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7篇 您的检索式：作者名="Insuk Lee"

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		题名	作者	年代	出处	被引量
	1	Inhibition of pacemaker activity in interstitial cells of Cajal by LPS via NF-κB and MAP kinase显示文摘AIM:To investigate lipopolysaccharide(LPS) related signal transduction in interstitial cells of Cajal(ICCs) from mouse small intestine.METHODS:For this study,primary culture of ICCs was prepared from the small intestine of the mouse.LPS was treated to the cells prior to measurement of the membrane currents by using whole-cell patch clamp technique.Immunocytochemistry was used to examine the expression of the proteins in ICCs.RESULTS:LPS suppressed the pacemaker currents of ICCs and this could be blocked by AH6809,a prostaglandin E2-EP2 receptor antagonist or NG-Nitro-Larginine Methyl Ester,an inhibitor of nitric oxide(NO) synthase.Toll-like receptor 4,inducible NO synthase or cyclooxygenase-2 immunoreactivity by specific antibodies was detected on ICCs.Catalase(antioxidant agent) had no action on LPS-induced action in ICCs.LPS actions were blocked by nuclear factor kB(NF-kB) inhibitor,actinomycin D(a gene transcription inhibitor),PD 98059(a p42/44 mitogen-activated protein kinases inhibitor) or SB 203580 [a p38 mitogen-activated protein kinases(MAPK) inhibitor].SB 203580 also blocked the prostaglandin E2-induced action on pacemaker currents in ICCs but not NO.CONCLUSION:LPS inhibit the pacemaker currents in ICCs via prostaglandin E2-and NO-dependent mechanism through toll-like receptor 4 and suggest that MAPK and NF-kB are implicated in these actions.	Dong Chuan Zuo Seok Choi Pawan Kumar Shahi Man Yoo Kim Chan Guk Park Young Dae Kim Jun Lee In Yeoup Chang Insuk So Jae Yeoul Jun	2013	World Journal of Gastroenterology2013，19，8：	9
	2	TomatoNet A Genome-wide Co-functional Network for Unveiling Complex Traits of Tomato, a Model Crop for Fleshy Fruits显示文摘	Hyojin Kim Bong Suk Kim Jung Eun Shim Sohyun Hwang Sunmo Yang Eiru Kim Aniafi S. Iver-Pascuzzi2 Insuk Lee	2017	Molecular Plant2017，10，4：	1
	3	Synthesis of dimethyl carbonate by vapor phase oxidative carbonylation of methanol over Cubased catalysts 显示文摘	Man Seok Han Byung Gwon Lee Insuk Suh	2001	Joumal of Molecular Catalysis A: Chemical2001，170，：	1
	4	Bending quality of main Korean wood species 显示文摘	Hwang K Jung Insuk Lee Weonhee	2002	Wood Research2002，，89：	1
	5	Synthesis of dimethyl carbonate by vapor phase oxidative carbonylation of methanol over Cu- based catalysts显示文摘	Man Seok Han Byung Gwon Lee Insuk Suh	2001	Journal of Molecular Catalysis A: Chemical2001，170，12：	1
	6	Poncirus trifoliate fruit modulates pacemaker activity in interstitial cells of Cajal from the murine small intestine显示文摘	Byung Joo Kim Hyung Woo Kim Guem San Lee Seok Choi Jae Yeoul Jun Insuk So Seon Jeong Kim	2013	Journal of Ethnopharmacology2013，，3：	1
	7	WheatNet: a Genome-Scale Functional Network for Hexaploid Bread Wheat, Triticum aestivum显示文摘	Tak Lee Sohyun Hwang Chan Yeong Kim Hongseok Shim Hyojin Kim Pamela C. Ronald EdwardM. Marcotte Insuk Lee	2017	Molecular Plant2017，10，8：	0

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