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148篇 您的检索式：作者名="Hyttel"

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	题名	作者	年代	出处	被引量
1	Enrichment of retinal ganglion and Müller glia progenitors from retinal organoids derived from human induced pluripotent stem cells-possibilities and current limitations显示文摘BACKGROUND Retinal organoids serve as excellent human-specific disease models for conditions affecting otherwise inaccessible retinal tissue from patients.They permit the isolation of key cell types affected in various eye diseases including retinal ganglion cells(RGCs)and Müller glia.AIM To refine human-induced pluripotent stem cells(hiPSCs)differentiated into threedimensional(3D)retinal organoids to generate sufficient numbers of RGCs and Müller glia progenitors for downstream analyses.METHODS In this study we described,evaluated,and refined methods with which to generate Müller glia and RGC progenitors,isolated them via magnetic-activated cell sorting,and assessed their lineage stability after prolonged 2D culture.Putative progenitor populations were characterized via quantitative PCR and immunocytochemistry,and the ultrastructural composition of retinal organoid cells was investigated.RESULTS Our study confirms the feasibility of generating marker-characterized Müller glia and RGC progenitors within retinal organoids.Such retinal organoids can be dissociated and the Müller glia and RGC progenitor-like cells isolated via magnetic-activated cell sorting and propagated as monolayers.CONCLUSION Enrichment of Müller glia and RGC progenitors from retinal organoids is a feasible method with which to study cell type-specific disease phenotypes and to potentially generate specific retinal populations for cell replacement therapies.	Kristine Karla Freude Sarkis Saruhanian Alanna McCauley Colton Paterson Madeleine Odette Annika Oostenink Poul Hyttel Mark Gillies Henriette Haukedal Miriam Kolko	2020	World Journal of Stem Cells2020，12，10：	2
2	Bovine oocyte diameter in relation to maturational competence and transcriptional activity 显示文摘	Fair T Hyttel P Greve T	1995	Mol Reprod Dev1995，42，：	1
3	Somatic cell cloning without micromanipulators 显示文摘	VAJTA G LEWISI W HYTTEL P	2001	Cloning2001，3，2：	1
4	Somatic cell cloning without micromanipulators显示文摘	Gabor Vajta Ian M Lewis Poul Hyttel	2001	Cloning2001，3，2：	1
5	The pharmacology of citalopram显示文摘	Hyttel J Amt J Sanchez C	1995	Rev Contemop Pharmacother1995，6，2：	1
6	Regulation of H3K27me3 and H3K4me3 during early porcine embryonic development显示文摘	Gao Y Hyttel P Hall VJ		0，，06：	1
7	Increased blastocyst formation of cloned porcine embryos produced with donor cells pre-treated with Xenopus egg extract and/or digitonin显示文摘	Ying Liu Olga ?strup Juan Li Gábor Vajta Lin Lin Peter M. Kragh Stig Purup Poul Hyttel Henrik Callesen	2011	Zygote2011，，1：	1
8	Erythropoietin treatment atleviates ultrastructural myelin changes induced by murine cerebral malaria显示文摘	Hempel C Hyttel P Staalso T	2012	Malar J2012，11，：	1
9	The pharmacology of citalopram 显示文摘	Hyttel J Arnt J Sanchez C	1995	Rev Contemp Pharmacother1995，6，3：	1
10	Morphological assessment of preimplantation embryo quality in cattle显示文摘	Maddox - Hyttell P Gjorret JO Vajta G	2003	Reprod Suppl2003，61，：	1
11	Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding显示文摘	SANCHEZ C HYTTEL J	1999	Cell Mol Neurobiol1999，19，4：	1
12	Regulation of H3k27me3and H3k4me3during early porcine embry-onic development显示文摘	GAO Y HYTTEL P HALL V J	2010	Mol Reprod Dev2010，77，6：	1
13	Vitrification of bovine oocytes with the open pulled straw method: ultrastruetural consequences 显示文摘	Hyttel P Vajta G Callesen H	2000	Mol Reprod Dev2000，56，：	1
14	Immunolocalization of nucleolar proteins during bovine oocyte growth, meiotic maturation and fertilization显示文摘	Fair T Hyttel P Lonergan P	2001	Biol Reprod2001，64，：	1
15	Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs)显示文摘	HYTTEL J	1994	Int Clin Psychopharmacol1994，9，1：	1
16	Somatic cell cloning without micromanipulators显示文摘	VAJTA G LEWIS I M HYTTEL P	2001	Cloning2001，3，2：	1
17	Ribosomal RNA gene expression and chromosome aberrations in bovine oocytes and preimplantation embryos 显示文摘	Hyttel P Viuff D Fair T	2001	Reproduction2001，122，：	1
18	Maintenance of meiotic arrest in bovine oocytes in vitro using butyrolactone Ⅰ:effects on oocyte ultrastructure and nucleolus function显示文摘	Fair T Hyttel PM Motlik J	2002	Mol Reprod Dev2002，62，3：	1
19	Risks of in-vitro producton of cattle and swine embryos:aberrations in chromosome numbers,ribosomal RNA gene activation and perinatal physiology显示文摘	Hyttel P Viuff D Laurincik J	2000	Hum Reprod2000，15，5：	1
20	Somatic cell cloning without micromanipulators显示文摘	VAJTA G LEWIS I M HYTTEL P	2001	Cloning2001，3，2：	1

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