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| 1 | Protective effects of Yindanxinnaotong capsule in a rat model of myocardial ischemia/reperfusion injury显示文摘OBJECTIVE: To investigate the effects of Yindanxinnaotong capsule(YDXNTC) and main components compatibility and ratios on myocardium against ischemia/reperfusion injury and the effect's underlying mechanism.METHODS: Myocardial ischemia/reperfusion injury(MIRI) was induced by ischemia for 30 min and reperfusion for 30 min. Electrocardiogram data and coronary flow were recorded, and superoxide dismutase(SOD), malondialdehyde(MDA), lactate dehydrogenase, creatine kinase-MB, cardiac troponin T and I(cT nT, cT n I) and interleukin-1β, interleukin-8,interleukin-18(IL-1β, IL-8, IL-18) in myocardium were measured. Hypoxia/reoxygenation and hydrogen peroxide(H2O2) injury were induced by hypoxia for 3 h/reoxygenation for 2 h, and 100 μM H2O2 for 1 h, respectively, in vitro rat myocardial cells(H9c2). Cell viability, SOD, MDA, cT nT and inflamma-tory factors(IL-1β, IL-8 and IL-18) were determined,and Toll-like receptor 4(TLR-4) expression was measured by western blotting.RESULTS: In the isolated heart experiment, elevated heart function, coronary flow and SOD levels,and decreased MDA levels and inflammatory factors were noted in the YDXNTC, main components and main components compatibility groups. Ventricular tachycardia/ventricular fibrillation occurrence decreased in the ginkgo biloba extract(GBE),and GBE and salvia miltiorrhiza ethanol extract compatibility(SM-E, GSEC) groups. Lactic dehydrogenase levels decreased in the YDXNTC and aqueous extract of salvia miltiorrhiza(SM-H) groups. Creatine kinase-MB decreased with GBE, SM-E, SM-H and GSEC treatment, and cT n I and cT nT levels decreased with GSEC. In the in vitro cell study,YDXNTC and main components ratios improved cell viability and SOD levels, and suppressed MDA,cT nT and inflammatory factors. TLR-4 expression was down-regulated.CONCLUSION: YDXNTC and main components compatibility showed protective effects on MIRI in this rat model and in vitro study. Regulating the Toll-like receptor signaling pathway may affect the mechanism. | Wandan Wang Lan Wang Hongjun Yang Jianlu Wang Xiaojie Yin Haiyu Xu Long Cheng Rixin Liang | 2014 | Journal of Traditional Chinese Medicine2014，34，6： | 22 |
| 2 | Mechanical and Wear Properties of Nanostructured Surface Layer in Iron Induced by Surface Mechanical Attrition Treatment显示文摘A porosity-free and contamination-free surface layer with grain sizes ranging from nanometer to micrometer in Fe samples was obtained by surface mechanical attrition treatment (SMAT) technique. Mechanical and wear properties of the surface layer in the SMATed and annealed Fe samples were measured by means of nanoindentation and nanoscratch tests, respectively. Experimental results showed that the hardness of the surface layer in the SMATed Fe sample increased evidently due to the grain refinement. The elastic noduli of the surface layers in the SMATed and annealed Fe samples were unchanged, independent of grain size in the present grain size regime. Compared with the original Fe sample, the wear resistance enhanced and the coefficient of friction decreased in the surface layer of the SMATed Fe sample. | NairongTAO WeipingTONG ZhenboWANG WeiWANG ManlingSUI JianLU KeLU | 2003 | Journal of Materials Science & Technology2003，19，6： | 17 |
| 3 | Gaseous Nitriding Process of Surface Nanocrystallized (SNCed) Steel显示文摘The behavior of gaseous nitriding on the surface nanocrystallized (SNCed) steel was investigated. The mild steel discs were SNCed on one side by using the method of ultrasonic shot peening. The opposite side of the discs maintained the original coarse-grained condition. The gaseous nitriding was subsequently carried out at three different temperatures:460, 500 and 560℃. The compound layer growth and diffusion behavior were then studied. It was revealed that SNC pretreatment greatly enhances both diffusion coefficient D and surface reaction rate. As a result, nitriding time could be reduced to the half. It was also found that the growth of compound layer with nitriding time conformed with parabolic relationship from the start of nitriding process in the SNCed samples. | DuohuiBEI JianLUE 等 | 2002 | Journal of Materials Science & Technology2002，18，6： | 9 |
