|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Population-based study of DNA image cytometry as screening method for esophageal cancer显示文摘AIM:To explore the DNA image cytometry (DNA-ICM) technique as a primary screening method for esopha-geal squamous precancerous lesions.METHODS:This study was designed as a population-based screening study.A total of 582 local residents aged 40 years-69 years were recruited from Linzhou in Henan and Feicheng in Shandong.However,only 452 subjects had results of liquid-based cytology,DNA-ICM and pathology.The sensitivity and specificity of DNA-ICM were calculated and compared with liquid-based cytology in moderate dysplasia or worse.RESULTS:Sensitivities of DNA-ICM ranging from at least 1 to 4 aneuploid cells were 90.91%,86.36%,79.55% and 77.27%,respectively,which were better than that of liquid-based cytology (75%).Specifici-ties of DNA-ICM were 70.83%,84.07%,92.65% and 96.81%,but the specificity of liquid-based cytology was 91.91%.The sensitivity and specificity of a combination of liquid-based cytology and DNA-ICM were 84.09% and 85.78%,respectively.CONCLUSION:It is possible to use DNA-ICM tech-nique as a primary screening method for esophageal squamous precancerous lesions. | Lin Zhao,Wen-Qiang Wei,Xin-Qing Li,Guo-Qing Wang,Qi Shang,You-Lin Qiao,Department of Cancer Epidemiology,Cancer Institute/Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China De-Li Zhao,Department of Epidemiology,Feicheng People’s Hospital,Feicheng 271600,Shandong Province,China Chang-Qing Hao,Department of Endoscopy,Linzhou Cancer Hospital,Linzhou 456500,Henan Province,China Dong-Mei Lin,Qin-Jing Pan,Department of Pathology,Cancer Institute/Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China Fu-Hua Lei,Department of Pathology,Feicheng People’s Hospi-tal,Feicheng 271600,Shandong Province,China Jin-Wu Wang,Department of Pathology,Linzhou Cancer Hospi-tal,Linzhou 456500,Henan Province,China | 2012 | World Journal of Gastroenterology2012，18，4： | 15 |
| 2 | Cerebral small vessel disease or intracranial large vessel atherosclerosis may carry different risk for future strokes显示文摘Background The effect of cerebral small vessel disease(CSVD)and intracranial arterial stenosis(ICAS)on stroke outcomes remains unclear.Methods Data of 1045 patients with minor stroke or transient ischaemic attack(TIA)were obtained from 45 sites of the Clopidogrel in High-Risk Patients with Acute Non-disabling Cerebrovascular Events(CHANCE)trial.We assessed the associations of burdens of CSVD and ICAS with new strokes and bleeding events using multivariate Cox regression models and those with modified Rankin Scale(mRS)scores using ordinal logistic regression models.Results Among the 1045 patients,CSVD was present in 830 cases(79.4%)and ICAS in 460(44.0%).Patients with>1 ICAS segment showed the highest risk of new strokes(HR 2.03,95%CI 1.15 to 3.56,p=0.01).No association between CSVD and the occurrence of new strokes was found.The presence of severe CSVD(common OR(cOR)2.01,95%CI 1.40 to 2.89,p<0.001)and>1 ICAS segment(cOR 2.15,95%CI 1.57 to 2.93,p<0.001)was associated with higher mRS scores.Severe CSVD(HR 10.70,95%CI 1.16 to 99.04,p=0.04),but not