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| 1 | Characterization of focal liver lesions with SonoVue~-enhanced sonography: International multicenter-study in comparison to CT and MRI显示文摘AIM: To evaluate in a multicenter study whether the sonographic characterization of focal liver lesions can be improved using SonoVueüà-enhancement; and to compare this method with computed tomography (CT) and magnetic resonance imaging (MRI). METHODS: One hundred and thirty four patients with one focal liver lesion detected in baseline ultrasound (US) were examined with conventional US, contrastenhanced US (n = 134), contrast-enhanced CT (n = 115) and/or dynamic contrast-enhanced MRI (n = 70). The lesions were classified as malignant, benign or indeterminate and the type of lesion was determined. The f inal diagnosis based on the combined information of all imaging examinations, clinical information and histology (n = 32) was used. Comparisons were made to see whether the addition of contrast-enhanced US led to the improvement of the characterization of doubtful focal liver lesions. RESULTS: In comparison with unenhanced US, SonoVue markedly improves sensitivity and specificity for the characterization (malignant/benign) of focal liver lesions. In comparison with CT and/or dynamic MRI, SonoVueüà -enhanced sonography applied for characterization of focal liver lesions was 30.2% more sensitive in the recognition of malignancy and 16.1% more specific in the exclusion of malignancy and overall 22.9% more accurate. In the subgroup with confirmative histology available (n = 30), sensitivity was 95.5% (CEUS), 72.2% (CT) and 81.8% (MRI), and specif icity was 75.0% (CEUS), 37.5% (CT) and 42.9% (MRI). The sensitivity and specif icity of CEUS for the identif ication of focal nodular hyperplasia (FNH) and hemangiomas was 100% and 87%, resulting in an accuracy of 94.5%. CONCLUSION: SonoVueüà-enhanced sonography emerges as the most sensitive, most specif ic and thus most accurate imaging modality for the characterization of focal liver lesions. | Hervé Trillaud Jean-Michel Bruel Pierre-Jean Valette Valérie Vilgrain Gérard Schmutz Raymond Oyen Wieslaw Jakubowski Jan Danes Vlastimil Valek Christian Greis | 2009 | World Journal of Gastroenterology2009，15，30： | 34 |
| 2 | Upper digestive intolerance during enteral nutrition in critically ill patients: Frequency, risk factors, and complications显示文摘 | Hervé Mentec Hervé Dupont Maria Bocchetti Pascale Cani Frédérique Ponche Gérard Bleichner | 2001 | Critical Care Medicine2001，，10： | 2 |
| 3 | Randomized Comparison of Strategies for Type B Aortic Dissection: The INvestigation of STEnt Grafts in Aortic Dissection (INSTEAD) Trial显示文摘 | Christoph A. Nienaber Hervé Rousseau Holger Eggebrecht Stephan Kische Rossella Fattori Tim C. Rehders Günther Kundt Dierk Scheinert Martin Czerny Tilo Kleinfeldt Burkhart Zipfel Louis Labrousse Hüseyin Ince | 2009 | Circulation2009，，25： | 2 |
| 4 | CD20 is associated with a small mature plasma cell morphology and t(11;14) in multiple myeloma显示文摘 | Nelly R Herve AL Richard G | 2003 | Blood2003，102，3： | 1 |
| 5 | Modification of the structural and redox properties of cytochrome by heteropoly tungstate binding显示文摘 | Chottard g Michelon M Herve M | 1987 | Biochim Biophys Acta1987，916，： | 1 |
| 6 | CT and MRI findings in primitive pituitary abscess: a case report and review of literature 显示文摘 | Sabbah P Bonardel G Herve R | 1999 | J Neuroradiol1999，26，3： | 1 |
| 7 | Condensation of gly-oxal with triethylenetetraamine:Stereochemistry,cyclizationand deprotection 显示文摘 | Herve G Bernard H Le Bris N | 1999 | Tetrahedron Letters*1999，40，13： | 1 |
| 8 | Study of a- and fl-enneatungsto- silicates and -germanates 显示文摘 | HERV]~ G TI~ZE A | 1977 | Inorg Chem1977，16，： | 1 |
| 9 | Finding drug targets in microbial genomes 显示文摘 | Timothy D R Steven R G Herve T | 2001 | Res Focus2001，6，17： | 1 |
| 10 | Long quadrilinear CCD sensors equipped with long linear filters-Characteristics and performances for the multispectral channel of earth observing systems显示文摘 | HERVE G JACQUES L ISABELLE L | | 0，，： | 1 |
| 11 | Formation et isomerisation des undeca et dodeea tungstosilcates et germanates isom-ers显示文摘 | Hervé G | 1997 | J Inorg Nucl Chem1997，39，14： | 1 |
| 12 | Ammonia-hardening of porous silica antireflective coatings显示文摘 | Belleville Philippe F Floch Herve G | 1994 | Spie Proc1994，2288，： | 1 |
| 13 | 显示文摘 | JASMIN C CHERMANN J C HERVE G | 1974 | J Nat Cancer Inst1974，53，： | 1 |
| 14 | 肺动脉高压启动治疗后血流动力学指标的预后价值显示文摘血流动力学指标,如心脏指数和右心房压力(right atrial pressure,RAP)与患者确诊肺动脉高压时的生存率持续相关。近期研究表明,肺动脉顺应性(pulmon aryarterial compliance,Pea)也可能预测肺动脉高压的预后。而在治疗开始之后测定的血流动力学指标对预后的价值还未确定。 | 黄洁 叶鹏 Weatherald J Boucly A Chemla D Savale L Peng M Jevnikar M Ja?s X Taniguchi Y O'Connell C Parent F Sattler C Hervé P Simonneau G Montani D Humbert M Adir Y Sitbon O | 2017 | 中华高血压杂志2017，25，11： | 1 |
| 15 | Genetic determination of plasma aldosterone levels in essential hypertension显示文摘 | Luminita P Sylvie G Herve B | 1998 | American Journal of Hypertension1998，11，： | 1 |
| 16 | 查看详情显示文摘 | Fournier M Feumi-Jantou C Rabia C Herve G Launay S | | 0，，： | 1 |
| 17 | Self- consistent 1 - D solution of mulfiquantum - well laser equations 显示文摘 | Debaisieux G Herve G G Filoche M | 1997 | Optical and Quantum Electronics1997，29，6： | 1 |
| 18 | Dodeeatungstosilieie acids:isomers and related heunary compounds 显示文摘 | TEZE A HERVE G | 1990 | Inorg Synth1990，27，： | 1 |
| 19 | Reactive Extrusion: Toward Nanoblends显示文摘 | HU G H HERVE C | | Macromolecules0，32，： | 1 |
| 20 | The influence of site quality,silviculture and region on wood density mixed model in Quereus petraea Liebl显示文摘 | J can-Christophe Hervě Gěrard Nepveu | 2004 | Forest Ecology and Management2004，189，： | 1 |
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