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| 1 | Biodegradable stents in gastrointestinal endoscopy显示文摘Biodegradable stents(BDSs)are an attractive option to avoid ongoing dilation or surgery in patients with benign stenoses of the small and large intestines.The experience with the currently the only BDS for endoscopic placement,made of Poly-dioxanone,have shown promising results.However some aspects should be improved as are the fact that BDSs lose their radial force over time due to the degradable material,and that can cause stent-induced mucosal or parenchymal injury.This complication rate and modest clinical efficacy has to be carefully considered in individual patients prior to placement of BDSs.Otherwise,the price of these stents therefore it is nowadays an important limitation. | Vicente Lorenzo-Zú?iga Vicente Moreno-de-Vega Ingrid Marín Jaume Boix | 2014 | World Journal of Gastroenterology2014，20，9： | 10 |
| 2 | Protective effect of some vitamins against the toxic action of ethanol on liver regeneration induced by partial hepatectomy in rats显示文摘AIM: To investigate the effects of vitamins (A, C and E) on liver injury induced by ethanol administration during liver regeneration in rats. METHODS: Male Wistar rats subjected to 70% partial hepatectomy were divided into five groups (groups 1-5). During the experiment, animals of Group 1 drank only water. The other four groups (2-5) drank 30 mL of ethanol/L of water. Group 3 additionally received vitamin A, those of group 4 vitamin C and those of group 5 received vitamin E. Subsequently serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), albumin and bilirubin were measured colorimetrically. Lipid peroxidation (thiobarbituric-acid reactive substances, TBARS) both in plasma and liver was measured, as well as liver mass gain assessment and total DNA. RESULTS: Compared with sham group, serum AST and ALT increased significantly under ethanol treatment (43% and 93%, respectively, with P < 0.05). Vitamin C and vitamin E treatment attenuated the ethanol-induced increases in ALT and AST activity. Ethanol treatment also decreased serum albumin concentration compared to sham group (3.1 ± 0.4 g/dL vs 4.5 ± 0.2 g/dL; P < 0.05). During liver regeneration vitamins C and E significantly ameliorated liver injury for ethanol administration in hepatic lipid peroxidation (4.92 nmol/mg and 4.25 nmol/mg vs 14.78 nmol/mg, respectively, with P < 0.05). In association with hepatic injury, ethanol administration caused a significant increase in both hepatic and plasma lipid peroxidation. Vitamins (C and E) treatment attenuated hepatic and plasma lipid peroxidation. CONCLUSION: Vitamins C and E protect against liver injury and dysfunction, attenuate lipid peroxidation, and thus appear to be significantly more effective than vitamin A against ethanol-mediated toxic effects during liver regeneration. | Carlett Ramírez-Farías Eduardo Madrigal-Santillán José Gutiérrez-Salinas Nidia Rodríguez-Sánchez Maricela Martínez-Cruz Ilse Valle-Jones Ingrid Gramlich-Martínez Alejandra Hernández-Ceruelos José A Morales-González | 2008 | World Journal of Gastroenterology2008，14，6： | 8 |
| 3 | Aspects of the non-pharmacological treatment of irritable bowel syndrome显示文摘Irritable bowel syndrome(IBS) is one of the most commonly diagnosed gastrointestinal conditions. It represents a significant healthcare burden and remains a clinical challenge. Over the years IBS has been described from a variety of different perspectives; from a strict illness of the gastrointestinal tract(medical model) to a more complex multi-symptomatic disorder of the brain-gut axis(biopsychosocial/psychosomatic model). In this article we present aspects of the pathophysiology and the non-pharmacological treatment of IBS based on current knowledge. Effects of conditioned stress and/or traumatic influences on the emotional system(top-down) as well as effects on the intestine through stressors,infection,inflammation,food and dysbiosis(bottom-up) can affect braingut communication and result in dysregulation of the autonomic nervous system(ANS),playing an important role in the pathophysiology of IBS. Conditioned stress together with dysregulation of the autonomic nervous system and the emotional system may involve reactions in which the distress inside the body is not recognized due to low body awareness. This may explain why patients have difficulty identifying their symptoms despite dysfunction in muscle tension,movement patterns,and posture and biochemical functions in addition to gastrointestinal symptoms. IBS shares many features with other idiopathic conditions,such as fibromyalgia,chronic fatigue syndrome and somatoform disorders. The key to effective treatment is a thorough examination,including a gastroenterological examination to exclude other diseases along with an assessment of body awareness by a body-mind therapist. The literature suggests that early interdisciplinary diagnostic cooperation between gastroenterologists and body-mind therapists is necessary. Re-establishing balance in the ANS is an important component of IBS treatment. This article discusses the current knowledge of body-mind treatment,addressing the topic from a practical point of view. | Elsa Maria Eriksson Kristina Ingrid Andrén Goran Karl Kurlberg Henry Ture Eriksson | 2015 | World Journal of Gastroenterology2015，21，40： | 6 |
