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| 1 | A high strength, anti-fouling, self-healable, and thermoplastic supramolecular polymer hydrogel with low fibrotic response显示文摘The fibrotic response plays an important role in the performance and longevity of implantable devices. Thus, development of effective anti-inflammatory and anti-fibrosis biomaterial implants has become an urgent task. In this work, we developed a novel supramolecular polymer hydrogel through the copolymerization of N-acryloyl glycinamide(NAGA) and carboxybetaine acrylamide(CBAA) in the absence of any chemical crosslinker, which the mechanical properties being tunable through changing the monomer concentration and the monomer ratio over a broad scope. The hydrogel possessed the superior mechanical performances: high tensile strength(~1.13 MPa), large stretchability(~1200%), and excellent compressive strength(~9 MPa) at high monomer concentration and NAGA/CBAA ratio. Introduction of CBAA could promote the self-healability, thermoplasticity of suparmolecular polymer hydrogels at lower temperatures, meanwhile dramatically improving anti-fouling property.Histological analysis and in vitro cytotoxicity assays testified the excellent biocompatibility of the hydrogel. This high strength supramolecular polymer hydrogel with integrated multiple functions holds promising potentials as a scaffold biomaterial for treating degenerated soft supporting tissues. | WANG HongBo LI HaoFei WU YuanHao YANG JianHai LIU WenGuang | 2019 | Science China(Technological Sciences)2019，62，4： | 11 |
| 2 | Fluid structure interaction simulation of supersonic parachute inflation by an interface tracking method显示文摘An Arbitrary Lagrangian-Eulerian(ALE)approach with interface tracking is developed in this paper to simulate the supersonic parachute inflation.A two-way interaction between a nonlinear finite element method and a finite volume method is accomplished.In order to apply this interface tracking method to problems with instantaneous large deformation and self-contact,a new virtual structure contact method is proposed to leave room for the body-fitted mesh between the contact structural surfaces.In addition,the breakpoint due to the fluid mesh with negative volume is losslessly restarted by the conservative interpolation method.Based on this method,fluid and structural dynamic behaviors of a highly folded disk-gap-band parachute are obtained.Numerical results such as maximum Root Mean Square(RMS)drag,general canopy shape and the smallest canopy projected areas in the terminal descent state are in accordance with the wind tunnel test results.This analysis reveals the inflation law of the disk-gap-band parachute and provides a new numerical method for supersonic parachute design. | Xue YANG Li YU Min LIU Haofei PANG | 2020 | Chinese Journal of Aeronautics2020，33，6： | 5 |
| 3 | Disulfide-Containing Molecular Sticker Assists Cellular Delivery of DNA Nanoassemblies by Bypassing Endocytosis显示文摘The delivery efficiency of DNA nanoassemblies to the cytosol remains unsatisfactory due to endoand lysosomal entrapment and degradation,which restricts their bioanalytical and biomedical applications.Herein,the authors developed a disulfide-containing molecular sticker(DSMS)assisted approach to achieve efficient cytosolic delivery of DNA nanoassemblies.DSMS is designed to consist of a disulfide unit for thiol-mediated uptake and a guanidinium cation unit for strongly adhering to DNA nanoassemblies.After attaching with DSMS,a set of DNA nanoassemblies maintained their original three-dimensional features but had a different cellular internalization pathway.These results demonstrated that DSMS-DNA nanoassemblies complex did not enter the cells via endocytosis but instead entered through thiol-mediated direct uptake.Taking advantages of this facile assembly,universal applicability,and direct cytosolic delivery,DSMS might serve as a potent agent to facilitate the applications of DNA nanoassemblies in a variety of fields,such as bioimaging,drug delivery,and gene therapy. | Wen Yang Xiaochen Liu Haofei Li Jie Zhou Shan Chen Pengfei Wang Juan Li Huanghao Yang | 2021 | CCS Chemistry2021，3，3： | 2 |
