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| 1 | A new pancreaticojejunostomy technique: A battle against postoperative pancreatic fistula显示文摘AIM:To present a new technique of end-to-side, ductto-mucosa pancreaticojejunostomy with seromuscular jejunal flap formation, and insertion of a silicone stent. METHODS:We present an end-to-side, duct-to-mucosa pancreaticojejunostomy with seromuscular jejunal flap formation, and the insertion of a silicone stent. This technique was performed in thirty-two consecutive patients who underwent a pancreaticoduodenectomy procedure by the same surgical team, from January 2005 to March 2011. The surgical procedure performed in all cases was classic pancreaticoduodenectomy, without preservation of the pylorus. The diagnosis of pancreatic leakage was defined as a drain output of any measurable volume of fluid on or after postoperative day 3 with an amylase concentration greater than three times the serum amylase activity. RESULTS:There were 32 patients who underwent end-to-side, duct-to-mucosa pancreaticojejunostomy with seromuscular jejunal flap formation. Thirteen of them were women and 19 were men. These data correspond to 40.6% and 59.4%, respectively. The mean age was 64.2 years, ranging from 55 to 82 years. The mean operative time was 310.2 ± 40.0 min, and was defined as the time period from the intubation up to the extubation of the patient. Also, the mean time needed to perform the pancreaticojejunostomy was 22.7 min, ranging from 18 to 25 min. Postoperatively, one patient developed a low output pancreatic fistula, three patients developed surgical site infection, and one patient developed pneumonia. The rate of overall morbidity was 15.6%. There was no 30-d postoperative mortality. CONCLUSION:This modification appears to be a significantly safe approach to the pancreaticojejunostomy without adversely affecting operative time. | Stylianos Katsaragakis Andreas Larentzakis Sotirios-Georgios Panousopoulos Konstantinos G Toutouzas Dimitrios Theodorou Spyridon Stergiopoulos Georgios Androulakis | 2013 | World Journal of Gastroenterology2013，19，27： | 12 |
| 2 | Implant retention after acute and hematogenous periprosthetic hip and knee infections: Whom, when and how?显示文摘Periprosthetic joint infections(PJI) of the hip and the knee are grossly classified as early post-operative, acute hematogenous and late chronic infections. Whereas two-stage exchange arthroplasty is the standard of care in North America for treating chronic infections, irrigation and debridement(I and D) with retention of implants has been used in an attempt to treat the other two types of PJIs. The rationale of this approach is that a PJI may be eradicated without the need of explanting the prostheses, as long as it has not transitioned into a chronic state. With the present paper, we review current evidence regarding the role of I and D with implant retention for treating PJIs of the hip and the knee. While a very wide range of success rates is reported in different studies, a short period of time between initiation of symptoms and intervention seems to play a prominent role with regards to a successful outcome. Moreover, pathogens of higher virulence and resistance to antibiotics are associated with a poorer result. Specific comorbidities have been also correlated with a less favorable outcome. Finally, one should proceed with serial I and Ds only under the condition that a predefined,aggressive protocol is applied. In conclusion,when treating a PJI of the hip or the knee, all the above factors should be considered in order to decide whether the patient is likely to benefit from this approach. | Georgios K Triantafyllopoulos Vasileios Soranoglou Stavros G Memtsoudis Lazaros A Poultsides | 2016 | World Journal of Orthopedics2016，7，9： | 7 |
