|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The material and biological characteristics of osteoinductive calcium phosphate ceramics显示文摘The discovery of osteoinductivity of calcium phosphate(Ca-P)ceramics has set an enduring paradigm of conferring biological regenerative activity to materials with carefully designed structural characteristics.The unique phase composition and porous structural features of osteoinductive Ca-P ceramics allow it to interact with signaling molecules and extracellular matrices in the host system,creating a local environment conducive to new bone formation.Mounting evidence now indicate that the osteoinductive activity of Ca-P ceramics is linked to their physicochemical and three-dimensional structural properties.Inspired by this conceptual breakthrough,many laboratories have shown that other materials can be also enticed to join the rank of tissue-inducing biomaterials,and besides the bones,other tissues such as cartilage,nerves and blood vessels were also regenerated with the assistance of biomaterials.Here,we give a brief historical recount about the discovery of the osteoinductivity of Ca-P ceramics,summarize the underlying material factors and biological characteristics,and discuss the mechanism of osteoinduction concerning protein adsorption,and the interaction with different types of cells,and the involvement of the vascular and immune systems. | Zhurong Tang Xiangfeng Li Yanfei Tan Hongsong Fan Xingdong Zhang | 2018 | Regenerative Biomaterials2018，5，1： | 20 |
| 2 | A cellular automata evacuation model considering friction and repulsion显示文摘There exist interactions among pedestrians and between pedestrian and environment in evacuation. These interactions include attraction, repulsion and friction that play key roles in human evacuation behaviors, speed and efficiency. Most former evacuation models focus on the attraction force, while repulsion and friction are not well modeled. As a kind of multi-particle self-driven model, the social force model introduced in recent years can represent those three forces but with low simulation efficiency because it is a continuous model with complex rules. Discrete models such as the cellular automata model and the lattice gas model have simple rules and high simulation efficiency, but are not quite suitable for interactions’ simulation. In this paper, a new cellular automata model based on traditional models is introduced in which repulsion and friction are modeled quantitatively. It is indicated that the model can simulate some basic behaviors, e.g. arching and the “faster-is-slower” phenomenon, in evacuation as multi-particle self-driven models, but with high efficiency as the normal cellular automata model and the lattice gas model. | SONG Weiguo YU Yanfei FAN Weicheng Zhang Heping | 2005 | Science China(Technological Sciences)2005，48，4： | 19 |
| 3 | Optimizing the CRISPR/Cas9 system for genome editing in grape by using grape promoters显示文摘The efficacy of the CRISPR/Cas9 system in grapevine(Vitis vinifera L.)has been documented,but the optimization of this system,as well as CRISPR/Cas9-mediated multiplex genome editing,has not been explored in this species.Herein,we identified four VvU3 and VvU6 promoters and two ubiquitin(UBQ)promoters in grapevine and demonstrated that the use of the identified VvU3/U6 and UBQ2 promoters could significantly increase the editing efficiency in grape by improving the expression of sgRNA and Cas9,respectively.Furthermore,we conducted multiplex genome editing using the optimized CRISPR/Cas9 vector that contained the conventional multiple sgRNA expression cassettes or the polycistronic tRNA-sgRNA cassette(PTG)by targeting the sugar-related tonoplastic monosaccharide transporter(TMT)family members TMT1 and TMT2,and the overall editing efficiencies were higher than 10%.The simultaneous editing of TMT1 and TMT2 resulted in reduced sugar levels,which indicated the role of these two genes in sugar accumulation in grapes.Moreover,the activities of the VvU3,VvU6,and UBQ2 promoters in tobacco genome editing were demonstrated by editing the phytoene desaturase(PDS)gene in Nicotiana benthamiana leaves.Our study provides materials for the optimization of the CRISPR/Cas9 system.To our knowledge,our simultaneous editing of the grape TMT family genes TMT1 and TMT2 constitutes the first example of multiplex genome editing in grape.The multiplex editing systems described in this manuscript expand the toolbox of grape genome editing,which would facilitate basic research and molecular breeding in grapevine. | Chong Ren Yanfei Liu Yuchen Guo Wei Duan Peige Fan Shaohua Li Zhenchang Liang | 2021 | Horticulture Research2021，8，1： | 6 |
