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    题名 作者 年代 出处 被引量
1Seed germination in Artemisia sphaerocephala II The influence of environmental factors显示文摘HuangZY(黄振英) GuttermanY HuZH(胡正海) ZhangXS(张新时) 植物生态学报0,,:1
2Free fatty acid receptor 2 promotes cardiomyocyte hypertrophy by activating STAT3 and GATA4显示文摘Free fatty acids(FFAs)play important roles in cardiovascular disease.Studies have shown that it is an important way for FAs to exert biological effects through their own receptors besides directly participating biochemical reaction in body.Free fatty acid receptor 2(FFA2)can be activated by short-chain FAs and is involved in inflammatory reactions and lipid accumulation.Since the known pathological changes caused by FFA2 are also implicated in cardiac hypertrophy,we hypothesized that FFA2 might be pathogenic in cardiac hypertrophy.This paper showed that FFA2 expression significantly increased in cardiac hypertrophy in vivo and in vitro.FFA2 agonist 4-CMTB or TUG-1375 promoted the expression of the hypertrophy markers ANF and BNP and increased cell surface area in vitro,which was further strengthened by FFA2 overexpression,suggesting that FFA2 might contribute to cardiomyocyte hypertrophy.Furthermore,4-CMTB treatment or FFA2 overexpression combined with 4-CMTB treatment elevated the phosphorylation and transcriptional activity of GATA4 and STAT3,which were inhibited by an ERK1/2 inhibitor,and GATA4 and STAT3 knockdown inhibited the elevation of hypertrophy biomarkers in cardiomyocytes treated with 4-CMTB.Taken together,these data indicate that FFA2 can enhance cardiomyocyte hypertrophy by activating STAT3 and GATA4 via ERK1/2,providing a potential new target for therapy.Hui Gao Kunming Tian Xiaojun Feng Mengqing Yan Chen Gao Yisheng Jiang Chenhao Zhu Huzhe Zhu Xueping Liu Yingfu Peng 2022Food Science and Human Wellness2022,11,2:1
3StudyOilthemor-pbologyanddistributionofEucommiarobberwire显示文摘DianXL(田兰馨) HuZH(胡正海) 1983西北大学学报自科版1983,,1:1
4显示文摘HuZhe(胡哲) SongXianhui(宋显辉) 固体力学学报0,,:1
5Application of PBL in physiologicalteaching 显示文摘HUZH MENG L HU YM 2003Journal of Shan Xi Medical University( Basic medical ed-ucation)2003,5,5:1
6StudyonthedynamicvariationoftotalflavonoidsindifferentorgansofBupleurumchinenseDC[J]显示文摘TANLL CAIX HUZH 2008中草药2008,39,2:1
7Forest vegetation types in Gutianshan Nature Reserve in Zhejiang显示文摘YuMJ(于明坚) HuZH(胡正华) YuJP(余建平) DingBY(丁炳扬) FangT(方腾) 浙江大学 学报(农业和生命科学版)0,,2001:1
8A profile of physicochemical and antioxidant changes during fruit growth for the utilisation of unripe apples显示文摘ZHENG Huzhe KIM YI CHUNG SK 2012Food Chem2012,131,:1
9Effect of exogenous salicylic acid on seed germination and seedling physiological characteristics of kidney bean(Phaseolus vulgaris L)under salt stress(外源水杨酸对盐胁迫下菜豆种子萌发和幼苗生理特性的影响)[J]显示文摘ZHANGFY(张凤银) CHENCY(陈禅友) HUZH(胡志辉) etal 2013东北农业大学学报自然科学版2013,44,10:1
10Identification of Polyphenols from Unripe Apple with Viscozyme L Extraction显示文摘As a potential source of fine chemicals, unripe apple polyphenols were extracted with Viscozyme L treatment. And then, a preparative moderate pressure liquid chromatography(MPLC) method for separation and purification of polyphenols were successfully established by using silica gel column and octadesyl silane column. The structures of these compounds were identified by ~1H and ^(13)C NMR spectroscopy. The results indicated that Viscozyme L had the strongest effect on polyphenols extraction, the yield of apple crude polyphenols(ACP) was 7.08%, and the total phenolic content(TPC) of ACP was 0.95 g GAE/100 g, which were 2 times of that of control; 5 sub-fractions were obtained from ACP, which were A-1, A-2, and B-1, B-2, B-3; fractions A-2 and B-2 were identified as p-coumaric acid and caffeic acid and the yields were 111.54 and 161.70 mg/100 g ACP, respectively. In addition, p-coumaric acid and caffeic acid were the major components in Viscozyme L-aided polyphenols extraction, which could be explained by the result of degradation of lignin and chlorogenic acid by carbohydrate-hydrolyzing enzyme, Viscozyme L.Huzhe ZHENG Chunlan CUI Shinkyo CHUNG 2019Agricultural Biotechnology2019,8,2:1
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