| 3 | Acute upper gastrointestinal bleeding in patients on long-term oral anticoagulation therapy: Endoscopic findings, clinical management and outcome显示文摘AIM: Acute gastrointestinal bleeding is a severe complication in patients receiving long-term oral anticoagulant therapy.The purpose of this study was to describe the causes and clinical outcome of these patients.METHODS: From January 1999 to October 2003, 111patients with acute upper gastrointestinal bleeding (AUGIB)were hospitalized while on oral anticoagulants. The causes and clinical outcome of these patients were compared with those of 604 patients hospitalized during 2000-2001with AUGIB who were not taking warfarin.RESULTS: The most common cause of bleeding was peptic ulcer in 51 patients (45%) receiving anticoagulants compared to 359/604 (59.4%) patients not receiving warfarin (P<0.05). No identifiable source of bleeding could be found in 33 patients (29.7%) compared to 31/604(5.1%) patients not receiving anticoagulants (P= 0.0001).The majority of patients with concurrent use of non-steroidal anti-inflammatory drugs (NSATDs) (26/35, 74.3%) had a peptic ulcer as a cause of bleeding while 32/76 (40.8%)patients not taking a great dose of NSATDs had a negative upper and lower gastrointestinal endoscopy. Endoscopic hemostasis was applied and no complication was reported.Six patients (5.4%) were operated due to continuing or recurrent hemorrhage, compared to 23/604 (3.8%) patients not receiving anticoagulants. Four patients died, the overall mortality was 3.6% in patients with AUGIB due to anticoagulants, which was not different from that in patients not receiving anticoagulant therapy.CONCLUSION: Patients with AUGIB while on long-term anticoagulant therapy had a clinical outcome, which is not different from that of patients not taking anticoagulants.Early endoscopy is important for the management of these patients and endoscopic hemostasis can be safely applied. | Konstantinos C Thomopoulos Konstantinos P Mimidis George J Theocharis Anthie G Gatopoulou Georgios N Kartalis Vassiliki N Nikolopoulou | 2005 | World Journal of Gastroenterology2005，11，9： | 5 |
| 4 | COVID-19 and liver injury: An ongoing challenge显示文摘The new coronavirus severe acute respiratory syndrome coronavirus 2(SARSCoV-2)was identified in December 2019,in Wuhan,China.The virus was rapidly spread worldwide,causing coronavirus disease 2019(COVID-19)pandemic.Although COVID-19 is presented,usually,with typical respiratory symptoms(i.e.,dyspnea,cough)and fever,extrapulmonary manifestations are also encountered.Liver injury is a common feature in patients with COVID-19 and ranges from mild and temporary elevation of liver enzymes to severe liver injury and,even,acute liver failure.The pathogenesis of liver damage is not clearly defined;multiple mechanisms contribute to liver disorder,including direct cytopathic viral effect,cytokine storm and immune-mediated hepatitis,hypoxic injury,and druginduced liver toxicity.Patients with underlying chronic liver disease(i.e.,cirrhosis,non-alcoholic fatty liver disease,alcohol-related liver disease,hepatocellular carcinoma,etc.)may have greater risk to develop both severe COVID-19 and further liver deterioration,and,as a consequence,certain issues should be considered during disease management.The aim of this review is to present the prevalence,clinical manifestation and pathophysiological mechanisms of liver injury in patients with SARS-CoV-2 infection.Moreover,we overview the association between chronic liver disease and SARS-CoV-2 infection and we briefly discuss the management of liver injury during COVID-19. | Ioanna Papagiouvanni Serafeim-Chrysovalantis Kotoulas Athanasia Pataka Dionisios G Spyratos Konstantinos Porpodis Afroditi K Boutou Georgios Papagiouvannis Ioanna Grigoriou Christos Vettas Ioannis Goulis | 2023 | World Journal of Gastroenterology2023，29，2： | 2 |
| 5 | Severe infection with multidrug-resistant Salmonella choleraesuis in a young patient with primary sclerosing cholangitis显示文摘Massive global spread of multidrug-resistant(MDR) Salmonella spp. expressing extended-spectrum beta-lactamase(ESBL) and additional resistance to fluoroquinolones has often been attributed to high international mobility as well as excessive use of oral antibiotics in livestock farming. However, MDR Salmonella spp. have not been mentioned as a widespread pathogen in clinical settings so far. We demonstrate the case of a 25-year-old male with primary sclerosing cholangitis who tested positive for MDR Salmonella enterica serotype Choleraesuis expressing ESBL and fluoroquinolone resistance. The pathogen was supposedly acquired during a trip to Thailand, causing severe fever, cholangitis andpancreatitis. To our knowledge, this is the first report of Salmonella enterica serotype Choleraesuis in Europe expressing such a multidrug resistance pattern. ESBL resistance of Salmonella enterica spp. should be considered in patients with obstructive biliary tract pathology and travel history in endemic countries. | Philip G Ferstl Claudia Reinheimer Katalin Jozsa Stefan Zeuzem Volkhard AJ Kempf Oliver Waidmann Georgios Grammatikos | 2017 | World Journal of Gastroenterology2017，23，11： | 2 |
