|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Intracellular tat of human immunodeficiency virus type 1 activates lytic cycle replication of Kaposi's sarcoma-associated herpesvirus. Role of JAK/STAT signaling显示文摘 | Zeng, Y. Zhang, X. H. Huang, Z. Cheng, L. Yao, S. H. Qin, D. Chen, X. Y. Tang, Q. Lv, Z. G. Zhang, L. Lu, C. | 2007 | 南京医科大学学报(自然科学版)2007，27，5： | 31 |
| 2 | Aquaporin-4 deficiency down-regulates glutamate uptake and GLT-1 expression in astrocytes显示文摘 | Zeng, X. N. Sun, X. L. Gao, L. Fan, Y. Ding, J. H. Hu, G. | 2007 | 南京医科大学学报(自然科学版)2007，27，5： | 20 |
| 3 | Mapping Sea Level Rise Behavior in an Estuarine Delta System:A Case Study along the Shanghai Coast显示文摘 | H.Q. Cheng J.Y. Chen Z.J. Chen R.L. Ruan G.Q. Xu G. Zeng J.R. Zhu Z.J. Dai X.Y. Chen S.H. Gu X.L. Zhang H.M. Wang | 2018 | Engineering2018，4，1： | 11 |
| 4 | K-ATP channel openers facilitate glutamate uptake by GluTs in rat primary cultured Astrocytes显示文摘Increasing evidence, including from our laboratory, has revealed that opening of ATP sensitive potassium channels(K-ATP channels) plays the neuronal protective roles both in vivo and in vitro. Thus K-ATP channel openers(KCOs) have been proposed as potential neuroprotectants. Our previous studies demonstrated that K-ATP channels could regulate glutamate uptake activity in PC12 cells as well as in synaptosomes of rats. Since glutamate transporters(GluTs) of astrocytes play crucial roles in glutamate uptake and KATP channels are also expressed in astrocytes, the present study showed whether and how KATP channels regulated the function of GluTs in primary cultured astrocytes. The results showed that nonselective KCO pinacidil, selective mitochondrial KCO diazoxide, novel, and blood-brain barrier permeable KCO iptakalim could enhance glutamate uptake, except for the sarcolemmal KCO P1075. Moreover pinacidil, diazoxide, and iptakalim reversed the inhibition of glutamate uptake induced by 1-methyl-4-phenylpyridinium(MPP+). These potentiated effects were completely abolished by mitochondrial K-ATP blocker 5-hydroxydecanoate. Furthermore, either diazoxide or iptakalim could inhibit MPP+-induced elevation of reactive oxygen species (ROS) and phosphorylation of protein kinases C(PKC). These findings are the first to demonstrate that activation of K-ATP channel, especially mitochondrial K-ATP channel, improves the function of GluTs in astrocytes due to reducing ROS production and downregulating PKC phosphorylation. Therefore, the present study not only reveals a novel pharmacological profile of KCOs as regulators of GluTs, but also provides a new strategy for neuroprotection. | Sun, X. L. Zeng, X. N. Zhou, F. Dai, C. P. Ding, J. H. Hu, G. Nanjing Med Univ,Dept Anat Histol & Pharmacol,Neuropharmacol Lab,Nanjing 210029,Jiangsu,Peoples R China. | 2008 | 南京医科大学学报(自然科学版)2008，28，6： | 7 |
| 5 | Two broad-spectrum blast resistance genes, Pi9(t) and Pi2(t), are physically linked on rice chromosome 6显示文摘 | G. Liu G. Lu L. Zeng G.-L. Wang | 2002 | Molecular Genetics and Genomics2002，，4： | 4 |
| 6 | Seasonal trends in PM2.5 source contributions in Beijing, China显示文摘 | Mei Zheng Lynn G. Salmon James J. Schauer Limin Zeng C.S. Kiang Yuanhang Zhang Glen R. Cass | 2005 | Atmospheric Environment2005，，22： | 3 |
| 7 | Molecular co-expression of the c-Met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome显示文摘 | Udai S. Kammula Eleanor J. Kuntz Todd D. Francone Zhaoshi Zeng Jinru Shia Ron G. Landmann Philip B. Paty Martin R. Weiser | 2006 | Cancer Letters2006，，2： | 2 |
