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| 1 | Honeysuckle-encoded atypical microRNA2911 directly Largets influenza A viruses显示文摘 | Zhen Zhou Xihan Li Jinxiong Liu Lei Dong Qun Chen Jialing Liu Huihui Kongt Qianyi Zhang Xian Qi Dongxia Hou Lin Zhang Guoquan Zhang Yuchen Liu Yujing Zhang Jing Li Jin Wang Xi Chen Hua Wang Junfeng Zhang Hualan Chen Ke Zen Chen-Yu Zhang | 2015 | Cell Research2015,25,1: | 104 |
| 2 | Rural E-commerce and New Model of Rural Development in China:A Comparative Study of 'Taobao Village' in Jiangsu Province显示文摘With the development of electronic commerce,there is a special phenomenon in rural areas of China that a lot of farmers in these areas depend on opening shops on Taobao online for a living. The products are made from the village workshop,and farmers become fullyfledged network businessmen. Electronic business platform mode of ' Taobao Village' is the result of integrated development of primary,secondary and tertiary industries. In this study,we take two kinds of typical Taobao villages( Dongfeng Village and Yanxia Village) as sample areas,and conduct comparative analysis of this new rural business model based on field survey data,case studies and theoretical research. We also probe into the problems in the development of Taobao villages,and set forth the recommendations for the new rural business model. | Changyu LIU Jiale LI Jing LIU | 2015 | Asian Agricultural Research2015,7,11: | 14 |
| 3 | Hic74,a novel alanine and glycine rich matrix protein related to nacreous layer formation in the mollusc Hyriopsis cumingii显示文摘Organic matrix proteins play an important role in the biomineralization of mollusc shells.We have identified and characterized a novel matrix protein,namely hic74,isolated from the mantle of the freshwater mussel Hyriopsis cumingii.The hic74 gene encodes a 850 amino acid protein that is rich in alanine(ala,30.8%),glycine(gly,25.8%)and serine(ser,10.6%),with ala mainly existing in poly-ala forms within the ala/gly-rich regions.Quantitative PCR expression analysis demonstrated that hic74 was specifically amplified from the mantle and in situ hybridization showed a strong signal in the epithelial cells in the pallial region of the mantle.Lower levels of expression were detected during the early stages of pearl sac formation but increased and remained constant during nacreous layer formation suggesting that hic74 might be involved in this process. | Xiaojun Liu Can Jin Leiming Wu Shaojian Dong Shimei Zeng Jiale Li | 2017 | Aquaculture and Fisheries2017,2,3: | 6 |
| 4 | The Research on 220GHz Multicarrier High-Speed Communication System显示文摘This paper presents our investigation into a 220 GHz multicarrier highspeed communication system based on solid state transceivers.The proposed system has eased the demand of high sampling rate analog-to-digital converter(ADC)by providing several signal carriers in microwave band and converting them to 220 GHz channel.The system consists of a set of 220 GHz solid-state transceiver with 2 signal carriers,two basebands for 4 GSPS ADCs.It has achieved 12.8 Gbps rate real-time signal transmission using 16QAM modulation over a distance of 20 m without any other auxiliary equipment or test instruments.The baseband algorithm overcomes the problem of frequency difference generates by non-coherent structure,which guarantees the feasibility of long-distance transmission application.Most importantly,the proposed system has already carried out multi-channel 8K video parallel transmission through switch equipment,which shows the multicarrier high-speed communication system in submillimeter wave has great application prospects.To the best of the authors’knowledge,this is the first all-solid-state electronics multicarrier communication system in submillimeter and terahertz band. | Zhongqian Niu Bo Zhang Jiale Wang Ke Liu Zhi Chen Ke Yang Zhen Zhou Yong Fan Yaohui Zhang Dongfeng Ji Yinian Feng Yang Liu | 2020 | China Communications2020,17,3: | 5 |
