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| 1 | HYDRODYNAMIC AND ELASTOHYDRODYNAMIC STUDIES OF A CYLINDRICAL JOURNAL BEARING显示文摘In this article,the effect of the bearing elastic deformation on the performance characteristics of a cylindrical journal bearing is analyzed.The variety of simulation models covers hydrodynamic(HD) and elastohydrodynamic(EHD) lubrication theories.The Reynolds equations governing the flow in the clearance space of the journal bearing are obtained by considering the effect of mass transfer across the fluid film.The finite element method with an iteration scheme was employed to solve both the Reynolds equation and the three-dimensional elasticity equation representing the displacement field in the bearing shell.The converged solutions for the lubricant flow and elastic deformation vector are obtained.Dynamic characteristics of the journal bearing are computed for HD and EHD theories.Numerical simulation results show that the flexibility of bearing liner has a significant influence on the performance of a cylindrical journal bearing.Indeed,the elastic deformations of the bearing liner extend the pressure area in the bearing and increase the minimum film thickness.Although,dynamic coefficient,load capacity and attitude angle decrease. | ATTIA HILI Molka BOUAZIZ Slim MAATAR Mohamed FAKHFAKH Tahar HADDAR Mohamed | 2010 | Journal of Hydrodynamics2010，22，2： | 12 |
| 2 | Assessment of KL-6 as a tumor marker in patients with hepatocellular carcinoma显示文摘AIM: To investigate the clinical significance of KL-6 as a tumor marker of HCC in two different ethnic groups with chronic liver disease consecutively encountered at outpatient clinics.METHODS: Serum KL-6 was measured by the sandwich enzyme immunoassay method using the KL-6 antibody (Ab) as both the capture and tracerAb according to the manufacturer's instructions (Eisai, Tokyo, Japan).Assessment of alpha fetoprotein (AFP) and protein induced vitamin K deficiency or absence (PIVKA-Ⅱ) was performed in both groups using commercially available kits.RESULTS: A significantly higher mean serum KL-6(556±467 U/L) was found in HCC in comparison with non-HCC groups either with (391±176 U/L; P<0.001)or without (361±161 U/L; P<0.001) liver cirrhosis (LC).Serum KL-6 level did not correlate with either AFP or PIVKA-Ⅱ serU/Levels. Using receiver operating curve analysis for KL-6 as a predictor for HCC showed that the area under the curve was 0.574 (95%CI = 0.50-0.64)and the KL-6 level that gave the best sensitivity (61%) was found to be 334 U/L but according to the manufacturer's instructions; a cut-off point of 500 U/Lwas used that showed the highest specificity (80%)in comparison with AFP and PIVKA-Ⅱ (78% vs 72%respectively). Combining the values of the three markers improved specificity of AFP for HCC diagnosis from 78%for AFP alone; 93% for AFP plus PIVKA-Ⅱ to 99% for both plus KL-6 value (P<0.001). Mean serum alkaline phosphatase level was significantly higher in KL-6positive (564±475) in comparison with KL-6 negative (505±469) HCC patients (P = 0.021), but such a difference was not found among non-HCC corresponding groups.CONCLUSION: KL-6 is suggested as a tumor for HCC.Its positivity may reflect HCC-associated cholestasis and/or local tumor invasion. | Amal Gad Eiji Tanaka Akihiro Matsumoto Moushira Abd-el Wahab Abd el-Hamid Serwah Fawzy Attia Khalil Ali Howayda Hassouba Abd el-Raoof el-Deeb Tetsuya Ichijyo Takeji Umemura Hidetomo Muto Kaname Yoshizawa Kendo Kiyosawa | 2005 | World Journal of Gastroenterology2005，11，42： | 8 |
