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| 1 | Surgical strategies for giant medial sphenoid wing meningiomas: a new scoring system for predicting extent of resection显示文摘BACKGROUND: Surgical management of giant medial sphenoid meningiomas (> or =5 cm in maximum dimension) is ex-tremely challenging due to their intimate relationship with vital neural structures like the optic nerve, cranial nerves of | Behari S Giri PJ Shukla D Jain VK Banerji D | 2008 | 中国神经肿瘤杂志2008，6，3： | 7 |
| 2 | Esophageal tuberculosis presenting with hematemesis显示文摘Esophageal tuberculosis is rare, constituting about 0.3% of gastrointestinal tuberculosis. It presents commonly with dysphagia, cough, chest pain in addition to fever and weight loss. Complications may include hemorrhage from the lesion, development of arterioesophageal fistula, esophagocutaneous fistula or tracheoesophageal fistula. There are very few reports of esophageal tuberculosis presenting with hematemesis due to ulceration. We report a patient with hematemesis that was due to the erosion of tuberculous subcarinal lymph nodes into the esophagus. A 15-year-old boy presented with hemetemesis as his only complaint. Esophagogastroduodenoscopy(EGD) revealed an eccentric ulcerative lesion involving 50% of circumference of the esophagus. Biopsy showed caseating epitheloid granulomas with lymphocytic infiltrates suggestive of tuberculosis. Computerised tomography of the thorax revealed thickening of the mid-esophagus with enlarged mediastinal lymph nodes in the subcarinal region compressing the esophagus along with moderate right sided pleural effusion. Patient was treated with anti-tuberculosis therapy(Rifampicin, Isoniazid, Pyrazinamide, Ethambutol) for 6 mo. Repeat EGD showed scarring and mucosal tags with complete resolution of the esophageal ulcer. | Samit S Jain Piyush O Somani Rajeshkumar C Mahey Dharmesh K Shah Qais Q Contractor Pravin M Rathi | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，11： | 6 |
| 3 | Coagonist of glucagon-like peptide-1 and glucagon receptors ameliorates kidney injury in murine models of obesity and diabetes mellitus显示文摘AIM To investigate the role of glucagon-like peptide-1(GLP-1)/glucagon receptors coagonist on renal dysfunction associated with diabetes and obesity. METHODS Chronic high-fat diet fed C57 BL/6 J mice, streptozotocintreated high-fat diet fed C57 BL/6 J mice and diabeticC57 BLKS/J db/db mice were used as models of diabetes-induced renal dysfunction. The streptozotocintreated high-fat diet fed mice and db/db mice were treated with the GLP-1 and glucagon receptors coagonist(Aib2 C24 Chimera2, 150 μg/kg, sc) for twelve weeks, while in chronic high-fat diet fed mice, coagonist(Aib2 C24 Chimera2, 150 μg/kg, sc) treatment was continued for forty weeks. Kidney function, histology, fibrosis, inflammation, and plasma biochemistry were assessed at the end of the treatment. RESULTS Coagonist treatment decreased body weight, plasma lipids, insulin resistance, creatinine, blood urea nitrogen, urinary albumin excretion rate and renal lipids. In kidney, expression of lipogenic genes(SREBP-1 C, FAS, and SCD-1) was decreased, and expression of genes involved in β-oxidation(CPT-1 and PPAR-α) was increased due to coagonist treatment. In plasma, coagonist treatment increased adiponectin and FGF21 and decreased IL-6 and TNF-?. Coagonist treatment reduced expression of inflammatory(TNF-α, MCP-1, and MMP-9) and pro-fibrotic(TGF-β, COL1 A1, and α-SMA) genes and also improved histological derangement in renal tissue.CONCLUSION Coagonist of GLP-1 and glucagon receptors alleviated diabetes and obesity-induced renal dysfunction by reducing glucose intolerance, obesity, and hyperlipidemia. | Vishal J Patel Amit A Joharapurkar Samadhan G Kshirsagar Brijesh K Sutariya Maulik S Patel Hiren M Patel Dheerendra K Pandey Rajesh H Bahekar Mukul R Jain | 2018 | World Journal of Diabetes2018，9，6： | 5 |