| 5 | ELASTIC-PLASTIC DYNAMIC RESPONSE OF FULLY BACKED SANDWICH PLATES UNDER LOCALIZED IMPULSIVE LOADING显示文摘An analytical model is developed to assess the elastic-plastic dynamic response of fully backed sandwich plates under localized impulse load.The core is modeled as an elastic-perfectly plastic foundation.The top face sheet is treated as an individual plate resting on the foundation.The elastic-plastic analysis for the top face sheet is based on a minimum principle in dynamic plasticity associated with the finite difference technique.The effects of spatial and temporal distributions of the impulsive loading on the dynamic response of sandwich plates are discussed.The model can be used to predict the impulse-induced local effect on fully backed sandwich plates. | Hua Liu Wuchao Chen Jialing Yang (The Solid Mechanics Research Center, Beijing University of Aeronautics and Astronautics, Beijing 100191, China) | 2010 | Acta Mechanica Solida Sinica2010,23,4: | 4 |
| 6 | Zephyranthes-like Co2NiSe4 arrays grown on 3D porous carbon frame-work as electrodes for advanced supercapacitors and sodium-ion batteries显示文摘Developing suitable electrode materials for electrochemical energy storage devices by biomorph assisted design has become a fascinating topic due to the fantastic properties derived from bio-architectures.Herein,zephyranthes-like Co_(2)NiSe_(4)arrays grown on butterfly wings derived three-dimensional(3D)carbon framework(Z-Co_(2)NiSe_(4)/BWC)is fabricated via hydrothermal assembly and further conversion method.Benefiting from its unique structure and multi-components,the obtained Z-Co_(2)NiSe_(4)/BWC electrode for supercapacitor delivers an excellent specific capacitance of 2,280 F·g^(-1)at 1 A·g^(-1).Impressively,the constructed asymmetric supercapacitor using Co_(2)NiSe_(4)/BWC as positive electrode and activated butterfly wings carbon as negative electrode acquires a high energy density of 42.9 Wh·kg^(-1)at a power density of 800 W·kg^(-1)with robust stability of 94.6%capacitance retention at 10 A·g^(-1)after 5,000 cycles.Moreover,the Z-Co_(2)NiSe_(4)/BWC as anode for sodium-ion batteries exhibits a high specific capacity of 568 mAh·g^(-1)at 0.1 A·g^(-1)and high cycling stability(maintaining 80.1%of the second cycle after 100 cycles).The outstanding electrochemical performances are ascribed to that the synergistic effect of bimetallic selenides and N-doped carbon improves electrochemical activities and conductivity.One-dimensional(1D)nanoneedles grown on 3D porous framework increase the exposure of redox-active sites,endow adequate transmission channels of electrons/ions,and guarantee stability of the electrode during charge/discharge processes.This study will shed light on the avenue towards extending such nanohybrids to excellent energy storage applications. | Yanchun Xue Xingmei Guo Mengrong Wu Jiale Chen Mengting Duan Jing Shi Junhao Zhang Fu Cao Yuanjun Liu Qinghong Kong | 2021 | Nano Research2021,14,10: | 3 |
| 7 | Effectiveness of tonifying-kidney and regulating-liver therapy on diminished ovarian reserve: a systematic review and Meta-analysis of randomized controlled trials显示文摘OBJECTIVE: To evaluate the effectiveness of the Traditional Chinese Medicine tonifying-kidney and regulating-liver therapy on diminished ovarian reserve(DOR).METHODS: The literature was comprehensively searched up to August 2019 using four Chinese and three English electronic databases to extract randomized clinical trials(RCTs) comparing Traditional Chinese Medicine tonifying-kidney and regulating-liver prescriptions(combined with hormone therapy or not) with Western Medicine. Data quality evaluation was conducted using the Cochrane risk of bias tool. Meta-analysis was conducted using Revman 5.3 software with effect estimates presented as mean difference(MD), risk ratio(RR), and95% confidence interval(CI).RESULTS: A