|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Significant risk and associated factors of active tuberculosis infection in Korean patients with inflammatory bowel disease using anti-TNF agents显示文摘AIM:To evaluate the incidence and risk factors of Korean tuberculosis(TB) infection in patients with inflammatory bowel disease(IBD) undergoing anti-TNF treatment.METHODS:The data of IBD patients treated with anti-TNFs in 13 tertiary referral hospitals located in the southeastern region of Korea were collected retrospectively.They failed to show response or were intolerant to conventional treatments,including steroids or immunomodulators.Screening measures for latent TB infection(LTBI)and the incidence and risk factors ofactive TB infection after treatment with anti-TNFs were identified.RESULTS:Overall,376 IBD patients treated with antiTNF agents were recruited(male 255,mean age of anti-TNF therapy 32.5±13.0 years);277 had Crohn’s disease,99 had ulcerative colitis,294 used infliximab,and 82 used adalimumab.Before anti-TNF treatment,screening tests for LTBI including an interferon gamma release assay or a tuberculin skin test were performed in 82.2%of patients.Thirty patients(8%)had LTBI.Sixteen cases of active TB infection including one TB-related mortality occurred during 801 personyears(PY)follow-up(1997.4 cases per 100000 PY)after anti-TNF treatment.LTBI(OR=5.76,95%CI:1.57-21.20,P=0.008)and WBC count<5000 mm3(OR=4.5,95%CI:1.51-13.44,P=0.007)during follow-up were identified as independently associated risk factors.CONCLUSION:Anti-TNFs significantly increase the risk of TB infection in Korean patients with IBD.The considerable burden of TB and marked immunosuppression might be attributed to this risk. | Eun Soo Kim Geun Am Song Kwang Bum Cho Kyung Sik Park Kyeong Ok Kim Byung Ik Jang Eun Young Kim Seong Woo Jeon Hyun Seok Lee Chang Heon Yang Yong Kook Lee Dong Wook Lee Sung Kook Kim Tae Oh Kim Jonghun Lee Hyung Wook Kim Sam Ryong Jee Seun Ja Park Hyun Jin Kim | 2015 | World Journal of Gastroenterology2015，21，11： | 5 |
| 2 | Numerical simulation for dendrite growth in directional solidification using LBM-CA(cellular automata)coupled method显示文摘To predict the dendrite morphology and microstructure evolution in the solidification of molten metal,numerically,lattice Boltzmann method(LBM)-cellular automata(CA)model has been developed by integrating the LBM to solve the mass transport by diffusion and convection during solidification and the CA to determine the phase transformation with respect to the solid fraction based on the local equilibrium theory.It is successfully validated with analytic solutions such as Lipton-Glicksman-Kurz(LGK)model in static melt,and Oseen-Ivantsov solution under the fluid flow conditions in terms of tip radius and velocity of the dendrite growth.The proposed LBM-CA model does not only describe different types of dendrite formations with respect to various solidification conditions such as temperature gradient and growth rate,but also predict the primary dendrite arm spacing(PDAS)and the secondary dendrite arm spacing(SDAS),quantitatively,in directional solidification(DS)experiment with Ni-based superalloy. | Wonjoo Lee Yuhyeong Jeong Jae-Wook Lee Howon Lee Seong-hoon Kang Young-Min Kim Jonghun Yoon | 2020 | Journal of Materials Science & Technology2020，47，14： | 3 |
| 3 | Impact of Viral Hepatitis on Outcomes after Liver Resection for Hepatocellular Carcinoma: Results from a North American Center显示文摘 | Jonghun J. Lee Peter T. W. Kim Sandra Fischer Scott Fung Steven Gallinger Ian McGilvray Carol-anne Moulton Alice C. Wei Paul D. Greig Sean P. Cleary | 2014 | Annals of Surgical Oncology2014，，8： | 1 |
| 4 | Dynamic deformation behavior and microstructural evolution during high-speed rolling of Mg alloy having non-basal texture显示文摘The dynamic deformation behaviors and resultant microstructural variations during high-speed rolling(HSR) of a Mg alloy with a non-basal texture are investigated. To this end, AZ31 alloy samples in which the basal poles of most grains are predominantly aligned parallel to the transverse direction(TD) are subjected to hot rolling with different reductions at a rolling speed of 470 m/min. The initial grains with a TD texture are favorable for {10–12} twinning under compression along the normal direction(ND); as a result, {10–12} twins are extensively formed in the material during HSR, and this consequently results in a drastic evolution of texture from the TD texture to the ND texture and a reduction in the grain size. After the initial grains are completely twinned by the {10–12} twinning mechanism, {10–11} contraction twins and {10–11}-{10–12} double twins are formed in the {10–12} twinned grains by further deformation.Since the contraction twins and double twins have crystallographic orientations that are favorable for basal slip during HSR, dislocations easily accumulate in these twins and fine recrystallized grains nucleate in the twins to reduce the increased internal strain energy. Until a rolling reduction of 20%, {10–12}twinning is the main mechanism governing the microstructural change during HSR, and subsequently,the microstructural evolution is dominated by the formation of contraction twins and double twins and the dynamic recrystallization in these twins. With an increase in the rolling reduction, the average grain size and internal strain energy of the high-speed-rolled(HSRed) samples decrease and the basal texture evolves from the TD texture to the ND texture more effectively. As a result, the 80% HSRed sample, which is subjected to a large strain at a high strain rate in a single rolling pass, exhibits a fully recrystallized microstructure consisting of equiaxed fine grains and has an ND basal texture without a TD texture component. | Sang-Hoon Kim Jeong Hun Lee Chong Soo Lee Jonghun Yoon Sung Hyuk Park | 2019 | Journal of Materials Science & Technology2019，35，4： | 1 |
| 5 | Topic based photo set retrieval using user annotated tags显示文摘 | Lee Sangjin Park Jonghun | 2013 | Multimedia Tools and Applications2013，64，1： | 1 |
| 6 | Micro genetic algorithm based optimal gate positioning in injection molding design显示文摘 | Jongsoo Lee Jonghun Kim | 2007 | Journal of Mechanical Science and Technology2007，，5： | 1 |
| 7 | Micro genetic algorithm based optimal gate position in injection molding design显示文摘 | Jongsoo Lee Jonghun Kim | 2007 | Journal of Mechanical Science and Technology2007，21，2007： | 1 |
| 8 | Detection of chemicals in water using a three-dimensional graphene porous structure as liquid-vapor separation filter显示文摘在这研究,我们报导利用一三维(3D ) 多孔的 graphene 当堵住液体化学药品和水时,作为液体蒸汽分离过滤器组织,它允许化学蒸汽的经过。从区域被要求避免反常晶体管特征的半导体的察觉到的液体化学药品和水的阻塞。以便给予 omniphobic 特征,一(heptadecafluoro-1,1,2,2-tetrahydrodecyl ) trichlorosilane (HDF-S ) 自我装配的单层在 3D 的表面上是涂的多孔的 graphene 结构。水里的化学代理人的集中能被在 HDF-S 自我装配的 3D graphene 结构盖住的氧化物 nanowire 晶体管在阀值电压观察移动一致地检测。建议监视方法被期望由提供察觉到性能的一个马厩在不同环境为申请提供工具。 | Taekyung Lim Jaejun Lee Jonghun Lee Sanghyun Ju | 2017 | Nano Research2017，10，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员