| 4 | Is oral microbiome of children able to maintain resistance and functional stability in response to short-term interference of ingesta?显示文摘Dear Editor,A series of studies had focused on the ecological stability of human microbiome(Lozupone et al.,2012;Faith et al.,2013;Moya and Ferrer,2016).Despite the continuous perturbation and the highly personalized composition within the human microbiome(Human Microbiome Project,2012),healthy adults stably maintain their microbial communities in terms of space and time(Faith et al.,2013;Moya and Ferrer,2016;Oh et al.,2016).This stability is proved to be critical for the well-being of human body(Lozupone et al.,2012).On the contrary,major shifts in microbial community composition are often related to diseases(Lynch and Pedersen,2016). | Fangqiao Wei Xiangyu Sun Yufeng Gao Haoyu Dou Yang Liu Lili Su Haofei Luo Ce Zhu Qian Zhang Peiyuan Tong Wen Ren Zhe Xun Ruochun Guo Yuanlin Guan Shenghui Li Yijun Qi Junjie Qin Feng Chen Shuguo Zheng | 2021 | Protein & Cell2021，12，6： | 1 |
| 5 | Mobile ARGONAUTE 1d binds 22-nt miRNAs to generate phasiRNAs important for low-temperature male fertility in rice显示文摘Phased small interfering RNAs(phasiRNAs) are abundantly expressed in anthers and linked to environment-related male fertility in grasses, yet how they function under different environmental conditions remains unclear. Here, we identified a rice(Oryza sativa) low temperature-induced Argonaute(AGO) protein, OsAGO1d, that is responsible for generating phasiRNAs and preserving male fertility at low temperature. Loss of OsAGO1d function causes low-temperature male sterility associated with delayed programmed cell death of tapetal cells during anther development. OsAGO1d binds miR2118 and miR2275 family members and triggers phasiRNA biogenesis;it also binds 21-nt phasiRNAs with a 5′ terminal U. In total, phasiRNAs from 972loci are OsAGO1d-dependent. OsAGO1d protein moves from anther wall cells into meiocytes, where it loads miR2275 to produce 24-nt phasiRNAs. Together, our results show that OsAGO1d acts as a mobile signal to fine-tune phasiRNA production and this function is important for male fertility at low temperature. | Fuyan Si Haofei Luo Chao Yang Jie Gong Bin Yan Chunyan Liu Xianwei Song Xiaofeng Cao | 2023 | Science China(Life Sciences)2023，66，2： | 1 |
| 6 | In situ coordina- tion-induced Langmuir film formation of water-soluble 2, 5-dimercapto-1,3,4-thiadiazole at the air/water interface and the growth of metal sulfide nanostructures in their templated Langmuir-schaefer films 显示文摘 | Gong Haofei Yin Meifang Liu Minghua | 2003 | Langmuir2003，19，： | 1 |
| 7 | Effect of herba centellae on the expression of HGF and MCP-1显示文摘 | Zhu Zhang Guangce Wang Jiwei Ma Haofei Liu Xitao Zhang Guangling Zhu | 2013 | Experimental and Therapeutic Medicine2013，，2： | 1 |
| 8 | MSVM Recognition Model for Dynamic Process Abnormal Pattern Based on Multi-kernel Functions显示文摘 | Liu Yumin Zhou Haofei | 2014 | Journal of Systems Science and Information2014，2，5： | 1 |
| 9 | Thoracic Endovascular Aortic Repair for Type B Aortic Dissection显示文摘The incidence of aortic dissection(AD)is estimated to be 1 in 100,000 per year.The onset and progression of AD are rapid.Failure to receive appropriate treatment might lead to death in a short time.Even following active treatment,patients might develop low cardiac output syndrome,severe infection,and hemorrhage,which lead to death.Interventional therapy is a surgical method that has been widely used in Stanford type B AD recently.It is characterized by minimal invasiveness,low incidence of postoperative complications,and low cost.This article will review the interventional treatments for AD and will guide the selection of treatment options. | Yanqin Ruan Haofei Li Chang Liu | 2022 | Journal of Advances in Medicine Science2022，5，2： | 1 |
