≤200μm,sm1)were94.4%and 73.1%,respectively,while those of type B3for tumors invading into the deep submucosa(>200μm,sm2)were 75.0%and 97.8%,respectively.Interobserver agreement was excellent(κ=0.86,95%CI:0.76-0.95).CONCLUSION The recently developed JES ME classification is useful for predicting depth of invasion of SESCC,with reliable interobserver agreement. | Su Jin Kim Gwang Ha Kim Moon Won Lee Hye Kyung Jeon Dong Hoon Baek Bong Eun Lee Geun Am Song | 2017 | World Journal of Gastroenterology2017，23，24： | 13 |
| 2 | Significant risk and associated factors of active tuberculosis infection in Korean patients with inflammatory bowel disease using anti-TNF agents显示文摘AIM:To evaluate the incidence and risk factors of Korean tuberculosis(TB) infection in patients with inflammatory bowel disease(IBD) undergoing anti-TNF treatment.METHODS:The data of IBD patients treated with anti-TNFs in 13 tertiary referral hospitals located in the southeastern region of Korea were collected retrospectively.They failed to show response or were intolerant to conventional treatments,including steroids or immunomodulators.Screening measures for latent TB infection(LTBI)and the incidence and risk factors ofactive TB infection after treatment with anti-TNFs were identified.RESULTS:Overall,376 IBD patients treated with antiTNF agents were recruited(male 255,mean age of anti-TNF therapy 32.5±13.0 years);277 had Crohn’s disease,99 had ulcerative colitis,294 used infliximab,and 82 used adalimumab.Before anti-TNF treatment,screening tests for LTBI including an interferon gamma release assay or a tuberculin skin test were performed in 82.2%of patients.Thirty patients(8%)had LTBI.Sixteen cases of active TB infection including one TB-related mortality occurred during 801 personyears(PY)follow-up(1997.4 cases per 100000 PY)after anti-TNF treatment.LTBI(OR=5.76,95%CI:1.57-21.20,P=0.008)and WBC count<5000 mm3(OR=4.5,95%CI:1.51-13.44,P=0.007)during follow-up were identified as independently associated risk factors.CONCLUSION:Anti-TNFs significantly increase the risk of TB infection in Korean patients with IBD.The considerable burden of TB and marked immunosuppression might be attributed to this risk. | Eun Soo Kim Geun Am Song Kwang Bum Cho Kyung Sik Park Kyeong Ok Kim Byung Ik Jang Eun Young Kim Seong Woo Jeon Hyun Seok Lee Chang Heon Yang Yong Kook Lee Dong Wook Lee Sung Kook Kim Tae Oh Kim Jonghun Lee Hyung Wook Kim Sam Ryong Jee Seun Ja Park Hyun Jin Kim | 2015 | World Journal of Gastroenterology2015，21，11： | 5 |
| 3 | Is ineffective esophageal motility associated with gastropharyngeal reflux disease?显示文摘AIM: To evaluate the association between ineffective esophageal motility (IEM) and gastropharyngeal reflux disease (GPRD) in patients who underwent ambulatory 24-h dual-probe pH monitoring for the evaluation of supraesophageal symptoms. METHODS: A total of 632 patients who underwent endoscopy,esophageal manometry and ambulatory 24-h dual-pH monitoring due to supraesophageal symptoms (e.g. globus,hoarseness,or cough) were enrolled. Of them,we selected the patients who had normal esophageal motility and IEM. The endoscopy and ambulatory pH monitoring findings were compared between the two groups. RESULTS: A total of 264 patients with normal esophageal motility and 195 patients with the diagnosis of IEM were included in this study. There was no difference in the frequency of reflux esophagitis and hiatal hernia between the two groups. All the variables showing gastroesophageal reflux and gastropharyngeal reflux were not different between the two groups. The frequency of GERD and GPRD,as defined by ambulatory pH monitoring,was not different between the two groups. CONCLUSION: There was no association between IEM and GPRD as well as between IEM and GERD. IEM alone cannot be considered as a definitive marker for reflux disease. | Kyung Yup Kim Gwang Ha Kim Dong Uk Kim Soo Geun Wang Byung Joo Lee Jin Choon Lee Do Youn Park Geun Am Song | 2008 | World Journal of Gastroenterology2008，14，39： | 3 |
