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| 1 | Factors predicting adverse short-term outcomes in patients with acute cholangitis undergoing ERCP: A single center experience显示文摘AIM: To identify potential factors that can predict adverse short-term outcomes in patients with acute cholangitis undergoing endoscopic retrograde cholangiopancreatography(ERCP). METHODS: Retrospective analysis of consecutive patients admitted to our center for acute cholangitis and underwent ERCP from 2001 to 2012. Involvement of two or more organ systems was termed as organ failure(OF). Cardiovascular failure was defined based on a systolic blood pressure of < 90 mmHg despite fluid replacement and/or requiring vasopressor treatment; respiratory failure if the Pa02 /Fi02 ratio was < 300 mmHg and/or required mechanical ventilation; coagulopathy if the platelet count was < 80; and renal insufficiency if serum creatinine was > 1.9 mg/dL. Variables associated with short term adverse clinical outcomes defined as persistent OF and/or 30-d mortality was determined. RESULTS: A total of 172 patients(median age 62 years, 56.4% female) were included. The median door to ERCP time was 17 h. Bile duct stones were the most common etiology(n = 67, 39.2%). In multivariate analysis, factors that were independently associated with persistent OF and/or 30-d mortality included American Society of Anesthesiology(ASA) physical classification score > 3(OR = 7.70; 95%CI: 2.73-24.40), presence of systemic inflammatory response syndrome(OR = 3.67; 95%CI: 1.34-10.3) and door to ERCP time greater than 72 h(OR = 3.36; 95%CI: 1.12-10.20). Door to ERCP time greater than 72 h was also associated with 70% increase in the mean length of stay(P < 0.001). Every one point increase in the ASA physical classification and every 1 mg/dL increase in the preERCP bilirubin level was associated with a 34% and 2% increase in the mean length of hospital stay, respectively. Transfer status did not impact clinical outcomes. CONCLUSION: Higher ASA physical classification and delays in ERCP are associated with adverse clinical outcomes and prolonged length of hospital stay in patients with acute cholangitis undergoing ERCP. | Udayakumar Navaneethan Norma G Gutierrez Ramprasad Jegadeesan Preethi GK Venkatesh Madhusudhan R Sanaka John J Vargo Mansour A Parsi | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，3： | 7 |
| 2 | Analysis levels within the SINTAP defect assessment procedures显示文摘 | Ainsworth R A Gutierrez - Solana F Ocejo J R | 2000 | Engineering Fracture Mechanics Volume2000，67，6： | 2 |
| 3 | Effects of vertebrate predation on a caviomorph rodent, the degu (Octodon degus), in a semiarid thorn scrub community of Chile 显示文摘 | Meserve P L Gutierrez J R Jaksic F M | 1993 | Oecologia1993，94，： | 2 |
| 4 | Cytotoxic constituents from daphnia pulex 显示文摘 | Perez Gutierrez R M Lule P R | 2005 | Pharmaceutical Biology2005，43，4： | 1 |
| 5 | Influence of the Prior Austenite Microstructure on the Transformation Products Obtained for C-Mn-Nb Steels显示文摘 | Bengochea R Lopez B Gutierrez I | 1999 | ISIJ International1999，39，6： | 1 |
| 6 | Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro显示文摘 | GARRETT I R CHEN D GUTIERREZ G | 2003 | J Clin Invest2003，111，11： | 1 |
| 7 | E- valuation of oxygen injection as a means of controlling sulfide production in a sewer system 显示文摘 | Gutierrez 0 Mohanakrishnan J Sharma K R | 2008 | Water Res2008，42，17： | 1 |
| 8 | Co-release of glutamate and GABA from single, identified mossy fibre giant boutons 显示文摘 | Beltran JQ Gutierrez R | 2012 | J Physiol2012，590，19： | 1 |
| 9 | High adsorption capacities and two-step adsorption of polar adsorbates on copper benzene-l,3,5-tricarboxylate metal-organic framework 显示文摘 | VAN ASSCHE T R C DUERINCK T GUTIERREZ SEVILLANO J J | 2013 | Journal of Physical Chemistry C2013，117，18： | 1 |
| 10 | Arginine addition in the sta- tionary phase influences the fermentation rate and synthesis of aroma compounds in a synthetic must fermented by three commercial wine strains 显示文摘 | GUTIERREZ A CHIVA R JOSE M G | 2015 | LWT-Food Sei Technol2015，60，2： | 1 |
| 11 | Emergence and evolution of the circadian rhythm of melatonin in children 显示文摘 | Ardura J Gutierrez R Andres J Agapito T | 2003 | Horm Res2003，59，2： | 1 |
| 12 | Mechanical distention modulates alveolar epithelial cell phenotypic expression by transcriptional regulation显示文摘 | Gutierrez JA Ertsey R Seavo LM | 1999 | Am J Respir Cell Mol Biol1999，21，： | 1 |
| 13 | Nitrite effectively inhibits sulfide and methane production in a laboratory scale sewer reactor显示文摘 | Mohanakrishnan J Gutierrez O Meyer R L | 2008 | Water Res2008，42，14： | 1 |
| 14 | 查看详情显示文摘 | H?pfl H Farfán N Castillo D Santillan R Gutierrez A Daran J C | | 0，，： | 1 |
| 15 | NMP 22, BTA stat test and cytology in the diagnosis of bladder cancer: a comparative study 显示文摘 | Gutierrez B JL Rebollo R MH Antolin J FM | 2001 | Urol Int2001，66，4： | 1 |
| 16 | Dry matter production and partitioning in rose (Rosa hybrida) flower shoots显示文摘 | Gutierrez Colomer R P Gonzalez-Real M M Baille A | 2006 | Scientia Horticulturae2006，107，： | 1 |
| 17 | Variation in vegetation and seed bank in Chilean semi-arid community affected by ENSO 1997 显示文摘 | GUTIERREZ J R ARANCIO G JAKSIC F M | 2000 | Joural of Vegetaion Science2000，11，： | 1 |
| 18 | Competitive adsorption of cesium, cobalt and strontium in conditioned clayed soil suspensions显示文摘 | Gutierrez M Fuentes H R | 1991 | Journal of Environmental Radioactivity1991，13，： | 1 |
| 19 | Sauna-induced Rapid Weight Loss Decreases Explosive Power in Women butnot in Men显示文摘 | GUTIERREZ A MESA J L RUIZ J R | 2003 | Int J Sports Med2003，24，7： | 1 |
| 20 | Im- pact of nitrate addition on biofilm properties and activi- ties in rising main sewers 显示文摘 | Mohanakrishnan J Gutierrez O Sharma K R | 2009 | Water Res2009，43，17： | 1 |
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