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| 1 | Systematic Identification of the Light-quality Responding Anthocyanin Synthesis-related Transcripts in Petunia Petals显示文摘Previous studies have shown that high light intensity can induce anthocyanin synthesis(AS)in petunia plants.To identifywhich kind of light quality plays a role in inducing such metabolic process,and what transcripts participate in controlling it,we carried out whole-transcriptome sequencing and analysis of petunia petals treated with different light-quality conditions.Among the red and white light treatments,a total of 2205 differentially expressed genes and 15,22,and 20 differentially expressed circRNAs,miRNAs,and lncRNAs,were identified respectively.The AS-related genes,including the structural genes CHSj,F3H,F35H,DFR,and ANS,and the regulatory genes AN4,DPL,PHZ and MYBx were found to be downregulated under red light condition compared with their levels under white light condition.Furthermore,the light photoreceptor Cryptochrome 3(CRY3)and a series of light-dependent genes,such as PIF,HY5,andBBXs,were also determined to respond to the light treatments.The anthocyanin contents in early petunia petals under red light were significantly lower than that under white and blue light.The results of qRT-PCR further confirmed the expression pattern of some AS-related and light-response genes in response to different light quality.Yeast two-hybrid results showed that the key elements in the light signal pathway,HY5 can interact with BBX19,BBX24 and BBX25.And PHZ,the important AS regulator can induce anthocyanin synthesis in response to blue light quality fromtransient expression analysis in petunia petals.These findings presented here not only deepen our understanding of how light quality controls anthocyanin synthesis,but also allow us to explore potential target genes for improving pigment production in petunia flower petals. | Zhenzhu Fu Hongquan Shang Hui Jiang Jie Gao Xiaoyu Dong Huijuan Wang Yanmin Li Limin Wang Jing Zhang Qingyan Shu Yacong Chao Menglan Xu Rui Wang Liangsheng Wang Hechen Zhang | 2020 | Horticultural Plant Journal2020，6，6： | 7 |
| 2 | A new design of automatic vertical drilling tool显示文摘In order to effectively improve penetration rates and enhance wellbore quality for vertical wells,a new Automatic Vertical Drilling Tool(AVDT)based on Eccentric Braced Structure(EBS)is designed.Applying operating principle of rotary steering drilling,AVDT adds offset gravity block automatic induction inclination mechanism.When hole straightening happens,tools take essentric moment to be produced by gravity of offset gravity lock to control the bearing of guide force,so that well straightening is achieved.The normal tool's size of the AVDT is designed as 215.9 mm,other major components'sizes are worked out by the result of theoretical analysis,including the offset angle of EBS.This paper aims to introduce the structure,operating principle,theoretical analysis and describe the key components'parameters setting of the AVDT. | Yanfeng Ma Hongquan Xia Junxiong Fu Peng Yang | 2015 | Petroleum2015，1，3： | 3 |
| 3 | The DNMT1-PAS1-PH20 axis drives breast cancer growth and metastasis显示文摘PH20 is a member of the human hyaluronidase family that degrades hyaluronan in the extracellular matrix and controls tumor progression.Inhibition of DNA methyltransferases(DNMTs)leads to elevated hyaluronan levels;however,whether DNMT inhibitors control PH20 remains unclear.Here,we report that the DNMT1 inhibitor,decitabine,suppresses PH20 expression by activating the long non-coding RNA PHACTR2-AS1(PAS1).PAS1 forms a tripartite complex with the RNA-binding protein vigilin and histone methyltransferase SUV39H1.The interaction between PAS1 and vigilin maintains the stability of PAS1.Meanwhile,PAS1 recruits SUV39H1 to trigger the H3K9 methylation of PH20,resulting in its silencing.Functionally,PAS1 inhibits breast cancer growth and metastasis,at least partially,by suppressing PH20.Combination therapy of decitabine and PAS1-30nt-RNA,which directly binds to SUV39H1,effectively blocked breast cancer growth and metastasis in mice.Taken together,DNMT1,PAS1,and PH20 comprise a regulatory axis to control breast cancer growth and metastasis.These findings reveal that the DNMT1-PAS1-PH20 axis is a potential therapeutic target for breast cancer. | Yenan Fu Xi Zhang Xiao Liu Peng Wang Wenhui Chu Wei Zhao Yunling Wang Guangbiao Zhou Yu Yu Hongquan Zhang | 2022 | Signal Transduction and Targeted Therapy2022，7，4： | 2 |