| 3 | Doppler ultrasonography in living donor liver transplantation recipients: Intra- and post-operative vascular complications显示文摘Living-donor liver transplantation has provided a solution to the severe lack of cadaver grafts for the replacement of liver afflicted with end-stage cirrhosis, fulminant disease, or inborn errors of metabolism. Vascular complications remain the most serious complications and a common cause for graft failure after hepatic transplantation. Doppler ultrasound remains the primary radiological imaging modality for the diagnosis of such complications. This article presents a brief review of intra- and post-operative living donor liver transplantation anatomy and a synopsis of the role of ultrasonography and color Doppler in evaluating the graft vascular haemodynamics both during surgery and post-operatively in accurately defining the early vascular complications. Intra-operative ultrasonography of the liver graft provides the surgeon with useful real-time diagnostic and staging information that may result in an alteration in the planned surgical approach and corrections of surgical complications during the procedure of vascular anastomoses. The relevant intraoperative anatomy and the spectrum of normal and abnormal findings are described. Ultrasonography and color Doppler also provides the clinicians and surgeons early post-operative potential developmental complications that may occur during hospital stay. Early detection and thus early problem solving can make the difference between graft survival and failure. | Omar Abdelaziz Hussein Attia | 2016 | World Journal of Gastroenterology2016，22，27： | 8 |
| 4 | 环境变化对中亚干旱区水储量变化的影响(英文)显示文摘The spatio-temporal pattern of the global water resource has significantly changed with climate change and intensified human activities. The regional economy and ecological environment are highly affected by terrestrial water storage(TWS), especially in arid areas. To investigate the response relationships between TWS and changing environments(climate change and human activities) in Central Asia, we used the Gravity Recovery and Climate Experiment(GRACE) data, Climatic Research Unit(CRU) climate data and Moderate Resolution Imaging Spectroradiometer(MODIS) remote sensing data products(MOD16A2, MOD13A3 and MCD12Q1) from 2003 to 2013, as well as the slope and Pearson correlation analysis methods. Results indicate that:(1) TWS in about 77% of the study area decreased from 2003 to 2013. The total change volume of TWS is about 2915.6 × 108 m^3. The areas of decreased TWS are mainly distributed in the middle of Central Asia, while the areas of increased TWS are concentrated in the middle-altitude regions of the Kazakhstan hills and Tarim Basin.(2) TWS in about 5.91% of areas, mainly distributed in the mountain and piedmont zones, is significantly positively correlated with precipitation, while only 3.78% of areas show significant correlation between TWS and temperature. If the response time was delayed by three months, there would be a very good correlation between temperature and TWS.(3) There is a significantly positive relationship between TWS and Normalized Difference Vegetation Index(NDVI) in 13.35% of the study area.(4) The area of significantly positive correlation between TWS and evapotranspiration is about 31.87%, mainly situated in mountainous areas and northwestern Kazakhstan. The reduction of regional TWS is related to precipitation more than evaporation. Increasing farmland area may explain why some areas show increasing precipitation and decreasing evapotranspiration.(5) The influences of land use on TWS are still not very clear. This study could provide scientific data useful for the estimation of changes in TWS with climate change and human activities. | 胡伟杰 刘海隆 包安明 Attia M.EL-TANTAWI | 2018 | Journal of Geographical Sciences2018，28，7： | 7 |
