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| 1 | Developing a donation after cardiac death risk index for adult and pediatric liver transplantation显示文摘AIM To identify objective predictive factors for donor after cardiac death(DCD) graft loss and using those factors, develop a donor recipient stratification risk predictive model that could be used to calculate a DCD risk index(DCD-RI) to help in prospective decision making on organ use.METHODS The model included objective data from a single institute DCD database(2005-2013, n = 261). Univariate survival analysis was followed by adjusted Cox-regressional hazard model. Covariates selected via univariate regression were added to the model via forward selection, significance level P = 0.3. The warm ischemic threshold was clinically set at 30 min. Points were given to each predictor in proportion to their hazard ratio. Using this model, the DCD-RI was calculated. The cohort was stratified to predict graft loss risk and respective graft survival calculated.RESULTS DCD graft survival predictors were primary indication for transplant(P = 0.066), retransplantation(P = 0.176), MELD > 25(P = 0.05), cold ischemia > 10 h(P = 0.292) and donor hepatectomy time > 60 min(P = 0.028).According to the calculated DCD-RI score three risk classes could be defined of low(DCD-RI < 1), standard(DCD-RI 2-4) and high risk(DCD-RI > 5) with a 5 years graft survival of 86%, 78% and 34%, respectively.CONCLUSION The DCD-RI score independently predicted graft loss(P < 0.001) and the DCD-RI class predicted graft survival(P < 0.001). | Shirin Elizabeth Khorsandi Emmanouil Giorgakis Hector Vilca-Melendez John O'Grady Michael Heneghan Varuna Aluvihare Abid Suddle Kosh Agarwal Krishna Menon Andreas Prachalias Parthi Srinivasan Mohamed Rela Wayel Jassem Nigel Heaton | 2017 | World Journal of Transplantation2017，7，3： | 3 |
| 2 | 策略将在肝移植以后减少丙肝病毒复发显示文摘 Hepatitis C virus (HCV) is a major health problem that leads to chronic hepatitis, cirrhosis and hepatocellular carcinoma, being the most frequent indication for liver transplantation in several countries. Unfortunately, HCV re-infects the liver graft almost invariably following reperfusion, with an accelerated history of recurrence, leading to 10%-30% of patients progressing to cirrhosis within 5 years of transplantation. In this sense, some groups have even advocated for not retransplanting this patients, as lower patient and graftoutcomes have been reported. However, the management of HCV recurrence is being optimized and several strategies to reduce post-transplant recurrence could improve outcomes, decrease the rate of re-transplantation and optimize the use of available grafts. Three moments may be the focus of potential actions in order to decrease the impact of viral recurrence: the pretransplant moment, the transplant environment and the post-transplant management. In the pre-transplant setting, it is not well established if reducing the pre transplant viral load affects the risk for HCV progression after transplant. Obviously, antiviral treatment can render the patient HCV RNA negative post transplant but the long-term benefit has not yet been fully established to justify the cost and clinical risk. In the transplant moment, factors as donor age, cold ischemia time, graft steatosis and ischemia/reperfusion injury may lead to a higher and more aggressive viral recurrence. After the transplant, discussion about immunosuppression and the moment to start the treatment (prophylactic, pre-emptive or once-confirmed) together with new antiviral drugs are of interest. This review aims to help clinicians have a global overview of posttransplant HCV recurrence and strategies to reduce its impact on our patients. | Ruben Ciria María Pleguezuelo Shirin Elizabeth Khorsandi Diego Davila Abid Suddle Hector Vilca-Melendez Sebastian Rufian Manuel de la Mata Javier Briceo Pedro López Cillero Nigel Heaton | 2013 | World Journal of Hepatology2013，5，5： | 2 |
| 3 | Entrepreneurship and development: the role of cluster显示文摘 | ROCHA HECTOR O | 2004 | Small Business Economies2004，23，5： | 1 |