| 4 | Anti-breast cancer effects and mechanisms of Xihuang pill on human breast cancer cell lines显示文摘OBJECTIVE: To investigate the anti-breast cancer(BC) effects and mechanisms of action of Xihuang pill(XHP) by conducting in vitro experiments on human BC cell lines. METHODS: Two human BC cell lines(MCF-7 and MDAMB231) were cultured and treated with XHP. Cell viability was detected using the 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide(MTT) assay. Flow cytometry was used to measure the cell cycle and apoptosis. The cell cycle was analyzed with propidium iodide staining. Apoptosis was evaluated using the Annexin V-fluorescein isothiocyanate/propidium iodide method. Western blotting was used to analyze the expression of estrogen receptor(ER)-α and ER-β.RESULTS: XHP had growth-inhibitory effects on MCF-7 and MDA-MB231 cells with a half-maximal inhibitory concentration(IC50) of 10.14 mg/mL(MCF-7) and 8.98 mg/mL(MDA-MB231). Apoptosis was induced to some extent. Certain changes in the ER were caused. Upregulation of ER-α protein was found in MCF-7 cells. ER-β expression in MDA-MB231 cells was increased. Cell-cycle arrest was not observed in the two BC cell lines. ER-β expression in MCF-7 cells was unchanged. No ER-α expression was shown in MDA-MB231 cells. CONCLUSION: These data suggest that XHP can affect cell viability and cause apoptosis, but that the cell cycle is not blocked. XHP has a certain impact on ER expression, but its mechanisms of action of anti-BC effects may not be due to regulation of ER expression. | Guofeng Pan Wandan Wang Lan Wang Fangbo Zhang Xiaojie Yin Jianlu Wang Rixin Liang | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 8 |
| 5 | Structural and Mechanical Characterization ofAtrina Pectinata and Freshwater Mussel Shells显示文摘 | Jianlu Lv Yonggang Jiang Deyuan Zhang | 2015 | Journal of Bionic Engineering2015，12，2： | 7 |
| 6 | Characterization of atomic defects on the photoluminescence in two-dimensional materials using transmission electron microscope显示文摘Two-dimensional material(2D)that possesses atomic thin geometry and remarkable properties is a star material for the fundamental researches and advanced applications.Defects in 2D materials are critical and fundamental to understand the chemical,physical,and optical properties.Photoluminescence arises in 2D materials owing to various physical phenomena including activator/dopant-induced luminescence and defect-related emissions,and so forth.With the advanced transmission electron microscopy(TEM)technologies,such as aberration correction and low voltage technologies,the morphology,chemical compositions and electronic structures of defects in 2D material could be directly characterized at the atomic scale.In this review,we introduce the applications of state-of-the-art TEM technologies on the studies of the role of atomic defects in the photoluminescence characteristics in 2D material.The challenges in spatial and time resolution are also discussed.It is proved that TEM is a powerful tool to pinpoint the relationship between the defects and the photoluminescence characteristics. | Jiayan Zhang Ye Yu Peng Wang Chen Luo Xing Wu Ziqi Sun Jianlu Wang Wei Da Hu Guozhen Shen | 2019 | InfoMat2019，1，1： | 6 |
| 7 | Large-area high quality PtSe2 thin film with versatile polarity显示文摘Two-dimensional(2D)materials have attracted increasing attention for their outstanding structural and electrical properties.However,for mass-production of field effect transistors(FETs)and potential applications in integrated circuits,large-area and uniform 2D thin films with high mobility,large on-off ratio,and desired polarity are needed to synthesize firstly.Here,a transfer-free growth method for platinum diselenide(PtSe2)films has been developed.The PtSe2 films have been synthesized with various thicknesses in centimeter-sized scale.Typical FET made from a few layer PtSe2 show p-type unipolar,with a high field-effect hole mobility of 6.2 cm^(2) V^(−1) s^(−1) and an on-off ratio of 5×10^(3).The versatile semimetal-unipolar-ambipolar transition in synthesized PtSe2 films is also firstly observed as the thickness thinning.This work realizes the large-scale preparation of PtSe2 with prominent electrical properties and provides a new strategy for polarity's modulation. | Wei Jiang Xudong Wang Yan Chen Guangjian Wu Kun Ba Ningning Xuan Yangye Sun Peng Gong Jingxian Bao Hong Shen Tie Lin Xiangjian Meng Jianlu Wang Zhengzong Sun | 2019 | InfoMat2019，1，2： | 5 |