| 5 | Child-Pugh-Turcott versus Meld score for predicting survival in a retrospective cohort of black African cirrhotic patients显示文摘AIM: To compare the performance of the Child-Pugh-Turcott (CPT) score to that of the model for end-stage liver disease (MELD) score in predicting survival of a retrospective cohort of 172 Black African patients with cirrhosis on a short and mid-term basis.METHODS: Univariate and multivariate (Cox model) analyses were used to identify factors related to mortality. Relationship between the two scores was appreciated by calculating the correlation coefficient. The Kaplan Meier method and the log rank test were used to elaborate and compare survival respectively. The Areas Under the Curves were used to compare the performance between scores at 3, 6 and 12 mo.RESULTS: The study population comprised 172 patients, of which 68.9% were male. The mean age of the patient was 47.5 ± 13 years. Hepatitis B virus infection was the cause of cirrhosis in 70% of the cases. The overall mortality was 31.4% over 11 years of follow up. Independent factors significantly associated with mortality were: CPT score (HR = 3.3, 95% CI [1.7-6.2]) (P < 0.001) (stage C vs stage A-B); Serum creatine (HR = 2.5, 95% CI [1.4-4.3]) (P = 0.001) (Serum creatine > 1.5 mg/dL versus serum creatine < 1.5 mg/dL); MELD score (HR = 2.9, 95% CI [1.63-5.21]) (P < 0.001) (MELD > 21 vs MELD < 21). The area under the curves (AUC) that predict survival was 0.72 and 0.75 at 3 mo (P = 0.68), 0.64 and 0.62 at 6 mo (P = 0.67), 0.69 and 0.64 at 12 mo (P = 0.38) respectively for the CPT score and the MELD score.CONCLUSION: The CPT score displays the sameprognostic significance as does the MELD score in black African patients with cirrhosis. Moreover, its handling appears less cumbersome in clinical practice as compared to the latter. | KA Attia KC Ackoundou-N'guessan AT N’dri-yoman AK Mahassadi E Messou YF Bathaix YH Kissi | 2008 | World Journal of Gastroenterology2008，14，2： | 5 |
| 6 | Optimization of biliary drainage in inoperable distal malignant strictures显示文摘BACKGROUND Given most patients with distal malignant biliary obstruction present in the nonresectable stage,palliative endoscopic biliary drainage with fully covered metal stent(FCMS)or uncovered metal stent(UCMS)is the only available measure to improve patients’quality of life.Half covered metal stent(HCMS)has been recently introduced commercially.The adverse effects and stent function between FCMS and UCMS have been extensively discussed.AIM To study the duration of stent patency of HCMS and compare it with FCMS and UCMS to optimize biliary drainage in inoperable patients with distal malignant obstruction.Secondary aims in our study included evaluation of patients’survival and the rates of adverse events for each type of stent.METHODS We studied 210 patients and randomized them into three equal groups;HCMS,FCMS and UCMS were inserted endoscopically.RESULTS Stent occlusion occurred in(18.6%,17.1%and 15.7%in HCMS,FCMS and UCMS groups,respectively,P=0.9).Stent migration occurred only in patients with FCMS(8.6%of patients).Cholangitis and cholecystitis occurred in 11.4%and 5.7%of patients,respectively,in FCMS.Tumor growth occurred only in 10 cases among patients with UCMS after a median of 140 d,sludge occurred in nine,seven and one patients in HCMS,FCMS and UCMS,respectively(P=0.04).CONCLUSION Given the prolonged stent functioning time,the use of HCMS is preferred over the use of UCMS and FCMS for optimizing biliary drainage in patients with distal malignant biliary obstruction. | Esam Elshimi Wesam Morad Omar Elshaarawy Ahmed Attia | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，9： | 5 |
| 7 | Hepatocellular carcinoma in Egypt: A single center study over a decade显示文摘AIM: To identify the trend, possible risk factors and any pattern change of hepatocellular carcinoma (HCC) in Egyptover a decade.METHODS: All HCC patients attending Cairo Liver Center between January 1993 and December 2002, were enrolledin the study. Diagnosis of HCC was based on histopath ological examination and/or detection of hepatic focal lesions by two imaging techniques plus α-fetoprotein level above 200 ng/mL. The duration of the study was divided into two periods of 5 years each; period Ⅰ (1993-1997) and period Ⅱ (1998-2002). Trend, demographic features