| 4 | Zircon SHRIMP U-Pb Dating of the Tourmalinites from Boron-bearing Series of Borate Deposits in Eastern Liaoning and its Geological Implications显示文摘This paper focused on the zircon sensitive high resolution ion micro-probeU-Pb geochronology of the tourmalinites from boron-bearing series of borate deposits in Eastern Liaoning.The zircons commonly have core-rim structures,most cores show oscillatory zoning in cathodoluminescence and plane polarized light images,suggesting a magmatic detrital origin.Ages of the magmatic detrital zircons from the hyalotourmalite samples(N13) and(N14) are 2175±5Ma and 2171±9Ma,respectively.Moreover,metamorphic zircon from the sample(N13) shows an age of 1906±4Ma.Zircon core and rim from the hyalotourmalite sample(N02) record ages of 2171±6Ma and 1889±62Ma,which are explained as indicating the formation and metamorphic ages.Combined with the geological and geochemical studies,it can be concluded that the tourmalinites are formed during sedimentary exhalative mineralizations in the mid-Paleoproterozoic(~2170Ma) and underwent the metamorphism in the late-Paleoproterozoic(~1900Ma).The tourmalinites are the products of submarine acid volcanism in the extension rifting phase of the Liaoji Paleoproterozoic Rift,the rock-forming materials of which are derived from the mantle sources with recycling crustal contamination.The emergence of tourmalinites not only indicates the mid-Paleoproterozoic tectonic-magmatic processes,but also provides impetus,heat and material sources for the mineralization of borate deposits in Eastern Liaoning. | LIU Jingdang XIAO Rongge ZHANG Yanfei FAN Minghui WANG Shengzhi JIA Yuguo WANG Gang LIU Zhixue | 2012 | Acta Geologica Sinica(English Edition)2012，86，1： | 5 |
| 5 | Network coding based privacy preservation against traffic analysis in multi-hop wireless networks显示文摘 | Fan Yanfei Jiang Yixin Zhu Haojin | 2011 | IEEE Transactions on Wireless Communications2011，10，3： | 1 |
| 6 | DSC Analysis of Isothermal Melt-crystallization, Glass Transition and Melting Behavior of Poly (1-lactide) with Different Molecular Weights显示文摘 | He Yong Fan Zhongyong Hu Yanfei | 2007 | European Polymer Journal2007，43，44： | 1 |
| 7 | Depressed transition temperature of WxV1–xO2 mechanistic insights from the X-ray absorption fine structure(XAFS) spectroscopy显示文摘 | WU Yanfei FAN Lele HUANG Weifeng | 2014 | Phys Chem C hem Phys2014，16，17： | 1 |
| 8 | Network coding based privacy preservation against traffic analysis in multi-hop wireless networks显示文摘 | FAN Yanfei JIANG Yixin ZHU Haojin | 2011 | IEEE Transactions on Wireless Communications2011，10，3： | 1 |
| 9 | Common risk factors for chronic non- communicable diseases among older adults in China 显示文摘 | Wu Fan Guo Yanfei Chatterji S | 2015 | BMC Public Health2015，15，1： | 1 |
| 10 | Retrieval of the aerosol particle size distribution function by incorporating a priori information显示文摘 | Yanfei Wang Shufang Fan Xue Feng | 2007 | Journal of Aerosol Science2007，，8： | 1 |
| 11 | Tobacco Rattle Virus-induced Phytoene Desaturase (PDS) Silencing in Centaurea cyanus显示文摘Virus-induced gene silencing(VIGS)is a genetic tool used to assess gene function.Tobacco rattle virus(TRV)is a VIGS vector commonly used to induce endogenous gene silencing in plants.However,there is no VIGS system established for Centaurea spp.We evaluated the effectiveness of a TRV-based VIGS system using phytoene desaturase(PDS)as a reporter gene in Centaurea cyanus.Three methods including pressure-,vacuum-and apical meristem-infiltrationwere tested to infect C.cyanus seedlings.Photobleached leaveswere only obtained using apicalmeristem-infiltration after a 14 d treatment.The CcPDS transcripts in photobleached leaves were significantly reduced compared with that in green leaves treated with empty TRV.Four C.cyanus cultivars were tested to detect