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4篇 您的检索式:作者名="Guifang Ge"
    题名 作者 年代 出处 被引量
15-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers显示文摘象 5-methylcytosine (5mC ) 和 5-hydroxymethylcytosine (5hmC ) 那样的 DNA 修正是知道在哺乳动物影响全球基因表示的 epigenetic 标记。在人的染色体,与基因表示的靠近的关联和高化学的稳定性给他们的流行,这些 DNA epigenetic 标记能为癌症用作理想的 biomarkers 诊断。利用一种高度敏感、选择的化学标记技术,我们这里报导在传播没有房间的 DNA ( cfDNA )并且在从最近与 colorectal 诊断的 260 个病人的一个队收集的配对的肿瘤和邻近的纸巾的 genomic DNA ( gDNA )的 5hmC 的染色体宽的介绍,胃,胰腺,从 90 个健康个人的肝或甲状腺癌症和正常纸巾。5hmC 主要在与开的染色质和容许的 histone 修正重合的 transcriptionally 活跃的区域被散布。柔韧的联系癌症的 5hmC 签名在 cfDNA 被识别为特定的癌症类型是特征的。传播 cfDNA 的 5hmC 底 biomarkers colorectal 和胃的癌症是高度预兆的并且比常规 biomarkers 优异并且比得上从织物活体检视的 5hmC biomarkers。因此,这新策略能从血样品的分析为癌症的诊断和预后导致有效、最低限度地侵略的方法的发展。Wenshuai Li Xu Zhang Xingyu Lu Lei You Yanqun Song Zhongguang Luo Jun Zhang Ji Nie Wanwei Zheng Diannan Xu Yaping Wang Yuanqiang Dong Shulin Yu Jun Hong Jianping Shi Hankun Hao Fen Luo Luchun Hua Peng Wang Xiaoping Qian Fang Yuan Lianhuan Wei Ming Cui Taiping Zhang Quan Liao Menghua Dai Ziwen Liu Ge Chen Katherine Meckel Sarbani Adhikari Guifang Jia Marc B Bissonnette Xinxiang Zhang Yupei Zhao Wei Zhang Chuan He Jie Liu 2017Cell Research2017,27,10:30
2High flux photocatalytic self-cleaning nanosheet C_(3)N_(4) membrane supported by cellulose nanofibers for dye wastewater purification显示文摘Hazardous dye substances discharged from the textile and dyestuff industries not only threaten local the surrounding ecosystems but are also hard to degraded.We report the preparation of process for a photocatalytic membrane device that can degrade dye pollution under visible light.This filtration membrane,with a well-organized multilayer structure,simultaneously achieves continuous and flow-through separation of degradation products.Cellulose nanofibers(CNFs)were used as a template for nanosheet C_(3)N_(4)(NS C_(3)N_(4))preparation;the performance for the photocatalytic degradation of dyes improved as the morphology changed from bulking to nanosheet.NS C3N4 was then attached to the surface of a prepared CNF membrane via vacuum filtration.This device exhibited high efficiency(the degradation rates of both Rhodamine B and Methylene blue both reached 96%),high flux(above 160 L·h^(-1)·m^(-2)·bar^(-1))and excellent stability(maintaining steady flux and high separation were maintained after 4 h).This easy-preparation,easy-scale-up,and low-cost process provides a new method of fabricating photocatalytic membrane devices for dye wastewater treatment.Lilong Zhang Ge Meng Guifang Fan Keli Chen Yulong Wu Jian Liu 2021Nano Research2021,14,8:3
3Author Correction: 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers显示文摘In the initial published version of this article, there was a mistake in the P value for the correlation between gene-expression changes and 5 hmC changes in tumors. The correct P value should be same as the P value shown in Fig. S6A: 9.8?×?10?6 (mistakenly shown as “9.8?×?106” in the main text). This correction does not affect the description of results or the conclusions of this study, since the range of P value is between 0 and 1.Wenshuai Li Xu Zhang Xingyu Lu Lei You Yanqun Song Zhongguang Luo Jun Zhang Ji Nie Wanwei Zheng Diannan Xu Yaping Wang Yuanqiang Dong Shulin Yu Jun Hong Jianping Shi Hankun Hao Fen Luo Luchun Hua Peng Wang Xiaoping Qian Fang Yuan Lianhuan Wei Ming Cui Taiping Zhang Quan Liao Menghua Dai Ziwen Liu Ge Chen Katherine Meckel Sarbani Adhikari Guifang Jia Marc B Bissonnette Xinxiang Zhang Yupei Zhao Wei Zhang Chuan He Jie Liu 2019Cell Research2019,29,7:1
4An efficient nanodiamond-based monolithic foam catalyst prepared by a facile thermal impregnation strategy for direct dehydrogenation of ethylbenzene to styrene显示文摘Nanodiamond(ND)has long been recognized as an effective carbocatalyst for synthesizing styrene via direct dehydrogenation(DDH).However,the induced drastic pressure drop of its powder form limits its industrial application in heterogeneous catalytic process.In this work,we report a facile hexamethylenetetramine nitrate(HN)-assisted thermal impregnation(HNTI)strategy for fabricating a novel nanodiamondbased monolithic foam(ND/CNT-SiC-ms-HN)catalyst through a two-step approach:One is to soak the carbon nanotube-modified Si C foam(CNT-SiC)with the slurry composed of HN,KCl,Li Cl,and dispersed ND,and the other is to heat the slurry-soaked CNT-SiC(ND-HN-KCl-Li Cl/CNT-SiC)in N_(2) atmosphere at750℃.The as-synthesized ND/CNT-SiC-ms-HN monolithic foam features the enriched surface kenotic C=O by promoted ND dispersion and O-doping,abundant stuctural defects,and improved nucleophilicity by N-doping,originating from the promoted ND dispersion by thermal impregnation(TI)in KCl-LiCl molten salt(MS)and the presence of HN in the annealing process.As a result,the ND/CNT-Si C-ms-HN monolithic foam catalyst by HNTI strategy exhibits 1.5 folds higher steady-state styrene rate(5.49 mmol g^(-1)h^(-1))associated with 98.4%of styrene selectivity compared to the ND-based monolithic foam catalyst(ND/CNT-SiC).Moreover,the ND/CNT-Si C-ms-HN monolithic foam shows excellent long-term stability for the direct dehydrogenation of ethylbenzene to styrene.This work also comes up with a novel way of preparing other highly-dispersed nanocarbons-based monolithic foam catalysts with promising catalytic performance for diverse transformations.Guifang Ge Xiaojing Wei Hongchen Guo Zhongkui Zhao 2023Chinese Chemical Letters2023,34,5:0
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