of patients (age, gender, and residence), risk factors (HBsAg,HCV-Ab, schistosomiasis and others) and pattern of the focal lesions were compared between the two periods.Logistic regression model was fitted to calculate the adjusted odds ratios for the potential risk factors. The population attributable risk percentage was calculated to estimate the proportion of HCC attributed to hepatitis B and C viral infections.RESULTS: Over a decade, 1 328 HCC patients out of 22 450 chronic liver disease (CLD) patients were diagnosed with an overall proportion of 5.9%. The annual proportion of HCC showed a significant rising trend from 4.0% in 1993 to 7.2% in 2002 (P = 0.000). A significant increase in male proportion from 82.5% to 87.6% (P = 0.009); M/F from 5:1 to 7:1 and a slight increase of the predominant age group (40-59 years) from 62.6% to 66.8% (P = 0.387)in periods Ⅰ and Ⅱ respectively, reflecting a shift to younger age group. In the bivariate analysis, HCC was significantly higher in rural residents, patients with history of schistosomiasis and/or blood transfusion. Yet, after adjustment, these variables did not have a significant risk for development of HCC. There was a significant decline of HBsAg from 38.6% to 20.5% (P = 0.000), and a slight increase of HCV-Ab from 85.6% to 87.9% in periods Ⅰ and Ⅱ respectively. HBV conferred a higher risk to develop HCC more than HCV in period Ⅰ (OR 1.9 vs 1.6) and period Ⅱ (OR 2.7 vs 2.0), but the relative contribution of HBV for development of HCC declined in period Ⅱ compared to period Ⅰ (PAR% 4.2%, 21.32%). At presentation,diagnostic α-fetoprotein level (≥200 ng/mL) was demonstrated in 15.6% vs28.9% and small HCC (≤3 cm)represented 14.9% vs 22.7% (P = 0.0002) in periods Ⅰ and Ⅱ respectively.CONCLUSION: Over a decade, there was nearly a twofold increase of the proportion of HCC among CLD patients in Egypt with a significant decline of HBV and slight increase of HCV as risk factors. α-Fetoprotein played a limited role in diagnosis of HCC, compared to imaging techniques.Increased detection of small lesions at presentation reflects increased awareness of the condition. | Adbel-Rahman El-Zayadi Hanaa M Badran Eman MF Barakat Mohy El-Deen Attia Sherine Shawky Mostafa K Mohamed Osaima Selim Ahmed Saeid | 2005 | World Journal of Gastroenterology2005，11，33： | 5 |
| 8 | Phytochemical studies and anti-ulcerative colitis effect of Moringa oleifera seeds and Egyptian propolis methanol extracts in a rat model显示文摘Objective: To analyze the phytochemical constituents, and to explore potential protective effect of the methanol extract of Moringa oleifera(M. oleifera) seeds and Egyptian propolis, each alone or concurrently administered on acetic acid-induced ulcerative colitis in rats. Methods: Eight groups of 5 rats each were used: normal control group with distilled water, model group, two groups with M. oleifera seeds(100 and 200 mg/kg), two groups with propolis(50 and 100 mg/kg), one group with concurrent administration of both, and one group with prednisolone(reference drug). Macro-and microscopic picture, ulcer index and lesion scores, oxidative markers, inflammatory mediators, in vitro activity of the inflammatory enzymes and 1, 1-diphenyl-2-picrylhydrazyl free radicals scavenging activity were evaluated. The phytochemical constituents of both extracts were explored by GC-MS analysis. Results: Both treatments modulated the macro-and microscopic picture, decreased the ulcerative index, lesion score, oxidative markers and inflammatory mediators, and inhibited the COX-1 and COX-2 enzymes. Propolis appeared to be powerful free radicals scavenger. A powerful synergistic effect of both treatments in modulating the course of the disease was reported. GCMS analysis of methanol extract of M. oleifera seeds and propolis revealed the presence of 50 and 34 compounds, respectively. Conclusions: M. oleifera seeds and propolis methanol extracts have modulated the course of acetic acid-induced ulcerative colitis. Moreover, both treatments induce a good synergistic effect against the disease. Isolation of the active constituents is recommended. | Attia H.Atta Samar M.Mouneir Soad M.Nasr Doaa Sedky Amany M.Mohamed Shimaa A.Atta Hassan Mohamed Desouky | 2019 | Asian Pacific Journal of Tropical Biomedicine2019，9，3： | 4 |