| 4 | Response of blood pressure after percutaneous transluminal renal artery angioplasty and stenting显示文摘AIM: To evaluate the short and intermediate term out-come of percutaneous transluminal renal artery angioplasty (PTRA) and stenting particularly on blood pressure (BP) control and renal function and to evaluate predictors of poor BP response after successful PTRA and stenting. METHODS: We conducted a prospective analysis of all patients who underwent PTRA and stenting in our institute between August 2010 to September 2012. A total number of 86 patients were underwent PTRA and renal stenting. Selective angiography was done to confirm at least 70% angiographic stenosis. The predilatation done except few cases with critical stenosis, direct stenting was done in the rest of cases. All patients received aspirin 325 mg orally, and clopidogrel 300 mg orally within 24 h before the procedure. Heparin was used as the procedural anticoagulant agent. Optimal results with TIMI-Ⅲ flow obtained in all cases. Following stent placement, aspirin 150 mg orally once daily was continued for a minimum of 12 mo and clopidogrel 75 mg orally once daily for at least 4 wk. The clinical, radiological, electrocardiography, echocardiography and treatment data of all patients were recorded. The BP measurement, serum creatinine and glomerular filtration rate (GFR) were recorded before the procedure and 1 and 6 mo after PTRA. RESULTS: A total of 86 patients were included in the study. The mean age of study population was 55.87±11.85 years old and 67 (77.9%) of patients were male. There was a significant reduction in both systolic and diastolic BP at 1 mo after the procedure: 170.15±20.10 mmHg vs 146.60±17.32 mmHg and 98.38±10.55 mmHg vs 89.88±9.22 mmHg respectively (P=0.0000). The reduction in BP was constant throughout the follow-up period and was evident 6 mo after the procedure: 144.23±18.19 and 88.26±9.79 mmHg respectively (P=0.0000). However, no improvement in renal function was observed at any time during the follow-up period. After multivariate analysis, we found male sex, low GFR (<60 mL/min) and higher baseline mean BP as a poor predictors of successful outcome on BP response after PTRA and stenting. CONCLUSION: The PTRA and stenting can be considered as an effective therapeutic intervention for improving BP control with minimal effect on renal function. The male sex, higher baseline BP and low GFR are associated with poor BP response after successful PTRA and stenting. | Jayesh S Prajapati Sharad R Jain Hasit Joshi Shaurin Shah Kamal Sharma Sibasis Sahoo Kapil Virparia Ashok Thakkar | 2013 | World Journal of Cardiology2013，5，7： | 3 |
