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| 1 | Carbon Dioxide Captured from Flue Gas by Modified Ca-based Sorbents in Fixed-bed Reactor at High Temperature显示文摘Four kinds of Ca-based sorbents were prepared by calcination and hydration reactions using different precursors: calcium hydroxide, calcium carbonate, calcium acetate monohydrate and calcium oxide. The CO2 absorption capacity of those sorbents was investigated in a fixed-bed reactor in the temperature range of 350-650℃. It was found that all of those sorbents showed higher capacity for CO2 absorption when the operating temperature higher than 450℃. The CaAc2-CaO sorbent showed the highest CO2 absorption capacity of 299mg·g-1. The morphology of those sorbents was examined by scanning electron microscope (SEM), and the changes of composition before and after carbonation were also determined by X-ray diffraction (XRD). Results indicated that those sorbents have the similar chemical compositions and crystalline phases before carbonation reaction [mainly Ca(OH)2], and CaCO3 is the main component after carbonation reaction. The SEM morphology shows clearly that the sorbent pores were filled with reaction products after carbonation reaction, and became much denser than before. The N2 adsorption-desorption isotherms indicated that the CaAc2-CaO and CaCO3-CaO sorbents have higher specific surface area, larger pore volume and appropriate pore size distribution than that of CaO-CaO and Ca(OH)2-CaO. | YANG Lei YU Hongbing WANG Shengqiang WANG Haowen ZHOU Qibin | 2013 | Chinese Journal of Chemical Engineering2013，21，2： | 8 |
| 2 | AI Enabled Wireless Communications with Real Channel Measurements:Channel Feedback显示文摘Artificial intelligence(AI)has shown great potential in wireless communications.AI-empowered communication algorithms have beaten many traditional algorithms through simulations.However,the existing works just use the simulated datasets to train and test the algorithms,which can not represent the power of AI in practical communication systems.Therefore,Peng Cheng Laboratory holds an AI competition,National Artificial Intelligence Competition(NAIC):AI+wireless communications,in which one of the topics is AI-empowered channel feedback system design using practical measurements.In this paper,we give a baseline neural network design,QuanCsiNet,for this competition,and the details of the channel measurements.QuanCsiNet shows excellent performance on channel feedback and the complexity of the neural networks is also given. | Jiajia Guo Xiangyi Li Muhan Chen Peiwen Jiang Tingting Yang Weiming Duan Haowen Wang Shi Jin Quan Yu | 2020 | Journal of Communications and Information Networks2020，5，3： | 2 |
| 3 | Efficient production of chemicals from microorganism by metabolic engineering and synthetic biology显示文摘The use of traditional chemical catalysis to produce chemicals has a series of drawbacks,such as high dependence on fossil resources,high energy consumption,and environmental pollution.With the development of synthetic biology and metabolic engineering,the use of renewable biomass raw materials for chemicals synthesis by constructing efficient microbial cell factories is a green way to replace traditional chemical catalysis and traditional microbial fermentation.This review mainly summarizes several types of bulk chemicals and high value-added chemicals using metabolic engineering and synthetic biology strategies to achieve efficient microbial production.In addition,this review also summarizes several strategies for effectively regulating microbial cell metabolism.These strategies can achieve the coupling balance of material and energy by regulating intracellular material metabolism or energy metabolism,and promote the efficient production of target chemicals by microorganisms. | Yang Zhang Jing Yu Yilu Wu Mingda Li Yuxuan Zhao Haowen Zhu Changjing Chen Meng Wang Biqiang Chen Tianwei Tan | 2021 | Chinese Journal of Chemical Engineering2021，34，2： | 2 |
| 4 | Deformation induced anisotropic responses of Ti–6Al–4V alloy Part II: A strain rate and temperature dependent anisotropic yield criterion显示文摘 | Akhtar S. Khan Shaojuan Yu Haowen Liu | 2012 | International Journal of Plasticity2012，，： | 1 |