| 9 | Impact of referral pattern and timing of repair on surgical outcome after reconstruction of post-cholecystectomy bile duct injury:A multicenter study显示文摘Background:Bile duct injury(BDI)after cholecystectomy remains a significant surgical challenge.No guideline exists to guide the timing of repair,while few studies compare early versus late repair BDI.This study aimed to analyze the outcomes in patients undergoing immediate,intermediate,and delayed repair of BDI.Methods:We retrospectively analyzed 412 patients with BDI from March 2015 to January 2020.The patients were divided into three groups based on the time of BDI reconstruction.Group 1 underwent an immediate reconstruction(within the first 72 hours post-cholecystectomy,n=156);group 2 underwent an intermediate reconstruction(from 4 days to 6 weeks post-cholecystectomy,n=75),and group 3 underwent delayed reconstruction(after 6 weeks post-cholecystectomy,n=181).Results:Patients in group 2 had significantly more early complications including anastomotic leakage and intra-abdominal collection and late complications including anastomotic stricture and secondary liver cirrhosis compared with groups 1 and 3.Favorable outcome was observed in 111(71.2%)patients in group 1,31(41.3%)patients in group 2,and 157(86.7%)patients in group 3(P=0.0001).Multivariate analysis identified that complete ligation of the bile duct,level E1 BDI and the use of external stent were independent factors of favorable outcome in group 1,the use of external stent was an independent factor of favorable outcome in group 2,and level E4 BDI was an independent factor of unfavorable outcome in group 3.Transected BDI and level E4 BDI were independent factors of unfavorable outcome.Conclusions:Favorable outcomes were more frequently observed in the immediate and delayed reconstruction of post-cholecystectomy BDI.Complete ligation of the bile duct,level E1 BDI and the use of external stent were independent factors of a favorable outcome. | Ayman El Nakeeb Ahmad Sultan Helmy Ezzat Mohamed Attia Mohamed Abd ElWahab Taha Kayed Ayman Hassanen Ahmad AlMalki Ahmed Alqarni Mohammed M Mohammed | 2021 | Hepatobiliary & Pancreatic Diseases International2021，20，1： | 4 |
| 10 | Prevalence and virological profiles of hepatitis B infection in human immunodeficiency virus patients显示文摘AIM: To determine the prevalence of hepatitis B virus (HBV) in adult human immunodeficiency virus (HIV) patients with CD4+ T-cell count less than 500/mm 3 and without antiretroviral therapy; to describe different HBV-HIV coinfection virological profiles; and to search for factors associated with HBs antigen (HBsAg) presence in these HIV positive patients.METHODS: During four months (June through September 2006), 491 patients were received in four HIV positive monitoring clinical centers in Abidjan. Inclusion criteria: HIV-1 or HIV-1 and 2 positive patients, age ≥ 18 years, CD4+ T-cell count < 500/mL and formal and signed consent of the patient. Realized blood tests included HIV serology, CD4+ T-cell count, quantitative HIV RNA load and HBV serological markers, such as HBsAg and HBc antibody (anti-HBcAb). We performed HBeAg, anti-HBe antibody (anti-HBeAb), anti-HBc IgM and quantitative HBV DNA load in HBsAg positive patients. Anti-HBsAb had been tested in HIV patients with HBsAg negative and anti-HBcAb-positive. HBV DNA was also tested in 188 anti-HBcAb positive patients with HBsAg negative status and without anti-HBsAb. Univariate analysis (Pearsonχ 2 test or Fischer exact test) and multivariate