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| 1 | Characterization of QTL for unique agronomic traits of new-plant-type rice varieties using introgression lines of IR64显示文摘To enhance the yield potential of an elite indica rice cultivar,an introgression(BC_3-derived) line of IR64,YTH288,was developed using a new-plant-type cultivar,IR66215-44-2-3,as a donor parent.YTH288 has agronomically valuable characteristics such as large panicles,few unproductive tillers,and large leaves inherited from NPT.To identify the genetic basis of these traits,we used 167 F_2 plants derived from a cross between IR64 and YTH288 to conduct QTL analysis for five agronomic traits:days to heading(DTH),culm length(CL),flag leaf length(FLL),flag leaf width(FLW),and filled spikelet number per panicle(FSN).Six putative QTL were detected:four on chromosome4(for CL,FLL,FLW,and FSN) and two on chromosome 2(for DTH and FLL).All QTL with the IR66215-44-2-3 allele,except that for FLL on chromosome 2,had positive effects on each trait.To confirm the effects of these putative QTL,we developed NILs with the IR64 genetic background by marker-assisted selection.We observed significant differences in several agronomic traits between IR64 and NILs that carried these QTL on chromosomes2 and 4.Additionally,four IR64-NILs carrying chromosomal segments derived from different NPT varieties on the long arm of chromosome 4 exhibited similar pleiotropic To enhance the yield potential of an elite indica rice cultivar, an introgression(BC3-derived) line of IR64, YTH288, was developed using a new-plant-type cultivar,IR66215-44-2-3, as a donor parent. YTH288 has agronomically valuable characteristics such as large panicles, few unproductive tillers, and large leaves inherited from NPT.To identify the genetic basis of these traits, we used 167 F2 plants derived from a cross between IR64 and YTH288 to conduct QTL analysis for five agronomic traits: days to heading(DTH), culm length(CL), flag leaf length(FLL), flag leaf width(FLW), and filled spikelet number per panicle(FSN). Six putative QTL were detected: four on chromosome4(for CL, FLL, FLW, and FSN) and two on chromosome 2(for DTH and FLL). All QTL with the IR66215-44-2-3 allele, except that for FLL on chromosome 2, had positive effects on each trait. To confirm the effects of these putative QTL, we developed NILs with the IR64 genetic background by marker-assisted selection. We observed significant differences in several agronomic traits between IR64 and NILs that carried these QTL on chromosomes2 and 4. Additionally, four IR64-NILs carrying chromosomal segments derived from different NPT varieties on the long arm of chromosome 4 exhibited similar pleiotropiceffects for unique agronomic traits. These NILs can be used as research materials for studying each trait and as breeding materials for yield improvement of indica rice cultivars. | Analiza G.Tagle Daisuke Fujita Leodegario A.Ebron Mary Jeanie Telebanco-Yanoria Kazuhiro Sasaki Tsutomu Ishimaru Yoshimichi Fukuta Nobuya Kobayashi | 2016 | The Crop Journal2016，4，1： | 2 |
| 2 | Identification of Molecular Subtypes of Gastric Cancer with Different Responses to PI3-Kinase Inhibitors and 5-Fluorouracil显示文摘 | Zhengdeng Lei Iain Beehuat Tan Kakoli Das Niantao Deng Hermioni Zouridis Sharon Pattison Clarinda Chua Zhu Feng Yeoh Khay Guan Chia Huey Ooi Tatiana Ivanova Shenli Zhang Minghui Lee Jeanie Wu Anna Ngo Sravanthy Manesh Elisabeth Tan Bin Tean Teh Jimmy Bok | 2013 | Gastroenterology2013，，： | 2 |
| 3 | Hydrogels for tissue engineering: scaffold design variables and applications显示文摘 | Jeanie L. Drury David J. Mooney | 2003 | Biomaterials2003，，24： | 2 |
| 4 | Hydrogels for tissue engineering: Scaffold design variables and applications显示文摘 | Jeanie L Drury David J Mooney | 2003 | Biomaterials2003，24，： | 1 |
| 5 | Hydrogels for tissue engineering: scaffold design variables and applications显示文摘 | Jeanie L Drury David J Mooney | 2003 | Biomaterials2003，24，： | 1 |
| 6 | Response of the neonatal rat cardiomyocyte in culture to energy depletion:effects of cytokines,nitric oxide,and heat shock proteins显示文摘 | Dachun W Jeanie B Millin M | 1996 | Lab invest1996，75，6： | 1 |
| 7 | Hey! What About Us?! Changing Roles of Subject Specialists and Reference Librarians in the Age of E- lectronic Resource显示文摘 | Welch Jeanie M | 2002 | Serials Review2002，28，4： | 1 |
| 8 | From Formalism to Feminism显示文摘 | Case Sue Ellen and Forte Jeanie K | 1985 | Theater1985，16，1985： | 1 |
| 9 | Electrocardiogram abnormalities among men with stress-related psychiatric disorders: Implications for coronary heart disease and clinical research显示文摘 | Joseph A. Boscarino Ph.D. M.P.H. Jeani Chang M.P.H | 1999 | Annals of Behavioral Medicine1999，，3： | 1 |
