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| 1 | Possible role of human cytomegalovirus in pouchitis after proctocolectomy with ileal pouch-anal anastomosis in patients with ulcerative colitis显示文摘AIM: To detect the presence of human cytomegalovirus (HCMV) proteins and genes on the ileal pouch of patients with ulcerative colitis who have undergone proctocolectomy with ileal pouch-anal anastomosis (iPAA). METHODS: immunohistochemistry, polymerase chain reaction (PCR) and PCR sequencing methods were utilized to test the presence of HCMV in pouch specimens taken from 34 patients in 86 endoscopies. RESULTS: HCMV genes and proteins were detected in samples from 12 (35.2%) patients. The rate of detection was significant in the endoscopies from patients diagnosed with pouchitis (5 of 12, 41.6%), according to the Japanese classification of pouchitis, in comparison to patients with normal pouch (7 of 62, 11.2%; P = 0.021). in all patients with pouchitis in which the HCMV was detected, it was the first episode of pouchitis. The virus was not detected in previous biopsies taken in normal endoscopies of these patients. During the follow- up, HCMV was detected in one patient with recurrent pouchitis and in 3 patients whose pouchitis episodes improved but whose positive endoscopic findings persisted. CONCLUSION: HCMV can take part in the inflammatory process of the pouch in some patients with ulcerative colitis who have undergone proctocolectomy with iPAA. | Damian Casadesus Tatsuo Tani Toshifumi Wakai Satoshi Maruyama Tsuneo iiai Haruhiko Okamoto Katsuyoshi Hatakeyama | 2007 | World Journal of Gastroenterology2007，13，7： | 4 |
| 2 | Clinical benefit of surgery for stage IV colorectal cancer with synchronous peritoneal metastasis显示文摘 | Hirotoshi Kobayashi Kenjiro Kotake Kimihiko Funahashi Kazuo Hase Koichi Hirata Tsuneo Iiai Shingo Kameoka Yukihide Kanemitsu Koutarou Maeda Akihiko Murata Masayuki Ohue Kazuo Shirouzu Keiichi Takahashi Toshiaki Watanabe Hideaki Yano Toshimasa Yatsuoka Yoj | 2014 | Journal of Gastroenterology2014，，4： | 2 |
| 3 | Increase in the proportion of granulated CD56^+ T cells in patients with malignancy显示文摘 | Takii Y Hashimoto S Iiai T | 1994 | Clin Exp Immunol1994，97，3： | 1 |
| 4 | Ontogeny and development of extrathymic T cells in mouse liver 显示文摘 | Iiai T Watanabe H Seki S | 1992 | Immunology1992，77，4： | 1 |
| 5 | Requirement of IL-4 and liver NK1+T cells for concanavalin A-induced hepatic injury in mice显示文摘 | Toyabe S Seki S Iiai T | 1997 | J Immunol1997，159，3： | 1 |
| 6 | Prognostic Groups in Colorectal Carcinoma Patients Based on Tumor Cell Proliferation and Classification and Regression Tree (CART) Survival Analysis显示文摘 | Vladimir A. Valera MD PhD Beatriz A. Walter MD PhD Naoyuki Yokoyama MD PhD Yu Koyama MD PhD Tsuneo Iiai MD PhD Haruhiko Okamoto MD PhD Katsuyoshi Hatakeyama MD PhD FACS | 2007 | Annals of Surgical Oncology2007，，1： | 1 |
| 7 | Common carotid arterial thrombosis associated with ulcerative colitis显示文摘A 26-year-old woman with ulcerative colitis was transferred to our hospital with left hemiparesis due to cerebral infarction. Cervical ultrasonography and magnetic resonance imaging angiography revealed thrombosis at the right common carotid artery and the right internal carotid artery. Antithrombotic and anticoagulant therapies were commenced. After about 2 wk of the treatment, the frequency of her diarrhea increased. She underwent emergency subtotal colectomy, but 10 d later an abundant hemorrhage from the remnant rectum occurred, so the remnant rectum was resected and an ileal pouch anal anastomosis was performed. Antithrombotic and anticoagulant therapies were continued, but neither her neurological status nor magnetic resonance imaging angiography findings showed subsequent changes. She was discharged 3 mon after operation. This is a rare case of common carotid arterial thrombosis occurring as a complication of ulcerative colitis, in which antithrombotic and anticoagulant therapies are considered to provoke a deterioration of the patient’s bowel disease. | Hitoshi Nogami Tsuneo Iiai Satoshi Maruyama Tatsuo Tani Katsuyoshi Hatakeyama | 2007 | World Journal of Gastroenterology2007，13，11： | 1 |
| 8 | Increase in the proportion of granulated CD56+ T cells in patients with malignancy显示文摘 | Takii Y Hashimoto S Iiai T | 1994 | Clin Exp Immunol1994，97，3： | 1 |
| 9 | Toxic megacolon associated with cytomegalovirus infection in ulcerative colitis显示文摘 | Yoshifumi Shimada Tsuneo Iiai Haruhiko Okamoto Takeyasu Suda Katsuyoshi Hatakeyama Terasu Honma Yoichi Ajioka | 2003 | Journal of Gastroenterology2003，，11： | 1 |
| 10 | Requirement of IL-4 and liver NK ^+ T cells for concanavalin A-induced hepatic injury in mice显示文摘 | Toyabe S Seki S Iiai T | 1997 | J Immunol1997，159，： | 1 |
| 11 | Identification of nico-tinic acetylcholine receptors on lymphocytes in peripheryas well as thymus in mice显示文摘 | Toyabe S Iiai T Fukuda M | 1997 | Immunology1997，92，： | 1 |
| 12 | Comuted tomography as a guide in the dignosis and follow-up of brain abscesses显示文摘 | Whelan MA H IIaI SK | | Radiology0，135，： | 1 |
| 13 | 香蕉酸奶对付花粉症显示文摘又要到了花粉症的季节。酸奶能有效缓解症状,让我们从现在就开始吧。使酸奶发挥效果有三招。聪明吃起来,轻松度过这个最艰难的季节! | sadasetsuko iiai(插图) | 2020 | 健康与美容2020，0，1： | 0 |
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