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896篇 您的检索式:作者名="HILLS G J"
    题名 作者 年代 出处 被引量
1Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van 1997Cell1997,,2:6
2Streptococcus suis serotypes characterized by analysis of chaperonin 60 gene sequences显示文摘Rousseau R Hill J E Prefontaine G 2001Appl Env Microbiol2001,67,:2
3Anti-hypertensive drugs in children and adolescents显示文摘Worldwide the prevalence of essential hypertension inchildren and adolescents continues to increase. Tradi-tionally providers have used 'off-label' drugs to treatpediatric hypertension, meaning that rigorous clinicaltrials of these drugs have not been specifically per-formed in pediatric patient populations. Consequentlyproviders have extrapolated dosing, safety and efficacyfrom trials in adults. This practice is sub-optimal as chil-dren demonstrate unique differences in drug metabo-lism and response. Use of unstudied or understudieddrugs increases risk of adverse events and/or can leadto sub-optimal efficacy. Recognizing these concerns,regulatory agencies have created financial incentivesfor industry to conduct pediatric clinical trials. Theseincentives, coupled with the emerging pediatric hyper-tension epidemic, have spurred over 30 clinical trialsof anti-hypertensive drugs over the past 15 years andhave resulted in labeling of 10 new drugs by the UnitedStates Food and Drug Administration for treatment ofhypertension in children and adolescents. Unfortunatelythe financial incentive structures focus on newer drugsand drug classes. Consequently there is now a relativedearth of trial data for older but sometimes commonlyprescribed pediatric antihypertensive drugs. This article reviews recent pediatric antihypertensive drug trials with a focus on trial design and endpoints, drug dosing, safety, efficacy and specific drug indications. We also review the available data and experience for some of the more commonly prescribed, but less well studied 'older' pediatric antihypertensive drugs.Patricia Y Chu Michael J Campbell Stephen G Miller Kevin D Hill 2014World Journal of Cardiology2014,6,5:2
4Attack structuralvulnerability of power grids s a hybrid approach based oncomplex networks显示文摘CHEN G DONG Z Y HILL D J 2010Physica A: Statistical Mechanics and ItsApplications2010,389,3:1
5Comprehensive assessment of perioperative fatigue: development of the Identity Consequence Fatigue Scale显示文摘Paddison J S Booth R J Hill A G 2006J Psychosom Res2006,60,14:1
6An overlap invariantentropy measure of 3D medical image alignment 显示文摘StudholmeC Hill D L G Hawkes D J 1999PatternRecognition1999,32,1:1
7Mutational analysis of the coat protein gene of potato virus X:effects on viron morphology and viral pathogenicity显示文摘 HILLS G WATTS J 1992Virology1992,191,:1
8A three-component deformation model for image-guided surgery显示文摘Edwards P J Hill D L G Little J A 1998Medical Image Analysis1998,2,4:1
9IV immunoglobulin is associated with a reduced risk of Alzheimer disease and related disorders显示文摘FILLIT H HESS G HILL J 2009Neurology2009,73,3:1
10Thermal challenge prob- lem: summary显示文摘Hills R G Dowding K J Swiler L 2008Computer Methods in Applied Mechanics and Engineering2008,197,2932:1
11Effect of vitamin E and selenium on iron utilization in neonatal pigs显示文摘Hill G M Link J E Meyer L 1999J Anim Sci1999,77,17:1
12Comparison of reducibility and stability of alumina-supported Ni catalysts prepared by impregnationand co-precipitation 显示文摘Li G H Hu L J Josephine M Hill 2006Appl Catal A2006,301,:1
13Definition and classification of power system stability 显示文摘KUNDUR P PASERBA J AJJARAPU V ANDERSSON G BOSE A CANIZARES C HATZIARGYRIOU N HILL D STANKOVICA TAYLOR C van CUTSEM T VITTAL V 2004IEEE Transactions on Power Systems2004,19,3:1
14Failure of early diag- nosis in symptomatic Duchenne muscular dystrophy显示文摘Bushby K M Hill A Steele J G 1999Lancet1999,353,9152:1
15Wet peroxide oxidation of sediments contaminated with PCBs 显示文摘Duffy J E Anderson M A Hill C G 2000Environ Sci Technol2000,34,15:1
16Non-rigid registration using higher-order mutual information 显示文摘Rueckert D Clarkson M J Hill D L G 2000Proceeding of SPIE2000,3979,2:1
17Crystal structure of a biliverdin Ⅸalpha reductase enzyme-cofactor complex显示文摘WHITBY F G PHILLIPS J D HILL C P 2002J Mol Biol2002,319,5:1
18Red clover vigour testing-effects of three test variables显示文摘Wang Y R Hampton J G Hill M J 1994Seed Science and Technology1994,22,:1
19Surface oxidation activates indium tin oxide for hole injection显示文摘Milliron D J Hill I G Shen C 2000J Appl Phys2000,87,1:1
20Insulin as a growth factor 显示文摘Hill D J Milner R D G 1985Rediatr Res1985,9,:1
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