| 10 | Telomere-to-telomere genome of the allotetraploid legume Sesbania cannabina reveals transposon-driven subgenome divergence and mechanisms of alkaline stress tolerance显示文摘Alkaline soils pose an increasing problem for agriculture worldwide,but using stress-tolerant plants as green manure can improve marginal land.Here,we show that the legume Sesbania cannabina is very tolerant to alkaline conditions and,when used as a green manure,substantially improves alkaline soil.To understand genome evolution and the mechanisms of stress tolerance in this allotetraploid legume,we generated the first telomere-to-telomere genome assembly of S.cannabina spanning~2,087 Mb.The assembly included all centromeric regions,which contain centromeric satellite repeats,and complete chromosome ends with telomeric characteristics.Further genome analysis distinguished A and B subgenomes,which diverged approximately 7.9 million years ago.Comparative genomic analysis revealed that the chromosome homoeologs underwent large-scale inversion events(>10 Mb)and a significant,transposon-driven size expansion of the chromosome 5A homoeolog.We further identified four specific alkali-induced phosphate transporter genes in S.cannabina;these may function in alkali tolerance by relieving the deficiency in available phosphorus in alkaline soil.Our work highlights the significance of S.cannabina as a green tool to improve marginal lands and sheds light on subgenome evolution and adaptation to alkaline soils. | Haofei Luo Xiaofei Wang Changqing You Xuedan Wu Duofeng Pan Zhiyao Lv Tong Li Dongmei Zhang Zhongbao Shen Xiaodong Zhang Guodao Liu Kaixuan He Qingtong Ye Yajun Jia Qinghua Zhao Xian Deng Xiaofeng Cao Xianwei Song Gai Huang | 2024 | Science China(Life Sciences)2024，67，1： | 0 |
| 11 | Isobaric Vapor–Liquid Equilibrium for tert-Butyl Alcohol + Water + Propane-1,3-Diol + 1-Ethyl-3-Methylimidazolium Chloride at 101.3 kPa显示文摘In this study, we used a mixture of organic liquid propane-1,3-diol and ionic liquid 1-ethyl-3-methylimidazolium chloride([emim]Cl) as the entrainer to separate tert-butyl alcohol(TBA) + water. We measured the isobaric vapor–liquid equilibrium(VLE) for the quaternary system TBA + water + propane-1,3-diol + [emim]Cl at 101.3 kPa, and found the VLE data to be well correlated with the nonrandom two-liquid model. These results show that the mixed solvent of propane-1,3-diol + [emim]Cl can increase the relative volatility of TBA to water and break the azeotropic point. We found no notable synergetic effect between them, and observed that the liquid mixed solvent of propane-1,3-diol and [emim]Cl had lower viscosity than [emim]Cl, which makes it a promising entrainer for separating the TBA + water azeotrope in industrial applications. | Xianbao Cui Qinglong Cheng Haofei Liu Lexing Xue Jinbo Zhou Ying Zhang Tianyang Feng Kai Zhang | 2018 | Transactions of Tianjin University2018，24，5： | 0 |
| 12 | New insights into the formation of ammonium nitrate from a physical and chemical level perspective显示文摘High levels of fine particulate matter(PM_(2.5))is linked to poor air quality and premature deaths,so haze pollution deserves the attention of the world.As abundant inorganic components in PM_(2.5),ammonium nitrate(NH_(4)NO_(3))formation includes two processes,the diffusion process(molecule of ammonia and nitric acid move from gas phase to liquid phase)and the ionization process(subsequent dissociation to form ions).In this study,we discuss the impact of meteorological factors,emission sources,and gaseous precursors on NH4NO3 formation based on thermodynamic theory,and identify the dominant factors during clean periods and haze periods.Results show that aerosol liquid water content has a more significant effect on ammonium nitrate formation regardless of the severity of pollution.The dust source is dominant emission source in clean periods;while a combination of coal combustion and vehicle exhaust sources is more important in haze periods.And the control of ammonia emission is more effective in reducing the formation of ammonium nitrate.The findings of this work inform the design of effective strategies to control particulate matter pollution. | Yuting Wei Xiao Tian Junbo Huang Zaihua Wang Bo Huang Jinxing Liu Jie Gao Danni Liang Haofei Yu Yinchang Feng Guoliang Shi | 2023 | Frontiers of Environmental Science & Engineering2023，17，11： | 0 |