their VIGS responses,and‘Dwarf Tom Pouce Blue’was the most sensitive.The agro-infiltration condition was optimized by screening for the optimal seedling stage as well as the optimum Agrobacterium density for efficient silencing.Seedlings with four true leaves and infiltration with an Agrobacterium density of OD_(600)0.5 were optimal conditions to obtain more photobleached leaves and more intense photobleached phenotype.The results demonstrated the feasibility of TRV-based VIGS for functional analysis of genes in C.cyanus. | Chengyan Deng Fan Zhang Jiaying Wang Yanfei Li He Huang Silan Dai | 2021 | Horticultural Plant Journal2021，7，2： | 1 |
| 12 | Functional characterization of a special thermophilic multifunctional amylase OPMA-N and its N-terminal domain显示文摘编码特殊 thermophilic 的基因多功能的淀粉酶 OPMA-N 从杆菌 sp 被克隆。ZW2531-1。OPMA-N 与典型淀粉酶相比有一个另外的 124 残余 N 终端领域并且与一张 -pleated 表和随机的卷结构形成一个相对独立的领域。这里,我们在 OPMA-N 的功能和性质上报导了不平常的底层和 OPMA-N 的产品特性和另外的 N 终端领域(1124 aa ) 的影响。OPMA-N (12.82 U/mg ) 和它的 N 终端截断域的 OPMA-N (12.55 U/mg ) 仅仅降级了包括麦芽糖, maltotriose, isomaltotriose,和 isomaltotetraose 生产 oligosaccharides,然而并非生产葡萄糖的淀粉。因此, N 终端领域没决定它被它的 C 终端 -pleated 表结构可能调整的底层和产品特性。然而, OPMA-N 的 N 终端领域似乎调制它的催化特征,导致更多的 isomaltotriose 和更少的麦芽糖的生产,并且自从 OPMA-N 从 40 ~ 80 在一个温度范围比 OPMA-N 显示出更高的活动,它似乎贡献 OPMA-N 的 | Fan Li Xuejun Zhu Yanfei Li Hao Cao Yingjiu Zhang | 2011 | Acta Biochimica et Biophysica Sinica2011，43，4： | 1 |
| 13 | Applications and recent advances of rare earth in solid oxide fuel cells显示文摘Solid oxide fuel cells(SOFCs)are an all-solid energy conversion device from the chemical energy of fuels to electric energy at intermediate and high temperatures.Up to now,massive efforts have been made in developing different components of solid oxide fuel cells,including electrolyte,anode,cathode and interconnect materials.Rare earth elements play an indispensable role in different components of SOFCs which have been extensively studied in the recent decades.In this review,we concentrate upon the rare earth application and recent advances in SOFCs and related materials.Materials structure involves perovskites,Ruddlesden-Popper,fluorite,spinel,pyrochlore,apatite and so on.Moreover,the effects of rare earth based oxides as matrix or dopants in different components are also discussed.Structures and properties of the materials are related to the element type,valence,coordination and ion radius.This article will provide a comprehensive research direction towards SOFCs components for their composition,structural design and mechanisms research. | Qi Wang Hui Fan Yanfei Xiao Yihe Zhang | 2022 | Journal of Rare Earths2022，40，11： | 1 |
| 14 | Strong phonon-magnon coupling of an O/Fe(001) surface显示文摘Using density functional calculations,we elucidate the interaction between magnons and phonons on Fe(001)and O/Fe(001)surfaces.The effective Heisenberg exchange parameters between neighbor sites(Ji)were derived by fitting the ab initio spin spiral dispersion relation to a classical Heisenberg model.In bulk Fe,J5bhas a larger amplitude than J2b-J4b.Surface magnons were softer on the Fe(001)surface than in bulk,but were strengthened on the O/Fe(001)surface through strong interactions between the O and Fe atoms.The four calculated high-energy phonon modes of O/Fe(001)excellently agreed with the experimental measurements.The J1in O/Fe(001)decreased significantly with increasing phonon amplitude.Phonon-magnon coupling occurred more easily on O/Fe(001)than on Fe(001).The softening of the magnon on the O/Fe(001)with phonon amplitude was attributed to the reduced amplitude of longitudinal excitations.Magnetic moment of the Fe atom of the second layer(Fe2)was especially sensitive to phonon amplitude,regardless of the motion direction of the Fe2 atoms. | Yan Zhu YanFei Pan JiYu Fan ChunLan Ma Jun Hu XinYuan Wei KaiCheng Zhang HongBin Zhang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，11： | 0 |