ICAS,was associated with a higher risk of bleeding events.Six-point modified CSVD score improved the predictive power for bleeding events and disability.Interpretation CSVD is associated with more disability and bleeding events,and ICAS is associated with an increased risk of stroke and disability in patients with minor stroke and TIA at 3 months.CSVD and ICAS may represent different vascular pathologies and play distinct roles in stroke outcomes. | Huimin Chen Yuesong Pan Lixia Zong Jing Jing Xia Meng Yuyuan Xu Hongyi Yan Xingquan Zhao Liping Liu Hao Li S Claiborne Johnston Yongjun Wang Yilong Wang | 2020 | Stroke & Vascular Neurology2020，5，2： | 13 |
| 3 | 防护林带:湍流的数学模型与计算机模拟显示文摘虽然防护林用于减小风速、控制热量和水汽传递及污染物扩散、改善气候与环境、增加作物产量等已经有几百年了,但直到近几十年,人们才开始系统地研究防护林空气动力学的遮蔽机制.在本综述中,我们考察了绕防护林带的流动与湍流控制机制,最新的模型与数值模拟研究情况;通过数值模拟与实验数据的比较,来了解防护林带结构与防风效果之间的关系;讨论数值分析如何及为什么能够得到所需要的结果.本文将从多孔隙防护林带流动基本方程组的推导开始,讨论数值模型及模拟过程,对附体与分离流动进行预测;分析了遮蔽机制与动量交换;对风向、防护林密度、宽度和三维性对流动与湍流的影响作了系统的论述.还对热流和土壤水分蒸发的新模型及数值模拟作了简述.最后,我们对网络工作站、群和高性能分布式并行计算机及其对防护林带模型预报能力的提高作了讨论. | WANG Hao Takle Eugene S Shen Jinmei 邵传平 王薇 李家春 | 2003 | 力学进展2003，33，1： | 8 |
| 4 | Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer显示文摘AIM: To compare the clinicopathological features of patients with non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer.METHODS: All the patients with rectosigmoid carcinoma who underwent laparoscopic radical surgical resection in the Shanghai Minimally Invasive Surgical Center at Ruijin Hospital affiliated to Shanghai JiaoTong University between October 2009 and October2013 were included in this study. Twenty-six cases of colonic schistosomiasis diagnosed through colonoscopy and pathological examinations were collected. Symptoms,endoscopic findings and clinicopathological characteristics were evaluated retrospectively.RESULTS: There were no significant differences between patients with and without schistosomiasis in gender, age, CEA, CA19-9, preoperative biopsy findings or postoperative pathology. Patients with rectosigmoid schistosomiasis had a significantly higher CA-125 level and a larger proportion of these patients were at an early tumor stage(P = 0.003). Various morphological characteristics of schistosomiasis combined with rectosigmoid cancer could be found by colonoscopic examination: 46% were fungating mass polyps, 23%were congestive and ulcerative polyps, 23% were cauliflower-like masses, 8% were annular masses.Only 27% of the patients were diagnosed with rectal carcinoma preoperatively after the biopsy. Computed tomography(CT) scans showed thickened intestinal walls combined with linear and tram-track calcifications in 26 patients.CONCLUSION: Rectosigmoid carcinoma combined with schistosomiasis is associated with higher CA-125 values and early tumor stages. CA-125 and CT scans have a reasonable sensitivity for the accurate diagnosis. | Hao Feng Ai-Guo Lu Xue-Wei Zhao Ding-Pei Han Jing-Kun Zhao Lei Shi Tobias S Schiergens Serene ML Lee Wen-Peng Zhang Wolfgang E Thasler | 2015 | World Journal of Gastroenterology2015，21，23： | 6 |
| 5 | Rice monitoring and production estimation using multitemporal RADARSAT显示文摘 | Yun Shao Xiangtao Fan Hao Liu Jianhua Xiao S Ross B Brisco R Brown G Staples | 2001 | Remote Sensing of Environment2001，，3： | 3 |