| 13 | Interdecadal variability in ecosystem health of Changjiang (Yangtze) River estuary using estuarine biotic integrity index显示文摘Ichthyoplankton samples were collected from Changjiang(Yangtze)River estuary in May 2016.Species composition was studied by DNA barcoding and morphological identification.To make better use of the estuarine biotic integrity index(EBI)to assess the ecosystem health of the Changjiang River estuary over the past 30 years,we collected the data of a spring ichthyoplankton survey in the estuary from 1986 to 2016.The EBI was calculated using 12 evaluation metrics,namely,the number of total ichthyoplankton species,estuarine spawning species,estuarine nursery species,estuarine resident species,benthic species,pelagic species,and intolerant species,and the percentages of tolerant species,omnivores,insectivores,carnivores,and natural hybrid species.EBI was calculated in spring in four periods(1986,1999,2007,and 2016)by assigning points of 1,3 or 5,giving values of 50,38,36,and 32,respectively,corresponding to“Good”,“Fair-Poor”,“Fair-Poor”,and“Poor”EBI levels,respectively.Changes in species composition were the primary reason for the significant decreases in EBI between 1986 and 1999,and for the large differences between 1986 and 2007 and between 2007 and 2016.The changes in species composition were influenced by declines in ichthyoplankton species,pollution sensitive species,estuarine nursery species and estuarine sedentary species,and an increase in pollution resistant species.An analysis of EBI interdecadal variability showed that the health status of the Changjiang River estuary ecosystem over the last 30 years first declined and then stabilized at a lower level.This result further settled the argument for urgent protection and restoration of the Changjiang River estuary. | Shouhai LIU Haijing ZHANG Yanlong HE Xiangsheng CHENG Haofei ZHANG Yutao QIN Xi JI Riguang HE Yaohui CHEN | 2021 | Journal of Oceanology and Limnology2021，39，4： | 0 |
| 14 | Soil splash erosion:An overlooked issue for sustainable rubber plantation in the tropical region of China显示文摘Soil erosion by water is known to be a major driver of land degradation.Splash erosion is the initial stage of water erosion and directly contributes to the detachment of soil particles on sloping land.Splash erosion may be exacerbated or mitigated by ongoing land use/cover change.To estimate the effects of various land use and management systems on splash erosion in the humid tropics,we measured the actual splash erosion under natural rainfall conditions in a tropical rainforest(TR),rubber monoculture(RM),and four rubber agroforestry ecosystems in Xishuangbanna,Southwestern China.The average cumulative splash mass in the RM was 48.7 times higher compared to that in the TR,indicating that the replacement of TR by RM results in severe splash erosion.In the rubber agroforestry systems,the throughfall kinetic energy and splash mass were 34-76%and 86-97%lower,respectively,than that in the RM,indicating that intercropping crops with rubber trees can effectively alleviate erosive power of throughfall and thus splash erosion.Under all land use regimes,in the plots where the litter layer was removed,splash erosion was significantly(2.0-12.1 times)higher and more spatially heterogeneous than in those with litter cover.This highlighted the key role of the forest litter layer in protecting the soil from raindrop detachment.In the study area,the actual splash erosion was strongly correlated with the conditions of precipitation(amount and intensity(I10)of rainfall)and the vegetation structure(especially the crown base height,leaf area index,and canopy cover),but weakly correlated with the soil properties.Given the importance of near-ground intercrops(height<5 m)for improving the vegetation structure,surface cover,and soil conditions,the intercropping of Camellia sinensis and Theobroma cacao with rubber trees is a promising approach for controlling splash erosion and also has benefits on the sus-tainable development of rubber plantation. | Xiai Zhu Xia Yuan Enfu Lu Bin Yang Haofei Wang Yiyuan Du Ashutosh Kumar Singh Wenjie Liu | 2023 | International Soil and Water Conservation Research2023，11，1： | 0 |