| 8 | 利用纳米压入加载曲线确定金属薄膜的屈服强度和硬化指数 Ⅱ.实验及验证显示文摘通过比较实测与计算所得整体材料纳米压入加载曲线及Berkovich压头的面积函数,对已建立的Berkovich压头绝对钝化量的确定方法进行了实验验证在此基础上,测定了蒸发恢制在Si单晶上三种不同膜厚Al膜的屈服强度和硬化指数,并与拉伸分离法获得的结果进行了比较结果表明,利用纳米压入加载曲线确定陶瓷基体上金属薄膜基本力学性能的方法是可行的. | 马德军 徐可为 何家文 JianLU | 1999 | 金属学报1999，35，10： | 5 |
| 9 | Microstructure-dependent oxidation behavior of Ni-Al single-crystal alloys显示文摘The effect of theγ+γtwo-phase structure on the oxidation behaviors of Ni-Al single-crystal alloys at 650℃was investigated by scanning electron microscopy,transmission electron microscopy,atomic force microscopy,X-ray diffraction and Auger electron spectroscopy.In the initial oxidation stage,the oxidation behavior is primarily determined by the growth pattern of oxides in theγchannel.The outward convex NiO was formed in unprotected wideγchannels.And Ni-Al spinel oxide provides a great number of short-circuit paths,accelerating the inward diffusion of oxygen and outward diffusion of Ni.In the late stage of oxidation,the elongated internal oxide in the largeγphase contributes to the diffusion of oxygen along the oxide/metal interface.Consequently,the Ni-Al single-crystal alloy with wideγchannels and largeγprecipitates exhibited poor oxidation performance. | Jianlu Pei Yefan Li Chong Li Zumin Wang Yongchang Liu Huijun Li | 2020 | Journal of Materials Science & Technology2020，52，17： | 4 |
| 10 | Materials Experiment on Tiangong-2 Space Laboratory显示文摘During the China's Tiangong-2(TG-2) flight mission, the experiments of 18 kinds of material samples were conducted in space by using a Multiple Materials Processing Furnace(MMPF) mounted in the orbital module of the TG-2 space laboratory. After the experiments of 12 kinds of samples of the first and second batches were completed successfully, astronauts packed and brought them back to the ground by ShenzhouII spacecraft. By studying processing and formation on semiconductor and optoelectronics materials, metal alloys and metastable materials, functional single-crystal, micro-and nano-composite materials encapsulated in sample ampoules both in space and on Earth, we expect to explore some physical and chemical processes and mechanism of the materials formation that are normally obscured and therefore are difficult to study quantitatively on the ground due to the gravity-induced convection, to obtain the processing and synthesis technology for preparing high quality materials, and lead to the improvement and development of materials processing techniques on Earth, and also develop the experiment device and comprehensive ability for materials experiment in microgravity environment. This report briefly introduces the main points of each research work and preliminary comparative analysis results of 12 samples carried out by scientists undertaking research task. | LI Xiangyang LU Ye MENG Xiangjian WANG Jianlu WANG Reng CHEN Lidong HUA Zile LI Xiaoya SHI Jianlin LIU Jinfeng XU Guisheng WEI Bingbo XIE Wenjun YIN Zhigang ZHANG Xingwang JIANG Hongxiang LI Hong LUO Xinghong ZHANG Haifeng ZHAO Jiuzhou WANG Binbin PAN Mingxiang | 2018 | 空间科学学报2018，38，5： | 4 |
| 11 | A versatile photodetector assisted by photovoltaic and bolometric effects显示文摘The advent of low-dimensional materials with peculiar structure and superb band properties provides a new canonical form for the development of photodetectors.However,the limited exploitation of basic properties makes it difficult for devices to stand out.Here,we demonstrate a hybrid heterostructure with ultrathin vanadium dioxide film and molybdenum ditelluride nanoflake.Vanadium dioxide is a classical semiconductor with a narrow bandgap,a high temperature coefficient of resistance,and phase transformation.Molybdenum ditelluride,a typical two-dimensional material,is often used to construct optoelectronic devices.The heterostructure can realize three different functional modes:(i)the p-n junction exhibits ultrasensitive