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| 1 | Small bowel tumors detected and missed during capsule endoscopy: Single center experience显示文摘AIM:To characterize small bowel(SB)tumors detected by capsule endoscopy(CE),and identify missed tumors.METHODS:The study included 145 consecutive patients in whom 150 CEs were performed.Following CE,the medical records of the study population were reviewed.Results of double-or single-balloon enteroscopy performed after CE and the results of surgery in all patients operated on were retrieved.The patients were contacted through telephone interviews or postal mail.In addition,the national cancer registry and the polish clinical gastrointestinal stromal tumor(GIST)Registry were searched to identify missed neoplasms.RESULTS:Indications for CE included overt and occult obscure gastrointestinal bleeding(n=81,53.7%),anemia(n=19,12.7%),malabsorption(n=18,12%),abnormal CB follow through(n=9,6%),abdominal pain(n=7,5%),celiac disease(n=5,3%),neuroendocrine tumor(n=3,2%),Crohn’s disease(n=2,<2%),Peutz-Jeghers syndrome(n=2,<2%),other polyposes(n=2,<2%),and diarrhea(n=2,<2%).The capsule reached the colon in 115(76.6%)examinations.In 150 investigations,CE identified 15SB tumors(10%),14 of which were operated on or treated endoscopically.Malignancies included metastatic melanoma(n=1),adenocarcinoma(n=2),and GIST(n=3).Benign neoplasms included dysplastic Peutz-Jeghers polyps(n=4).Non-neoplastic masses included venous malformation(n=1),inflammatory tumors(n=2),and a mass of unknown histology(n=1).During the follow-up period,three additional SB tumors were found(2 GISTs and one mesenteric tumor of undefined nature).The National Cancer Registry and Polish Clinical GIST Registry revealed no additional SB neoplasms in the post-examination period(follow-up:range 4.2-102.5 mo,median 39 mo).The sensitivity of CE for tumor detection was 83.3%,and the negative predictive value was 97.6%.The specificity and positive predictive value were both 100%.CONCLUSION:Neoplasms may be missed by CE,especially in the proximal SB.In overt obscure gastrointestinal bleeding,complementary endoscopic and/or radiologic diagnostic tests are indicated. | Edyta S Zagorowicz Anna M Pietrzak Ewa Wronska Jacek Pachlewski Piotr Rutkowski Ewa Kraszewska Jaroslaw Regula | 2013 | World Journal of Gastroenterology2013，19，47： | 10 |
| 2 | Lamivudine therapy for children with chronic hepatitis B显示文摘瞄准:为了估计,为失败到的有长期的肝炎 B (CHB ) 的孩子的 lamivudine 治疗的有效性和副作用对作出回应或有禁止徵候到 interferon-alpha (IFN-alpha ) 治疗。方法:有 CHB 的 59 个孩子被对待, 100 片 mg lamivudine 药片每天为 12 瞬间口头上地给一次。丙氨酸 aminotransferase (中高音) 活动在它的中止以后在治疗和每 3 瞬间期间每月被评估。HBe 抗原, anti-HBe 抗体,在浆液的 HBV DNA 水平在基线和每六个月被评估在期间并且在 lamivudine 治疗以后。对 lamivudine 治疗的持续病毒的反应(SVR ) 被定义为永久(比在治疗的结束以后的 6 瞬间不短) ,也就是中高音活动正规化,到 anti-HBe 抗体的 HBeAg 的 seroconversion,和在浆液的无法发现的病毒的 HBV-DNA (比 200 个拷贝低每 mL ) 。lamivudine 治疗的副作用的分析有关测试在治疗以后在治疗,和每 3 瞬间期间每月在临床的访问期间执行了的主观、客观的症状,临床的考试,和实验室用一张问询表在病人和他们的父母的会见之上被基于。结果:中高音 normalisation 发生在 47 (79.7%) 病人在之间第一和 11 (th ) 治疗的瞬间(吝啬的 4.4+/-2.95 瞬间,中部 4.0 瞬间) ,并且在 18 (30.5%) 他们在治疗的 2 瞬间以后。在中高音正规化和孩子们的年龄的时间之间没有关联, HBV 感染的年龄, HBV 感染的持续时间,发炎活动分数(分级) ,阶段,在治疗前的中高音活动,浆液 HBV DNA 水平,和 lamivudine 每体重的 kg 开。HBeAg/anti HBe seroconversion 在 27.1% 盒子中被完成。seroconversion 的更高的率与更低的浆液 HBV DNA 水平和 HBV 感染的更长的持续时间被连接。在 HBeAg/anti HBeAb seroconversion 和孩子们之间没有连接,分级是年龄, HBV 感染的年龄,阶段,在治疗前的中高音活动,和 lamivudnie 每体重的 kg 开。没有抱怨或临床的症状在 lamivudine 治疗期间被观察。肾的功能或骨髓中毒的效果的缺陷病人在没有被注意。结论:为有长期的肝炎 B 的孩子的一年 lamivudine 治疗有效、很好容忍。HBeAg/HBeAb 和 SVR 的 Seroconversion 与更低的预告的处理浆液 HBV DNA 水平被连接。 | Anna Liberek Anna Szaflarska-Poplawska Maria Korzon Gra(?)yna (?)uczak Magdalena Góra-Gebka Ewa (?)o(s|')-Rycharska Wanda Bako Mieczyslawa Czerwionka-Szaflarska | 2006 | World Journal of Gastroenterology2006，12，15： | 4 |