total of nine RCTs with 512 participants were extracted and eligible for Meta-analysis.There were no significant differences between Chinese medicine and Western Medicine on basal serum follicle-stimulating hormone(FSH) level(MD0.11, 95% CI-0.52 to 0.74, 392 participants, seven trials), anti-Müllerian hormone level(MD 0.48, 95%CI-0.62 to 1.58, 95 participants, two trials), and the FSH and luteinizing hormone ratio(MD 0.01,95% CI-0.95 to 0.96, 115 participants, two trials).Chinese medicine was more effective at improving Traditional Chinese Medicine symptom scores(TCMSS)(MD-2.39, 95% CI-3.83 to-0.94, 160 participants, three trials), effective rate of TCMSS(RR1.18, 95% CI 1.02 to 1.36, 160 participants, three trials), antral follicle count(AFC)(MD 0.55, 95% CI 0.05 to 1.04, 155 participants, three trials), and FSH levels at 3 months post-treatment(MD-4.77, 95% CI-6.09 to-3.45, 137 participants, two trials).CONCLUSION: Compared with Western Medicine,tonifying-kidney and regulating-liver therapy is more effective at relieving symptoms and improving AFC and FSH at 3 months post-treatment. | Liu Liuqing Liu Yanfeng Yang Ming Xu Guiqin Li Ruiqi Xu Xiuli Pan Xue Liang Jialing | 2020 | Journal of Traditional Chinese Medicine2020,40,3: | 3 |
| 8 | In-situ construction of a Mg-modified interface to guide uniform lithium deposition for stable all-solid-state batteries显示文摘Uniform lithium(Li)deposition in all-solid-state Li metal batteries is greatly influenced by the anode/electrolyte interface.Herein,a Mg-modified interface was constructed via the simple in-situ electrochemical reduction of Mg^(2+)from Mg(TFSI)_(2) in polyethylene oxide(PEO)and a Li bis(trifluoromethane)sulfoni mide(Li TFSI)formulae.As confirmed by cryogenic transmission electron microscopy,the anode/electrolyte interface exhibited hybrids consisting of crystalline Mg,Li_(2)O,and Li dots embedded in an amorphous polymer electrolyte.The crystalline Mg dots guided the uniform Li nucleation and growth,inducing a smoother anode/electrolyte interface compared with the pristine electrolyte.With 1 wt%Mg(TFSI)_(2) in the PEO-Li TFSI electrolyte,the Mg-modified electrolyte enabled the Li/Li symmetric cells with cycling performance of over 1700 and 1400 h at current densities of 0.1 and 0.2 m A cm^(-2),respectively.Moreover,the full LFP/Li cells using the novel Mg-modified electrolyte delivered a cycling lifespan of over 450 cycles with negligible capacity loss. | Tiefeng Liu Jiale Zheng Hualiang Hu Ouwei Sheng Zhijin Ju Gongxun Lu Yujing Liu Jianwei Nai Yao Wang Wenkui Zhang Xinyong Tao | 2021 | Journal of Energy Chemistry2021,30,4: | 3 |
| 9 | A Robust Zero-Watermarking Based on SIFT-DCT for Medical Images in the Encrypted Domain显示文摘Remote medical diagnosis can be realized by using the Internet,but when transmitting medical images of patients through the Internet,personal information of patients may be leaked.Aim at the security of medical information system and the protection of medical images,a novel robust zero-watermarking based on SIFT-DCT(Scale Invariant Feature Transform-Discrete Cosine Transform)for medical images in the encrypted domain is proposed.Firstly,the original medical image is encrypted in transform domain based on Logistic chaotic sequence to enhance the concealment of original medical images.Then,the SIFT-DCT is used to extract the feature sequences of encrypted medical images.Next,zero-watermarking technology is used to ensure that the region of interest of medical images are not changed.Finally,the robust of the algorithm is evaluated by the correlation coefficient between the original watermark and the attacked watermark.A series of attack experiments are carried out on this method,and the results show that the algorithm is not only secure,but also robust to both traditional and geometric attacks,especially in clipping attacks. | Jialing Liu Jingbing Li Yenwei Chen Xiangxi Zou Jieren Cheng Yanlin Liu Uzair Aslam Bhatti | 2019 | Computers, Materials & Continua2019,,7: | 3 |