analysis (backward step-wise selection logistic regression) were performed as statistical analysis. RESULTS: Mean age of 491 patients was 36 ± 8.68 years and 73.3% were female. Type-1 HIV was found in 97% and dual-type HIV (type 1 plus type 2) in 3%. World Health Organization (WHO) clinical stage was 1, 2, 3 and 4 respectively in 61 (12.4%), 233 (47.5%), 172 (35%) and 25 patients (5.1%). Median CD4+ T-cell count was 341/mm 3 (interquartile range: 221-470). One hundred and twelve patients had less than 200 CD4+ T-cell/mm 3 . Plasma HIV-1 RNA load was elevated (≥ 5 log 10 copies/mL) in 221 patients (45%). HBsAg and anti-HBcAb prevalence was respectively 13.4% and 72.9%. Of the 66 HBsAg positive patients, 22 were inactive HBV carriers (33.3%), 21 had HBeAg positive hepatitis (31.8%) and 20 had HBeAg negative hepatitis (30.3%). HBeAg and anti-HBeAb were indeterminate in 3 of them. Occult B infection prevalence (HBsAg negative, anti-HBcAb positive, anti-HBsAb negative and detectable HBV DNA) was 21.3%. Three parameters were significantly associated with the presence of HBsAg: male [odds ratio (OR): 2.2;P = 0.005; 95% confidence interval (CI): 1.3-3.8]; WHO stage 4 (OR: 3.2;P = 0.01;95% CI: 1.3-7.9); and aspartate aminotransferase (AST) level higher than the standard (OR: 1.9;P = 0.04; 95% CI: 1.02-3.8). CONCLUSION: HBV infection prevalence is high in HIV-positive patients. HBeAg positive chronic hepatitis and occult HBV infection are more frequent in HIVpositive patients than in HIV negative ones. Parameters associated with HBsAg positivity were male gender, AIDS status and increased AST level. | Koffi Alain Attia Serge Eholié Eugène Messou Christine Danel Sandrine Polneau Henri Chenal Thomas Toni Myreille Mbamy Catherine Seyler Naomi Wakasugi Thérèse N'dri-Yoman Xavier Anglaret | 2012 | World Journal of Hepatology2012，4，7： | 4 |
| 11 | Sperm quality improvement after date seed oil in Vitro supplementation in spontaneous and induced oxidative stress显示文摘在有日期种子油(DSO ) 的补充能保护的 vitro,对氢过氧化物(H2O2 ) 的精子调停了损坏和罐头改进精子功能,可能由于抗氧化剂性质。我们在在精子在调停 H2O2 的氧化损坏以后在 vitro 估计的人的精子活动性,精子生存能力,反应 acrosome 和类脂化合物 peroxidation 上测试了 DSO 的抗氧化剂效果。十六个病人(吝啬的年龄:35 年;变化:25 鈥 ? 5 年) 在 12 鈥 ? 以后为精液分析参考了斯法克斯的药教师的组织学鈥揈m 藓苔学实验室 4 月没有概念的性交被选择。在 spermiogram 以后,由二接口的不连续的基石精选坡度的精子选择被表现,并且选择精子在四试验性的试金被使用:控制;有 100 m H2O2 的孵化;有 0.1% DSO 的孵化;并且有 0.1% DSO 和 100 m H2O2 的合作孵化。活动性和生存能力用世界健康组织标准被决定。Acrosome 反应和类脂化合物 peroxidation 被分别地与荧光黄 isothiocyanate-Pisum sativum 和 malondialdehyde 的 spectrophotometric 测量染色估计。结果证明有 H2O2 的孵化独自在类脂化合物 peroxidation 导致了重要增加(57.83% , P < 0.05 ) 在精子活动性与重要减少联系了,精子生存能力(在 30 min 和 24 h 以后) 并且反应 acrosome 的百分比(P < 0.05 ) 。日期种子油在孵化的 24 h 以后改进了精子活动性(P < 0.05 ) 并且对活动性,生存能力, acrosome 反应和类脂化合物上的 H2O2 的有害效果的保护的精子 peroxidation。我们断定有 DSO 的补充可以对男不孕在抗氧化剂保护有功能。 | Ben A. Fatma Chakroun F. Nozha Dammak Ines Attia Hamadi Hentati Basma Ammar K. Leila | 2009 | Asian Journal of Andrology2009，11，3： | 4 |
| 12 | 有序介孔磷酸钛锂离子电池正极材料制备及电化学性能显示文摘选用合适模板剂由溶胶凝胶法合成高度有序介孔结构的磷酸钛正极材料.研究煅烧温度对材料孔结构及材料的电化学性能的影响,合成样品的结构形貌和比表面分别用XRD、BET、TEM及元素分析仪表征.充放电测试结果表明,该介孔结构正极材料表现出优越的电化学性能,以150 mA/g充放电,首次放电容量高达94 mAh/g,而不含模板剂无孔结构的材料放电容量仅37 mAh/g. | 王琼 Adel Attia 施志聪 杨勇 | 2008 | 电化学2008，14，1： | 4 |
| 13 | Dietary fibre and fibre-rich by-products of food processing: Characterisation, technological functionality and commercial applications: A review显示文摘 | Mohamed Elleuch Dorothea Bedigian Olivier Roiseux Souhail Besbes Christophe Blecker Hamadi Attia | 2010 | Food Chemistry2010，，2： | 2 |
| 14 | Systematic review and meta‐analysis of safety of laparoscopic versus open appendicectomy for suspected appendicitis in pregnancy显示文摘 | C. Wilasrusmee B. Sukrat M. McEvoy J. Attia A. Thakkinstian | 2012 | Br J Surg2012，，11： | 2 |
| 15 | Seasonal Variation in Stroke in the Hunter Region, Australia: A 5-Year Hospital-Based Study, 1995-2000显示文摘 | Yang Wang Christopher R. Levi John R. Attia Catherine A. D’Este Neil Spratt Janet Fisher | 2003 | Stroke: Journal of the American Heart Association2003，，5： | 2 |
