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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 3 | CMOS Image sensor :electronic camera-on-a-chip显示文摘 | Eric R F | 1997 | IEEE Transactions on Electron Devices1997，44，16： | 1 |
| 4 | Rumor and Gossip Research 显示文摘 | Rosnow R L Eric K F | 2005 | Psy- chological Science Agenda2005，，： | 1 |
| 5 | Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial显示文摘 | George L Bakris Pantelis A Sarafidis Matthew R Weir Bj?rn Dahl?f Bertram Pitt Kenneth Jamerson Eric J Velazquez Linda Staikos-Byrne Roxzana Y Kelly Victor Shi Yann-Tong Chiang Michael A Weber | 2010 | The Lancet2010，，9721： | 1 |
| 6 | Association between dietary patterns and plasma biomarkers of obesity and cardiovascular disease risk 显示文摘 | TERESA T F ERIC B R DONNA S | 2001 | Am J Clin Nutr2001，73，： | 1 |
| 7 | BAI 3, CDX 2 and VIL 1: a panel of three antibodies to distinguish small cell from large cell neuroendocrine lung carcinomas显示文摘 | Muhammad F Bari Helen Brown Andrew G Nicholson Keith M Kerr John R Gosney William A Wallace Irshad Soomro Salli Muller Danielle Peat Jonathan D Moore Lesley A Ward Maxim B Freidin Eric Lim Manu Vatish David R J Snead | 2014 | Histopathology2014，，： | 1 |
| 8 | A room-temperature molten salt prepared from AuCl3 and 1-ethyl-3-methylimidazolium chloride显示文摘 | Eric R S Jonathan E S Michael F O | 1999 | Inorg Chem1999，38，17： | 1 |
| 9 | 1,3-Dithietane显示文摘 | Eric B Eugene R C Paul F S | 1976 | J Am Chem Soc1976，98，： | 1 |
| 10 | The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens显示文摘 | Eric D Christophe R Lionel F | 2003 | Nature Biotechnology2003，21，11： | 1 |
| 11 | Numerical simulation of oblique impact on orbital debris shielding显示文摘 | Robert J R Eric P F | 1999 | Int J Impact Engineering1999，23，： | 1 |
| 12 | Global estimates of evapotranspiration for climate studies using multi-sensor remote sensing data:Evaluation of three process-based approaches显示文摘 | Raghuveer K V Eric F W Craig R F | 2011 | Remote Sensing of Environment2011，115，3： | 1 |
| 13 | A Randomized Study of Financial Incentives to Increase Physical Activity among Sedentary Older Adults显示文摘 | Eric A F Derek S B David R B | 2008 | Prevention M edicine2008，，11： | 1 |
| 14 | Global desertification: building a science for dry land development显示文摘 | JAMES F R MARK S S ERIC F L | 2007 | Science2007，316，5826： | 1 |
| 15 | Interactions of bacteriophage and host macromolecules in the growth of bacteriophage X显示文摘 | DAVID I F ERIC R COSTA G KIT T IRA H FLORA B | 1984 | Microbiological Reviews1984，48，4： | 1 |
| 16 | Genome-wide analysis of mutations in mutant lineages selected following fast-neutron irradiation mutagenesis of Arabidopsis thaliana显示文摘 | Eric J B Xiangchao G Aziz M Carly B Caifu J Keara F Elizabeth A Anjar W Marko J Kit B Sharan K Jiannis R Richard M Nicholas P H | 2012 | Genome Research2012，22，： | 1 |
| 17 | Tobacco irri- gation: Supplemental watering of a high value, drought tolerant crop in a humid region显示文摘 | Caldwell Eric F Leib Brian G Buchanan John R | 2010 | Applied Engineering in Agriculture2010，，26： | 1 |
| 18 | Gas diffusion-its impact on a horizontal HPHT well显示文摘 | NIGEL D B ERIC LOW AAS B ROMMETVEIT R LARSEN H F | 2002 | SPE2002，，： | 1 |
| 19 | Challenges in comparing risk-adjusted bypass surgery mortality results显示文摘 | Eric D Peterson Elizabeth R DeLong Lawrence H Muhlbaier Allison B Rosen Hope E Buell Catarina I Kiefe Timothy F Kresowik | 2000 | Journal of the American College of Cardiology2000，，： | 1 |
| 20 | Current development of mTOR inhibitors as anticancer agents 显示文摘 | Sandrine F Guido K Eric R | 2006 | Nature Reviews Drug Discovery2006，5，： | 1 |
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