| 5 | Association between Metabolic Dysfunction-associated Fatty Liver Disease and Cognitive Impairment显示文摘Background and Aims:Metabolic dysfunction-associated fatty liver disease(MAFLD)is a newly proposed term based on modified criteria.Although nonalcoholic fatty liver disease(NAFLD)has been well-documented as a multisystem dis-ease,research on the correlation of MAFLD and extra-hepatic diseases is limited.This study aimed to clarify the association of MAFLD,as well as NAFLD status with cognitive function.Methods:A total of 5,662 participants 20-59 years of age who underwent cognitive tests and liver ultrasonography in the Third National Health and Nutrition Examination Survey were included in the analysis.Cognitive function was evalu-ated using three computer-administered tests,the serial dig-it learning test(SDLT),the simple reaction time test(SRTT)and the symbol digit substitution test(SDST).Results:Par-ticipants with MAFLD had significantly poorer performance on the SRTT[odds ratio(OR)1.47,95%confidence interval(CI):1.14-1.89)].MAFLD with moderate-severe liver stea-tosis was associated with higher risks of scoring low in the SDLT(OR 1.37,95%CI:1.04-1.82)and SRTT(OR 1.55,95%CI:1.19-2.02).NAFLD combined with metabolic dys-function,instead of NAFLD without metabolic disorders,was associated an increased risk of a low SRTT score(OR 1.44,95%CI:1.10-1.82).MAFLD patients had a high probability of fibrosis,prediabetes,and diabetes and were also signifi-cantly associated with increased risks based on the SDST or SRTT score.Conclusions:MAFLD was significantly associ-ated with increased risk of cognitive impairment,especially among MAFLD patients with a high degree of liver fibrosis,moderate-severe steatosis,or hyperglycemia. | Qiang Yu Ruixin He Haowen Jiang Ji Wu Zhifeng Xi Kang He Yongbo Liu Tao Zhou Mingxuan Feng Ping Wan Hexin Yan Qiang Xia | 2022 | Journal of Clinical and Translational Hepatology2022，10，6： | 1 |
| 6 | Exploration and Application of Ubiquitous Mapping in Engineering Practice Courses in the Intelligence Age显示文摘In the current era of digital surveying and mapping to intelligent surveying and mapping,ubiquitous surveying and mapping has brought many opportunities and challenges to college engineering course teaching.With the development of ubiquitous surveying and mapping,college engineering practice courses urgently need to respond to ubiquitous surveying and mapping.The research aims to integrate the development of ubiquitous surveying and mapping into the teaching of engineering practice courses in colleges,including promoting Android,Brower/Server(B/S),and Client/Server(C/S)to build a platform for practice courses.This also incorporates real development cases in measurement data processing such as gravity field refinement.In this way,the teaching level of engineering practice courses in colleges can be improved,and new ideas can be put forward for cultivating surveying and mapping talents in the new era in colleges.Finally,it can also provide new ideas for the organization of surveying and mapping practice courses under the background of the pandemic. | Wei LI Xukang XIE Haowen YAN Van Der Meijde MARK Lulu LIU Qianwen WANG Pengcheng GAO Hongyuan YU | 2022 | Journal of Geodesy and Geoinformation Science2022，5，3： | 1 |
| 7 | Metalens-based stereoscopic microscope显示文摘Stereoscopic microscopy is a promising technology to obtain three-dimensional microscopic images.Such microscopes are based on the parallax effect,and as such require two lenses to focus at two different points.Geometrical constraints,however,restrict their numerical apertures to about 0.2,thus limiting the system’s resolution.Higher numerical apertures(.35)can be achieved with designs using only one bulk lens,but such systems are0 times more costly than the conventional ones.Thus,there is a pressing need for alternative solutions to improve the resolution of stereoscopic systems.Here,we show that high-resolution and low-cost stereoscopic systems can be obtained using birefringent single-layer metalenses.We design and fabricate a birefringent metalens operating at 532 nm with a numerical aperture as high as 0.4.The metalens is then used to demonstrate high-resolution stereoscopic imaging of biological samples.The microscopic images are further displayed and perceived vividly in an autostereoscopic display.Our demonstration paves the way to a new strategy to achieve high-resolution and low-cost stereoscopic microscopes. | YONG LONG JIANCHAO ZHANG ZHIHAO LIU WEIBIN FENG SONGMING GUO QIAN SUN QINFEI WU XIANGYANG YU JIANYING ZHOU EMILIANO RMARTINS HAOWEN LIANG JUNTAO LI | 2022 | Photonics Research2022，10，6： | 1 |