| 10 | Expression of two tissue-specific promoters in transgenic cotton plants显示文摘 | Ping Song Jeanie L Heinen Teresa H Burns | 2000 | The Journal of Cotton Science2000，4，： | 1 |
| 11 | Electrocardiogram abnormalities among men with stress-related psychiatric disorders: Implications for coronary heart disease and clinical research显示文摘 | Joseph A. Boscarino Ph.D. M.P.H. Jeani Chang M.P.H | 1999 | Annals of Behavioral Medicine1999，，3： | 1 |
| 12 | Increased resistance to oxidative stress in transgenic plants that overexpress chloroplastic Cu/Zn superoxidc dismutasc显示文摘 | Ashima Sen Gupta Jeanie L heinenjohn J | 1993 | Proc Natc Acad USA1993，90，： | 1 |
| 13 | Silent Partners:Public Libraries and Their Services to Small Businesses and Entrepreneurs显示文摘 | Jeanie M.Welch | | 0，，05： | 1 |
| 14 | Intrinsic Subtypes of Gastric Cancer, Based on Gene Expression Pattern, Predict Survival and Respond Differently to Chemotherapy显示文摘 | Iain Beehuat Tan Tatiana Ivanova Kiat Hon Lim Chee Wee Ong Niantao Deng Julian Lee Sze Huey Tan Jeanie Wu Ming Hui Lee Chia Huey Ooi Sun Young Rha Wai Keong Wong Alex Boussioutas Khay Guan Yeoh Jimmy So Wei Peng Yong Akira Tsuburaya Heike Grabsch Han Chon | 2011 | Gastroenterology2011，，2： | 1 |
| 15 | Metabolomics in chronic hepatitis C:Decoding fibrosis grading and underlying pathways显示文摘BACKGROUND Chronic Hepatitis C(CHC)affects 71 million people globally and leads to liver issues such as fibrosis,cirrhosis,cancer,and death.A better understanding and prognosis of liver involvement are vital to reduce morbidity and mortality.The accurate identification of the fibrosis stage is crucial for making treatment decisions and predicting outcomes.Tests used to grade fibrosis include histological analysis and imaging but have limitations.Blood markers such as molecular biomarkers can offer valuable insights into fibrosis.AIM To identify potential biomarkers that might stratify these lesions and add information about the molecular mechanisms involved in the disease.METHODS Plasma samples were collected from 46 patients with hepatitis C and classified into fibrosis grades F1(n=13),F2(n=12),F3(n=6),and F4(n=15).To ensure that the identified biomarkers were exclusive to liver lesions(CHC fibrosis),healthy volunteer participants(n=50)were also included.An untargeted metabolomic technique was used to analyze the plasma metabolites using mass spectrometry and database verification.Statistical analyses were performed to identify differential biomarkers among groups.RESULTS Six differential metabolites were identified in each grade of fibrosis.This six-metabolite profile was able to establish a clustering tendency in patients with the same grade of fibrosis;thus,they showed greater efficiency in discriminating grades.CONCLUSION This study suggests that some of the observed biomarkers,once validated,have the potential to be applied as prognostic biomarkers.Furthermore,it suggests that liquid biopsy analyses of plasma metabolites are a good source of molecular biomarkers capable of stratifying patients with CHC according to fibrosis grade. | Adriana Camargo Ferrasi Samara Vitória Granja Lima Aline Faria Galvani Jeany Delafiori Flavia Luísa Dias-Audibert Rodrigo Ramos Catharino Giovanni Faria Silva Roberta Rodrigues Praxedes Driele Bretones Santos Dayane Trevisan de Macedo Almeida Estela Oliveira Lima | 2023 | World Journal of Hepatology2023，15，11： | 1 |
| 16 | Interprofessional teamworking: what makes teams work well?显示文摘 | Jeanie Molyneux | 2001 | Journal of Interprofessional Care2001，，： | 1 |
| 17 | A randomized controlled trial of a specific reminiscence approach to promote the well-being of nursing home residents with dementia显示文摘 | Claudia KY Lai IC Jeanie K | 2004 | Int Psychog2004，16，1： | 1 |
| 18 | Echocardiographie and palhoanatomical characteristics of isolated left ventricular non-compaction: a step towards classification as a distinct cardiomyopathy显示文摘 | Jeani R Oechslina E Schneiderb J | 2001 | Heart2001，86，： | 1 |
| 19 | Intrinsic Subtypes of Gastric Cancer, Based on Gene Expression Pattern, Predict Survival and Respond Differently to Chemotherapy显示文摘 | Iain Beehuat Tan Tatiana Ivanova Kiat Hon Lim Chee Wee Ong Niantao Deng Julian Lee Sze Huey Tan Jeanie Wu Ming Hui Lee Chia Huey Ooi Sun Young Rha Wai Keong Wong Alex Boussioutas Khay Guan Yeoh Jimmy So Wei Peng Yong Akira Tsuburaya Heike Grabsch Han Chon | 2011 | Gastroenterology2011，，2： | 1 |
| 20 | Toxicity of Triamcinolon Acetonide on Retinal Neurosensory and Pigment Epithelial Cells显示文摘 | Raja N Jeanie KM Cristina K | 2006 | Investigative Ophthalmology and Visual Science2006，47，2： | 1 |
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