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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Investigation and comparison of spray characteristics of pressure-swirl atomizers for a small-sized aircraft turbine engine 显示文摘 | Durdina L Jedelsky J Jicha M | 2014 | Intemational Journal of Heat and MassTransfer2014，78，： | 1 |
| 3 | Development of an effervescent atomizer for industrial burners 显示文摘 | Jedelsky J Jicha M Slama J | 2009 | Energy Fuels2009，23，12： | 1 |
| 4 | APOE-2 and APOE e4 Correlate with Increased Amyloid Accumulation in Cerebral Vaseu- fature显示文摘 | Nelson P T Pious N M Jicha G A | 2013 | J Neuropathol Exp Neurol2013，72，7： | 1 |
| 5 | Eulerian-Lagrangian model for traffic dynamics and its impact on operational ventilation of road tunnels显示文摘 | Katolicy J Jicha M | 2005 | Journal of Wind Engineering and Industrial Aerodynamics2005，93，1： | 1 |
| 6 | Aberrant expression of mitotic Cdc2/Cyclin B kinase in degenerating neurons of Alzheimer' s disease brains显示文摘 | Vincent I Jicha G Rosado M | 1997 | J Neurosic1997，17，： | 1 |
| 7 | Algal assemblages for large river monitoring: comparison among biovolume, absolute and relative abundance metrics显示文摘 | Reavie E D Jicha T M Angradi T R | 2010 | Ecological Indicators2010，10，2： | 1 |
| 8 | Aberrant expression of mitotic cdc2/ cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain 显示文摘 | Vincent I Jicha G Rosado M | 1997 | Neuroscience1997，17，10： | 1 |
| 9 | Development of an effervescent atomizer for industrial burners显示文摘 | Jedelsky J Jicha M Slama J | 2009 | Energy Fuels2009，23，12： | 1 |
| 10 | Enhanced tumor growth of both primary and established human and murine tumor cells in athymic mice after coinjection with Matrigel显示文摘 | Fridman R Kibbey MC Royce LS Zain M Sweeney M Jicha DL | 1991 | J Natl Cancer Inst1991，83，： | 1 |
| 11 | Aberrant expression of mitoticc dc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain显示文摘 | Vincent 1 Jicha G Rosario M | 1997 | J Neurosci1997，17，10： | 1 |
| 12 | Impact of air distribution system on quality of ventilation in small aircraft cabin 显示文摘 | FISER J JICHA M | 2013 | Build Environ2013，69，11： | 1 |
| 13 | Development of an efferves- cent atomizer for industrial burners显示文摘 | Jedelsky J Jicha M Slama J | 2009 | Energy Fuels2009，23，： | 1 |
| 14 | Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain显示文摘 | Jicha G Rosado M | 1997 | J Neurosci1997，17，10： | 1 |
| 15 | Aberrant expression of mi- totic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain显示文摘 | Vincent I Jicha G Rosado M | 1997 | J Neurosci1997，17，10： | 1 |
| 16 | Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain显示文摘 | Vincent I Jicha G Rosado M | 1997 | J Neurosci1997，17，10： | 1 |
| 17 | Influence of the lime slurry droplet spectrum on the efficiency of semi-dry flue gas desulfurization显示文摘 | Katolicky J Jicha M | 2013 | Chem Eng Technol2013，36，1： | 1 |
| 18 | APOE-epsi- lon2 and APOE-epsilon4 correlate with increased amyloid accumulation in cerebral vasculature 显示文摘 | Nelson P T Pious N M Jicha G A | 2013 | J Neuropathol Exp Neurol2013，72，7： | 1 |
| 19 | Dispersion of pollutants in street canyon under traffic induced flow and turbulence显示文摘 | JICHA M POSPISIL J KATOLICKY J | | 0，，1： | 1 |
| 20 | Eulerian-Lagrangian model for traffic dynamics and its impact on operational ventilation of road tunnels显示文摘 | KATOLICKY J JICHA M | | 0，，： | 1 |
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