| 8 | Highly reconfigurable silicon integrated microwave photonic filter towards next-generation wireless communication显示文摘Integrated microwave photonic filters(IMPFs)are capable of offering unparalleled performances in terms of superb spectral fineness,broadband,and more importantly,the reconfigurability,which encounter the trend of the next-generation wireless communication.However,to achieve high reconfigurability,previous works should adopt complicated system structures and modulation formats,which put great pressure on power consumption and controlment,and,therefore,impede the massive deployment of IMPF.Here,we propose a streamlined architecture for a wideband and highly reconfigurable IMPF on the silicon photonics platform.For various practical filter responses,to avoid complex auxiliary devices and bias drift problems,a phase-modulated flexible sideband cancellation method is employed based on the intensity-consistent single-stage-adjustable cascadedmicroring(ICSSA-CM).The IMPF exhibits an operation band extending to millimeter-wave(≥30 GHz),and other extraordinary performances including high spectral resolution of 220 MHz and large rejection ratio of 60 d B are obtained.Moreover,Gb/s-level RF wireless communications are demonstrated for the first time towards real-world scenarios.The proposed IMPF provides broadband flexible spectrum control capabilities,showing great potential in the next-generation wireless communication. | ZIHAN TAO YUANSHENG TAO MING JIN JUN QIN RUIXUAN CHEN BITAO SHEN YICHEN WU HAOWEN SHU SHAOHUA YU XINGJUN WANG | 2023 | Photonics Research2023，11，5： | 0 |
| 9 | Submilliwatt, widely tunable coherent microcomb generation with feedback-free operation显示文摘Microcombs are revolutionizing optoelectronics by providing parallel, mutually coherent wavelengthchannels for time-frequency metrology and information processing. To implement this essential function inintegrated photonic systems, it is desirable to drive microcombs directly with an on-chip laser in a simpleand flexible way. However, two major difficulties have prevented this goal: (1) generating mode-lockedcomb states usually requires a significant amount of pump power and (2) the requirement to align laser andresonator frequency significantly complicates operation and limits the tunability of the comb lines. Here, weaddress these problems by using microresonators on an AlGaAs on-insulator platform to generate dark-pulsemicrocombs. This highly nonlinear platform dramatically relaxes fabrication requirements and leads to arecord-low pump power of <1 mW for coherent comb generation. Dark-pulse microcombs facilitated bythermally controlled avoided mode crossings are accessed by direct distributed feedback laser pumping.Without any feedback or control circuitries, the comb shows good coherence and stability. With around150 mW on-chip power, this approach also leads to an unprecedentedly wide tuning range of over one freespectral range (97.5 GHz). Our work provides a route to realize power-efficient, simple, and reconfigurablemicrocombs that can be seamlessly integrated with a wide range of photonic systems. | Haowen Shu Lin Chang Chenghao Lao Bitao Shen Weiqiang Xie Xuguang Zhang Ming Jin Yuansheng Tao Ruixuan Chen Zihan Tao Huajin Chang Shaohua Yu Qifan Yang Xingjun Wang John E.Bowers | 2023 | Advanced Photonics2023，5，3： | 0 |
| 10 | miR-182通过调节骨骼肌的葡萄糖利用调控代谢稳态显示文摘阐明骨骼肌肌纤维分型以及代谢转换的调控机制将有助于深入了解生理和疾病条件下的能量代附。 | Duo Zhang Yan Li Xuan Yao Hui Wang Lei Zhao Haowen Jiang Xiaohan Yao Shengjie Zhang Cheng Ye Wei Liu Hongchao Cao Shuxian Yu Yucheng Wang Qiong Li Jingjing Jiang Yi Liu Ling Zhang Yun Liu Naoharu Iwai Hui Wang Jingya Li Jia Li Xihua Li 金子兵 应浩 | 2017 | 科学新闻2017，19，4： | 0 |
| 11 | Microarray screening of differentially expressed genes in DCX transfected U87 cells before and after irradiation显示文摘Radiation therapy plays a critical role in the treatment of neurogliocytoma and it is known that doublecortin (DCX)-transfected U87 cells can inhibit tumor cell growth. Microarray analysis to screen for differentially expressed genes in DCX-transfected U87 cells before and after radiation uncovered DCX-related genes, the functions of DCX, and downstream genes in radiation therapy of neurogliocytoma. Stably transfected U87 cells were constructed (DCX-U87) and the differentially expressed genes were screened by microarray analysis to compare U87 cells with DCX-U87 