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| 1 | Type 2 diabetes mellitus:From a metabolic disorder to an inflammatory condition显示文摘Diabetes mellitus is increasing at an alarming rate and has become a global challenge.Insulin resistance intarget tissues and a relative deficiency of insulin secretion from pancreatic β-cells are the major features of type 2 diabetes(T2D).Chronic low-grade inflammation in T2 D has given an impetus to the field of immuno-metabolism linking inflammation to insulin resistance and β-cell dysfunction.Many factors advocate a causal link between metabolic stress and inflammation.Numerous cellular factors trigger inflammatory signalling cascades,and as a result T2 D is at the moment considered an inflammatory disorder triggered by disordered metabolism.Cellular mechanisms like activation of Tolllike receptors,Endoplasmic Reticulum stress,and inflammasome activation are related to the nutrient excess linking pathogenesis and progression of T2 D with inflammation.This paper aims to systematically review the metabolic profile and role of various inflammatory pathways in T2 D by capturing relevant evidence from various sources.The perspectives include suggestions for the development of therapies involving the shift from metabolic stress to homeostasis that would favour insulin sensitivity and survival of pancreatic β-cells in T2 D. | Iqra Hameed Shariq R Masoodi Shahnaz A Mir Mudasar Nabi Khalid Ghazanfar Bashir A Ganai | 2015 | World Journal of Diabetes2015，6，4： | 36 |
| 2 | Diffusion weighted magnetic resonance imaging of liver: Principles, clinical applications and recent updates显示文摘Diffusion-weighted imaging(DWI), a functional imaging technique exploiting the Brownian motion of water molecules, is increasingly shown to have value in various oncological and non-oncological applications. Factors such as the ease of acquisition and ability to obtain functional information in the absence of intravenous contrast, especially in patients with abnormal renal function, have contributed to the growing interest in exploring clinical applications of DWI. In the liver, DWI demonstrates a gamut of clinical applications ranging from detecting focal liver lesions to monitoring response in patients undergoing serial follow-up after loco-regional and systemic therapies. DWI is also being applied in the evaluation of diffuse liver diseases such as non-alcoholic fatty liver disease, hepatic fibrosis and cirrhosis. In this review, we intend to review the basic principles, technique, current clinical applications and future trends of DW-MRI in the liver. | Anuradha Shenoy-Bhangle Vinit Baliyan Hamed Kordbacheh Alexander R Guimaraes Avinash Kambadakone | 2017 | World Journal of Hepatology2017，9，26： | 21 |
| 3 | Automatic extraction of tank outlets in a sub-watershed using digital elevation models显示文摘 | Nisar A hamed T R Gopal Rao K Murthy J S R | 2002 | Agricultural Water Management2002，57，3： | 1 |
| 4 | Role of computerised tomography in management of intra-articular fractures of the os calcis显示文摘 | KUMAR V HAMEED A BHATTACHARYA R | 2006 | Int Orthop2006，30，2： | 1 |
| 5 | Variation in corn stover composition and energy content with crop maturity 显示文摘 | PORDESIMO L O HAMES B R SOKHANSANJ S | 2005 | Biomass and Bioener- gy2005，28，4： | 1 |
| 6 | Brucella meningitis 显示文摘 | Hamed R A R Reza A Mohammad S | 2013 | Med J Islam Repub Iran2013，27，2： | 1 |
| 7 | The Role of Climate for Innovation in En- hancing Business Performance: The Case of Design Firms显示文摘 | PANUWATWANICH K STEWART R A MO- HAMED S | 2008 | Engineering Construction and Architectur- al Management2008，15，5： | 1 |
| 8 | A modified Mann - Kendall trend test forautocorrelated data 显示文摘 | HAMED K H RAO A R | 1998 | Journal of Hydrology1998，204，： | 1 |
| 9 | Input-output linearisation of a fourth-order input-affine system describing the evolution of a three-phase/switch/level(Vienna) rectifier显示文摘 | ANSARI R FEYZI M R AKBARI HAMED K | 2011 | Power Electronics IET2011，4，8： | 1 |
| 10 | Peel mechanics for an elastic-plastic adherend 显示文摘 | Gent A N Hamed G R | 1977 | J Appl Polymer Sci1977，21，： | 1 |
| 11 | Expression of IGF-Ⅰ splice variants in young and old human skeletal muscle after high resistance exercise显示文摘 | Hameed M Orrell R W Cobbold M | 2003 | Physiology-London2003，547，1： | 1 |
| 12 | The stability of cytadherence proteins in Mycoplasma pneumoniae requires ac tivity of the protein kinase PrkC显示文摘 | Schmidl S R Gronau K Hames C | 2010 | Infect lmmun2010，78，： | 1 |
| 13 | Study of cardiac and hemo- dynamic changes with airway pressure release ventilation and pressure control ventilation in ehildren with acute respiratory dis- tress syndrome显示文摘 | Hamed H Hagar A Gaber R | 2012 | Eur Respir J2012，40，9： | 1 |
| 14 | Peel mechanics for an elastic-plastic adherend显示文摘 | Gent A N Hamed G R | 1977 | J Appl Polymer Sci1977，21，： | 1 |
| 15 | Characterization of food waste as feedstock for anaerobic digestion显示文摘 | Zhang R H Hamed El-Mashad M Karl H | 2007 | Bioresource Technology2007，98，4： | 1 |
| 16 | Molecular aspects of the fatigue and fracture of rubber 显示文摘 | Hamed G R | 1994 | Rubber Chemistry and Technology1994，67，3： | 1 |
| 17 | A novel hybrid multi-objective shuffled frog-leaping algorithm for a bicriteria permutation flow shop scheduling problem显示文摘 | ALIREZA R V MOSTAFA D HAMED R | 2009 | International Journal of Advanced Manufacturing Technology2009，41，1112： | 1 |
| 18 | Treatment of idiopathic nephrotic syndrome with cyclosporin A in children显示文摘 | Hamed R M | | 0，，05： | 1 |
| 19 | Identification of pigment cellantigens defined by vitiligo antibodies 显示文摘 | Cui J Haming R Henn M | 1992 | J Invest Dermatol1992，98，2： | 1 |
| 20 | Effect of preparation conditions on the performance of nano Pt - CuO/C electrocatalysts for methanol electro - oxidation显示文摘 | Amin R S Abdel Hameed R M E1 -Khatib K M | 2012 | International Journal of Hydrogen Energy2012，3724，18： | 1 |
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