| 5 | Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior显示文摘服的外皮为集成是必要的并且为大多数行为被要求的信息处理。当神经原从室的地区连续地移居联合进特定的外皮的层时,服的外皮的精致地精确的 laminar 组织在胚胎的开发期间产生。当时指南为设计神经原移植责骂的光线的神经胶质行为, pre-formed 脉管的网络为 GABAergic interneuron 移植提供支持和指导暗示。这研究提供新奇概念、机械学的卓见进 vascular-neuronal 相互作用的这个范例,揭示伽马氨基丁酸并且它经由胚胎的前脑 endothelial 房间的调停受体的发信号的新机制。与二个新 endothelial 房间的使用,特定的有条件的老鼠 GABA 小径当模特儿(Gabrb3 Tie2-Cre 和 Vgat 我们显示出的 Tie2-Cre ), 从 endothelial 房间的伽马氨基丁酸版本的那部分或完全的损失在 embryogenesis 期间导致脉管的缺点并且损害长途的移植并且外皮的 interneurons 放。使不安的 endothelial 的下游的效果导出房间的伽马氨基丁酸发信号是批评的,导致上次修改到外皮的电路和坚持的行为的赤字。而且,我们说明在支持他们血大脑障碍性质的迁居, angiogenesis 和获得的前脑 endothelial 房间发信号的伽马氨基丁酸的激活的新机制。我们的调查结果揭开并且阐明在从表明小径的古典 neuronal 伽马氨基丁酸是不同的并且在 neuropsychiatric 疾病的病原学和 pathophysiology 上打开新灯的 CNS 表明小径的新奇 endothelial 伽马氨基丁酸例如孤独性光谱混乱,癫痫,焦虑,消沉和精神分裂症。 | Suyan Li Peeyush Kumar Sampada Joshee Timo Kirschstein Sivan Subburaju Jahan S Khalili Jonas Kloepper Chuang Du Abdallah Elkhal Gabor Szabo Rakesh K Jain Rudiger Kohling Anju Vasudevan | 2018 | Cell Research2018，28，2： | 3 |
| 6 | A new technique for the analysis of self-excited induction generator显示文摘 | SINGH S P JAIN M P | 1995 | Electric Machine and Power Systems1995，23，： | 2 |
| 7 | Molecular characterization of the murine Hif-1α locus显示文摘 | Luo G Gu Y Z Jain S | 1997 | Gene Exp1997，6，5： | 2 |
| 8 | Diffraction of elastic P waves by two equal co-axial circular rigid strips显示文摘 | Verma S K Jain D L | 1992 | European Journal of Mechanics A/Solids1992，11，2： | 2 |
| 9 | First rib fractures: not always a hallmark of severe trauma a report of three cases显示文摘 | Atin Jaiswal Yashwant S Tanwar Masood Habib Vijay Jain | 2013 | Chinese Journal of Traumatology2013，16，4： | 2 |
| 10 | Adverse events of upper GI endoscopy显示文摘 | Tamir Ben-Menachem G. Anton Decker Dayna S. Early Jerry Evans Robert D. Fanelli Deborah A. Fisher Laurel Fisher Norio Fukami Joo Ha Hwang Steven O. Ikenberry Rajeev Jain Terry L. Jue Khalid M. Khan Mary L. Krinsky Phyllis M. Malpas John T. Maple Ravi N. S | 2012 | Gastrointestinal Endoscopy2012，，4： | 2 |
| 11 | The crucial role of cyclooxygenase-2 in osteopontin-induced protein kinase C alpha/c-Src/ IkappaB kinase alpha/beta-dependent prostate tumor progression and angiogenesis显示文摘 | Jain S Chakraborty G Kundu GC | 2006 | Cancer Res2006，66，13： | 1 |
| 12 | Protective role of zeolite on short-and long-term lead toxicity in the teleost fish Heteropncustes fossilis显示文摘 | Jain S K | 1999 | Chemosphere1999，39，2： | 1 |
| 13 | Polycyclic aromatic hydrocarbons: environmental pollution and bioremediation 显示文摘 | SAMANTA S K SINGH O V JAIN R K | 2002 | Trends Biotechnol2002，20，6： | 1 |
| 14 | On pre-straining and the evolution of material anisotropy in sheet metals显示文摘 | WU P D MACEWEN S R LLOYD D J JAIN M TUGCU P NEALE K W | 2005 | Int J Plasticity2005，21，： | 1 |
| 15 | Hospitalized patients with 2009 H1N1 influenza in the United States, April- June 2009 显示文摘 | Jain S Kamimoto L Bramley AM | 2009 | N Engl J Med2009，361，20： | 1 |
| 16 | Neurturin-mediated ret activation is required for retinal function 显示文摘 | Brantley MA Jr Jain S Barr EE | 2008 | J Nenrosci2008，28，16： | 1 |
| 17 | Time and pH Dependent Colon Specific, Pulsatile Delivery of Theophylline for Nocturnal Asthma显示文摘 | Mastiholimath V S Dandagi P M Samata Jain S Gadad A P Kulkarni A R | 2007 | International Journal of Pharmaceutics2007，328，： | 1 |
| 18 | Timing, quantification and tectonic modelling of Pliocene-Quartenary movements in the NW Himalaya:evidence from fission track dating显示文摘 | Kumar D Singh S | 2000 | Earth and Planetary Science Letters2000，179，43： | 1 |
| 19 | Neurotieism and stressful life events in patients with non - ulcer dyspepsia 显示文摘 | Jain AK Gupta JP Gupta S | 1995 | J Assoc Physicians India1995，43，： | 1 |
| 20 | N-policy for a machine repair system with spares and reneging显示文摘 | JAIN M Rakhee MAHESHWARI S | 2004 | Applied Mathematical Modeling2004，28，： | 1 |
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