| 8 | XANES analysis of tribo-chemical and thermal films generating from some organic polysulfides显示文摘X 光检查吸收近的边结构(XANES ) 光谱学第一被用来描绘从烷基,本甲基和包含酰的器官的 polysulfides 产生的 triboehemical 和热电影的化学性质。从这些 polysulfides 产生的热电影主要由 FeSO4l 和烷基化二硫组成,这被发现了也存在在表面下并且从包含酰的 polysulfides 产生的热电影的体积。Undertriboehemical 条件,电影的作文依赖于添加剂的分子结构。也就是,从烷基 polysulfide 产生的 triboehemical 电影由烷基化二硫组成在外面表面, FeSO_4 的混合物, FeS_2 和亚在表面下,并且 FeSO_4in 体积;为本甲基 polysulfide 的 triboehemical 电影的作文由 FeSO4 组成在外面,出现作文在表面下并且体积与烷基 polysulfide.For 一样是包含酰的 polysulfides, triboehemical 电影由烷基化二硫组成在外面表面,和 FeS_2 在表面下并且体积。 | YI Hongling ZENG Xiangqiong CAO Yan RENTianhui M. Kasrai G. M. Bancroft | 2006 | Chinese Science Bulletin2006，51，22： | 2 |
| 9 | Source apportionment of PM2.5 in Beijing by positive matrix factorization显示文摘 | Yu Song Yuanhang Zhang Shaodong Xie Limin Zeng Mei Zheng Lynn G. Salmon Min Shao Sjaak Slanina | 2005 | Atmospheric Environment2005，，8： | 1 |
| 10 | Metastatic and non-metastatic colorectal cancer (CRC) cells induce host metalloproteinase production in vivo显示文摘 | Susan Mc Donnell Vivek Chaudhry Jorge Mansilla-Soto Zhao-Shi Zeng Wei-ping Shu Jose G. Guillem | 1999 | Clinical and Experimental Metastasis1999，，4： | 1 |
| 11 | Systematic review and meta‐analysis of use of serum C‐reactive protein levels to predict anastomotic leak after colorectal surgery显示文摘 | P. P. Singh I. S. L. Zeng S. Srinivasa D. P. Lemanu A. B. Connolly A. G. Hill | 2014 | Br J Surg2014，，4： | 1 |
| 12 | Photoinitiating behavior of macrophotoinitiator containing aminoalkylphenone group显示文摘 | G. D. Ye H. Zhou J. W. Yang Z. H. Zeng Y. L. Chen | 2006 | Journal of Thermal Analysis and Calorimetry2006，，3： | 1 |
| 13 | Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch显示文摘 | Paul Cohen Julia D. Levy Yingying Zhang Andrea Frontini Dmitriy P. Kolodin Katrin J. Svensson James C. Lo Xing Zeng Li Ye Melin J. Khandekar Jun Wu Subhadra C. Gunawardana Alexander S. Banks Jo?o Paulo G. Camporez Michael J. Jurczak Shingo Kajimura David | 2013 | Cell2013，，： | 1 |
| 14 | Allelic differentiations and effects of the Rf3 and Rf4 genes on fertility restoration in rice with wild abortive cytoplasmic male sterility显示文摘 | J. Cai Q. P. Liao Z. J. Dai H. T. Zhu R. Z. Zeng Z. M. Zhang G. -Q. Zhang | 2013 | Biologia Plantarum2013，，2： | 1 |
| 15 | Targeted metabolic profiling of hepatocellular carcinoma and hepatitis C using LC ‐ MS / MS显示文摘 | Hamid Baniasadi G. A. Nagana Gowda Haiwei Gu Ao Zeng Shui Zhuang Nicholas Skill Mary Maluccio Daniel Raftery | 2013 | ELECTROPHORESIS2013，，19： | 1 |
| 16 | Skeletonized Internal Thoracic Artery Harvest Reduces Pain and Dysesthesia and Improves Sternal Perfusion After Coronary Artery Bypass Surgery: A Randomized, Double-Blind, Within-Patient Comparison显示文摘 | Munir Boodhwani B Khanh Lam Howard J. Nathan Thierry G. Mesana Marc Ruel Wanzhen Zeng Frank W. Sellke Fraser D. Rubens | 2006 | Circulation2006，，8： | 1 |
| 17 | Leaf nitrogen and phosphorus stoichiometry of Quercus species across China显示文摘 | Tonggui Wu Yi Dong Mukui Yu G. Geoff Wang De-Hui Zeng | 2012 | Forest Ecology and Management2012，，： | 1 |
| 18 | Investigation of thermal formability of aluminum alloy 4032显示文摘 | G. Fang P. Zeng | 2006 | Journal of Materials Engineering and Performance2006，，5： | 1 |
| 19 | Tension and Stress Calculations in a 3-D Fourier Model of Gall Bladder Geometry Obtained from MR Images显示文摘 | D. Liao B. U. Duch H. St?dkilde-J?rgensen Y. J. Zeng H. Gregersen G. S. Kassab | 2004 | Annals of Biomedical Engineering2004，，5： | 1 |
| 20 | Image-based plant modeling显示文摘 | L.Quan P.Tan G. Zeng L.Yuan J.Wang S.B.Kang | | 0，，03： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员