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Effect of Cadmium on Rat Leydig Cell Testosterone Production and DNA Integrity in vitro

查看全文 作  者:LIU [1,2]Qing;GU Jian [1,2]Hong;YUAN [1,2]Yan;LIU Xue [1,2]Zhong;WANG Ya [1,2]Jun;WANG Han [1,2]Dong;LIU Zong [1,2]Ping;WANG Zong [1,2]Yuan;BIAN Jian [1,2]Chun 高影响力作者 机构地区:[1]Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses;[2]Department of Veterinary clinical Medicine, Veterinary Medicine College, Yangzhou University高影响力机构 出  处:《Biomedical and Environmental Sciences》索引2013年第26卷第9期,共5页高影响力期刊 基  金:supported by the Natural Science Foundation of the Higher Education Institutions of Jiangsu Province,China(No.08KJD230002);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD) 摘  要:Cadmium(Cd)is an elemental heavy metal with widely recognized toxicity.Its long-term use in industrial processes and daily activities has caused alarming levels of Cd contamination in the natural environment.According to the estimates by the Agency of Toxic Substances and Disease Registry in the US,25 000 to 30 000 metric tons of Cd is annually released to the environment[1].Results of previous studies have demonstrated that several organs are targets of Cd,but the most important of these targeted organs may be the testes.Cadmium can cause the apoptosis of testis cells and modify 关 键 词:镉(Cd) 细胞分泌 睾丸 DNA 整性 睾酮 间质 大鼠
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