cells in both non-irradiated and irradiated conditions. Cells were irradiated using 60Co γ-ray at a dose rate of 1.0 Gy/min. Mean values were subject to paired comparison analysis and genes with a p-value of less than 0.05 were analyzed. Differentially expressed genes can correlate with radiation sensitivity and DCX transfection. DCX and SPN proteins in DCX-U87 cells were detected by two groups of 0 and 10 Gy, but not the U87 cells, and their expression levels were higher in the 10 Gy group than in the 0 Gy group. The differential gene expression in DCX-U87 cells before and after radiation is helpful for future investigations into the mechanisms of radiation therapy in neurogliocytoma cells. | FENG Shuang WANG Jie JIANG Xin XU Yuanyuan ZHANG Haowen Cao Jianping YU Jiahua LIU Fenju | 2012 | Nuclear Science and Techniques2012，23，2： | 0 |
| 12 | Dual Functional Diblock Amino Acid Copolymer Displaying Synergistic Effect with Curcumin against MRSA and Encapsulation of Curcumin显示文摘The intensive use of antibiotics intensifies the development of bacterial resistance,which has become a serious problem globally.Methicillin-resistant Staphylococcus aureus(MRSA)has resulted in significant morbidity and mortality.Therefore,it is an urgent need to develop new antimicrobial drugs and administration methods.Herein,we report a dual functional diblock copolymer PLL20-b-PBLG20,which was prepared by superfast and water-insensitive polymerization on N-carboxyanhydrides(NCA)initiated by tetraalkylammonium carboxylate.In addition to direct antimicrobial activity,PLL20-b-PBLG20 also exerts a synergistic bactericidal effect against MRSA with curcumin,a plant extract with antibacterial property.Moreover,PLL20-b-PBLG20 successfully encapsulates curcumin to form nanoparticles via self-assembly.The combination of dual functional PLL20-b-PBLG20 and curcumin holds promise in combating MRSA infections. | Yueming Wu Yuan Chen Haowen Yu Alideertu Dong Runhui Liu | 2023 | Chinese Journal of Chemistry2023，41，23： | 0 |
| 13 | Design of multilayer cellular neural network based on memristor crossbar and its application to edge detection显示文摘Memristor with memory properties can be applied to connection points(synapses)between cells in a cellular neural network(CNN).This paper highlights memristor crossbar-based multilayer CNN(MCM-CNN)and its application to edge detection.An MCM-CNN is designed by adopting a memristor crossbar composed of a pair of memristors.MCM-CNN based on the memristor crossbar with changeable weight is suitable for edge detection of a binary image and a color image considering its characteristics of programmablization and compactation.Figure of merit(FOM)is introduced to evaluate the proposed structure and several traditional edge detection operators for edge detection results.Experiment results show that the FOM of MCM-CNN is three times more than that of the traditional edge detection operators. | YU Yongbin TANG Haowen FENG Xiao WANG Xiangxiang HUANG Hang | 2023 | Journal of Systems Engineering and Electronics2023，34，3： | 0 |
| 14 | Down-regulation of N-methyl-D-aspartate receptor subunits 1 affects neurogenesis of hippocampal neural stem cells显示文摘Schizophrenia is a common and serious mental illness characterized by severe impairments in thinking,emotions,and behaviors.Usually,the cognitive deficits of schizophrenia are closely associated with abnormal neurogenesis due to the hypofunction of certain neural receptors such as N-methyl-D-aspartate receptors(NMDARs),which mediates neurotransmission.However,little is known about the involvement of NMDAR1 in regulating hippocampal neurogenesis in schizophrenia.In the current study,we present evidence suggesting that NMDAR1 regulates hippocampal neurogenesis as lentivirus-mediated shRNA silencing NMDAR1 gene or blocking with MK-801 results in abnormal neurogenesis consistently found in schizophrenia.The important finding was clearly demonstrated by the multiparametric assessments,including morphology,immunofluorescence,western blotting,and flow cytometry.Simultaneously,our results indicated that knockdown and blockade of NMDAR1 significantly attenuated the proliferation of hippocampal neural stem cells(hNSCs)and decreased the differentiation to neurons.More importantly,the blockade of NMDAR1 with MK-801 aggravated the apoptosis of hNSCs.Thus,it is likely that NMDAR1 functions as a new target for the treatment of schizophrenia.Our present study may provide a novel insight for further investigation of the pathogenesis of schizophrenia. | YUQING HE LI GUO JUAN DING HAOWEN LV QUANRUI MA CHEN LI YU SHAO QIANG LIU CHUN ZHANG HAO YANG JUAN LIU | 2021 | BIOCELL2021，45，2： | 0 |
