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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Development and evaluation of a rapid assay for the diagnosis of immunoglobulin E-mediated type I allergies显示文摘 | Lucassen R Fooke M Kleine-Tebbe | 2008 | Investig Allergol Clin lnmmnol2008，18，： | 1 |
| 3 | Mechanisms of thermal alteration of shale oils显示文摘 | FOOKES C J R DUFFY G J UDAJA P CHENSEE M D | 1990 | Fuel1990，69，9： | 1 |
| 4 | Clinical scale expansion of cy- tokine induced killer cells is feasible from healthy donors and patients with acute and chronic myeloid leukemia at various stages of therapy 显示文摘 | Niam M Linn YC Fook chong S | 2011 | Exp Hematol2011，39，9： | 1 |
| 5 | A comparative study of wavelet families for classification of wrist motions显示文摘 | Hariharan M Fook C Y Sindhu R | 2012 | Computers and Electrical Engineering2012，38，6： | 1 |
| 6 | Molecular epidemiology of rabies in Botswana: a comparison between antibody typing and nucleotide sequence phylogeny显示文摘 | N Johnson M Letshwenyo E.K Baipoledi G Thobokwe A.R Fooks | 2004 | Veterinary Microbiology2004，，1： | 1 |
| 7 | Residual thermal stresses in injection molding of thermoplastics : A theoretical and experimental study显示文摘 | Kamal M R Lai Fook R A Hernandez Aguilar J R | 2002 | Polymer Engineering and Science2002，42，5： | 1 |
| 8 | Interface characterization of an SiC particulate/ 6061 aluminum alloycomposite显示文摘 | FooKS Banks W M | 1994 | Composites1994，25，： | 1 |
| 9 | Development and evaluation of a rapid assay for the diagnosis of immunoglobulin E- mediated type I allergies 显示文摘 | Lucassen R Fooke M Kleine-Tebbe J | 2008 | J Investig Allergol Clin Immunol2008，18，3： | 1 |
| 10 | Pivotal role of dogs inrabies transmission,China显示文摘 | Tang X Luo M Zhang S Fooks A R Hu R Tu C | 2005 | Emerg Infect Dis2005，11，： | 1 |
| 11 | Clinical scale expansion of cytokine-induced killer cells is feasible from healthy donors and patients with acute and chronic myeloid leukemia at various stages of therapy显示文摘 | Niam M Linn YC Fook Chong S | | 0，，： | 1 |
| 12 | European bat lyssaviruses:an emerging zoonosis显示文摘 | FOOKS A R BROOKES S M JOHNSON N | 2003 | Epidemiol Infect2003，131，3： | 1 |
| 13 | Clinical scale expan- sion of cytokine- induced killer cells is feasible from healthy donors and patients with acute and chronic myeloid leukemia at various stages of therapy 显示文摘 | Niam M Linn YC Fook Chong S | 2011 | Exp Hematol2011，39，9： | 1 |
| 14 | Breast ultrasound in women with familial risk of breast cancer显示文摘 | Sim L S Hendriks J H Fook Chong S M | 2004 | Ann Acad Med Singapore2004，33，： | 1 |
| 15 | Drilling in mudrocks:rock behavior issues显示文摘 | Moheb A F Dusseault M B Fooks J C | 2003 | Journal of Petroleum Science and Engineering2003，38，2003： | 1 |
| 16 | CvL, a lectin from the marine sponge Cliona varians: isolation, characterization and its effects on pathogenic bacteria and Leishmania promastigotes 显示文摘 | Moura R M Queiruz A F Fook J M | 2006 | Comparative Biochemistry and Physiology A:Molecular & Integra- tive Physiology2006，145，4： | 1 |
| 17 | Clinical scale expansion of cytokine- induced killer cells is feasible from healthy donors and patients with acute and chronic myeloid leukemia at various stages of therapy显示文摘 | Niam M Linn YC Fook Chong S | 2011 | Exp Hematol2011，39，9： | 1 |
| 18 | Pat- terns of genome evolution that have accompanied host adaptation in Salmonella 显示文摘 | Langridge G C Fookes A M Connor T R | 2015 | Proc Natl Acad Sci USA2015，112，3： | 1 |
| 19 | Smart Wireless Continence Management system for persons with dementia 显示文摘 | Wai AA Fook VF Jayaehandran M | 2008 | Telemed J E Health2008，14，8： | 1 |
| 20 | Salmo- nella bongori provides insights into the evolution of the Salmonella显示文摘 | Fookes M Schroeder G N Langridge G C | 2011 | PLoS Pathog2011，7，10： | 1 |
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