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| 1 | Waist Circumference Distribution of Chinese School-age Children and Adolescents显示文摘Background Waist circumference(WC),a proxy measure of central body fat,is a better predictor than overall body fat for cardiovascular risk factors in both adults and children.WC cutoffs have been established in many countries,but the national WC reference has not been developed in China.Objective To study the distribution of WC in a representative group of Chinese children for establishing Chinese WC cutoff points.Methods Cross-sectional data obtained from 15 mainland provinces and Hong Kong were collected.There were 160 225 children and adolescents aged 7-18 years old in total.The subjects were divided into five regional groups namely costal city,other city,north rural,south rural,and Hong Kong,for analyzing the distribution of WC.Results A large variation in WC distribution was found among the five groups for both sexes.Coastal city group had the highest P85 WC values consistently from the early school ages to 18-year-old compared with other groups.In contrast,south rural group had P85 values consistently lagged behind not only the city groups but also the north rural group.Hong Kong group had a high P85 WC at early ages,but because of the smaller increments of WC during adolescence,the P85 curve was gradually exceeded by the north rural groups.Catch-up trend was found in the two rural groups since the peak of puberty.These disparities were caused by not only socioeconomic and urban-rural factors but also north-south differences.Because of the regional variation of WC,a 'gradient' prevalence of central obesity was prospected among these groups.Comparisons of WC distributions between the Chinese and the U.S.A or Netherlands demonstrated the necessary of setting up China's own WC cutoffs.Sex and age-specific percentiles were obtained and smoothed by using LMS method.Conclusion The data obtained from this study could be used to develop national WC cutoff points for Chinese children and adolescents. | CHENG-YE JI RITA YT SUNG GUAN-SHENG MA JUN MA ZHONG-HU HE TIAN-JIAO CHEN | 2010 | Biomedical and Environmental Sciences2010，23，1： | 22 |
| 2 | 体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。 | 刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B | 2020 | 中华高血压杂志2020，28，3： | 22 |
| 3 | Long-term follow-up of a Community Assignment,one-time endoscopic screening study of esophageal cancer in China显示文摘 | Wei WQ Chen ZF He YT | 2015 | J Clin Oncol2015，33，17： | 1 |
| 4 | Trends in incidence of e sophageal and gastric cardia cancer in high risk areas in China显示文摘 | He YT Hou J Chen ZF | 2008 | Eur J Cancer Prey2008，17，2： | 1 |
| 5 | Trends in incidence of the esophageal and gastric cardia cancer in high risk areas in China 显示文摘 | He YT Hou J Chen ZF | 2008 | Euro J Cancer Prey2008，17，2： | 1 |
| 6 | Relationship between platelet counts and cartilage erosion in 436 cases of rheumatoid arthritis 显示文摘 | Zha QL He YT Lu YX | 2006 | Clin Chem Acta2006，371，12： | 1 |
| 7 | Trends in incidence of the esophageal and gastric cardia cancer in high-risk areas,China显示文摘 | He YT Hou J Chen ZF | 2008 | Eur J Cancer Prev2008，17，2： | 1 |
| 8 | Effects of intratracheal administration of nuclear factor-kappaB decoy oligodeoxynucleotides on long-term cigarette smoke-induced lung inflammation and pathology in mice显示文摘 | Li YT He B Wang YZ | 2009 | Respir Res2009，25，10： | 1 |
| 9 | Traditional Chinese medicine versus western medicine as used in China in themanagement of rheumatoid arthritis:a randomized,single-blind,24-week study显示文摘 | He YT Ou AH Yang XB | 2014 | Rheumatol Int2014，34，12： | 1 |
| 10 | A traditional Chinese medicine formulation consisting of Rhizoma Corydalis and Rhizoma Curcumae exerts synergistic anti-tumor activity显示文摘 | Gao JL He TC Li YB Wang YT | | 0，，05： | 1 |
| 11 | Biogenic Mn oxides for effective adsorption of Cd from aquatic environment 显示文摘 | Meng YT Zheng YM Zhang LM He JZ | 2009 | Environ Poll2009，157，89： | 1 |
| 12 | Apoptosis of interstitial cells of Cajal, smooth muscle cells, and enteric neurons induced by intestinal ischemia and reperfusion injury in adult guinea pigs 显示文摘 | Mei F Guo S He YT | 2009 | Virehows Arch2009，454，4： | 1 |
| 13 | Trends in incidence of esophageal and gastric cardia cancer in high-risk areas in China显示文摘 | He YT Hou J Chen ZF | 2008 | Eur J Cancer Prev2008，17，2： | 1 |
| 14 | Mechanistic Analysis of Trehalose Synthase from Mycobacterium smegmatis 显示文摘 | ZHANG R PAN YT HE S | 2011 | Journal of Biological Chem- istry2011，286，35： | 1 |
| 15 | An engineered complement receptor 1 composed of two functional domains can protect against immune-mediated hemolysis显示文摘 | Yang YT He L Tan B | 2009 | Protein Exp Purif2009，66，： | 1 |
| 16 | Decrease in the esophageal cancer incidence rate in mountainous but not level parts of Cixian Coun- ty, China, over 29 years显示文摘 | He YT Hou J Chen ZF | 2005 | Asian PacJ Cancer Prey2005，6，4： | 1 |
| 17 | Trends in incidence of esophageal and gastric cardia cancer in high-risk areas in China显示文摘 | He YT Hou J Chen ZF | 2008 | Eur J Cancer Prev2008，17，2： | 1 |
| 18 | Prevention of amyloid fibril formation of amyloidogenic chicken cystatin by site-specific glycosylation in yeast 显示文摘 | He JW Song YT Nobuhiro U | 2006 | Protein Sci2006，15，2： | 1 |
| 19 | Effect of Epsl gene deletion in Saccharomyces cerevisiae on the secretion of foreign proteins which have disulfide bridges显示文摘 | He JW Sakamoto T Song YT | 2005 | FEBS Letters2005，579，11： | 1 |
| 20 | Glutathione-S-transferase enhances proliferation-migration and protects against shikonin-induced cell death in breast cancer cells显示文摘 | He S Liao TT Chen YT | 2011 | Kaohsiung J Med Sci2011，27，11： | 1 |
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