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| 1 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 2 | Response to endoscopic therapy for biliary anastomotic strictures in deceased versus living donor liver transplantation显示文摘BACKGROUND:Endoscopic therapy has been successful in the management of biliary complications after both deceased donor liver transplantation(DDLT) and living donor liver transplantation(LDLT).LDLT is thought to be associated with higher rates of biliary complications,but there are few studies comparing the success of endoscopic management of anastomotic strictures between the two groups.This study aims to compare our experience in the endoscopic management of anastomotic strictures in DDLT versus LDLT.METHODS:This is a retrospective database review of all liver transplant patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) after liver transplantation.The frequency of anastomotic stricture and the time to develop and to resolve anastomotic stricture were compared between DDLT and LDLT.The response of anastomotic stricture to endoscopic therapy was also analyzed.RESULTS:A total of 362 patients underwent liver transplantation between 2003 and 2011,with 125 requiring ERCP to manage biliary complications.Thirty-three(9.9%) cases of DDLT and 8(27.6%) of LDLT(P=0.01) were found to have anastomotic stricture.When comparing DDLT and LDLT,there was no difference in the mean time to the development of anastomotic strictures(98±17 vs 172±65 days,P=0.11),likelihood of response to ERCP [22(66.7%) vs 6(75.0%),P=0.69],mean time to the resolution of anastomotic strictures(268±77 vs 125±37 days,P=0.34),and the number of ERCPs required to achieve resolution(3.9±0.4 vs 4.7±0.9,P=0.38).CONCLUSIONS:Endoscopic therapy is effective in the majority of biliary complications relating to liver transplantation.Anastomotic strictures occur more frequently in LDLT compared with DDLT,with equivalent endoscopic treatment response and outcomes for both groups. | Calvin HY Chan Fergal Donnellan Michael F Byrne Alan Coss Mazhar Haque Holly Wiesenger Charles H Scudamore Urs P Steinbrecher Alan A Weiss Eric M Yoshida | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，5： | 7 |
| 3 | High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6. | Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders | 2016 | Horticulture Research2016，3，1： | 6 |
| 4 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 5 | Zika virus in Gabon(Central Africa)-2007:a new threat from Aedes albopictus?显示文摘 | Grard G Mélanie C Illich Manfred M DieudonnéN Statiana MO Davy J Didier F Christophe P Eric Maurice L | 2014 | PLoS Negl Trop Dis2014，8，2： | 1 |
| 6 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 1 |
| 7 | Numerical simulation of oblique impact on orbital debris shielding显示文摘 | Robert J R Eric P F | 1999 | Int J Impact Engineering1999，23，： | 1 |
| 8 | Effect of maternal ethanol intake on fetal rabbit gastrointestinal development 显示文摘 | Guo W H Jeffrey P G Eric W F | 1994 | J Pediatr Surg1994，29，： | 1 |
| 9 | Conflict resolution problems for air traffic management system solved with mixed integer programming显示文摘 | Lucia P Eric M F Antonio B | 2002 | IEEE Transactions on Intelligent Transportation System2002，3，1： | 1 |
| 10 | Surface soil moisture parameterization of the VIC-2L model : Evaluation and modification 显示文摘 | Xu L Eric F W Dennis P L | 1996 | Global Planet Change1996，13，： | 1 |
| 11 | Water-mediated catalyst pre- activation :an efficient protocol for C-N cross-coupling re- actions显示文摘 | Brett P F Philipp K Eric S | 2008 | Org Lett2008，10，16： | 1 |
| 12 | Modeling convective drying of ventilatedwallchambers inbuilding enclosures显示文摘 | Davidovic Danko Srebric Jelena Burnett Eric F P | 2006 | Internatinoal Journal of Thermal Sciences2006，，45： | 1 |
| 13 | A simple hydrologically based model of land surface water and energy fluxes for general circulation models 显示文摘 | XU Liang DENNIS P ERIC F | 1994 | Journal of Geophysical Research1994，，14： | 1 |
| 14 | Genome-wide analysis of mutations in mutant lineages selected following fast-neutron irradiation mutagenesis of Arabidopsis thaliana显示文摘 | Eric J B Xiangchao G Aziz M Carly B Caifu J Keara F Elizabeth A Anjar W Marko J Kit B Sharan K Jiannis R Richard M Nicholas P H | 2012 | Genome Research2012，22，： | 1 |
| 15 | Effects of Digital Elevation Model Accuracy on Hydrologic Predictions显示文摘 | Tracey Kenward Dennis P Lettenmaier Eric F Wood Eric Fielding | 2000 | Remote Sensing of Environment2000，，3： | 1 |
| 16 | Time-use data analysis and modeling: toward the next generation of transportation planning methodologies显示文摘 | Ryuiehi K Satoshi F Eric I P | 1997 | Transport Policy1997，4，3： | 1 |
| 17 | Phenotypes of Th lineages generated by the commonly used activation with anti-CD3/CD28 antibodies differ from those generated by the physiological activation with the specific antigen显示文摘T 助手(Th ) 系被在极化期间与 anti-CD3/CD28 抗体激活 CD4 房间在 vitro 产生了。然而,生理地, Th 系的产生被介绍抗原的房间(APC ) 被有特定的抗原的激活介绍。这里,我们使用了 T 房间受体(TCR ) 当在二个激活模式中的任何一个一个产生了时,比较 Th1, Th9 和 Th17 系的显型的转基因的老鼠。对母鸡鸡蛋溶解酵素(司死亡及冥府的女神) 特定的系 Th 房间,采纳地被变成转基因地在他们的透镜表示司死亡及冥府的女神的接受者老鼠。显著差别在 Th1, Th9 或 Th17 的系之间被发现,在他们的能力在二个模式中的任何一个一个产生了移居到并且在接受者怒气并且,重要地增殖在接受者老鼠眼睛导致发炎。实质的差别也在他们某些 chemokines 和 chemokine 受体的抄本表示侧面在系对之间被观察。然而,令人惊讶地,靠近的类似在三显型的系的抄本表示侧面之间被观察,由一样的模式激活。而且,二个激活模式产生的 Th 房间系在他们基因表示的模式更加不同,由 microarray 分析监视了,但是与一样的激活模式产生的另外的显型的系展出了公共。这研究因此证明激活与 anti-CD3/CD28 抗体产生的(i) Th 系不同于 antigen/APC 产生的系;并且(ii ) 激活的模式决定主要抄本的表示侧面到大程度。 | Cuiyan Tan Lai Wei Barbara P Vistica Guangpu Shi Eric F Wawrousek Igal Gery | 2014 | Cellular & Molecular Immunology2014，11，3： | 1 |
| 18 | Bovaird deep^UV raman spectroscopic analysis of structure and dissolution rates of silica-rich sodiumborosilicate glasses显示文摘 | Chaiies F Windisch J Eric M P | | J Non-Cryst Solids t20ll0，357，： | 1 |
| 19 | Modeling ground heat flux in land surface parameterization schemes显示文摘 | Xu Laing Eric F Wood Dennis P Lettenmaier | 1999 | Journal of Geophysical Research1999，104，8： | 1 |
| 20 | Pharmacology and mechanism of action of pregabalin:the calcium channel alpha2-delta(alpha2-delta)subunit as a target for antiepileptic drug discovery显示文摘 | TAYLOR C P TIMOTHY A ERIC F | 2007 | Epilepsy Res2007，73，2： | 1 |
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