| 15 | Effects of Several Passivating Agents on Improvement of Cd Polluted Soil显示文摘Clay minerals,phosphates,alkaline materials,organic materials are common improvers in the management of Cd polluted soil. This paper systematically summarized types of common soil improvers and their passivation mechanism of Cd in soil. It reviewed advances in researches of soil improvers. Besides,it introduced major problems in four common passivating agents for management of Cd polluted soil. Finally,according to different mechanism characteristics of passivating agents,it came up with some recommendations. | Yuying ZHAO Yongxian LIU Zhilian FAN Yanfei HUANG Liping PAN Mengling NONG Shiyang LU Jinping CHEN Xiu LAN | 2017 | Asian Agricultural Research2017，9，10： | 0 |
| 16 | Flexible mille-feuille structure electromagnetic interference shielding film with excellent thermal conductivity and Joule heating显示文摘The intelligent electronic devices have urgent demands for electromagnetic interference(EMI)shielding films with excellent heat dissipation capability.However,it is challenging to obtain excellent EMI shielding and thermal conductivity performances simultaneously.Herein,inspired by mille-feuille structure,the multifunctional EMI shielding films developed by a layer-by-layer self-assembly and hot-pressing strategy.The ingenious introduction of silver nanoparticles(AgNPs)with large specific surface area and highly conductive into the network formed by TEMPO-oxidized cellulose nanofibrils(TOCNFs)with large aspect ratio to form the TOCNFs/AgNPs.And the graphene nanoplates(GNPs)with high conductivity loss distributed alternately with TOCNFs/AgNPs to construct mille-feuille structure,which had highly efficient conductive network,complete thermally conduction pathway and rich heterogeneous interfaces.Consequently,the designed films presented high electrical conductivity of 8520 S/cm,superb EMI effectiveness(SE)of 98.05 dB,and excellent thermal conductivity of 18.82 W/(m·K).Furthermore,the films possessed outstanding Joule heating performances with low voltages,including high heating temperature(100℃),fast response time(<20 s),and impressive heating stability and reliability.Thus,such high-performance EMI shielding films with fascinating thermal conductivity and Joule heating performances have substantial application in flexible electronics,electromagnetic waves shielding and thermal management. | Dingwen Yin Huijuan Xiu Simin Wang Yanfei Pan Na Li Rui Cheng Shaoyan Huang Sha Fan Jinbao Li | 2024 | Nano Research2024，17，5： | 0 |
| 17 | Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma显示文摘Detailed characterizations of genomic alterations have not identified subtype-specific vulnerabilities in adult gliomas. Mapping gliomas into developmental programs may uncover new vulnerabilities that are not strictly related to genomic alterations. After identifying conserved gene modules co-expressed with EGFR or PDGFRA (EM or PM), we recently proposed an EM/PM classification scheme for adult gliomas in a histological subtype- and grade-independent manner. By using cohorts of bulk samples, paired primary and recurrent samples, multi-region samples from the same glioma, single-cell RNA-seq samples, and clinical samples, we here demonstrate the temporal and spatial stability of the EM and PM subtypes. The EM and PM subtypes, which progress in a subtype-specific mode, are robustly maintained in paired longitudinal samples. Elevated activities of cell proliferation, genomic instability and microenvironment, rather than subtype switching, mark recurrent gliomas. Within individual gliomas, the EM/PM subtype was preserved across regions and single cells. Malignant cells in the EM and PM gliomas were correlated to neural stem cell and oligodendrocyte progenitor cell compartment, respectively. Thus, while genetic makeup may change during progression and/or within different tumor areas, adult gliomas evolve within a neurodevelopmental framework of the EM and PM molecular subtypes. The dysregulated developmental pathways embedded in these molecular subtypes may contain subtype-specific vulnerabilities. | Jing Feng Zheng Zhao Yanfei Wei Zhaoshi Bao Wei Zhang Fan Wu Guanzhang Li Zhiyan Sun Yanli Tan Jiuyi Li Yunqiu Zhang Zejun Duan Xueling Qi Kai Yu Zhengmin Cong Junjie Yang Yaxin Wang Yingyu Sun Fuchou Tang Xiaodong Su Chuan Fang Tao Jiang Xiaolong Fan | 2023 | Frontiers of Medicine2023，17，2： | 0 |
