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| 1 | Histopathological changes in gills of the estuarine crab Chasmagnathus granulata (Crustacea-Decapoda) following acute exposure to ammonia显示文摘 | Mauro de Freitas Rebelo Enrique M. Rodriguez Euclydes A. Santos Mart??n Ansaldo | 2000 | Comparative Biochemistry and Physiology Part C: Comparative Pharmacology and Toxicology2000，，2： | 1 |
| 2 | Immune response modulation in inflammatory bowel diseases by Helicobacter pylori infection显示文摘Many studies point to an association between Helicobacter pylori(H.pylori)infection and inflammatory bowel diseases(IBD).Although controversial,this association indicates that the presence of the bacterium somehow affects the course of IBD.It appears that H.pylori infection influences IBD through changes in the diversity of the gut microbiota,and hence in local chemical characteristics,and alteration in the pattern of gut immune response.The gut immune response appears to be modulated by H.pylori infection towards a less aggressive inflammatory response and the establishment of a targeted response to tissue repair.Therefore,a T helper 2(Th2)/macrophage M2 response is stimulated,while the Th1/macrophage M1 response is suppressed.The immunomodulation appears to be associated with intrinsic factors of the bacteria,such as virulence factors-such oncogenic protein cytotoxin-associated antigen A,proteins such H.pylori neutrophil-activating protein,but also with microenvironmental changes that favor permanence of H.pylori in the stomach.These changes include the increase of gastric mucosal pH by urease activity,and suppression of the stomach immune response promoted by evasion mechanisms of the bacterium.Furthermore,there is a causal relationship between H.pylori infection and components of the innate immunity such as the NLR family pyrin domain containing 3 inflammasome that directs IBD toward a better prognosis. | Gabriella Feilstrecker Balani Mariana dos Santos Cortez Jayme Euclydes Picasky da Silveira Freitas Fabrício Freire de Melo Ana Carla Zarpelon-Schutz Kádima Nayara Teixeira | 2023 | World Journal of Gastroenterology2023，29，30： | 0 |
| 3 | The roles of anurans in antagonistic networks are explained by life-habit and body-size显示文摘Interactions among living beings are the structuring basis of ecosystems,and studies of networks allow us to identify the patterns and consistency of such interactions.Antagonistic networks reflect the energy flow of communities,and identifying network structure and the biological aspects that influence its stability is crucial to understanding ecosystem functioning.We used antagonistic anuran interactions-predator-prey and host-parasite-to assess structural patterns and to identify the key anuran species structuring these networks.We tested whether anuran body-size and life-habit are related to their roles in these networks.We collected individuals of 9 species of anurans from an area of the Atlantic Forest in Brazil and identified their prey and helminth parasites.We used network(modularity,specialization,and nestedness)and centrality metrics(degree,closeness,and betweenness)to identify the role of anuran species in both networks.We then evaluated whether anuran body-size or life-habit were related to anuran centrality using generalized linear mixed models.The networks formed specialized interactions in compartments composed by key species from different habits.In our networks,anurans with rheophilic and cryptozoic habit are central in predator-prey networks,and those with larger body size and arboreal and cryptozoic habit in the host-parasite network.This study represents a step towards a better understanding of the influential factors that affect the structure of anuran antagonist networks,as well as to recognize the functioning roles of anuran species. | Amanda Caroline DUDCZAK Gabriel Massaccesi DE LA TORRE Lorena EUCLYDES Karla Magalhães CAMPIÃO | 2022 | Integrative Zoology2022，17，4： | 0 |
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