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| 1 | Ultrahigh performance concrete–properties, applications and perspectives显示文摘Over the last twenty years,remarkable advances have taken place in the research and application of ultra-high performance concrete(UHPC),which exhibits outstanding mechanical properties and excellent durability.It has shown great potential for the next generation infrastructure construction from the sustainability point of view.This paper will give an overview on UHPC,with particular focus on the properties,applications and perspectives.After several decades of development,several types of commercial UHPC materials are available in the market,and the properties of UHPC have been characterized by numerous experimental and field tests.Generally speaking,the performance(e.g.mechanical properties and durability)of UHPC is much better than normal concrete(NC)and high performance concrete(HPC).Therefore,the uses of UHPC are growing all over the world,in both fields of new construction and retrofitting.Nevertheless,it is still a special material and technology,which is not worldwide accepted.So some application prospects of UHPC are briefly introduced in the paper,and the efforts,which have to be made to turn UHPC into a widespread‘regular’technology,are discussed.This paper aims to help designers,engineers,architects and infrastructure owners to know the capacities of UHPC and thus to increase the applications of this material. | GU Chun Ping YE Guang SUN Wei | 2015 | Science China(Technological Sciences)2015，58，4： | 28 |
| 2 | Cadmium Activates Reactive Oxygen Species-dependent AKT/mT OR and Mitochondrial Apoptotic Pathways in Neuronal Cells显示文摘Objective To examine the role of Cd-induced reactive oxygen species(ROS)generation in the apoptosis of neuronal cells.Methods Neuronal cells(primary rat cerebral cortical neurons and PC12 cells)were incubated with or without Cd post-pretreatment with rapamycin(Rap)or N-acetyl-L-cysteine(NAC).Cell viability was determined by MTT assay,apoptosis was examined using flow cytometry and fluorescence microscopy,and the activation of phosphoinositide 3'-kinase/protein kinase B(Akt)/mammalian target of rapamycin(m TOR)and mitochondrial apoptotic pathways were measured by western blotting or immunofluorescence assays.Results Cd-induced activation of Akt/m TOR signaling,including Akt,m TOR,p70 S6 kinase(p70 S6K),and eukaryotic initiation factor 4E binding protein 1(4E-BP1).Rap,an m TOR inhibitor and NAC,a ROS scavenger,blocked Cd-induced activation of Akt/m TOR signaling and apoptosis of neuronal cells.Furthermore,NAC blocked the decrease of B-cell lymphoma 2/Bcl-2 associated X protein(Bcl-2/Bax)ratio,release of cytochrome c,cleavage of caspase-3 and poly(ADP-ribose)polymerase(PARP),and nuclear translocation of apoptosis-inducing factor(AIF)and endonuclease G(Endo G).Conclusion Cd-induced ROS generation activates Akt/m TOR and mitochondrial pathways,leading to apoptosis of neuronal cells.Our findings suggest that m TOR inhibitors or antioxidants have potential for preventing Cd-induced neurodegenerative diseases. | YUAN Yan WANG Yi HU Fei Fei JIANG Chen Yang ZHANG Ya Jing YANG Jin Long ZHAO Shi Wen GU Jian Hong LIU Xue Zhong BIAN Jian Chun LIU Zong Ping | 2016 | Biomedical and Environmental Sciences2016，29，2： | 8 |
| 3 | Effect of Cadmium on Rat Leydig Cell Testosterone Production and DNA Integrity in vitro显示文摘Cadmium(Cd)is an elemental heavy metal with widely recognized toxicity.Its long-term use in industrial processes and daily activities has caused alarming levels of Cd contamination in the natural environment.According to the estimates by the Agency of Toxic Substances and Disease Registry in the US,25 000 to 30 000 metric tons of Cd is annually released to the environment[1].Results of previous studies have demonstrated that several organs are targets of Cd,but the most important of these targeted organs may be the testes.Cadmium can cause the apoptosis of testis cells and modify | LIU Qing GU Jian Hong YUAN Yan LIU Xue Zhong WANG Ya Jun WANG Han Dong LIU Zong Ping WANG Zong Yuan BIAN Jian Chun | 2013 | Biomedical and Environmental Sciences2013，26，9： | 3 |