| 3 | ProGRP and NSE in therapy monitoring显示文摘 | Ewa W Jan K Beata S | 2008 | Anticancer Res2008，28，9： | 1 |
| 4 | Purine nueleoside phosphorylases: Properties, functions, and clinical aspects显示文摘 | Agnieszka B Ewa K David S | 2000 | Pharmacology Therapeutics2000，88，3： | 1 |
| 5 | Induction of apoptosis in human lung cancer cells by curcumin显示文摘 | G Radhakrishna Pillai Anand S Srivastava Tarek I Hassanein Dharam P Chauhan Ewa Carrier | 2004 | Cancer Letters2004，，2： | 1 |
| 6 | Gene expression and activity of antioxidant enzymes in the blood cells of workers who were occupationally exposed to lead显示文摘 | Aleksandra Kasperczyk Grzegorz Machnik Micha? Dobrakowski Daniel Sypniewski Ewa Birkner S?awomir Kasperczyk | 2012 | Toxicology (-)2012，，1： | 1 |
| 7 | Multiple cytokines and acute inflammation raise mouse leptin levels:Potential role in inflammatory anorexia显示文摘 | Robert CF Ewa MT | 1997 | J Exp Med1997，185，1： | 1 |
| 8 | Influence of green tea on erythrocytes antioxidant status of different age rats intoxicated withethanol 显示文摘 | Wojeiech L Ewa Z Elzbieta S | 2010 | Phytother Res2010，24，3： | 1 |
| 9 | Bradykinin stimulates MMP-2 production in guinea pig tracheal smooth muscle cells显示文摘 | Ewa Z Bichoy HG Pierre S | 2003 | Inflammation2003，27，5： | 1 |
| 10 | Copper-induced oxidative stress and antioxidant defence in Arabidopsis thaliana 显示文摘 | Maria D Ewa S Zbigniew K | 2004 | Biometals2004，17，4： | 1 |
| 11 | Rare earth element patterns in Nigerian coals显示文摘 | ELEGBA S B ADETUNJI J | 1996 | J Radioanal Nucl Chem1996，213，3： | 1 |
| 12 | Organic acids catalyzed po-- lymerization of e-caprolactone: Synthesis and characterization 显示文摘 | Oledzka Ewa Narine Suresh S | 2011 | J Appl Polym Sci2011，119，4： | 1 |
| 13 | Effect of growth regula-tors on postharvest characteristics of Zantedeschia aethiopica显示文摘 | Ewa S Aleksandra L Margrethe S | 2001 | Postharvest Biology and Technology2001，21，： | 1 |
| 14 | Isolation of mousehepatocyte:A Comparison of Antegrade and RetrogradePerfusion显示文摘 | Yin Z H Ewa C S Ellis Nowak G | 2007 | Cell Transplant2007，16，8： | 1 |
| 15 | Propionyl-L-Carnitine Improves Hemodynamics and Metabolic Markers of Cardiac Perfusion during Coronary Surgery in Diabetic Patients显示文摘 | Romuald Lango MD PhD Ryszard T. Smoleński Jan Rogowski Janusz Siebert Maria Wujtewicz Ewa M. S?omińska Wies?awa ?ysiak-Szyd?owska Magdi H. Yacoub | 2005 | Cardiovascular Drugs and Therapy2005，，4： | 1 |
| 16 | ELF magnetic fields initiatc protein tyrosine phosphorylation of the T cell receptor complex显示文摘 | Ewa L Mafia S Mats-Olof M | 2001 | Bioelectrochemistry2001，52，1： | 1 |
| 17 | PIT1-HinfI gene poly-morphism and its associations with milk production traitsin polish Black-and-White cattle显示文摘 | Andrzej D Iwona S Ewa C P | 2004 | Arch Tierz2004，47，： | 1 |
| 18 | The effect of cadmium on steroid hormones and their receptors in women with uterine myomas显示文摘 | Marzenna N Ewa S Anna N | 2011 | Arch Environ Cont-ain Toxicol2011，60，4： | 1 |
| 19 | Copper -induced Oxidative Stress and Antioxidant Defence in Arabidopsis Thaliana显示文摘 | MARIA D EWA S ZBIGNIEW K | 2004 | Biometal2004，17，4： | 1 |
| 20 | Early-phase im-munodetection of me tallothio- nein and heat shock proteins in ex-truded earthworm coelomocytes after d ermal expo- sure tometalions显示文摘 | Homa J Olchawa Ewa Sturzenbaum S R | 2005 | Environ Pollut2005，135，2： | 1 |
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