| 4 | The value of tumor markers in evaluating chemotherapy response and prognosis in Chinese patients with advanced non-small cell lung cancer显示文摘 | Jin B Huang AM Zhong RB | | 0，，06： | 1 |
| 5 | The endothelial-cell-derived secreted factor Egfl7regulates vas-cular tube formation显示文摘 | Parker LH Schmidt M Jin SW Gray AM Beis D Pham T | 2004 | Nature2004，428，6984： | 1 |
| 6 | Cytoprotection of Heme Oxygenase-1/Carbon Monoxide in Lung Injury 显示文摘 | Jin Y Choi AM | 2005 | Proc Am Thorac Soc2005，2，3： | 1 |
| 7 | The endothelial-cell-derived secreted factor Egfl7 regulatesvascular tube formation显示文摘 | Parker LH Schmidt M Jin SW Gray AM Beis D Pham T etal | 2004 | Nature2004，428，6984： | 1 |
| 8 | Mechanism of positive allosteric modulators acting on AMPA receptors 显示文摘 | Jin R Clark S Weeks AM | 2005 | J Neurosci2005，25，39： | 1 |
| 9 | Mechanical properties andin vivo healing evaluation of a novel Centella asiatica-loadedhydrocolloid wound dressing显示文摘 | Jin SG Kim KS Yousaf AM | 2015 | Int J Pharm2015，490，12： | 1 |
| 10 | Heterosynaptic molecular dynamics: locally induced propagating synaptic accumulation of CaM kinase II显示文摘 | Rose J Jin SX Craig AM | 2009 | Neuron2009，61，3： | 1 |
| 11 | The costimulatory molecule ICOS regulates the expression of c-Mar and IL-21 in the develop- ment of follicular T helper cells and TH-17 cells 显示文摘 | Bauquet AT Jin H Paterson AM et at | 2009 | Nat Immu- nol2009，10，2： | 1 |
| 12 | Finite element analysis of posterior cervical fixation 显示文摘 | Duan Y Wang HH Jin AM | 2015 | Orthop Traumatol-Sur2015，101，： | 1 |
| 13 | The reason analysis and therapeuticstrategy for bad therapeutic effect after lumbar disc herniation oper-ation 显示文摘 | Jin AM Yao WT Zhang H | 2003 | Zhonghua Gu Ke Za Zhi2003，23，11： | 1 |
| 14 | Expression of the B subunit of Escherichia coli heat-labile enterotoxin as a fusion protein in transgenic tomato显示文摘 | Walmsley AM Alvarez ML Jin Y | 2003 | Plant Cell Rep2003，21，10： | 1 |
| 15 | The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper ceils and TH-17 cells 显示文摘 | Bauquet AT Jin H Paterson AM | 2009 | Nat Immunol2009，10，： | 1 |
| 16 | The value of tumor markers in evaluating chemotherapy response and prognosis in Chinese patients with advanced non-small cell lung cancer显示文摘 | Jin B Huang AM Zhong RB | | 0，，06： | 1 |
| 17 | Autophagic proteins : new facets of the oxygen paradox 显示文摘 | Jin Y Tanaka A Choi AM | 2012 | Autophagy2012，8，3： | 1 |
| 18 | A visualization system for space-time and multivariate patterns (VIS-STAMP)显示文摘 | GUO Dian-sheng CHEN Jin MACEACHRENn AM | 2006 | IEEE Trans on Visualization and Computer Graphics2006，12，6： | 1 |
| 19 | Uremic cardiac hyper-trophy is reversed by rapamycin hut not by lowering of blood pressure显示文摘 | Siedlecki AM Jin X Muslin AJ | 2009 | Kidney Int2009，75，： | 1 |
| 20 | Endoscopic sphincterotomy plus large-balloon dilation versus endoscopic sphincterotomy for removal of bile-duct stones <ce:link locator='fx1'/>显示文摘 | Jeung Ho Heo Dae Hwan Kang Hyo Jin Jung Dae Sik Kwon Jin Kwang An Bo Suk Kim Kyung Duk Suh Sang Yong Lee Joo Ho Lee Gwang Ha Kim Tae Oh Kim Jeong Heo Geun Am Song Mong Cho | 2007 | Gastrointestinal Endoscopy2007，，4： | 1 |
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