| 6 | Early stent thrombosis secondary to food allergic reaction:Kounis syndrome following rice pudding ingestion显示文摘Kounis syndrome is the concurrence of coronary spasm, acute myocardial infarction or stent thrombosis, with allergic reactions in the setting of mast-cell and platelet activation. In this report Kounis syndrome manifesting as stent thrombosis with left ventricular thrombus formation was triggered by a food-induced allergic reaction. The allergic reaction to food was confirmed by oral rice pudding ingredients challenge test while skin tests were inconclusive. To our knowledge, this is first report of early stent thrombosis secondary to food allergic reaction in a 70-year-old man patient who was found to have left ventricular thrombus and undiagnosed hypertrophic cardiomyopathy. | Georgios Tzanis Maria Bonou Nikolaos Mikos Smaragda Biliou Ioanna Koniari Nicholas G Kounis John Barbetseas | 2017 | World Journal of Cardiology2017，9，3： | 2 |
| 7 | A two dimensional numerical study of the stick-slip extrusion instability显示文摘 | ELENI T GEORGIOS C G ANDREAS N A | 2007 | J Non-Newton Fluid Mech2007，146，： | 1 |
| 8 | Power control for cooperative dynamic spectrum access networks with diverse QoS Constraints 显示文摘 | Nikolaos Gatsis Antonio G Marques Giannakis Georgios B | 2010 | IEEE transactions on communications2010，58，3： | 1 |
| 9 | Axial capacity of circularconcrete-filled-tube columns显示文摘 | Georgios G Dennis L | 2004 | Journal ofConstructional Steel Research2004，60，： | 1 |
| 10 | Incorporated evaporative condenser 显示文摘 | Michalis G V Andronikos E F Georgios T K | 2007 | Applied Thermal Eng2007，27，56： | 1 |
| 11 | Cross-layer Combining of Adaptive Modulation and Coding with Truncated ARQ over Wireless Links 显示文摘 | Liu Qing-wen Zhou Sheng-li Georgios B G | 2004 | IEEE Transactions on Wireless Communications2004，3，5： | 1 |
| 12 | Recent Advances in High- Voltage Direct- Current Power Transmission Systems 显示文摘 | Agelidis Vassilios G Demetriades Georgios D Flourentzou Nikolas | 2006 | 206 - 2132006，，： | 1 |
| 13 | Queuing with Adaptive Modulation and Coding over Wireless Links:Cross-layer Analysis and Design 显示文摘 | Liu Qing-Wen Zhou Sheng-Li Georgios B G | 2005 | IEEE Transactions on Wireless Communications2005，4，3： | 1 |
| 14 | Statistical Tests for Presence of Cyclostationary 显示文摘 | Amod V D Georgios B G | 1994 | IEEE Transactions on signal pro- cessing1994，42，9： | 1 |
| 15 | Analyzing and Optimizing Adaptive Modulation Coding Jointly with ARQ for QoS- guaranteed Traffic 显示文摘 | Liu Xin-wang Liu Qing-wen Georgios B G | 2007 | IEEE Transactions on Vehicular Technology2007，56，2： | 1 |
| 16 | A study of various factors affecting Newtonian extrudate swell显示文摘 | Mitsoulis E Georgios G C Kountouriotis Z | 2012 | Comput Fluids2012，57，4： | 1 |
| 17 | The rat adequately reflects human responses to exercise in blood biochemi- cal profile : a comparative study 显示文摘 | GEORGIOS G AIKATERINI T ANTONIOS K | 2015 | Physiological Reports2015，3，2： | 1 |
| 18 | Modeling the thermal destruction of toluene (C7H8) as tar-related species for fuel gas cleanup显示文摘 | Taralas Georgios Kontominas Michael G Kakatsios Xenophon | 2003 | Energy & Fuels2003，17，2： | 1 |
| 19 | Modeling the hermal destruction of toluene (C7 H8)as tar-related species for fuel gas cleanup显示文摘 | Georgios Taralas Michael G Kontominas | 2003 | Energy & Fuel2003，17，： | 1 |
| 20 | CYP1A1,CYP19,and GSTM1 polymorphisms increase the risk of endometriosis显示文摘 | DEMETRIOS A A GEORGIOS E K ANASTASIA G G | 2003 | Fertil Steril2003，79，1： | 1 |
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