| 10 | Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation显示文摘Dear Editor,Herpesviridae is a large family of double-stranded DNA(dsDNA)viruses that cause a variety of human diseases ranging from cold sores and chicken pox to congenital defects,blindness and cancer(Chayavichitsilp et al.,2009;Wang et al.,2018).In the past 70 years,substantial advances in our knowledge of the molecular biology of herpesviruses have led to insights into disease pathogenesis and management.However,the mechanism for capsid assembly that requires the ordered packing of about 4,000 protein subunits into the hexons,pentons and triplexes remains elusive.It is still a puzzle how initially identical subunits adopt both hexameric and pentameric conformations in the capsid and select the correct locations needed to form closed shells of the proper size.Biochemical and genetic studies have shown that the portal is involved in initiation of capsid assembly(Newcomb et al.,2005)and functions akin to a DNA-sensor coupling genome-packaging achieved by a genome-packaging machinery-“terminase complex”(Chen et al.,2020;Yunxiang Yang,2020)with icosahedral capsid maturation(Lokareddy et al.,2017).Structural investigations of the herpesvirus portal have proven challenging due to the small size of this dodecamer,which accounts for less than 1%of the total mass of the capsid protein layer and the technical difficulties involved in resolving non-icosahedral components of such large icosahedral viruses(diameter is∼1,250Å).Efforts of many investigators over two decades have made to reconstruct the cryo-electron microscopy(cryo-EM)structure of herpesvirus portal vertex and more recently near-atomic structures of two herpesvirus(herpes simplex virus type 1(HSV-1)and Kaposi’s sarcoma-associated herpesvirus(KSHV))portal vertices were reported(McElwee et al.,2018;Gong et al.,2019;Liu et al.,2019). | Nan Wang Wenyuan Chen Ling Zhu Dongjie Zhu Rui Feng Jialing Wang Bin Zhu Xinzheng Zhang Xiaoqing Chen Xianjie Liu Runbin Yan Dongyao Ni Grace Guoying Zhou Hongrong Liu Zihe Rao Xiangxi Wang | 2020 | Protein & Cell2020,11,5: | 2 |
| 11 | Effect of a viscoelastic target on the impact response of a flat-nosed projectile显示文摘Taylor impact is a widely used strategy in which a flat-nosed projectile is fired onto a rigid anvil directly to determine the dynamic strength of rod specimens. Nowadays, the rigid anvil is often replaced by an output target bar to ensure the accuracy of measurement via recording strain signals in the output bar. For testing the dynamic strength of low-density materials, a low-impedance target bar, which exhibits viscoelastic characteristics is often employed. In this paper, an extended Taylor model is proposed to improve the idealization of treating the target bar as perfectly rigid material in the classic Taylor model, and the viscoelastic effect of the target bar is incorporated. The viscoelastic target bar is depicted by two elastic springs and one dashpot. Based on the plastic shock wave theory in the flat-nosed projectile associated with the viscoelastic wave analysis in the target bar, the viscoelastic effect of the target bar on the impact response of the flat-nosed projectile is investigated. The finite element simulation is also carried out to verify the theoretical model,and good agreement is found. The present theoretical model is also called the Taylor-cylinder Hopkinson impact, which provides a more accurate way to identify the dynamic material parameters. The dynamic responses of the present model are further compared with previous elastic and rigid target bar models. It is found that the viscoelastic effect of the target bar should be taken into consideration in the Taylor-cylinder Hopkinson impact test for low-impedance materials. | Hu Liu Jialing Yang Hua Liu | 2018 | Acta Mechanica Sinica2018,34,1: | 2 |