| 4 | Novel fusiform core-shell-MOF derived in tact metal@carb on composite:An efficient cathode catalyst for aqueous and solid-state Zn-air batteries显示文摘Owing to the varied mechanisms of ORR/OER,exploiting cost-effective bifunctional catalysts with robust ORR/OER activities and excellent performances in Zn-air batteries is still a challenge.In this work,the Co/CoO@NSC bifunctional catalyst is obtained by using Zn-MOF@Co-MOF as self-template.The Co/CoO@NSC composite has interconnected porous architecture with in tact metal@carb on structure,exhibiting superior electrocatalytic activities toward ORR and OER that can be comparable with the Pt/C and RuO_(2) catalysts,respectively.The Co/CoO@NSC-based aqueous Zn-air battery achieves a high specific capacity(759.7 mAh/g)and energy density(990.5 Wh/kg),and ultra-long rechargeable property(more than 400 h/1200 cycles).The Co/CoO@NSC-based solid-state Zn-air battery also delivers an excellent performance with a long cycle life(more than 143 h/858 cycles).Most importantly,the newly synthesized and recharged Co/CoO@NSC-based solid-state Zn-air battery can be used to light up a 2 V LED lamp for more than 28 h,demonstrating the superior practicability as rechargeable power source. | Di Zhou Hongquan Fu Jilan Long Kui Shen Xinglong Gou | 2022 | Journal of Energy Chemistry2022，31，1： | 1 |
| 5 | Microwave-assisted hydrothermal synthesis and temperature sensing application of Er 3+ /Yb 3+ doped NaY(WO 4 ) 2 microstructures显示文摘 | Hui Zheng Baojiu Chen Hongquan Yu Jinsu Zhang Jiashi Sun Xiangping Li Min Sun Bining Tian Shaobo Fu Hua Zhong Bin Dong Ruinian Hua Haiping Xia | 2014 | Journal of Colloid And Interface Science2014，，： | 1 |
| 6 | 3D Printing Technology for Short-continuous Carbon Fiber Synchronous Reinforced Thermoplastic Composites:A Comparison between Towpreg Extrusion and In Situ Impregnation Processes显示文摘Three-dimensional(3D)printing of carbon fiber-reinforced thermoplastic composites(CFRTPs)provides an ef-fective method for manufacturing the CFRTPs parts with complex structures.To increase the mechanical per-formance of these parts,a 3D printing technology for short-continuous carbon fiber synchronous-reinforced thermoplastic composites(S/C-CFRTPs)has been proposed.However,the synchronous reinforcement that ex-isted only at particular positions led to a limited improvement in the mechanical performance of the 3D-printed S/C-CFRTP part,which made it challenging to meet the engineering requirements.To solve this problem,two methods for achieving synchronous reinforcement at all the positions of the 3D-printed S/C-CFRTP part are pro-posed.To determine a suitable printing process for the S/C-CFRTP part,a comprehensive comparison between the two methods was conducted through theoretical analysis and experimental verification,involving the print-ing mechanism,fiber content,impregnation percentage,and mechanical performance.The results indicated that the towpreg extrusion process was suitable for manufacturing the 3D-printed S/C-CFRTP part.Compared with the in situ impregnation process,the towpreg extrusion process led to a fiber content increase of approximately 7%and void rate reduction of approximately 6%,resulting in 19%and 20%increases in the tensile and flexural strengths of the 3D-printed S/C-CFRTPs,respectively.Additionally,an optimized process parameter setting for fabricating an S/C-CFRTP prepreg filament with excellent mechanical performance was proposed.The findings of this study can provide a new approach for further improving the mechanical performance of the 3D-printed advanced composites. | Fuji Wang Gongshuo Wang Hongquan Wang Rao Fu Yajing Lei Jianing He | 2023 | Chinese Journal of Mechanical Engineering(Additive Manufacturing Frontiers)2023，2，3： | 0 |
| 7 | 细胞自噬通过清除SQSTM1/p62调控DNA损伤引起的染色质泛素化显示文摘细胞基因组时刻遭受着来自细胞内和细胞外因素的损伤威胁,目前有研究表明细胞自噬的缺失也会导致基因组损伤积累,并进一步导致相关疾病发生。但对于细胞自噬和DNA损伤应答两者之间的关系仍缺乏足够了解。 | Yanan Wang Nan Zhang Luyao Zhang Ran Li Wan Fu Ke Ma Xue Li Lina Wang Jiadong Wang Hongquan Zhang Wei Gu 朱卫国 赵颖 | 2017 | 科学新闻2017，19，4： | 0 |
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