| 15 | The Development of Soybean Byproducts in Heilongjiang, China显示文摘 | Guixing Zhao Lijun Liu Xia Chen Haofei Liu Chunj ie Zhao Yi Tan | 2010 | Journal of Life Sciences2010，4，7： | 0 |
| 16 | Effects of light intensity and photoperiod on the growth performance of juvenile Murray cods(Maccullochella peelii)in recirculating aquaculture system(RAS)显示文摘Murray cod(Maccullochella peelii)is a freshwater percichthyid fish that has a high market value and potential for culture in recirculating aquaculture systems(RASs).Illumination is an important environmental factor that affects the growth and physiological condition of fishes.A comprehensive understanding of the relationship between the light factors and the growth,nutrient composition and stress response of juvenile Murray cod in RAS is important to achieve satisfactory theoretical and practical aquaculture performance.Juvenile Murray cod were randomly assigned to nine RAS tanks with a volume of 1.5 m^(3),with each tank containing 120 fishes(3.5±0.5g).The fish were cultured for 120 days under different light intensities(1200,2400,and 3600 lx)and photoperiods(12L:12D,18L:6D and 24L:0D).The results showed that the final weight and feed conversion ratio of Murray cod under a light intensity of 1200 lx were significantly better than those under 3600 lx(P<0.05).The serum total protein and globulin were higher at the light intensity of 1200lx,compared to other light intensities.The blood urea nitrogen level improved with increasing light intensity at LD12:12 and LD18:6 of photoperiod,as well as the superoxide dismutase level improved significantly from LD18:6 to LD24:0 of photoperiod.The findings indicated that the optimal light condition to enhance growth at juvenile stage is 1200 lx of the light intensity and LD18:6 of the photoperiod. | Zhengkai Di Kang Li Tiezhu Li Li Yan Haofei Jiang Liping Liu | 2023 | Aquaculture and Fisheries2023，8，3： | 0 |
| 17 | A novel bioartificial pancreas fabricated via islets microencapsulation in anti-adhesive core-shell microgels and macroencapsulation in a hydrogel scaffold prevascularized in vivo显示文摘Islets transplantation is a promising treatment for type 1 diabetes mellitus. However, severe host immune rejection and poor oxygen/nutrients supply due to the lack of surrounding capillary network often lead to transplantation failure. Herein, a novel bioartificial pancreas is constructed via islets microencapsulation in core-shell microgels and macroencapsulation in a hydrogel scaffold prevascularized in vivo. Specifically, a hydrogel scaffold containing methacrylated gelatin (GelMA), methacrylated heparin (HepMA) and vascular endothelial growth factor (VEGF) is fabricated, which can delivery VEGF in a sustained style and thus induce subcutaneous angiogenesis. In addition, islets-laden core-shell microgels using methacrylated hyaluronic acid (HAMA) as microgel core and poly(ethylene glycol) diacrylate (PEGDA)/carboxybetaine methacrylate (CBMA) as shell layer are prepared, which provide a favorable microenvironment for islets and simultaneously the inhibition of host immune rejection via anti-adhesion of proteins and immunocytes. As a result of the synergistic effect between anti-adhesive core-shell microgels and prevascularized hydrogel scaffold, the bioartificial pancreas can reverse the blood glucose levels of diabetic mice from hyperglycemia to normoglycemia for at least 90 days. We believe this bioartificial pancreas and relevant fabrication method provide a new strategy to treat type 1 diabetes, and also has broad potential applications in other cell therapies. | Haofei Li Yulian Shang Qi Feng Yang Liu Junlin Chen Hua Dong | 2023 | Bioactive Materials2023，，9： | 0 |