| 15 | 全基因组关联研究发现中国人群前列腺癌两个新易感位点9q31.2和19q13.4显示文摘0前言在全球范围内,前列腺癌的发病率和病死率存在着巨大差异。该病在西方发达国家发病率最高,在非裔美国人群病死率最高,而在亚洲人群中发病率及病死率均为全球最低,提示不同人种在前列腺癌的遗传方面存在异质性。在欧美和日本人群中,全基因组关联研究(GWAS)技术已经被用于检测前列腺癌的遗传易感性位点,但至今尚无关于GWAS检测中国人群前列腺癌易感位点的报道。 | Jianfeng Xu Zengnan Mo Dingwei Ye Meilin Wang Fang Liu Guangfu Jin Chuanliang Xu Xiang Wang Qiang Shao Zhiwen Chen Zhihua Tao Jun Qi Fangjian Zhou Zhong Wang Yaowen Fu Dalin He Qiang Wei Jianming Guo Denglong Wu Xin Gao Jianlin Yuan Gongxian Wang Yong Xu Guozeng Wang Haijun Yao Pei Dong Yang Jiao Mo Shen Jin Yang Jun Ou-Yang Haowen Jiang Yao Zhu Shancheng Ren Zhengdong Zhang Changjun Yin Xu Gao Bo Dai Zhibin Hu Yajun Yang Qijun Wu Hongyan Chen Peng Peng Ying Zheng Xiaodong Zheng Yongbing Xiang Jirong Long Jian Gong Rong Na Xiaoling Lin Hongjie Yu Sha Tao Junjie Feng Jishan Sun Wennuan Liu Ann Hsing Jianyu Rao Qiang Ding Fredirik Wiklund Henrik Gronberg Xiao-Ou Shu Wei Zheng Hongbing Shen Li Jin Rong Shi Daru Lu Xuejun Zhang Jielin Sun S Lilly Zheng Yinghao Sun | 2013 | 第二军医大学学报2013，34，4： | 0 |
| 16 | A facile process to optimize performance of regenerated Nd-Fe-B sintered magnets:Chemo-selective dissolution washing显示文摘In this work,the recycled Nd-Fe-B powders and regenerated Nd-Fe-B sintered magnets with low impurity content were successfully prepared from Nd-Fe-B magnet sludge via reduction diffusion(RD)method followed by a chemo-selective dissolution washing proc ess.The chemo-selective dissolution effect of various solution(deionized water,dilute acetic acid solution,NH_(4)Cl-methanol solution) was evaluated by impurity content and magnetic properties of the recycled Nd-Fe-B powder.The NH_(4)Cl-methanol solution can selectively remove impurities with minimal damage to the magnetic phase.Besides,the optimal NH_(4)Cl concentration and liquid-to-solid ratio were investigated.As a consequence,the contents of Ca,O,and H after optimal washing process are reduced to 0.07 wt%,0.31 wt% and 0.22 wt%,respectively.Hence,M_(3) Tis increased to 146.72 emu/g,which is 33% higher than that of the initial sludge.Then,the regenerated Nd-Fe-B sintered magnets with properties of B_(r)=11.66 kG,H_(cj)=16.49 kOe,and(BH)_(m)=31.78 MGOe were successfully prepared by mixing with 40 wt% Nd4Fe14B alloy powders.Compared with the corresponding regenerated magnets washed with deionized water,the remanence and coercivity are increased by 18% and 59%,respectively. | Haibo Xu Qingmei Lu Lichao Yu Liying Cong Haowen Tian Weiqiang Liu Youhao Liu Yunqiao Wang Jingwu Chen Xiaofei Yi Qiong Wu Ming Yue | 2023 | Journal of Rare Earths2023，41，12： | 0 |
| 17 | Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation显示文摘Oxidative phosphorylation(OXPHOS)consumes oxygen to produce ATP.However,the mechanism that balances OXPHOS activity and intracellular oxygen availability remains elusive.Here,we report that mitochondrial protein lactylation is induced by intracellular hypoxia to constrain OXPHOS.We show that mitochondrial alanyl-tRNA synthetase(AARS2)is a protein lysine lactyltransferase,whose proteasomal degradation is enhanced by proline 377 hydroxylation catalyzed by the oxygen-sensing hydroxylase PHD2.Hypoxia induces AARS2 accumulation to lactylate PDHA1 lysine 336 in the pyruvate dehydrogenase complex and carnitine palmitoyltransferase 2(CPT2)lysine 457/8,inactivating both enzymes and inhibiting OXPHOS by limiting acetyl-CoA influx from pyruvate and fatty acid oxidation,respectively.PDHA1 and CPT2 lactylation can be reversed by SIRT3 to activate OXPHOS.In mouse muscle cells,lactylation is induced by lactate oxidation-induced intracellular hypoxia during exercise to constrain high-intensity endurance running exhaustion time,which can be increased or decreased by decreasing or increasing lactylation levels,respectively.Our results reveal that mitochondrial protein lactylation integrates intracellular hypoxia and lactate signals to regulate OXPHOS. | Yunzi Mao Jiaojiao Zhang Qian Zhou Xiadi He Zhifang Zheng Yun Wei Kaiqiang Zhou Yan Lin Haowen Yu Haihui Zhang Yineng Zhou Pengcheng Lin Baixing Wu Yiyuan Yuan Jianyuan Zhao Wei Xu Shimin Zhao | 2024 | Cell Research2024，34，1： | 0 |
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