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| 1 | Efficacy and safety of pegylated-interferon α-2a in hemodialysis patients with chronic hepatitis C显示文摘AIM: To evaluate the efficacy and safety of pegylated-interferon alpha-2a in hemodialysis patients with chronichepatitis C.METHODS: Thirty-six hemodialysis patients with chronichepatitis C were enrolled in a controlled and prospectivestudy. All patients were treatment naive, positivetested for anti-HCV antibodies, and positive tested forserum HCV-RNA. Twenty-two patients received 135 μgpeglyated-interferon a-2a weekly for 48 wk (group A).The remaining patients were left untreated, elevenrefused therapy, and three were not candidates forkidney transplantation and were allocated to the controlgroup (group B). At the end of the treatment biochemicaland virological response was evaluated, and 24 wk aftercompletetion of therapy sustained virological response(SVR) was assessed. Side effects were monitored.RESULTS: Of 22 hemodialysis patients, 12 were maleand 10 female, with a mean age of 35.2 ± 12.1 years.Virological end-of-treatment response was observed in14 patients (82.4%) in group A and in one patient (7.1%)in group B (P = 0.001). Sustained virological responsewas observed in 11 patients (64.7%) in group A and inone patient in group B (7.1%). Biochemical responseparameters normalized in 10/14 patients (71.4%) at theend of the treatment. ALT levels in group B were initiallyhigh in six patients and normalized in one of them (25%)at the end of the 48 wk. In five patients (22.7%) therapyhad to be stopped at mo 4 due to complications ofweakness, anemia, and bleeding.CONCLUSION: SVR could be achieved in 64.7% ofpatients on hemodialysis with chronic hepatitis C by atreatment with peglyated-interferon a-2a. Group A hada significantly better efficacy compared to the controlgroup B, but the side effects need to be concerned. | Celal Ayaz Mustafa Kemal Celen Ugur Nedim Yuce Mehmet Faruk Geyik | 2008 | World Journal of Gastroenterology2008，14，2： | 5 |
| 2 | Inhibition of respiration and distri-bution of Cd,Pb,Hg,Ag and Cr species in a nitrifying sludge显示文摘 | Cecen F Semerci N Geyik A G | 2010 | Journal of Hazardous Materials2010，178，1： | 1 |
| 3 | Serum level of lipoprotein (a) is inversely associated with the development of coronary collateral circulation 显示文摘 | Aras D Geyik B Topaloglu S | 2006 | Coron Artery Dis2006，17，2： | 1 |
| 4 | Serum level of lipoprotein (a) is inversely associated with the development of coronary collateral circulation显示文摘 | Dursun Aras Bilal Geyik Serkan Topaloglu Kumral Ergun Selime Ayaz Orhan Maden Ali Yildiz Mustafa Balci Ozcan Ozeke Sule Korkmaz | 2006 | Coronary Artery Disease2006，，2： | 1 |
| 5 | Venous thromboembolism after retrieval of inferior vena cava filters显示文摘 | Yavuz K Geyik S Hoppe H | 2008 | J Vasc Interv Radiol2008，19，4： | 1 |
| 6 | Radiofrequency ablation of unresectable hepatic tumors 显示文摘 | Geyik S Akhan O Abbasoglu O | 2006 | Diagn Interv Radiol2006，12，4： | 1 |
| 7 | Effects of octreotide acetate and saccharomyces boulardii on bacterial translocation in an experimental intestinal loop obstruction model of rats显示文摘 | Aldemir M Kokoglu O F Geyik M F | 2002 | Tohoku J Exp Med2002，198，1： | 1 |
| 8 | Effect of erythmpoietin on brain tissue after experimental head trauma in rats 显示文摘 | Akdemir Ozisik P Omckaptan H Ozdemir Geyik P | 2007 | Surg Neural2007，68，5： | 1 |
| 9 | Clinical and laboratory features of brucellosis in two university hospitals in southeast Turkey显示文摘 | Kokoglu O F Hosoglu S Geyik M F | 2006 | Trop Doct2006，36，： | 1 |
| 10 | Epidemiology of burn unitinfections in children显示文摘 | Geyik MF Aldemir M Hosuglu S | 2003 | Am J Infect Control2003，31，6： | 1 |
| 11 | H-FABP in the early diagnosis of stroke 显示文摘 | Onur Akpnar Srma Geyik Ay a Akaln | 2009 | Chinese Journal of Neuro- logy2009，11，256： | 1 |
| 12 | The effects of Saccharomyces 5oulardii on bac terial translocation in rats with obstructive jaundice显示文摘 | Geyik M F Aldemir M Hosoglu S Ayaz C Satilmis S Buyuk bayram H | 2006 | Ann R Coll Surg Engl2006，88，： | 1 |
| 13 | Biologically inspired self selective routing with preferred path selection显示文摘 | Szymanski B K Morrell C Geyik S C | 2008 | Lecture Notes in Computer Science2008，5151，： | 1 |
| 14 | Endovaacular treatment of brain ar- teriovenous malformations with prolonged intranidal Onyx injec- tion technique: long-term results in 350 consecutive patients with completed endovascular Ireatment course 显示文摘 | Saatci I Geyik S Yavuz K | 2011 | J Neurosurg2011，115，1： | 1 |
| 15 | Polymyositis complicated with complete atrioventrieular block:A case report and review of the literature显示文摘 | Alyan O Ozdemir O Geyik B | 2003 | Angiology2003，54，6： | 1 |
| 16 | Predictability of retroperitoneal lymph node metastasis by using clinicopathologic variables in surgically staged endometrial cancer 显示文摘 | Taskiran C Yuce K Geyik PO | 2006 | Int J Gynecol Cancer2006，16，： | 1 |
| 17 | Tuberculous meningitis in adults: an eleven-year review显示文摘 | Hosoglu S Ayaz C Geyik MF | 1998 | Int J Tuberc Lung Dis1998，2，7： | 1 |
| 18 | Time distribution of seizures during long-term video-EEG monitoring显示文摘 | Dericioglu N Karatas H Geyik PO | 2003 | Clin Electroencephal2003，34，4： | 1 |
| 19 | Comparison of bioactive coils and bare platinum coils for treatment of intracranial aneurysms:a matched-pair analysis显示文摘 | Geyik S Ertugrul O Yavuz K | | 0，，： | 1 |
| 20 | H-FABP in the early diagnosis of stroke显示文摘 | Akpinar O Geyik S Acikalin A et aI | 2009 | J Neurol2009，256，11： | 1 |
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