| 12 | Photocrosslinking silver nanoparticles–aloe vera–silk fibroin composite hydrogel for treatment of full-thickness cutaneous wounds显示文摘Damage to the skin causes physiological and functional issues.The most effective treatment approach is the use of wound dressings.Silk fibroin(SF)is a promising candidate biomaterial for regulating wound healing;however,its antibacterial properties and biological activity must be further improved.In this study,a photocrosslinking hydrogel was developed to treat full-thickness cutaneous wounds.The composite hydrogel(Ag-AV-SF hydrogel)was prepared by introducing the silver nanoparticles(AgNPs)and aloe vera(AV)as the modifiers.In vitro study exhibited great antibacterial ability,biocompatibility and cell-proliferation and-migration-promoting capacities.It also showed the pH-response releasing properties which release more AgNPs in a simulated chronic infection environment.The healing effect evaluation in vivo showed the healing-promoting ability of the Ag-AV-SF hydrogel was stronger than the single-modifiers groups,and the healing rate of it reached 97.02%on Day 21,higher than the commercial wound dressing,silver sulfadiazine(SS)cream on sale.Additionally,the histological and protein expression results showed that the Ag-AV-SF hydrogel has a greater effect on the pro-healing regenerative phenotype with M2 macrophages at the early stage,reconstructing the blood vessels networks and inhibiting the formation of scars.In summary,the Ag-AV-SF hydrogel developed in this study had good physical properties,overwhelming antibacterial properties,satisfactory biocompatibility and significantly promoting effect on cell proliferation,migration and wound healing.Overall,our results suggest that the Ag-AV-SF hydrogel we developed has great potential for improving the wound healing in clinical treatment. | Yangkun Liu JinChuan Fan MingQi Lv Kepeng She Jiale Sun Qingqing Lu Changhao Han SongTao Ding Shuang Zhao GuiXue Wang YuChan Zhang GuangChao Zang | 2021 | Regenerative Biomaterials2021,8,6: | 2 |
| 13 | Large deflection of curved elastic beams made of Ludwick type material显示文摘The large deflection of an axially extensible curved beam with a rectangular cross-section is investigated. The elastic beam is assumed to satisfy the Euler-Bernoulli postulation and be made of the Ludwick type material. Through reasonably simplified integration, the strain and curvature of the axis of the beam are presented in implicit formulations. The governing equations involving both geometric and material nonlinearities of the curved beam are derived and solved by the shooting method. When the initial curvature of the beam is zero, the curved beam is degenerated into a straight beam,and the predicted results obtained by the present model are consistent with those in the open literature. Numerical examples are further given for curved cantilever and simply supported beams, and the couplings between elongation and bending are found for the curved beams. | Hua LIU Yi HAN Jialing YANG | 2017 | Applied Mathematics and Mechanics(English Edition)2017,38,7: | 2 |
| 14 | Direct analysis in real time mass spectrometry combined with single-drop liquid–liquid–liquid microextraction for the rapid analysis of multiple phytohormones in fruit juice显示文摘 | Yu Bai Jialing Zhang Yu Bai Huwei Liu | 2012 | Analytical and Bioanalytical Chemistry2012,,: | 1 |