detection(450 nm-2μm)with a dark current down to 0.2 pA and a response time of 17μs,(ii)the Schottky junction works stably under extreme conditions such as a high temperature of 400 K,and(iii)the bolometer shows ultrabroad spectrum detection exceeding 10μm.The flexible switching between the three modes makes the heterostructure a potential candidate for next-generation photodetectors from visible to longwave infrared radiation(LWIR).This type of photodetector combines versatile detection modes,shedding light on the hybrid application of novel and traditional materials,and is a prototype of advanced optoelectronic devices. | Wei Jiang Tan Zheng Binmin Wu Hanxue Jiao Xudong Wang Yan Chen Xiaoyu Zhang Meng Peng Hailu Wang Tie Lin Hong Shen Jun Ge Weida Hu Xiaofeng Xu Xiangjian Meng Junhao Chu Jianlu Wang | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 12 | Effects of Ta Addition on NiTi Shape Memory Alloys显示文摘The effect of Ta addition on the martensitic transformation characteristics and the X-ray visibility on NiTi shape memory alloy have been studied in (Ni51Ti49)1-x Tax system. It was found that the transformation temperatures of the Ni51Ti49 binary alloy increased drastically by an addition of 0-4 at. pct Ta, but only slightly when the concentration exceeded 4 at. pct, the addition of Ta greatly decreases the sensitivity of the martensitic transformations to the variation in the Ni-Ti ratio. The addition of Ta to the NiTi binary alloy can improve its X-ray visibility. | Jianlu MA, Jiangnan LIU+, Zhengpin WANG and Fei XUE (Dept. of Materials Science & Engineering, Xi’an Institute of Technology, Xi’an 710032, China) Kuang-Hsi WU and Zhongjie PU (Department of Mechanical Engineering, Florida International University, USA) | 2000 | Journal of Materials Science & Technology2000，16，5： | 3 |
| 13 | Mechanisms of obesity-and diabetes mellitus-related pancreatic carcinogenesis:a comprehensive and systematic显示文摘Research on obesity-and diabetes mellitus(DM)-related carcinogenesis has expanded exponentially since these two diseases were recognized as important risk factors for cancers.The growing interest in this area is prominently actuated by the increasing obesity and DM prevalence,which is partially responsible for the slight but constant increase in pancreatic cancer(PC)occurrence.PC is a highly lethal malignancy characterized by its insidious symptoms,delayed diagnosis,and devastating prognosis.The intricate process of obesity and DM promoting pancreatic carcinogenesis involves their local impact on the pancreas and concurrent wholebody systemic changes that are suitable for cancer initiation.The main mechanisms involved in this process include the excessive accumulation of various nutrients and metabolites promoting carcinogenesis directly while also aggravating mutagenic and carcinogenic metabolic disorders by affecting multiple pathways.Detrimental alterations in gastrointestinal and sex hormone levels and microbiome dysfunction further compromise immunometabolic regulation and contribute to the establishment of an immunosuppressive tumor microenvironment(TME)for carcinogenesis,which can be exacerbated by several crucial pathophysiological processes and TME components,such as autophagy,endoplasmic reticulum stress,oxidative stress,epithelialmesenchymal transition,and exosome secretion.This review provides a comprehensive and critical analysis of the immunometabolic mechanisms of obesity-and DM-related pancreatic carcinogenesis and dissects how metabolic disorders impair anticancer immunity and influence pathophysiological processes to favor cancer initiation. | Rexiati Ruze Jianlu Song Xinpeng Yin Yuan Chen Ruiyuan Xu Chengcheng Wang Yupei Zhao | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 2 |
| 14 | Preparation of La0.67Ca0.23Sr0.1MnO3 thin films with interesting electrical and magnetic properties via pulsed-laser deposition显示文摘Manganese oxides with a perovskite-type Re_(1-x)D_xMnO_3(Re:heavy rare-earth elements,D:divalent alkali metal)structure have attracted interest because of the complex interaction between their electrons,lattices,and spins[1-5].Generally,manganese oxides with the structure Re_(1-x)D_xMnO_3 have special properties.For example,the half-metallic manganites,such as La_(2/3)Sr_(1/3)MnO_3 and La_(2/3)Ca_(1/3)MnO_3,wherein the conduction electrons are completely spin polarized。 | Shuai Xue XiaoLin Zhao JianLu Wang BoBo Tian Hai Huang CaiMin Meng Lan Liu Lei Ye JingLan Sun XiangJian Meng XiaoDong Zhang JunHao Chu | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，2： | 2 |
