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| 1 | Salt effects on shoot growth and essential oil yield and composition in safflower (Carthamus tinctorius L.)显示文摘 | Jamel Harrathi Houneida Attia Manel Neffati Karim Hosni Brahim Marzouk Moktar Lachaal Najoua Karray-Bouraoui | 2013 | Journal of Essential Oil Research2013，，6： | 1 |
| 2 | Physiological Responses of Pea Plants to Salinity and Gibberellic Acid显示文摘Pea is a seed legume.It is rich in cellulose fibre and protein.It is also a significant source of minerals and vitamins.In this paper,we set out to better characterize the physiological responses of Pisum sativum L.to the combined effects of NaCl,100 mM and gibberellins(GA3).Our analysis revealed that NaCl caused a decrease in growth resulting in a reduction in root elongation,distribution and density,leaf number and leaf area,and a decrease in dry matter of roots and shoots.However,the contribution of GA3 in the salty environment induced an increase in these different parameters suggesting an improving effect of this hormone on growth of pea in presence of salt.NaCl also led to a disturbance of the photosynthetic machinery.Indeed,level of chlorophyll pigments(a and total)and photosynthetic activity were decreased compared to the control plants.However,the exogenous supply of GA3 restored this decrease in net CO_(2) assimilation,but not in chlorophyll content.Additional analyses were performed on the effect of salinity/GA3 interaction on osmolytes(soluble sugars and starch).Our results showed an increase in sugars and a decrease in starch in the presence of 100 mM NaCl.The salt-GA3 combination resulted in compensation of soluble sugar contents but not of starch contents,suggesting a beneficial effect of GA3 under saline stress conditions.Level of three main polyamines putrescine,spermidine,and spermine increased significantly in all organs of salt-treated plants. | Houneida Attia | 2023 | Phyton-International Journal of Experimental Botany2023，92，1： | 0 |
| 3 | Severe hemorrhagic colitis in a patient with chronic myeloid leukemia in the blastic phase after dasatinib use显示文摘Dasatinib is a second-line tyrosine kinase inhibitor used in patients with imatinib resistant or intolerant chronic myeloid leukemia (CML) and Philadelphia chromosomepositive acute leukemia. Gastrointestinal bleeding may occur in up to 7% of patients using dasatinib, although, severe dasatinib-related acute colitis had rarely been reported. Here, we present the case of a 36-year-old female who progressed to acute myeloid leukemia after fourteen months of receiving imatinib for CML in the chronic phase and was treated with a dasatinib-containing chemotherapy regimen. On day 34 of treatment, the patient developed moderate abdominal pain and bloody diarrhea with mucous. Analyses of stool specimens were negative for parasites, Clostridium difficile , and other pathogenic bacteria. The cytomegalovirus pp65 antigen was negative in her blood leukocytes. A colonoscopy revealed acute colitis, and a mucosal biopsy showed nonspecific colitis. The patient was treated with broad-spectrum antibiotics, bowel rest and hydration, and dasatinib treatment was stopped. Her bloody diarrhea improved within 72 h. After confirming cytological remission, the patient received initial course of consolidation, and dasatinib treatment was reinstated. However, hemorrhagic colitis recurred. After discontinuing dasatinib, herhemorrhagic colitis drastically improved and did not recur following the administration of nilotinib. The characteristics of our patient suggest that dasatinib treatment can lead to hemorrhagic colitis, which typically resolves after discontinuation of the drug. | Zahra Kmira Ben Sayed Nesrine Zaghouani Houneida Ben Fredj Wafa Slama Aida Ben Youssef Yosra Zaier Monia Badreddine Sriha Khelif Abderrahim | 2013 | World Journal of Gastrointestinal Pathophysiology2013，4，3： | 0 |
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