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7篇 您的检索式：作者名="ISHII Nobuo"

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		题名	作者	年代	出处	被引量
	1	Cell sheet technology for regeneration of esophageal mucosa显示文摘The progress of tissue-engineering technology has realized development of new therapies to treat various disorders by using cultured cells. Cell-and tissue-based therapies have been successfully applied to human patients, and several tissue-engineered products have been approved by the regulatory agencies and are commercially available. In the review article, we describe our experience of development and clinical application of cell sheet-based regenerative medicine.Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) have been shown to be useful for removal of gastrointestinal neoplasms with less invasiveness compared with open surgery, especially in esophageal surgery. However, postoperative inflammation and stenosis are major complications observed after intensive mucosal resection. Therefore, we have developed novel regenerative medicine to prevent such complications and promote wound healing of esophageal mucosa after EMR or ESD. Transplantable oral mucosal epithelial cell sheets were fabricated from patients' own oral mucosa. Immediately after EMR or ESD, fabricated autologous cell sheets were endoscopically transplanted to the ulcer sites. We performed a preclinical study with a canine model. In human clinical settings, cell culture and cell sheet fabrication were performed in clean rooms according to good manufacturing practice guidelines, and pharmaceutical drugs were used as supplements to culture medium in place of research regents used in animal study. We believe that cell-based regenerative medicine would be useful to improve quality of life of patients after EMR or ESD.	Ryo Takagi Masayuki Yamato Nobuo Kanai Daisuke Murakami Makoto Kondo Takaaki Ishii Takeshi Ohki Hideo Namiki Masakazu Yamamoto Teruo Okano	2012	World Journal of Gastroenterology2012，18，37：	9
	2	Phase Singularities in Analytic Signal of White-light Speckle Pat- tern with Application to Micro-displacement Measurement 显示文摘	WANG Wei ISHII Nobuo HANSON Steen G	2005	Optics Communications2005，248，123：	1
	3	High-efficiency recovery of target cells using improved yeast display system for detection of protein–protein interactions显示文摘	Nobuo Fukuda Jun Ishii Seiji Shibasaki Mitsuyoshi Ueda Hideki Fukuda Akihiko Kondo	2007	Applied Microbiology and Biotechnology2007，，1：	1
	4	Full-line or specialization strategy? The negative effect of product variety on product line strategy显示文摘	Nobuo Matsubayashi Yasuaki Ishii Kentaro Watanabe Yoshiyasu Yamada	2008	European Journal of Operational Research2008，，2：	1
	5	Optical properties of epitaxial plzt thin films显示文摘	Nobuo Kamehara Masatoshi Ishii Keisuke Sato Kazuaki Kurihara Masao Kondo	2008	Journal of Electroceramics2008，，1：	1
	6	Down-Regulation of DUSP6 Expression in Lung Cancer显示文摘	Koji Okudela Takuya Yazawa Tetsukan Woo Masashi Sakaeda Jun Ishii Hideaki Mitsui Hiroaki Shimoyamada Hanako Sato Michihiko Tajiri Nobuo Ogawa Munetaka Masuda Takashi Takahashi Haruhiko Sugimura Hitoshi Kitamura	2009	The American Journal of Pathology2009，，2：	1
	7	Flavonoid glycosides and limonoids from Citrus molasses显示文摘	Masanori Kuroyanagi Hiromi Ishii Nobuo Kawahara Hiroyuki Sugimoto Hideo Yamada Kiyoshi Okihara Osamu Shirota	2008	Journal of Natural Medicines2008，，1：	1

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