| 15 | Performance measurement of adaptive optics system based on Strehl ratio显示文摘In this article, a method for measuring the performance of adaptive optics(AO) systems is designed and validated by experiments. The Strehl ratio(SR) which is based on the target images is used to evaluate the performance quantitatively because it relates to the effect of AO correction directly. In the calculation of the SR, to avoid energy scaling in the diffraction-limited point spread function, an algorithm based on the integral of the optical transfer function(OTF) is proposed. Then, a 97-element AO system is established to validate this method, and a white-light fiber source is used as a point-like target. To simulate the practical conditions which influence the performance of the AO system, targets of different brightness are simulated in terms of different signal-to-noise ratios(SNRs) of the Shack-Hartmann(SH), and atmospheric turbulence is simulated in terms of the Fried's coherence length and the Greenwood's frequency. Finally, two experiments are conducted in which the SR of different simulated conditions are measured. The results of the experiments show that for a moderate SNR of SH the experimenting AO system is capable of closed-loop wavefront correction when the Fried's coherence length is larger than 5cm and the Greenwood's frequency is lower than 60 Hz. The results also show that the performance of AO is susceptible to the SNR of SH. The experiments validates the effectiveness of this method. | Wang Liang Chen Tao Lin Xudong Wei Peifeng Liu Xinyue Jia Jianlu | 2016 | The Journal of China Universities of Posts and Telecommunications2016，23，3： | 2 |
| 16 | Synthesis of Acetic Acid on Pd-H_4SiW_(12)O_(40)-Based Catalysts by Direct Oxidation of Ethylene显示文摘Synthesis of acetic acid by direct oxidation of ethylene on Pd-H4SiW12O4o-based catalystswas studied in a fixed-bed integral reactor and a pulse differential reactor. From the performance of thecatalysts with different compositions and configurations, it is proposed that acetic acid is predominantlyproduced via an intermediate of acetaldehyde. This can be easily confirmed by comparing the productdistributions in the integral and the differential reactors. The active sites for acetic acid formation areconsidered to exist mainly at the boundaries between the H4SiW12O4o and the Pd particles. The Pd-basedcatalysts reduced by H2/N2 have higher activities than those reduced by hydrazine, as explained by thedegree of Pd dispersion obtained from the characteristics of hydrogen chemical adsorption. It was foundthat the Pd-Se-SiW12/SiO2 catalyst with selenium tetrachloride as a precursor was more active than thatwith potassium selenite, and that the acetic acid yield can be greatly increased by adding a suitable amountof dichloroethane (C2H4Cl2/C2H4 mole ratio=0.03) to the reactants. | Xinping Wang Kegong Fang Jianlu Zhang Tianxi Cai | 2002 | Journal of Natural Gas Chemistry2002，11，1： | 2 |
| 17 | High temperature PEM fuel cells显示文摘 | Zhang Jianlu Xie Zhong Zhang Jiujun | 2006 | Journal of Power Sources2006，160，2： | 1 |
| 18 | Electrochemical energy storage for green grid显示文摘 | Yang Zhenguo Zhang Jianlu Kintner-Meyer Michael C W Lu Xiaochuan Choi Daiwon Lemmon John P Liu Jun | 2011 | Chemical Reviews2011，111，5： | 1 |
| 19 | Effect of kidney - type and circular cross section on carbon fiber surface and composite interface显示文摘 | XU Zhiwei LI Jianlu WU Xiaoqing | 2008 | Composites : Part A2008，39，2： | 1 |
| 20 | Novel carbon-supported Fe-N electrocatalysts synthesized through heat treatment of iron tripyridyl triazine complexes for the PEM fuel cell oxygen reduction reaction显示文摘 | Cicero W.B. Bezerra Lei Zhang Kunchan Lee Hansan Liu Jianlu Zhang Zheng Shi Aldaléa L.B. Marques Edmar P. Marques Shaohong Wu Jiujun Zhang | 2008 | Electrochimica Acta2008，，26： | 1 |
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