| 16 | All-epiphyseal versus trans-epiphyseal screw fixation for tillaux fractures:Does it matter?显示文摘BACKGROUND Tillaux fractures occur primarily in adolescents due to the pattern of physeal closure and are classified as Salter-Harris type III physeal fractures.Operative management with screw fixation is recommended for more than 2 mm of displacement or more than 1 mm of translation.However,the efficacy and complications of trans-physeal vs all-physeal screw fixation have not been investigated extensively.AIM To compare the clinical and functional outcomes of trans-physeal(oblique)and all-epiphyseal(parallel)screw fixation in management of Tillaux fractures among pediatric patients.METHODS This was an ethics board approved retrospective review of pediatric patients who presented to our tertiary children’s care facility with Tillaux fractures.We included patients who had surgical fixation of a Tillaux fracture over a 10 year period.Data analysis included demographics,mode of injury,management protocols,and functional outcomes.The patients were divided into group 1(oblique fixation)and group 2(parallel fixation).Baseline patient characteristics and functional outcomes were compared between groups.Statistical tests to evaluate differences included Fisher’s Exact or Chi-squared and independent samples t or Mann Whitney tests for categorical and continuous variables,respectively.RESULTS A total of 42 patients(28 females and 14 males)were included.There were no significant differences in body mass index,sex,age,or time to surgery between the groups[IK2].Sports injuries accounted for 61.9%of the cases,particularly non-contact(57.1%)and skating(28.6%)injuries.Computed Tomography(CT)scan was ordered for 28 patients(66.7%),leading to diagnosis confirmation in 17 patients and change in management plan in 11 patients.[GRC3]Groups 1 and 2 consisted of 17 and 25 patients,respectively.For mid to long-term functional outcomes,there were 14 and 10 patients in groups 1 and 2,respectively.Statistical analysis revealed no significant differences in the functional outcomes,pain scores,or satisfaction between groups.No infections,non-unions,physeal arrest,or post-operative ankle deformities were reported.Two(4.8%)patients had difficulty returning to sports post-surgery due to pain.One was a dancer,and the other patient had pain while running,which led to hardware removal.Both patients had parallel fixation.Hardware removal for groups 1 and 2 were 4(23.5%)and 5(20.0%)patients,respectively.The reasons for removal was pain in 2 patients,and parental preference in the remaining.CONCLUSION This is the largest reported series of pediatric patients with Tillaux fractures comparing functional outcomes of different methods of screw fixation orientation to the physis,which showed no difference regarding functional outcomes. | Brett Heldt Isaiah Roepe Raymond Guo Elsayed Attia Ifeoma Inneh Vinitha Shenava Indranil Kushare | 2022 | World Journal of Orthopedics2022，13，2： | 2 |
| 17 | Date flesh: Chemical composition and characteristics of the dietary fibre显示文摘 | Mohamed Elleuch Souhail Besbes Olivier Roiseux Christophe Blecker Claude Deroanne Nour-Eddine Drira Hamadi Attia | 2008 | Food Chemistry2008，，3： | 2 |
| 18 | Antidiarrhoeal activity of some Egyptian medicinal plant extracts显示文摘 | Attia H Atta Samar M Mouneir | 2004 | Journal of Ethnopharmacology2004，，2： | 2 |
| 19 | The angiotensin Ⅱ receptor antagonist, losartan, inhibits LDL lipid peroxidation and atherosclerosis in apolipoprotein E-deficient mice显示文摘 | Attias J Smith J | 1997 | Biochem Biophys Res Commun1997，236，： | 1 |
| 20 | Myocardial performance in asphyxiated full-term infants assessed by Doppler tissue imaging显示文摘 | Matter M Abdel-Hady H Attia G Hafez M Seliem W A1-Arman M | 2010 | Pediatr Cardiol2010，31，5： | 1 |
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