| 4 | Rocha, Entrepreneurship and Development: The Role of Clusters 显示文摘 | Hector O | 2004 | Small Business Economics2004，23，8： | 1 |
| 5 | DIVERSE CARDIOPROTECTIVE SIGNALING MECHANISMS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ LIGANDS, 15-DEOXY-Δ12,14-PROSTAGLANDIN J2 AND CIGLITAZONE, IN REPERFUSION INJURY: ROLE OF NUCLEAR FACTOR-κB, HEAT SHOCK FACTOR 1, AND AKT显示文摘 | Basilia Zingarelli Paul W. Hake Prajakta Mangeshkar Michael O'Connor Timothy J. Burroughs Giovanna Piraino Alvin Denenberg Hector R. Wong | 2007 | Shock2007，，5： | 1 |
| 6 | Capture of hair geometry from multiple images显示文摘 | Sylvain Paris Hector M. Brice?o Fran?ois X. Sillion | 2004 | ACM Transactions on Graphics (TOG)2004，，3： | 1 |
| 7 | Low-diameter mesocaval shunt 显示文摘 | Miguel AM Hector O | 2007 | AtlasUpper Gastrointest HPB Surg2007，9，6： | 1 |
| 8 | Optimizing chemical conditioning for odour removal of undigested sewage sludge in drying processes 显示文摘 | Vega E M Hector G O | 2015 | Journal Of Environmental Management2015，3，150： | 1 |
| 9 | Optimizing chemical condition- ing for odour removal of undigested sewage sludge in dr- ying processes 显示文摘 | Vega E M Hector G O | 2015 | J Environ Manage2015，150，3： | 1 |
| 10 | Temporal trends in weight and current weight-related behaviour of Australian Aboriginal school- aged children显示文摘 | Hardy LL O'Hara BJ Hector D | 2014 | Med J Aust2014，200，1： | 1 |
| 11 | Two - stage coalescence in double emulsions 显示文摘 | HECTOR G O LAURA I B ARAUZLARA J | 2003 | Langmuir2003，19，： | 1 |
| 12 | Studies on ACTH action in perfused bovine ad- renals:aspects of progesterone as an intermediary in cortieosteroi- dogenesis 显示文摘 | Stone D Hector O | 1955 | Arch Biochem Biophys1955，54，： | 1 |
| 13 | Lung injury after hemorrhage is age dependent: Role of peroxisome proliferator-activated receptor γ显示文摘 | Basilia Zingarelli Paul W. Hake Michael O’Connor Timothy J. Burroughs Hector R. Wong Joseph S. Solomkin Alex B. Lentsch | 2009 | Critical Care Medicine2009，，6： | 1 |
| 14 | Effect of temperature on the inhibition kinetics of phenol biodegradation by Psudomonas putida Q5显示文摘 | Kira A O Hector M B Campbell W R | 2000 | Biotechnol Bioeng2000，70，： | 1 |
| 15 | mos s amb ic us (Peters) while adapting toincreasing salinity显示文摘 | Alfredo M-H Hector S-L Blood gasometric trends in hybrid-red tilapia Oreochromis nilotic us (Linnaeus)×O | | 0，，： | 1 |
| 16 | Human germinal center B cells express the apoptosis-inducing genes Fas,c-myc,p53 and Bax but not the survival gene bcl-2显示文摘 | Cristiane G Bouteiller O | 1996 | J Exp Med1996，183，3： | 1 |
| 17 | Adsorption behavior of statherin and a statherin peptide onto hydroxyapatite and silica surfaces by in situ ellipsometry 显示文摘 | Santos O Kosoric J Hector MP | 2008 | J Colloid Interface Sci2008，318，2： | 1 |
| 18 | Productivity is a poor predictor of plant species richness显示文摘 | Adler PB Seabloom EW Borer ET Hillebrand H Hautier Y Hector A Harpole WS O'Halloran LR Grace JB Anderson TM Bakker JD Biederman LA Brown CS Buckley YM Calabrese LB Chu C J Cleland EE Collins SL Cottingham KL Crawley M J Damschen EI Davies KF DeCrappeo NM | | 0，，： | 1 |
| 19 | Identification of Leu- conostoc strains isolated from kimchi using carbon-source utilization patterns 显示文摘 | Lee J S Chun C O Hector M | 1997 | Journal of Microbiology1997，35，1： | 1 |
| 20 | No consistent effect of plant diversity on productivity显示文摘 | Huston M A Aarssen L W Austin M P Cade B S Fridley J D Garnier E Grime J P Hodgson J Lauenroth W K Thompson K Vandermeer J H Wardle D A Hector A Schmid B Beierkuhnlein C Caldeira M C Diemer M Dimitrakopoulos P G Finn J A Freitas H Giller P S Good J Harris R Hogberg P Huss-Danell K Joshi J Jumpponen A Korner C Leadley P W Loreau M Minns A Mulde C P H O'Donovan G Otway S J Pereira J S Prinz A Read D J Scherer-Lorenzen M Schulze E D Siamanrziouras A S D Spehn E Terry A C Troumbis A Y Woodward F I Yaehi S Lawton J H | 2000 | Science2000，289，： | 1 |
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