| 4 | Are we giving biologics too late? The case for early versus late use显示文摘Corticosteroids and immunomodulators have been the mainstay therapies for Crohn’s disease. Corticosteroids are highly effective to control symptoms in the short- term, but they are not effective in maintaining remission, they heal the mucosa in a reduced proportion of cases, and long-time exposure is associated with an increased risk of infections and mortality. Immunomodulators, azathioprine and methotrexate, heal the mucosa in a higher proportion of patients that corticosteroids but their onset of action is slow and they benefit less than half of patients with Crohn’s disease. In the last decade, medical therapy for Crohn’s disease has experienced a remarkable change due to the introduction of biologic therapy, and particularly the use of anti-tumour necrosis factor-alpha agents. Infliximab, adalimumab, and certolizumab pegol have demonstrated efficacy for induction and maintenance of remission in active Crohn’s disease. These agents have raised the bar for what is a suitable symptomatic response in Crohn’s disease and modification of the natural history of the disease has become a major goal in the treatment of Crohn’s disease. There are several data in the literature that suggest that early use of biologic therapy and achievement of mucosal healing contribute to disease course modification. However, many questions on early biological therapy for Crohn’s disease remain still unanswered. | Elena Ricart Orlando García-Bosch Ingrid Ordás Julián Panés | 2008 | World Journal of Gastroenterology2008，14，36： | 4 |
| 5 | Accuracy of Magnetic Resonance Enterography in Assessing Response to Therapy and Mucosal Healing in Patients With Crohn’s Disease显示文摘 | Ingrid Ordás Jordi Rimola Sonia Rodríguez José M. Paredes María J. Martínez-Pérez Esther Blanc Juan A. Arévalo Marta Aduna Montserrat Andreu Alexander Radosevic Anna M. Ramírez-Morros Susana Pinó Marta Gallego Aranzazu Jauregui-Amezaga Elena Ricart Julián | 2013 | Gastroenterology2013，，： | 3 |
| 6 | Risk of developing tuberculosis under anti-TNF treatment despite latent infection screening显示文摘 | Aranzazu Jauregui-Amezaga Fanny Turon Ingrid Ordás Marta Gallego Faust Feu Elena Ricart Julián Panés | 2012 | Journal of Crohn’s and Colitis2012，，： | 2 |
| 7 | State of the art on high temperature thermal energy storage for power generation. Part 1—Concepts, materials and modellization显示文摘 | Antoni Gil Marc Medrano Ingrid Martorell Ana Lázaro Pablo Dolado Belén Zalba Luisa F. Cabeza | 2009 | Renewable and Sustainable Energy Reviews2009，，1： | 2 |
| 8 | State of the art on high temperature thermal energy storage for power generation. Part 1—Concepts, materials and modellization显示文摘 | Antoni Gil Marc Medrano Ingrid Martorell Ana Lázaro Pablo Dolado Belén Zalba Luisa F. Cabeza | 2009 | Renewable and Sustainable Energy Reviews2009，，1： | 2 |
| 9 | Characteristics of an inducible cell-free antibacterial reaction in hemolymph of Samiacynthia pupae 显示文摘 | Boman H G Ingrid N F Kerstin P | 1974 | Infect Immun1974，10，： | 1 |
| 10 | The acid and alkaline solubilization process for the isolation of muscle proteins : state of the art 显示文摘 | Helgi N Ingrid U | 2009 | Food Bioprocess Technology2009，2，1： | 1 |
| 11 | Cephalometric features of filipions with angle class I occlusion according to the Munich analysis显示文摘 | Marian A Sevilla N Ingrid R J | 2004 | Angle Orthod2004，75，1： | 1 |
| 12 | Promoter analysis of the ehaleone synthase (chsA) gene of Petunia hybrid:a 67 bp promoter region directs flower-specific expression 显示文摘 | Ingrid M vander M Cornelis E Spelt J N | 1990 | Plant Molecular Biology1990，15，： | 1 |
| 13 | State of the art on high temperature thermal energy storage for power generation. Part 1—Concepts, materials and modellization显示文摘 | Antoni Gil Marc Medrano Ingrid Martorell Ana Lázaro Pablo Dolado Belén Zalba Luisa F. Cabeza | 2009 | Renewable and Sustainable Energy Reviews2009，，1： | 1 |
| 14 | Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics显示文摘 | INGRID Y L BI X N | 2003 | Proe Natl Ac ad Sci USA2003，100，14： | 1 |
| 15 | On-line preconcentration and speciation of arsenic by flow injection hydride generation atomic absorption spectrophotometry显示文摘 | CRISTINE INGRID S LILIBETH DLC N COO FLORIAN R | 2005 | Talanta2005，68，： | 1 |
| 16 | Proteolytic activity in enzymatic extracts from Carica papaya L. cv. Maradol harvest by-products显示文摘 | Galindo-Estrella Thomás Hernández-Gutiérrez Rodolfo Mateos-Díaz Juan Sandoval-Fabián Georgina Chel-Guerrero Luis Rodríguez-Buenfil Ingrid Gallegos-Tintoré Santiago | 2008 | Process Biochemistry2008，，1： | 1 |
| 17 | Volumetric and dosimetrie evalu- ation of radiation treatment planning:radiation conformity index 显示文摘 | Tommy K Ingrid K Per N | | Int J Radiat Oncol Bid Phys0，42，5： | 1 |
| 18 | Fatal West Nile Virus Infection After Probable Transfusion-Associated Transmission - Colorado, 2012显示文摘 | Kelly Sharon Le Tuan N Brown Jennifer A Lawaczek Elisabeth W Kuehnert Matthew Rabe Ingrid B Staples J Erin Fischer Marc | 2013 | MMWR Morbidity and Mortality Weekly Report2013，，31： | 1 |
| 19 | Promoter analysis of the chalcone synthase (chsA) gene of Petunia hybrida:a 67 bp promoter region directs flower specific expression显示文摘 | Cornelis E Spelt Josph N M Mol | 1990 | Plant Mol Biol1990，15，： | 1 |
| 20 | Analysis of the p53 tumor suppressor gene in rheumatoid arthritis synovial fibroblasts显示文摘 | Frank K Martin J Ingrid N | 1999 | Arthritis Rheum1999，42，： | 1 |
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