| 18 | Molecular Cloning and Bioinformatics Analysis of kdpE Gene from Vibrio alginolyticus显示文摘The two-component regulatory system plays an important role in the growth and virulence of bacteria.In this study,the phosphate transcriptional regulatory protein (KdpE) gene of Vibrio alginolyticus strain HY9901 was cloned.Sequence analysis revealed that the length of kdp E gene is 732 bp and encodes a putative protein of 243 amino acids.The predicted molecular weight (MW) of Kdp E was 27.66 k D with an estimated p I of 5.01.Using SignalP 4.0 and TMHMM Server 2.0 software,it was predicted that the Kdp E protein was located in cytoplasm.It did not contain a signal peptide or a transmembranous region.A phylogenetic tree was constructed by MEGA 5.0 software,indicating that the Kdp E of V.alginolyticus had high genetic relationship with Vibrio campbellii and Vibrio parahaemolyticus.Using SWISS-MODEL work-space,the three-dimensional structures of conserved domain REC in the Kdp E was determined.These results can provide a basis for further studies on the two-component regulatory systems of V.alginolyticus. | Hong Shunhua Yang Fan Pang Huanying Zhang Yanfei Song Dawei Wang Zhiwen Lu Yishan Jian Jichang | 2016 | Animal Husbandry and Feed Science2016，8，5： | 0 |
| 19 | Visualization Analysis for Business Performance of Chinese Listed Companies Based on Gephi显示文摘When conducting company performance evaluations,the traditional method cannot reflect the distribution characteristics of the company’s operating conditions in the entire securities market.Gephi is an efficient tool for data analysis and visualization in the era of big data.It can convert the evaluation results of all listed companies into nodes and edges,and directly display them in the form of graphs,thus making up for the defects of traditional methods.This paper will take all the listed companies in the Shanghai and Shenzhen Stock Exchange as the analysis object.First uses tushare and web crawlers to collect the financial statement data of these companies.And then,uses the Economic Value Added model to calculate the EVA of each listed company and build graph data.Next,import the graph data into gephi to generate the distribution graph of all listed companies’performance,and summarize the distribution characteristics of business performance.Finally,select a listed company that you want to analyze in detail,using the traditional DuPont analysis method to conduct micro level visualization analysis of the business performance to find the main factors affecting the company’s operating performance.Incorporating gephi into traditional performance analysis methods will make the results of traditional analytical methods more effective and complete. | Guang Sun Hongzhang Lv Dianyu Wang Xiaoping Fan Yi Zuo Yanfei Xiao Xu Liu Wenqian Xiang Ziyi Guo | 2020 | Computers, Materials & Continua2020，，5： | 0 |
| 20 | Molecular Cloning and Bioinformatics Analysis of kdpD Gene from Vibrio alginolyticus显示文摘In this study,histidine kinase gene kdpD in the two-component regulatory system of Vibrio alginolyticus strain HY9901 was cloned for bioinformatics analysis. Sequence analysis revealed that kdpD gene( GenB ank accession number: KJ544668) was 1 374 bp in length,encoding a putative protein of 457 amino acids. The predicted molecular weight( MW) of KdpE was 51. 60 kD with a theoretical isoelectric point( pI) of 6. 02. Using SignalP 4. 0,TMHMM Server 2. 0 and SoftB erry-Psite software,it was predicted that KdpE protein was equally located in Golgi apparatus,plasma membrane and endoplasmic reticulum( 33. 3%),which did not contain a signal peptide but contained three transmembrane domains. KdpE protein had five casein kinase II phosphorylation sites,five protein kinase C phosphorylation sites and one cA MP- and cG MP-dependent protein kinase phosphorylation site. A phylogenetic tree was constructed by MEGA 5. 0 software,which revealed that KdpD from V. alginolyticus had close genetic relationship with corresponding proteins from V. campbellii and V. parahaemolyticus. Using SWISSMODEL Workspace,the three-dimensional structure of HATPase_c conserved domain in KdpD protein was constructed. These results may provide the basis for further studies on two-component regulatory system KdpD/KdpE of V. alginolyticus. | Haitao LIU Fan YANG Huanying PANG Yanfei ZHANG Dawei SONG Shuhe CHEN Ganlin WU Jichang JIAN | 2016 | Agricultural Biotechnology2016，5，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员