| 4 | Ultralarge Rabi splitting and broadband strong coupling in a spherical hyperbolic metamaterial cavity显示文摘Strong coupling(SC) between two resonant plasmon modes can result in the formation of new hybrid modes exhibiting Rabi splitting with strong energy exchange at the nanoscale. However, normal Rabi splitting is often limited to ~50–320 me V due to the short lifetime of the plasmon mode. Here, we theoretically demonstrate a record Rabi splitting energy as large as 805 me V arising from the SC between the high-Q plasmonic whispering gallery mode and high-Q cavity plasmon resonance supported by a spherical hyperbolic metamaterial cavity,which consists of a dielectric nanosphere core wrapped in 7 alternating layers of silver/dielectric materials.In addition, the new hybrid modes formed by the SC are shown to exhibit an extralong lifetime of up to 71.9–81.6 fs, with the large electric field intensity enhancement at both the dielectric core and the dielectric layers. More importantly, the spectral ranges of SC can be tuned across an ultrabroad range from the visible to the near-IR by simply changing the dielectric core size. These findings may have potential applications in bright single-photon sources. | PING GU JING CHEN SIYU CHEN CHUN YANG ZUXING ZHANG WEI DU ZHENGDONG YAN CHAOJUN TANG ZHUO CHEN | 2021 | Photonics Research2021，9，5： | 2 |
| 5 | Measurement of Br(n,γ)cross sections up to stellar s-process temperatures at the CSNS Back‑n显示文摘The neutron capture cross sections(n,γ)of bromine were obtained using the time-of-flight technique at the Back-n facility of the China Spallation Neutron Source.Promptγ-rays originating from neutron-induced capture events were detected using four C_(6)D_(6) detectors.The pulse-height weighting technique and double-bunch unfolding method based on Bayesian theory were used in the data analysis.Background deductions,normalization,and corrections were carefully considered to obtain reliable measurement results.The multilevel R-matrix Bayesian code SAMMY was used to extract the resonance parameters in the resolved resonance region(RRR).The average cross sections in the unresolved resonance region(URR)were obtained from 10 to 400 keV.The experimental results were compared with data from several evaluated libraries and previous experi-ments in the RRR and URR.The TALYS code was used to describe the average cross sections in the URR.The astrophysical Maxwell average cross sections(MACSs)of ^(79,81)Br from kT=5 to 100 keV were calculated over a sufficiently wide range of neutron energies.At a thermal energy of kT=30 keV,the MACS value for ^(79)Br 682±68 mb was in good agreement with the KADoNiS v1.0 recommended value.By contrast,the value of 293±29 mb for ^(81)Br was substantially higher than that of the evaluated database and the KADoNiS v1.0 recommended value. | Gao‑Le Yang Zhen‑Dong An Wei Jiang Xian‑Kai Li Wei‑Wei Qiu Zheng‑Fa Liao Zi‑Yue Zhuang Xiao‑Ping Zhang Sheng‑Li Chen Chen‑Chen Guo Er‑Xi Xiao Xiao Fang Xin‑Xiang Li Xin‑Rong Hu Bing Jiang Jin‑Cheng Wang Jie Ren Wen Luo Zhi‑Chao Zhu Hao‑Yang Lan Zong‑Wei Cao Xu Ma Ying‑Du Liu Pu‑Sen Wang Yi Yang Ping Su Xian‑Gai Deng Wan‑Bing He Chun‑Wang Ma Yu‑Ting Wang Zhi‑Tao Dai Peng‑Qin He Ren‑Guang Tang Tao Zhou Jing Wang Han Yi Yue Zhang Yong‑Hao Chen Rui‑Rui Fan Ke‑Qing Gao Qiang Li Kang Sun Zhi‑Xin Tan Min‑Hao Gu Han‑Tao Jing Jing‑Yu Tang | 2023 | Nuclear Science and Techniques2023，34，11： | 0 |
| 6 | Application of Nanogoid Probe Coupled with Silver Enhancement in Rapid cTnI Colorimetric Immunoassay显示文摘A rapid, inexpensive, reliable, and flexible quantitative immunoassay for cardiac troponin I (cTnI) based on the concepts of one-step dual monoclonal antibody “sandwich” principle. The low density protein array, the nanogold probe, and the silver enhancement on the gold particle were provided. The whole detection procedure of the assay could be fulfilled within 40 min with the pretreated colloidal gold-labeled detection antibody and supporting substrate. The assay showed good specific response to cTnI with very low cross-reactivity ratio to the skeletal isoforms of troponin I (sTnI), cardiac troponin T (cTnT), and myoglobin. 588 serum samples were assayed simultaneously by enzyme-linked immuno sorbent assay (ELISA) and this colloidal gold method to test the validity of the method and the data were analyzed using the statistical package SPSS version 11.0 (SPSS Inc.). There was no significant difference between these two assays (P=0.66>0.05). The agreement between this method (≥ or <0.3 ngmL) and ELISA was 86%. | Nong Yue HE Hui Shi GUO Di YANG Chun Rong GU Zhi Ping BIAN Wen Hui WAN Ji Nan ZHANG | 2005 | Chinese Chemical Letters2005，16，12： | 0 |
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