| 18 | Carbon-Involved Near-Surface Evolution of Cobalt Nanocatalysts:An in Situ Study显示文摘When carbon-containing species are involved in reactions catalyzed by transition metals at high temperature,the diffusion of carbon on or in catalysts dramatically influences the catalytic performance.Acquiring information on the carbon-diffusioninvolved evolution of catalysts at the atomic level is crucial for understanding the reaction mechanism yet also challenging.For the chemical vapor deposition process of single-walled carbon nanotubes(SWCNTs),we recorded in situ the catalyst state(solid and molten)composition as well as near-surface structural and chemical evolution at the cobalt catalyst-tube interface with carbon permeation using aberration-corrected environmental transmission electron microscopy and synchrotron X-ray absorption spectroscopy.The nucleation of SWCNTs was linked with an alternating dissolving and precipitating cycle of carbon in catalysts close to the nucleation site.Understanding the dynamics of carbon atoms in catalysts brings deeper insight into the growth mechanism of SWCNTs and facilitates inferring mechanisms of other reactions.The methodologies developed here will find broad applications in studying catalytic and other processes. | Feng Yang Haofei Zhao Wu Wang Qidong Liu Xu Liu Yuecong Hu Xinrui Zhang Sheng Zhu Dongsheng He Yingying Xu Jiaqing He Rongming Wang Yan Li | 2021 | CCS Chemistry2021，3，11： | 0 |
| 19 | Hydrogen-bonded organic framework for red light-mediated photocatalysis显示文摘The development of heterogeneous molecule-based catalysts for red light-mediated photocatalysis is still challenging due to the improper light absorption for most materials and the photoactivity deactivation for solid assembly.Herein,red light photocatalysis with a hydrogen-bonded organic framework(HOF)is established.This HOF,named HOF-66,is formed from the self-assembly of guanine-decorated naphthalenediimide(NDI)molecule through hydrogen-bonded guanine-quadruplex nodes,showing square grid supramolecular layers confirmed by powder X-ray diffraction analysis.In contrast to unsubstituted NDI HOF,introduction of ethylamino groups to NDI core in HOF-66 tunes strong electronic maximum absorption peak to 619 nm,allowing red light photocatalysis of singlet oxygen evolution proved by 1,3-diphenylisobenzofuran degradation and electron spin resonance determination.Particularly,under the same conditions,the sulfide oxidation rate in the presence of HOF-66 was 28 times higher compared to its unsubstituted analogue.This work integrates the molecular design and aggregation effect towards the application of HOFs,opening a new gate for red light photocatalysts. | Haofei Zhao Ziwen Zhou Xuenan Feng Chao Liu Hui Wu Wei Zhou Hailong Wang | 2023 | Nano Research2023，16，7： | 0 |
| 20 | Analysis of a Synechococcus sp. Bloom in the East China Sea and Its Causes显示文摘In the spring of 2007,a Synechococcus sp. bloom was monitored in station A1( 30° N,123° E) in the East China Sea. The abundance of Synechococcus sp. was nearly 2×10~6 cells/ml,and the contribution of Synechococcus sp. to chlorophyll a was nearly 90%. According to the abundance of Synechococcus sp. in the East China Sea and adjacent Changjiang River estuary in the past tow decades,the main reasons why Synechococcus sp. could form a bloom are listed below: the rising level of nutrients and the further eutrophication of the water body provided sufficient nutrients for Synechococcus sp.;with the global warming,the sea water temperature in the East China Sea rose continuously;the number of major predator heterotrophic flagellates was at a low level,reducing predation pressure. | Haofei ZHANG Caicai LIU Bangping DENG | 2020 | Meteorological and Environmental Research2020，11，3： | 0 |
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