| 15 | Effective nanotherapeutic approach for metastatic breast cancer treatment by supplemental oxygenation and imaging-guided phototherapy显示文摘Metastasis remains the primary cause for mortality of breast cancer.Despite advances in current therapeutic agents,patients with metastatic breast cancer still have poor prognoses.Tumor hypoxia,a key microenvironment factor,is emerging as an attractive target to prevent metastasis and is also involved with resistance to phototherapy.Here,we show an effective nanotherapeutic approach based on manganese dioxide-coated polydopamine nanocarriers to trigger robust anti-tumor and anti-metastasis responses against metastatic breast cancer by supplemental oxygenation and multimodal imaging-guided phototherapies.In cancer cells,the produced oxygen by the developed nanoplatform decreases the expression of hypoxia-inducible factors 1 a to inhibit tumor metastasis,and enhances the efficacy of photodynamic therapy.This nanotherapeutic approach enables the combined photodynamic/photothermal treatments with great inhibition on cell migration and invasion in vitro.Moreover,the nanotherapeutics effectively suppresses primary tumor progress and inhibits lung metastasis in v ivo in a breast cancer mouse model with satisfying biosafety.This study suggests that the tumor hypoxia-targeting nanotherapeutics have great potential for preventing and treating metastatic cancers. | Jialing Hu Fuan Wang Feng Liu Wentong Sun Qunying Jiang Yahua Liu Yun Zhao Xiaoqing Liu | 2020 | Nano Research2020,13,4: | 1 |
| 16 | Atmospheric Particle Hygroscopicity and the Influence by Oxidation State of Organic Aerosols in Urban Beijing显示文摘A hygroscopic tandem differentialmobility analyser(H-TDMA)was used to observe the sizeresolved hygroscopic characteristics of submicron particles in January and April 2018 in urban Beijing.The probability distribution of the hygroscopic growth factor(HGF-PDF)in winter and spring usually showed a bimodal pattern,with more hygroscopic mode(MH)being more dominant.The seasonal variation in particle hygroscopicity was related to the origin of air mass,which received polluted southerly air masses in spring and clean northwesterly air masses in winter.Particles showed stronger hygroscopic behaviour during heavy pollution episodes(HPEs)with elevated concentrations of secondary aerosols,especially higher mass fraction of nitrate,which were indicated using the PM2.5(particulate matter with diameter below 2.5μm)mass concentration normalised by CO mass concentration.The hygroscopic parameter(κ)values were calculated using H-TDMA(κhtdma)and chemical composition(κchem).The closure study showed thatκchem was overestimated in winter afternoon when compared withκhtdma,because the organic particle hygroscopic parameter(κorg)was overestimated in the calculations.It was influenced by the presence of a high concentration of hydrocarbon-like organic aerosol(HOA)with a weak water uptake ability.A positive relationship was observed betweenκorg and the ratio of oxygenated organic aerosol(OOA)and HOA,thereby indicating that the strong oxidation state enhanced the hygroscopicity of the particles.This study revealed the effect of local emission sources and secondary aerosol formation processes on particle hygroscopicity,which is of great significance for understanding the pollution formation mechanism in the North China Plain. | Sinan Zhang Xiaojing Shen Junying Sun Yangmei Zhang Xiaoye Zhang Can Xia Xinyao Hu Junting Zhong Jialing Wang Shuo Liu | 2023 | Journal of Environmental Sciences2023,,2: | 1 |
| 17 | Development of solvent micro-extraction combined with derivatization显示文摘 | Huaqing Lin Jiale Wang Lingjie Zeng Gang Li Yunfei Sha Da Wu Baizhan Liu | 2013 | Journal of Chromatography A2013,,: | 1 |
| 18 | Vascular remodeling after ischemic stroke: Mechanisms and therapeutic potentials显示文摘 | Jialing Liu Yongting Wang Yosuke Akamatsu Chih Cheng Lee R. Anne Stetler Michael T. Lawton Guo-Yuan Yang | 2013 | Progress in Neurobiology2013,,: | 1 |
| 19 | Clopidogrel,aplateletP2Y12receptor inhibitor, reduces vascular inflammation andangiotensin Ⅱ inducedabdominal aortic aneurysmprogression显示文摘 | Liu O JiaL LiuX etal | 2012 | PloSOne2012,7,51: | 1 |
| 20 | JNK Suppresses Apoptosis via Phosphorylation of the Proapoptotic Bcl-2 Family Protein BAD显示文摘 | Chenfei Yu Yuzuru Minemoto Jiyan Zhang Jing Liu Fangming Tang Truc N. Bui Jialing Xiang Anning Lin | 2004 | Molecular Cell2004,,3: | 1 |