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13篇 您的检索式：作者名="Jaime Guardia"

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		题名	作者	年代	出处	被引量
	1	通过手术导致的重量损失由胃绕过在疾病的肥胖的病人改进非含酒精的脂肪肝疾病显示文摘 AIM:To evaluate the effects of surgical weight loss(Roux-en-Y gastric bypass with a modified Fobi-Capella technique) on non alcoholic fatty liver disease in obese patients.METHODS:A group of 26 morbidly obese patients aged 45 ± 2 years and with a body mass index > 40 kg/m 2 who underwent open surgical weight loss operations had paired liver biopsies,the first at surgery and the second after 16 ± 3 mo of weight loss.Biopsies were evaluated and compared in a blinded fashion.The presence of metabolic syndrome,anthropometric and biochemical variables were also assessed at baseline and at the time of the second biopsy.RESULTS:Percentage of excess weight loss was 72.1% ± 6.6%.There was a reduction in prevalence of metabolic syndrome from 57.7%(15 patients) to 7.7%(2 patients)(P < 0.001).Any significance difference was observed in aspartate aminotransferase or alanine aminotransferase between pre and postsurgery.There were improvements in steatosis(P < 0.001),lobular(P < 0.001) and portal(P < 0.05) inflammation and fibrosis(P < 0.001) at the second biopsy.There were 25(96.1%) patients with non alcoholic steatohepatitis(NASH) in their index biopsy and only four(15.3%) of the repeat biopsies fulfilled the criteria for NASH.The persistence of fibrosis(F > 1) was present in five patients at second biopsy.Steatosis and fibrosis at surgery were predictors of significant fibrosis postsurgery.CONCLUSION:Restrictive mildly malabsorptive surgery provides significant weight loss,resolution of metabolic syndrome and associated abnormal liver histological features in most obese patients.	Víctor Vargas Helena Allende Albert Lecube Maria Teresa Salcedo Juan A Baena-Fustegueras José M Fort Joaquín Rivero Roser Ferrer Roberto Catalán Eva Pardina Santiago Ramón y Cajal Jaime Guardia Julia Peinado-Onsurbe	2012	World Journal of Hepatology2012，4，12：	6
	2	T cell responses and viral variability in blood donation candidates with occult hepatitis B infection显示文摘	Marta Bes Victor Vargas Maria Piron Natalia Casamitjana Juan Ignacio Esteban Nuria Vilanova Asuncion Pinacho Josep Quer Lluis Puig Jaime Guardia Silvia Sauleda	2011	Journal of Hepatology2011，，4：	2
	3	Predicting Early Mortality After Acute Variceal Hemorrhage Based on Classification and Regression Tree Analysis显示文摘	Salvador Augustin Laura Muntaner José T. Altamirano Antonio González Esteban Saperas Joan Dot Monder Abu–Suboh Josep R. Armengol Joan R. Malagelada Rafael Esteban Jaime Guardia Joan Genescà	2009	Clinical Gastroenterology and Hepatology2009，，12：	1
	4	Role of hepatitis B, C, and D viruses in dual and triple infection: Influence of viral genotypes and hepatitis B precore and basal core promoter mutations on viral replicative interference显示文摘	Rosendo Jardi Francisco Rodriguez Maria Buti Xose Costa Montserrat Cotrina Roman Galimany Rafael Esteban Jaime Guardia	2001	Hepatology2001，，2：	1
	5	Hemoperitoneum as a First Manifestation of Hepatocellular Carcinoma in Western Patients with Liver Cirrhosis显示文摘	Lluís Castells Margarita Moreiras Sergi Quiroga Agustí Alvarez-Castells Antonio Segarra Rafael Esteban Jaime Guardia	2001	Digestive Diseases and Sciences2001，，3：	1
	6	Hemoperitoneum as a First Manifestation of Hepatocellular Carcinoma in Western Patients with Liver Cirrhosis显示文摘	Lluís Castells Margarita Moreiras Sergi Quiroga Agustí Alvarez-Castells Antonio Segarra Rafael Esteban Jaime Guardia	2001	Digestive Diseases and Sciences2001，，3：	1
	7	Adrenomedullin, a Vasodilator Peptide Implicated in Hemodynamic Alterations of Liver Cirrhosis Relationship to Nitric Oxide显示文摘	Joan Genesca Antonio Gonzalez Roberto Catalan Rosa Segura Moises Martinez Rafael Esteban Roberto J. Groszmann Jaime Guardia	1999	Digestive Diseases and Sciences1999，，2：	1
	8	Predicting Early Mortality After Acute Variceal Hemorrhage Based on Classification and Regression Tree Analysis显示文摘	Salvador Augustin Laura Muntaner José T. Altamirano Antonio González Esteban Saperas Joan Dot Monder Abu–Suboh Josep R. Armengol Joan R. Malagelada Rafael Esteban Jaime Guardia Joan Genescà	2009	Clinical Gastroenterology and Hepatology2009，，12：	1
	9	Mutations in the basic core promoter region of hepatitis B virus. Relationship with precore variants and HBV genotypes in a Spanish population of HBV carriers显示文摘	Rosendo Jardi Francisco Rodriguez Maria Buti Xose Costa Auristela Valdes Helena Allende Melanie Schaper Roman Galimany Rafael Esteban Jaime Guardia	2003	Journal of Hepatology2003，，3：	1
	10	Hemoperitoneum as a First Manifestation of Hepatocellular Carcinoma in Western Patients with Liver Cirrhosis显示文摘	Lluís Castells Margarita Moreiras Sergi Quiroga Agustí Alvarez-Castells Antonio Segarra Rafael Esteban Jaime Guardia	2001	Digestive Diseases and Sciences2001，，3：	1
	11	Hemoperitoneum as a First Manifestation of Hepatocellular Carcinoma in Western Patients with Liver Cirrhosis显示文摘	Lluís Castells Margarita Moreiras Sergi Quiroga Agustí Alvarez-Castells Antonio Segarra Rafael Esteban Jaime Guardia	2001	Digestive Diseases and Sciences2001，，3：	1
	12	Rapid detection of lamivudine-resistant hepatitis B virus polymerase gene variants显示文摘	Rosendo Jardi Maria Buti Francisco Rodriguez-Frias Montserrat Cotrina Xose Costa Carles Pascual Rafael Esteban Jaime Guardia	1999	Journal of Virological Methods1999，，1：	1
	13	Hepatitis B virus infection: Precore mutants and its relation to viral genotypes and core mutations显示文摘	Francisco Rodriguez-Frias Maria Buti Rosendo Jardi Montserrat Cotrina Luis Viladomiu Rafael Esteban Jaime Guardia	1995	Hepatology1995，，6：	1

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