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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Results,experience and technical points learnt with use of the SKy Bone Expander kyphoplasty system for osteoperotie vertebral compression fractures:a prospectire study of 40 patients with a minimum of 12 months of followup显示文摘 | YeoW Fook S | 2007 | Eur Spine J2007，16，11： | 1 |
| 3 | The effect of acupuncture on motor cortex excitability and plasticity显示文摘 | Yew Long Lo Cui S L Chong S Fook | 2005 | Neuroscience Letters2005，384，： | 1 |
| 4 | Results,experience and technical points learnt with use of the SKy Bone Expander kyphoplasty system for osteoporotic vertebral compression fractures:a prospective study of 40 patients with a minimum of 12 months of follow-up显示文摘 | Foo LS YeoW Fook S | 2007 | EurSpine J2007，16，11： | 1 |
| 5 | Peritoneal from colorectal cancer显示文摘 | Jayne DG Fook S Loi C | 2002 | BrJ Surg2002，89，12： | 1 |
| 6 | Clinical scale expansion of cy- tokine induced killer cells is feasible from healthy donors and patients with acute and chronic myeloid leukemia at various stages of therapy 显示文摘 | Niam M Linn YC Fook chong S | 2011 | Exp Hematol2011，39，9： | 1 |
| 7 | Prevention of rabies virus in-fection in dogs by a recombinant canine adenovirus type-2 encod-ing the rabies virus glycoprotein显示文摘 | Hu R Zhang S Fooks AR | 2006 | Microbes Infect2006，8，4： | 1 |
| 8 | Results,experience and technical points learnt with use of the SKy bone expander kyphoplasty system for osteoporotic vertebral compression fractures:A prospective study of 40 patients with a minimum of 12 months of follow-up显示文摘 | Foo LS Yeo W Fook S | 2007 | Eur Spine J2007，16，11： | 1 |
| 9 | Peritoneal carcinomatosis from eolo- rectal cancer显示文摘 | Jayne DG Fook S Loi C | 2002 | Br J Surg2002，89，12： | 1 |
| 10 | Oral vaccination of dogs(Ca-nis familiaris)with baits containing the recombinant rabies-ca-nine adenovirus type-2 vaccine confers long-lasting immunity a-gainst rabies显示文摘 | Zhang S Liu Y Fooks AR | 2008 | Vaccine2008，26，3： | 1 |
| 11 | Peritoneal carcinomatosis from colorectal cancer显示文摘 | Jayne D G Fook S Loi C | 2002 | Br J Surg2002，89，6： | 1 |
| 12 | Botulinum toxin improves quality of life in hemifacial spasm: validation of a questionnaire (HFS-30)显示文摘 | Tan E K Fook Chong S Lum S Y | 2004 | J Neurol Sci2004，219，12： | 1 |
| 13 | Measles Virus - induced Immune Suppression in the Cotton Rat (Sigmodon hispidus) Model Depends on Viral Glycoproteins显示文摘 | Niewiesk S Eisenhuth I Fooks A | 1997 | Virol1997，71，： | 1 |
| 14 | Design and development of automatic visual inspection system for PCB manufacturing 显示文摘 | MAR N S S YARLAGADDA P K D V FOOKES C | 2011 | Robotics and Com- puter Integrated Manufacturing2011，27，5： | 1 |
| 15 | Rock weathering in engineering time显示文摘 | FOOKES P G GOURLEY C S OHIKERE C | 1988 | Quarterly Journal of Engineering Geology1988，21，： | 1 |
| 16 | Prevention of rabies virus infection in dogs by a recombinant canine adenovirus type-2 encoding the rabies virus glycoprotein显示文摘 | Hu R Zhang S Fooks A R | 2006 | Microbes Infect2006，8，4： | 1 |
| 17 | Design of auto- matic vision-based inspection system for solder joint segmen- tation显示文摘 | Mar N S S Fookes C Yarlagadda P K D V | 2009 | Journal of Achievements in Materials and Manu- facturing Engineering2009，34，2： | 1 |
| 18 | Pivotal role of dogs inrabies transmission,China显示文摘 | Tang X Luo M Zhang S Fooks A R Hu R Tu C | 2005 | Emerg Infect Dis2005，11，： | 1 |
| 19 | Clinical scale expansion of cytokine-induced killer cells is feasible from healthy donors and patients with acute and chronic myeloid leukemia at various stages of therapy显示文摘 | Niam M Linn YC Fook Chong S | | 0，，： | 1 |
| 20 | European bat lyssaviruses:an emerging zoonosis显示文摘 | FOOKS A R BROOKES S M JOHNSON N | 2003 | Epidemiol Infect2003，131，3： | 1 |
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