| 6 | 基于工作地点的分组干预对高血压控制的影响:一项随机临床研究显示文摘基于工作地点的干预可能为一种管理高血压的有效方法。但是目前缺少针对中国工作人群高血压控制情况的研究。本研究旨在评估基于工作地点的多组分别干预策略对改善血压控制的影响。研究设计及受试者:研究者在2013年1月至2014年12月于中国20个城区的60个工作地点进行了一系列高血压管理的随机临床试验。工作地点随机分为干预组(n=40)和对照组(n=20)。每个工作地点的受试者都需要完成一项横断面调查。 | 袁源(摘译) 叶鹏(审校) Wang Z Wang X Shen Y Li S Chen Z Zheng C Kang Y Jiang L Hao G Chang C Gao R | 2020 | 中华高血压杂志2020，28，6： | 3 |
| 7 | Risk for esophageal neoplasia in B arrett’s esophagus patients with mucosal changes indefinite for dysplasia显示文摘 | Bela Horvath Prabhdeep Singh Hao Xie Prashanthi N Thota Daniela S Allende Rish K Pai Deepa T Patil Thomas P Plesec John R Goldblum Xiuli Liu | 2015 | J Gastroenterol Hepatol2015，，： | 2 |
| 8 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 9 | Surface Treatment of Aluminum by High Current Pulsed Electron Beam 显示文摘 | Hao S Z Yao S Guan J | 2001 | Current Applied Physics2001，1，23： | 1 |
| 10 | Electrophoretic motion of a charged spherical particle normal to a planar dielectric wall显示文摘 | Haber S | 1998 | Int J Multiphase Flow1998，24，5： | 1 |
| 11 | Transgene - mediated enkephalin expression at- tenuate signs of naloxone - precipitated morphine withdrawal in rats with neumpathic pain显示文摘 | Hao S Hu J Fink DJ | 2009 | Behav Brain Res2009，197，1： | 1 |
| 12 | Color image segmentation using fuzzy C-mean and eigenspace projections显示文摘 | YANG J F HAO S S CHUNG P C | 2002 | Signal Prooeming2002，82，3： | 1 |
| 13 | Rective power pricing and management显示文摘 | Hao S Y Papalexooulos A | 1997 | IEEE Trans on Power Systems1997，12，1： | 1 |
| 14 | Microstructure and fatigue characteristics of direct chill cast and electromagnetic cast 2024 Al alloy ingots显示文摘 | Kim S W Hao H | 2003 | Metallurgical and Materials Transactions A: Physical Metallurgy and Materials Science2003，34，7： | 1 |
| 15 | An agent-based Web service work- flow model for inter-enterprise collaboration显示文摘 | Wang S Shen W Hao Q | 2006 | Expert Sys- tems with Applications2006，31，4： | 1 |
| 16 | Origin of the Miocene- Pliocene red-earth formation at Xifeng in northern China and implications for paleoenvironments 显示文摘 | Guo Z T Peng S Z Hao Q Z | 2001 | Palaeogeography Palaeoclimatology Palaeoecology2001，170，： | 1 |
| 17 | Vague soft sets and their properties显示文摘 | Xu W Ma J Wang S Hao G | 2010 | Computers and Mathematics with Applications2010，59，： | 1 |
| 18 | Long-term follow-up of mri-guided bilateral anterior capsulotomy in patients with refractory schizophrenia 显示文摘 | Liu W Hao Q Zhan S | 2014 | Stereotact Funct Neurosurg2014，92，3： | 1 |
| 19 | Fingolimod potentiates the effects of sunitinib malate in a rat breast cancer model显示文摘 | Yoanne Mousseau Séverine Mollard Karine Faucher-Durand Laurence Richard Angélique Nizou Jeanne Cook-Moreau Yasser Baaj Hao Qiu Xavier Plainard Laurent Fourcade Benoit Funalot Franck G. Sturtz | 2012 | Breast Cancer Research and Treatment2012，，1： | 1 |
| 20 | Reduction of voltage gated sodium channelprotein in DRG by vector mediated miRNA reduces pain in rats with painful diabetic neuropathy 显示文摘 | Chattopadhyay M Zhou Z Hao S Mata M Fink D J | 2012 | Mol Pain2012，8，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员